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- Genetic Polymorphisms and Antidepressant Adverse Effects (1)
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- Implications of the New ICSD-3 Diagnostic Criteria for Narcolepsy in Patients Diagnosed by ICSD-2 (1)
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Articles 1 - 6 of 6
Full-Text Articles in Medicine and Health Sciences
A Piece Of My Mind. A Piece Of My Mind--Actually., Herbert M. Adler
A Piece Of My Mind. A Piece Of My Mind--Actually., Herbert M. Adler
Department of Psychiatry and Human Behavior Faculty Papers
No abstract provided.
Implications Of The New Icsd-3 Diagnostic Criteria For Narcolepsy In Patients Diagnosed By Icsd-2, John Konikkara, Md, Robert Tavella, Mph, Rpsgt, William Breuninger, Rpsgt, Karl Doghramji, Md
Implications Of The New Icsd-3 Diagnostic Criteria For Narcolepsy In Patients Diagnosed By Icsd-2, John Konikkara, Md, Robert Tavella, Mph, Rpsgt, William Breuninger, Rpsgt, Karl Doghramji, Md
Department of Psychiatry and Human Behavior Faculty Papers
BACKGROUND
The ICSD-2 diagnostic criteria for narcolepsy mandated 2 sleep-onset REM periods (SOREMPs) on multiple sleep latency testing (MSLT). Subsequent data suggested that a SOREMP within 15 minutes of nocturnal sleep onset, in the absence of another sleep disorder, is a highly specific finding for narcolepsy, but with low sensitivity. Therefore, the diagnostic criteria for the ICSD-3 allow for a minimum of one SOREMP during the MSLT, provided that the preceding overnight polysomnogram (PSG) also exhibits 1 SOREMP. We sought to re-evaluate the effects of this revision on diagnostic sensitivity by retrospectively applying ICSD-3 diagnostic criteria to patients who had …
Clinical Management Of Insomnia, Karl Doghramji, Paul P. Doghramji
Clinical Management Of Insomnia, Karl Doghramji, Paul P. Doghramji
Department of Psychiatry and Human Behavior Faculty Papers
Throughout the book, we are guided by our main goal of providing practitioners with clinically relevant, evidence-based, and state-of-the-art information in the evaluation and management of insomnia. We have made a concerted attempt to ensure that our reviews are consistent with professional guidelines to the extent that current knowledge permits.
Genetic Polymorphisms And Antidepressant Adverse Effects, Rajnish Mago, S. Gupta, Kelly Huhn, R. Shah
Genetic Polymorphisms And Antidepressant Adverse Effects, Rajnish Mago, S. Gupta, Kelly Huhn, R. Shah
Department of Psychiatry and Human Behavior Faculty Papers
Abstract
Background
Aim: to assess whether pharmacogenetic polymorphisms are associated with increased adverse effects or non-response with certain antidepressants whose metabolism is highly dependent on specific CYP450 isoenzymes. This is interim analysis of an ongoing study
Methods
We used a Case Control design comparing patients with major depressive disorder or generalized anxiety disorder who had had increased adverse effects from specified antidepressants (Cases) to patients who were poor responders to an antidepressant but without significant adverse effects (Controls) Genecept Assay™ (battery of pharmacogenetic tests relevant to psychiatry) was obtained using saliva or cheek swab
Results
Importantly, 57.1% of Cases were …
Eleven Years Of Data On The Jefferson Scale Of Empathy-Medical Student Version (Jse-S): Proxy Norm Data And Tentative Cutoff Scores., Mohammadreza Hojat, Joseph S. Gonnella
Eleven Years Of Data On The Jefferson Scale Of Empathy-Medical Student Version (Jse-S): Proxy Norm Data And Tentative Cutoff Scores., Mohammadreza Hojat, Joseph S. Gonnella
Department of Psychiatry and Human Behavior Faculty Papers
OBJECTIVE: This study was designed to provide typical descriptive statistics, score distributions and percentile ranks of the Jefferson Scale of Empathy-Medical Student version (JSE-S) of male and female medical school matriculants to serve as proxy norm data and tentative cutoff scores.
SUBJECTS AND METHODS: The participants were 2,637 students (1,336 women and 1,301 men) who matriculated at Sidney Kimmel (formerly Jefferson) Medical College between 2002 and 2012, and completed the JSE at the beginning of medical school. Information extracted from descriptive statistics, score distributions and percentile ranks for male and female matriculants were used to develop proxy norm data and …
Underlying Construct Of Empathy, Optimism, And Burnout In Medical Students., Mohammadreza Hojat, Michael Vergare, Gerald A. Isenberg, Mitchell Cohen, John Spandorfer
Underlying Construct Of Empathy, Optimism, And Burnout In Medical Students., Mohammadreza Hojat, Michael Vergare, Gerald A. Isenberg, Mitchell Cohen, John Spandorfer
Department of Psychiatry and Human Behavior Faculty Papers
OBJECTIVE: This study was designed to explore the underlying construct of measures of empathy, optimism, and burnout in medical students.
METHODS: Three instruments for measuring empathy (Jefferson Scale of Empathy, JSE); Optimism (the Life Orientation Test-Revised, LOT-R); and burnout (the Maslach Burnout Inventory, MBI, which includes three scales of Emotional Exhaustion, Depersonalization, and Personal Accomplishment) were administered to 265 third-year students at Sidney Kimmel (formerly Jefferson) Medical College at Thomas Jefferson University. Data were subjected to factor analysis to examine relationships among measures of empathy, optimism, and burnout in a multivariate statistical model.
RESULTS: Factor analysis (principal component with oblique …