Medicine and Health Sciences | Open Access Articles

Cytokine Profiles Of Stimulated Blood Lymphocytes In Asthmatic And Healthy Adolescents Cross The School Year, Duck-Hee Kang, Christopher L. Coe, Donna O. Mccarthy, Nizar N. Jarjour, Elizabeth A. Kelly, Raymond R. Rodriguez, William W. Busse

College of Nursing Faculty Research and Publications

T cell cytokines play an important role in mediating airway inflammation in asthma. The predominance of a Th2 cytokine profile, particularly interleukin (IL)-4 and IL-5, is associated with the pathogenesis and course of asthma. The aim of this study was to test the hypothesis that a stressful life event alters the pattern of cytokine release in asthmatic individuals. Thirteen healthy controls and 21 asthmatic adolescents gave blood samples three times over a semester: midsemester, during the week of final examinations, and 2-3 weeks after examinations. Interferon-γ (IFN-γ), IL-2, IL-4, and IL-5 were measured from supernatants of cells stimulated with PHA/PMA …

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Adaptation Of The Doubly Labeled Water Method For Subjects Consuming Isotopically Enriched Water, Randall J. Gretebeck, Dale A. Schoeller, Rick A. Socki, Janis Davis-Street, Everett K. Gibson, Leslie O. Schulz, Helen W. Lane

College of Nursing Faculty Research and Publications

The use of doubly labeled water (DLW) to measure energy expenditure is subject to error if the background abundance of the oxygen and hydrogen isotope tracers changes during the test period. This study evaluated the accuracy and precision of different methods by which such background isotope changes can be corrected, including a modified method that allows prediction of the baseline that would be achieved if subjects were to consume water from a given source indefinitely. Subjects in this study were eight women (4 test subjects and 4 control subjects) who consumed for 28 days water enriched to resemble drinking water …

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