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Articles 13621 - 13650 of 13668

Full-Text Articles in Medicine and Health Sciences

Redesign And Prototype For The Interface Of A Volumetric Infusion Pump Following The Usability Engineering Lifecycle, Juliana Brixey, John Frenzel, Michael Chalambaga, Todd R. Johnson Jan 2002

Redesign And Prototype For The Interface Of A Volumetric Infusion Pump Following The Usability Engineering Lifecycle, Juliana Brixey, John Frenzel, Michael Chalambaga, Todd R. Johnson

Faculty, Staff and Student Publications

No abstract provided.


Evaluating A Medical Error Taxonomy, Juliana Brixey, Todd R. Johnson, Jiajie Zhang Jan 2002

Evaluating A Medical Error Taxonomy, Juliana Brixey, Todd R. Johnson, Jiajie Zhang

Faculty, Staff and Student Publications

Healthcare has been slow in using human factors principles to reduce medical errors. The Center for Devices and Radiological Health (CDRH) recognizes that a lack of attention to human factors during product development may lead to errors that have the potential for patient injury, or even death. In response to the need for reducing medication errors, the National Coordinating Council for Medication Errors Reporting and Prevention (NCC MERP) released the NCC MERP taxonomy that provides a standard language for reporting medication errors. This project maps the NCC MERP taxonomy of medication error to MedWatch medical errors involving infusion pumps. Of …


A History Of Health Informatics In The Texas Medical Center, Kirt Walker, Deepak Sagaram, James P. Turley Jan 2002

A History Of Health Informatics In The Texas Medical Center, Kirt Walker, Deepak Sagaram, James P. Turley

Faculty, Staff and Student Publications

No abstract provided.


Prognostic Model For Terminally Ill Cancer Patients On Laboratory Data, Kenji Hira, Noriaki Aoki, Akitoshi Hayashi, Janez Demsar, Blaz Zupan, Kim Dunn, William Jack Schull, Tsuguya Fukui Jan 2002

Prognostic Model For Terminally Ill Cancer Patients On Laboratory Data, Kenji Hira, Noriaki Aoki, Akitoshi Hayashi, Janez Demsar, Blaz Zupan, Kim Dunn, William Jack Schull, Tsuguya Fukui

Faculty, Staff and Student Publications

No abstract provided.


Evaluating The Prevalence, Content And Readability Of Complementary And Alternative Medicine (Cam) Web Pages On The Internet, Smitha Sagaram, Muhammad Walji, Elmer Bernstam Jan 2002

Evaluating The Prevalence, Content And Readability Of Complementary And Alternative Medicine (Cam) Web Pages On The Internet, Smitha Sagaram, Muhammad Walji, Elmer Bernstam

Faculty, Staff and Student Publications

Complementary and alternative medicine (CAM) use is growing rapidly. As CAM is relatively unregulated, it is important to evaluate the type and availability of CAM information. The goal of this study is to deter-mine the prevalence, content and readability of online CAM information based on searches for arthritis, diabetes and fibromyalgia using four common search engines. Fifty-eight of 599 web pages retrieved by a "condition search" (9.6%) were CAM-oriented. Of 216 CAM pages found by the "condition" and "condition + herbs" searches, 78% were authored by commercial organizations, whose pur-pose involved commerce 69% of the time and 52.3% had no …


Focusing Feedback On Interpersonal Skills: Practice Makes Perfect A Web-Based Tutorial For Standardized Patients, Tamara Owens, Zhong Xie, Peggy Gregg, Cynthia Phelps, Craig W. Johnson Jan 2002

Focusing Feedback On Interpersonal Skills: Practice Makes Perfect A Web-Based Tutorial For Standardized Patients, Tamara Owens, Zhong Xie, Peggy Gregg, Cynthia Phelps, Craig W. Johnson

Faculty, Staff and Student Publications

Focusing Feedback on Interpersonal Skills: Practice Makes Perfect is a Web-Based learning environment enabling standardized patients (SPs) to develop, practice and enhance constructive feedback skills. The Web-based training environment for SPs features realistic professional healthcare provider/patient video scenarios, graphics, audio and immediate feedback in a student-centered self-instructional environment. SPs, who are trained to simulate an illness and portray a patient in a realistic and consistent way, subsequently provide feedback from a patient's perspective to students undergoing communication and interpersonal skills training in health science fields like medicine and nursing.


Toward A Cognitive Taxonomy Of Medical Errors, Jiajie Zhang, Vimla L Patel, Todd R Johnson, Edward H Shortliffe Jan 2002

Toward A Cognitive Taxonomy Of Medical Errors, Jiajie Zhang, Vimla L Patel, Todd R Johnson, Edward H Shortliffe

Faculty, Staff and Student Publications

One critical step in addressing and resolving the problems associated with human errors is the development of a cognitive taxonomy of such errors. In the case of errors, such a taxonomy may be developed (1) to categorize all types of errors along cognitive dimensions, (2) to associate each type of error with a specific underlying cognitive mechanism, (3) to explain why, and even predict when and where, a specific error will occur, and (4) to generate intervention strategies for each type of error. Based on Reason's (1992) definition of human errors and Norman's (1986) cognitive theory of human action, we …


Comparing Communication Technology On Chinese, English, And Spanish Diabetes Web Sites, Yanko F Michea, Karen Pancheri, Yang Gong, Elmer Bernstam Jan 2002

Comparing Communication Technology On Chinese, English, And Spanish Diabetes Web Sites, Yanko F Michea, Karen Pancheri, Yang Gong, Elmer Bernstam

Faculty, Staff and Student Publications

Technological and cultural factors influence access to health information on the web in multifarious ways. We evaluated structural differences and availability of communication services on the web in three diverse language and cultural groups: Chinese, English, and Spanish. A total of 382 web sites were analyzed: 144 were English language sites (38%), 129 were Chinese language sites (34%), and 108 were Spanish language sites (28%). We did not find technical differences in the number of outgoing links per domain or the total availability of communication services between the three groups. There were differences in the distribution of available services between …


The Semantic Web And The Integration Of Health Data Resources, Rachel L. Richesson, James P. Turley, Mark S. Tuttle Jan 2002

The Semantic Web And The Integration Of Health Data Resources, Rachel L. Richesson, James P. Turley, Mark S. Tuttle

Faculty, Staff and Student Publications

No abstract provided.


Dental Postgraduates Prefer Hypertutorial Statistics Lessons In Randomized Web Course Comparisons, Craig W. Johnson Jan 2001

Dental Postgraduates Prefer Hypertutorial Statistics Lessons In Randomized Web Course Comparisons, Craig W. Johnson

Faculty, Staff and Student Publications

No abstract provided.


Cognitive Differences In Chart Reading: A Comparison Of Nurses And Physicians, Todd R. Johnson, Vimla L. Patel, James P. Turley Jan 2001

Cognitive Differences In Chart Reading: A Comparison Of Nurses And Physicians, Todd R. Johnson, Vimla L. Patel, James P. Turley

Faculty, Staff and Student Publications

This pilot study compares the mental models of a patient constructed by nurses and physicians while reading an electronic medical record. Preliminary results suggest that the participants' summaries were both quantitatively and qualitatively different. The physician made more inferences and focused on deeper relationships in the record, whereas the nurse focused on the descriptive surface structure of the record.


Persistent Productive Epstein‐Barr Virus Replication In Normal Epithelial Cells In Vivo, Dennis M. Walling, Catherine M. Flaitz, C. Mark Nichols, S. David Hudnall, Karen Adler-Storthz Jan 2001

Persistent Productive Epstein‐Barr Virus Replication In Normal Epithelial Cells In Vivo, Dennis M. Walling, Catherine M. Flaitz, C. Mark Nichols, S. David Hudnall, Karen Adler-Storthz

Faculty, Staff and Student Publications

Productive Epstein‐Barr virus (EBV) replication characterizes hairy leukoplakia, an oral epithelial lesion typically occurring in individuals infected with human immunodeficiency virus (HIV). Serial tongue biopsy specimens were obtained from HIV‐infected subjects before, during, and after valacyclovir treatment. EBV replication was detected by Southern hybridization to linear terminal EBV genome fragments, reverse‐transcriptase polymerase chain reaction amplification of EBV replicative gene transcripts, immunohistochemical detection of EBV replicative protein, and in situ hybridization to EBV DNA. EBV replication was detected in both hairy leukoplakia and normal tongue tissues. Valacyclovir treatment completely abrogated EBV replication in vivo, resulting in resolution of hairy leukoplakia when …


Preliminary Evaluation Of A Guideline Classification System, Elmer Bernstam, Nachman Ash, Mor Peleg, Samson Tu, Edward H. Shortliffe, Robert A. Greenes Jan 2001

Preliminary Evaluation Of A Guideline Classification System, Elmer Bernstam, Nachman Ash, Mor Peleg, Samson Tu, Edward H. Shortliffe, Robert A. Greenes

Faculty, Staff and Student Publications

In a previous paper, we presented a proposed expansion of the National Guideline Clearing-house (NGC) classification1. We performed a preliminary evaluation of the classification based on 100 guidelines randomly selected from the NGC collection. We found that 89 of the 100 guidelines could be assigned to a single guideline category. To test inter-observer agreement, twenty guidelines were also categorized by a second investigator. Agreement was found to be 40-90% depending on the axis, which compares favorably with agreement among MeSH indexers (30-60%)2. We conclude that categorization is feasible. Further research is needed to clarify axes with poor inter-observer agreement.


Focus Group Evaluation For Web-Based Courses, James P. Turley, Meena Hussein, Doris L. Ross Jan 2001

Focus Group Evaluation For Web-Based Courses, James P. Turley, Meena Hussein, Doris L. Ross

Faculty, Staff and Student Publications

No abstract provided.


Long-Term Regulation Of Neuronal High-Affinity Glutamate And Glutamine Uptake In Aplysia, J Levenson, S Endo, L S. Kategaya, R I. Fernandez, D G. Brabham, J Chin, J H. Byrne, A Eskin Nov 2000

Long-Term Regulation Of Neuronal High-Affinity Glutamate And Glutamine Uptake In Aplysia, J Levenson, S Endo, L S. Kategaya, R I. Fernandez, D G. Brabham, J Chin, J H. Byrne, A Eskin

Faculty, Staff and Student Publications

An increase in transmitter release accompanying long-term sensitization and facilitation occurs at the glutamatergic sensorimotor synapse of Aplysia. We report that a long-term increase in neuronal Glu uptake also accompanies long-term sensitization. Synaptosomes from pleural-pedal ganglia exhibited sodium-dependent, high-affinity Glu transport. Different treatments that induce long-term enhancement of the siphon-withdrawal reflex, or long-term synaptic facilitation increased Glu uptake. Moreover, 5-hydroxytryptamine, a treatment that induces long-term facilitation, also produced a long-term increase in Glu uptake in cultures of sensory neurons. The mechanism for the increase in uptake is an increase in the V(max) of transport. The long-term increase in Glu uptake …


Controlled Comparison Of Emergency Department Charting Software With A Case Simulation Comparator Model, Kirt Walker, Sridhar Rajappan, Todd R. Johnson Jan 2000

Controlled Comparison Of Emergency Department Charting Software With A Case Simulation Comparator Model, Kirt Walker, Sridhar Rajappan, Todd R. Johnson

Faculty, Staff and Student Publications

No abstract provided.


Comparison Of Abbreviated Injury Scale (Ais) And International Classification Of Diseases In Severe Trama Patients, Noriaki Aoki, Molly C. Shek, Todd R. Johnson, Martin A. Shreiber, John B. Holcomb, Matthew J. Wall, Richard W. Cone, Robert Beck Jan 2000

Comparison Of Abbreviated Injury Scale (Ais) And International Classification Of Diseases In Severe Trama Patients, Noriaki Aoki, Molly C. Shek, Todd R. Johnson, Martin A. Shreiber, John B. Holcomb, Matthew J. Wall, Richard W. Cone, Robert Beck

Faculty, Staff and Student Publications

No abstract provided.


Health Informatics Research & Evaluation Design Students Overwhelmingly Prefer Hypertutorial Web-Based Instruction In Randomized Comparison, Craig W. Johnson Jan 2000

Health Informatics Research & Evaluation Design Students Overwhelmingly Prefer Hypertutorial Web-Based Instruction In Randomized Comparison, Craig W. Johnson

Faculty, Staff and Student Publications

No abstract provided.


Java-Based World Wide Web Clinical Trial Data Management, Vinod Aggarwal, Venkatesh Rudrapatna, Craig W. Johnson Jan 2000

Java-Based World Wide Web Clinical Trial Data Management, Vinod Aggarwal, Venkatesh Rudrapatna, Craig W. Johnson

Faculty, Staff and Student Publications

No abstract provided.


The Web-Based Interactive Family History Questionnaire, Rita Torkzadeh, Constance M. Johnson, Craig W. Johnson Jan 2000

The Web-Based Interactive Family History Questionnaire, Rita Torkzadeh, Constance M. Johnson, Craig W. Johnson

Faculty, Staff and Student Publications

No abstract provided.


The 10 Commandments For Minimally Invasive Removal Of Nonmalignant Intracardiac Tumors, J Chin, A Angers, L J. Cleary, A Eskin, J H. Byrne May 1999

The 10 Commandments For Minimally Invasive Removal Of Nonmalignant Intracardiac Tumors, J Chin, A Angers, L J. Cleary, A Eskin, J H. Byrne

Faculty, Staff and Student Publications

Exogenous recombinant human transforming growth factor beta-1 (TGF-beta1) induced long-term facilitation of Aplysia sensory-motor synapses. In addition, 5-HT-induced facilitation was blocked by application of a soluble fragment of the extracellular portion of the TGF-beta1 type II receptor (TbetaR-II), which presumably acted by scavenging an endogenous TGF-beta1-like molecule. Because TbetaR-II is essential for transmembrane signaling by TGF-beta, we sought to determine whether Aplysia tissues contained TbetaR-II and specifically, whether neurons expressed the receptor. Western blot analysis of Aplysia tissue extracts demonstrated the presence of a TbetaR-II-immunoreactive protein in several tissue types. The expression and distribution of TbetaR-II-immunoreactive proteins in the central …


A Cbfa1-Dependent Genetic Pathway Controls Bone Formation Beyond Embryonic Development, P Ducy, M Starbuck, M Priemel, J Shen, G Pinero, V Geoffroy, M Amling, G Karsenty Apr 1999

A Cbfa1-Dependent Genetic Pathway Controls Bone Formation Beyond Embryonic Development, P Ducy, M Starbuck, M Priemel, J Shen, G Pinero, V Geoffroy, M Amling, G Karsenty

Faculty, Staff and Student Publications

The molecular mechanisms controlling bone extracellular matrix (ECM) deposition by differentiated osteoblasts in postnatal life, called hereafter bone formation, are unknown. This contrasts with the growing knowledge about the genetic control of osteoblast differentiation during embryonic development. Cbfa1, a transcriptional activator of osteoblast differentiation during embryonic development, is also expressed in differentiated osteoblasts postnatally. The perinatal lethality occurring in Cbfa1-deficient mice has prevented so far the study of its function after birth. To determine if Cbfa1 plays a role during bone formation we generated transgenic mice overexpressing Cbfa1 DNA-binding domain (DeltaCbfa1) in differentiated osteoblasts only postnatally. DeltaCbfa1 has a higher …


Intelligent Support Of Gait Analysis, Kathy A. Johnson, Sheldon R. Simon, Philip J. Smith, Jack W. Smith Jan 1999

Intelligent Support Of Gait Analysis, Kathy A. Johnson, Sheldon R. Simon, Philip J. Smith, Jack W. Smith

Faculty, Staff and Student Publications

No abstract provided.


Predicting The Risk Of Obesity Using A Bayesian Network, Christopher C. Bunn, Min Du, Keyi Niu, Todd R. Johnson, Walker S. Poston, John P. Foreyt Jan 1999

Predicting The Risk Of Obesity Using A Bayesian Network, Christopher C. Bunn, Min Du, Keyi Niu, Todd R. Johnson, Walker S. Poston, John P. Foreyt

Faculty, Staff and Student Publications

No abstract provided.


Web Browser Implements Unobtrusive Randomized Comparisons Of Instruction In Health Informatics Classroom, Craig W. Johnson Jan 1999

Web Browser Implements Unobtrusive Randomized Comparisons Of Instruction In Health Informatics Classroom, Craig W. Johnson

Faculty, Staff and Student Publications

No abstract provided.


Isolation Of Lautropia Mirabilis From Oral Cavities Of Human Immunodeficiency Virus-Infected Children, S. N. Rossmann, P. H. Wilson, J. Hicks, B. Carter, S. G. Cron, C. Simon, C. M. Flaitz, G. J. Demmler, W. T. Shearer, M. W. Kline Jun 1998

Isolation Of Lautropia Mirabilis From Oral Cavities Of Human Immunodeficiency Virus-Infected Children, S. N. Rossmann, P. H. Wilson, J. Hicks, B. Carter, S. G. Cron, C. Simon, C. M. Flaitz, G. J. Demmler, W. T. Shearer, M. W. Kline

Faculty, Staff and Student Publications

Lautropia mirabilis, a pleomorphic, motile, gram-negative coccus, has been isolated from the oral cavities of 32 of 60 (53.3%) children infected with human immunodeficiency virus (HIV) and 3 of 25 (12.0%) HIV-uninfected controls; the association of L. mirabilis isolation with HIV infection is significant (P < 0.001). All children in the study, both HIV-infected children and controls, were born to HIV-infected mothers. The presence of this bacterium was not associated with clinical disease in these children. The HIV-infected children with L. mirabilis did not differ from the HIV-infected children without L. mirabilis in immunological status, clinical status, or systemic medications. The role of HIV infection itself or concomitant factors in the establishment of L. mirabilis in the oral cavity remains to be elucidated.


Web Browser As Medical Educator/Researcher Using Html & Javascript, Craig W. Johnson, George Oser, Allan J. Abedor Jan 1998

Web Browser As Medical Educator/Researcher Using Html & Javascript, Craig W. Johnson, George Oser, Allan J. Abedor

Faculty, Staff and Student Publications

No abstract provided.


Phosphorylation Of Elongation Factor 1 And Ribosomal Protein S6 By Multipotential S6 Kinase And Insulin Stimulation Of Translational Elongation, Y W Chang, J A Traugh Nov 1997

Phosphorylation Of Elongation Factor 1 And Ribosomal Protein S6 By Multipotential S6 Kinase And Insulin Stimulation Of Translational Elongation, Y W Chang, J A Traugh

Faculty, Staff and Student Publications

Stimulation of protein synthesis in response to insulin is concomitant with increased phosphorylation of initiation factors 4B and 4G and ribosomal protein S6 (Morley, S. J., and Traugh, J. A. (1993) Biochimie 75, 985-989) and is due at least in part to multipotential S6 kinase. When elongation factor 1 (EF-1) from rabbit reticulocytes was examined as substrate for multipotential S6 kinase, up to 1 mol/mol of phosphate was incorporated into the alpha, beta, and delta subunits. Phosphorylation of EF-1 resulted in a 2-2. 6-fold stimulation of EF-1 activity, as measured by poly(U)-directed polyphenylalanine synthesis. The rate of elongation was also …


Estimation Of The Incidence Of A Rare Genetic Disease Through A Two-Tier Mutation Survey, R Chakraborty, M R Srinivasan, S Raskin Jun 1993

Estimation Of The Incidence Of A Rare Genetic Disease Through A Two-Tier Mutation Survey, R Chakraborty, M R Srinivasan, S Raskin

Faculty, Staff and Student Publications

Recent attempts to detect mutations involving single base changes or small deletions that are specific to genetic diseases provide an opportunity to develop a two-tier mutation-screening program through which incidence of rare genetic disorders and gene carriers may be precisely estimated. A two-tier survey consists of mutation screening in a sample of patients with specific genetic disorders and in a second sample of newborns from the same population in which mutation frequency is evaluated. We provide the statistical basis for evaluating the incidence of affected and gene carriers in such two-tier mutation-screening surveys, from which the precision of the estimates …


Can An Anesthesia Machine Flush Valve Provide For Effective Jet Ventilation?, S D Gaughan, J L Benumof, G T Ozaki Apr 1993

Can An Anesthesia Machine Flush Valve Provide For Effective Jet Ventilation?, S D Gaughan, J L Benumof, G T Ozaki

Faculty, Staff and Student Publications

Transtracheal jet ventilation (TTJV) using a percutaneously inserted intravenous (IV) catheter for the patient who cannot be ventilated or tracheally intubated or, using a jet stylet for changing endotracheal tubes (ETT) in patients for whom subsequent ventilation and/or tracheal reintubation may be difficult, are extremely valuable therapeutic options. The jet ventilation system must have a sufficiently high pressure-oxygen source to drive oxygen through noncompliant tubing and through relatively small IV catheters and/or jet stylets in order to achieve adequate ventilation and oxygenation. There is no evidence that using the common gas outlet of an anesthesia machine by activating the flush …