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Treatment Adherence And Health Outcomes In Patients With Bronchiectasis, Amanda Mccullough, Michael Tunney, Alexander Quittner, Stuart Elborn, Judy Bradley, Carmel Hughes
Treatment Adherence And Health Outcomes In Patients With Bronchiectasis, Amanda Mccullough, Michael Tunney, Alexander Quittner, Stuart Elborn, Judy Bradley, Carmel Hughes
Amanda McCullough
Background: We aimed to determine adherence to inhaled antibiotics, other respiratory medicines and airway clearance and to determine the association between adherence to these treatments and health outcomes (pulmonary exacerbations, lung function and Quality of Life Questionnaire-Bronchiectasis [QOL-B]) in bronchiectasis after 12 months.Methods: Patients with bronchiectasis prescribed inhaled antibiotics for Pseudomonas aeruginosa infection were recruited into a one-year study. Participants were categorised as " adherent" to medication (medication possession ratio ≥80% using prescription data) or airway clearance (score ≥80% in the Modified Self-Reported Medication-Taking Scale). Pulmonary exacerbations were defined as treatment with a new course of oral or intravenous antibiotics …