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Full-Text Articles in Medicine and Health Sciences

Treatment Adherence And Health Outcomes In Patients With Bronchiectasis, Amanda Mccullough, Michael Tunney, Alexander Quittner, Stuart Elborn, Judy Bradley, Carmel Hughes May 2014

Treatment Adherence And Health Outcomes In Patients With Bronchiectasis, Amanda Mccullough, Michael Tunney, Alexander Quittner, Stuart Elborn, Judy Bradley, Carmel Hughes

Amanda McCullough

Background: We aimed to determine adherence to inhaled antibiotics, other respiratory medicines and airway clearance and to determine the association between adherence to these treatments and health outcomes (pulmonary exacerbations, lung function and Quality of Life Questionnaire-Bronchiectasis [QOL-B]) in bronchiectasis after 12 months.Methods: Patients with bronchiectasis prescribed inhaled antibiotics for Pseudomonas aeruginosa infection were recruited into a one-year study. Participants were categorised as " adherent" to medication (medication possession ratio ≥80% using prescription data) or airway clearance (score ≥80% in the Modified Self-Reported Medication-Taking Scale). Pulmonary exacerbations were defined as treatment with a new course of oral or intravenous antibiotics …


Adherence To Treatment In Bronchiectasis: A Challenge That Physiotherapists Can’T Ignore, Amanda Mccullough, Judy Bradley Dec 2013

Adherence To Treatment In Bronchiectasis: A Challenge That Physiotherapists Can’T Ignore, Amanda Mccullough, Judy Bradley

Amanda McCullough

Adherence to treatment in bronchiectasis: a challenge that physiotherapists can't ignore Summary The purpose of this article is to highlight the importance for physiotherapists of patient adherence to treatment in bronchiectasis. This review provides evidence that adherence is important in bronchiectasis as it is low and affects health outcomes. We also show that there are a number of potentially modifiable factors that affect adherence that could be targeted through adherence interventions. The most effective methods of measuring adherence or interventions to enhance adherence are not known for bronchiectasis. Therefore, future research should focus on developing accurate and simple methods of …


Interventions For Enhancing Adherence To Treatment In Adults With Bronchiectasis (Protocol), Amanda Mccullough, Cristin Ryan, Judy Bradley, Brenda O'Neill, Stuart Elborn, Carmel Hughes Dec 2013

Interventions For Enhancing Adherence To Treatment In Adults With Bronchiectasis (Protocol), Amanda Mccullough, Cristin Ryan, Judy Bradley, Brenda O'Neill, Stuart Elborn, Carmel Hughes

Amanda McCullough

More than 600 million people worldwide suffer from chronic respiratory disease (WHO 2007), leading to 4.2 million deaths annually (WHO 2010). Bronchiectasis is an underdiagnosed and underinvestigated condition; research into new treatments is urgently required to improve the health status of patients with this condition (Gibson 2013). The global prevalence of bronchiectasis is currently not known. The most recent prevalence study, which was conducted in the United States, demonstrated that prevalence of the condition is increasing at a rate of 8.7% annually, with an eight-year prevalence of 1106 per 100,000 of the population (Seitz 2012). Bronchiectasis-associated annual healthcare costs are …