Medicine and Health Sciences Commons^™

“Why Would I Want To Go Out?”: Age-Related Vision Loss And Social Participation, Debbie Rudman, Deborah Gold, Colleen Mcgrath, Biljana Zuvela, Marlee Spafford, Rebecca Renwick

Occupational Therapy Publications

Social participation, a key determinant of healthy aging, is often negatively impacted by age-related vision loss (ARVL). This grounded theory study aimed to understand social participation as a process negotiated in everyday life by older adults with ARVL. Interviews, audio diaries, and life-space maps were used to collect data with 21 older adults in two Ontario cities. Inductive data analysis resulted in a transactional model of the process of negotiating social participation in context. This model depicts how environmental features and resources, skills and abilities, and risks and vulnerabilities transacted with values and priorities to affect if and how social …

Factors Influencing Communication And Decision-Making About Life-Sustaining Technology During Serious Illness: A Qualitative Study, Jennifer Kryworuchko, P. H. Strachan, E. Nouvet, J. Downar, J. J. You

Health Studies Publications

© 2016, BMJ Publishing Group. All rights reserved. Objectives: We aimed to identify factors influencing communication and decision-making, and to learn how physicians and nurses view their roles in deciding about the use of life-sustaining technology for seriously ill hospitalised patients and their families. Design: The qualitative study used Flanagan's critical incident technique to guide interpretive description of open-ended in-depth individual interviews. Setting: Participants were recruited from the medical wards at 3 Canadian hospitals. Participants: Interviews were completed with 30 healthcare professionals (9 staff physicians, 9 residents and 12 nurses; aged 25-63 years; 73% female) involved in decisions about the …

Advancing Health Promotion Pedagogy: A Multi-Step, Applied Health Promotion Classroom Project, Jennifer Irwin

Health Studies Publications

Courses that bridge health promotion scholarship with a demonstrative application of that scho- larship are potent and critical for future public health professionals. For senior students about to graduate from the Honors Bachelor of Health Sciences (BHSc) Program at Western University (Ontario, Canada), my intention was to create a course experience that marries health promotion scholarship with a practical skill-set in line with constructivist learning approaches. This article outlines a multi-component, classroom-based, population health group project for senior students enrolled in an Advanced Health Promotion course. Since its inception, the course has hosted 562 students and has received an average …

Design And Evaluation Of An Mri-Compatible Linear Motion Stage., Mohammad Ali Tavallaei, Patricia M Johnson, Junmin Liu, Maria Drangova

Medical Biophysics Publications

PURPOSE: To develop and evaluate a tool for accurate, reproducible, and programmable motion control of imaging phantoms for use in motion sensitive magnetic resonance imaging (MRI) appli cations.

METHODS: In this paper, the authors introduce a compact linear motion stage that is made of nonmagnetic material and is actuated with an ultrasonic motor. The stage can be positioned at arbitrary positions and orientations inside the scanner bore to move, push, or pull arbitrary phantoms. Using optical trackers, measuring microscopes, and navigators, the accuracy of the stage in motion control was evaluated. Also, the effect of the stage on image signal-to-noise …

Cost-Effectiveness Analysis Of Arthroscopic Surgery Compared With Non-Operative Management For Osteoarthritis Of The Knee, Jacquelyn D. Marsh, Trevor B. Birmingham, J. Robert Giffin

Bone and Joint Institute

No abstract provided.

Does Deep Cervical Flexor Muscle Training Affect Pain Pressure Thresholds Of Myofascial Trigger Points In Patients With Chronic Neck Pain? A Prospective Randomized Controlled Trial, Pavlos Bobos, Evdokia Billis, Dimitra Tania Papanikolaou, Constantinos Koutsojannis, Joy C. Macdermid

Bone and Joint Institute

© 2016 Pavlos Bobos et al. Background. We need to understand more about how DNF performs in different contexts and whether it affects the pain threshold over myofascial trigger points (MTrPs). Purpose. The objectives were to investigate the effect of neck muscles training on disability and pain and on pain threshold over MTrPs in people with chronic neck pain. Methods. Patients with chronic neck pain were eligible for participation with a Neck Disability Index (NDI) score of over 5/50 and having at least one MTrP on either levator scapulae, upper trapezoid, or splenius capitis muscle. Patients were randomly assigned into …

Efficacy Of Exercise Therapy In Workers With Rotator Cuff Tendinopathy: A Systematic Review, François Desmeules, Jennifer Boudreault, Clermont E. Dionne, Pierre Frémont, Véronique Lowry, Joy C. Macdermid, Jean Sébastien Roy

Bone and Joint Institute

Objective: To perform a systematic review of randomized controlled trials (RCTs) on the efficacy of therapeutic exercises for workers suffering from rotator cuff (RC) tendinopathy. Methods: A literature search in four bibliographical databases (Pubmed, CINAHL, EMBASE, and PEDro) was conducted from inception up to February 2015. RCTs were included if participants were workers suffering from RC tendinopathy, the outcome measures included work-related outcomes, and at least one of the interventions under study included exercises. The methodological quality of the studies was evaluated with the Cochrane Risk of Bias Assessment tool. Results: The mean methodological score of the ten included studies …

Research Priorities In The Field Of Posttraumatic Pain And Disability: Results Of A Transdisciplinary Consensus-Generating Workshop, David M. Walton, James M. Elliott, Joshua Lee, Eldon Loh, Joy C. Macdermid, Siobhan Schabrun, Walter L. Siqueira, Brian D. Corneil, Bill Aal, Trevor Birmingham, Amy Brown, Lynn K. Cooper, James P. Dickey, S. Jeffrey Dixon, Douglas D. Fraser, Joseph S. Gati, Gregory B. Gloor, Gordon Good, David Holdsworth, Samuel A. Mclean, Wanda Millard, Jordan Miller, Jackie Sadi, David A. Seminowicz, J. Kevin Shoemaker, Gunter P. Siegmund, Theodore Vertseegh, Timothy H. Wideman

Bone and Joint Institute

© Copyright 2016 David M.Walton et al. Background. Chronic or persistent pain and disability following noncatastrophic 'musculoskeletal' (MSK) trauma is a pervasive public health problem. Recent intervention trials have provided little evidence of benefit from several specific treatments for preventing chronic problems. Such findings may appear to argue against formal targeted intervention for MSK traumas. However, these negative findings may reflect a lack of understanding of the causal mechanisms underlying the transition from acute to chronic pain, rendering informed and objective treatment decisions difficult. The Canadian Institutes of Health Research (CIHR) Institute ofMusculoskeletalHealth and Arthritis (IMHA) has recently identified better …

Re-Evaluation Of Low Intensity Pulsed Ultrasound In Treatment Of Tibial Fractures (Trust): Randomized Clinical Trial, Jason W. Busse, Mohit Bhandari, Thomas A. Einhorn, Emil Schemitsch, James D. Heckman, Paul Tornetta, Kwok Sui Leung, Diane Heels-Ansdell, Sun Makosso-Kallyth, Gregory J. Della Rocca, Clifford B. Jones, Gordon H. Guyatt

Bone and Joint Institute

Objective: To determine whether low intensity pulsed ultrasound (LIPUS), compared with sham treatment, accelerates functional recovery and radiographic healing in patients with operatively managed tibial fractures. Design: A concealed, randomized, blinded, sham controlled clinical trial with a parallel group design of 501 patients, enrolled between October 2008 and September 2012, and followed for one year. Setting: 43 North American academic trauma centers. Participants: Skeletally mature men or women with an open or closed tibial fracture amenable to intramedullary nail fixation. Exclusions comprised pilon fractures, tibial shaft fractures that extended into the joint and required reduction, pathological fractures, bilateral tibial fractures, …

High Intensity Aerobic Exercise Training Improves Deficits Of Cardiovascular Autonomic Function In A Rat Model Of Type 1 Diabetes Mellitus With Moderate Hyperglycemia, Kenneth N. Grisé, T. Dylan Olver, Matthew W. Mcdonald, Adwitia Dey, Mao Jiang, James C. Lacefield, J. Kevin Shoemaker, Earl G. Noble, C. W.James Melling

Bone and Joint Institute

© 2016 Kenneth N. Grisé et al. Indices of cardiovascular autonomic neuropathy (CAN) in experimental models of Type 1 diabetes mellitus (T1DM) are often contrary to clinical data. Here, we investigated whether a relatable insulin-treated model of T1DM would induce deficits in cardiovascular (CV) autonomic function more reflective of clinical results and if exercise training could prevent those deficits. Sixty-four rats were divided into four groups: sedentary control (C), sedentary T1DM (D), control exercise (CX), or T1DM exercise (DX). Diabetes was induced via multiple low-dose injections of streptozotocin and blood glucose was maintained at moderate hyperglycemia (9-17 mM) through insulin …

Impaired Cerebrovascular Function In Coronary Artery Disease Patients And Recovery Following Cardiac Rehabilitation, Udunna C. Anazodo, J. K. Shoemaker, Neville Suskin, Tracy Ssali, Danny J.J. Wang, Keith S. St. Lawrence

Bone and Joint Institute

© 2016 Anazodo, Shoemaker, Suskin, Ssali, Wang and St. Lawrence. Coronary artery disease (CAD) poses a risk to the cerebrovascular function of older adults and has been linked to impaired cognitive abilities. Using magnetic resonance perfusion imaging, we investigated changes in resting cerebral blood flow (CBF) and cerebrovascular reactivity (CVR) to hypercapnia in 34 CAD patients and 21 age-matched controls. Gray matter volume (GMV)s were acquired and used as a confounding variable to separate changes in structure from function. Compared to healthy controls, CAD patients demonstrated reduced CBF in the superior frontal, anterior cingulate (AC), insular, pre- and post-central gyri, …

The Development And Validation Of A Multivariable Model To Predict Whether Patients Referred For Total Knee Replacement Are Suitable Surgical Candidates At The Time Of Initial Consultation, Laura Churchill, Samuel J. Malian, Bert M. Chesworth, Dianne Bryant, Steven J. Macdonald, Jacquelyn D. Marsh, J. Robert Giffin

Bone and Joint Institute

Background: In previous studies, 50%-70% of patients referred to orthopedic surgeons for total knee replacement (TKR) were not surgical candidates at the time of initial assessment. The purpose of our study was to identify and cross-validate patient self-reported predictors of suitability for TKR and to determine the clinical utility of a predictive model to guide the timing and appropriateness of referral to a surgeon. Methods: We assessed pre-consultation patient data as well as the surgeon's findings and post-consultation recommendations. We used multivariate logistic regression to detect self-reported items that could identify suitable surgical candidates. Results: Patients' willingness to undergo surgery, …

Visual Acceleration Perception For Simple And Complex Motion Patterns., Alexandra S Mueller, Brian Timney

Brain and Mind Institute Researchers' Publications

Humans are able to judge whether a target is accelerating in many viewing contexts, but it is an open question how the motion pattern per se affects visual acceleration perception. We measured acceleration and deceleration detection using patterns of random dots with horizontal (simpler) or radial motion (more visually complex). The results suggest that we detect acceleration better when viewing radial optic flow than horizontal translation. However, the direction within each type of pattern has no effect on performance and observers detect acceleration and deceleration similarly within each condition. We conclude that sensitivity to the presence of acceleration is generally …

Structural Brain Injury In Patients With Disorders Of Consciousness: A Voxel-Based Morphometry Study., Pieter Guldenmund, Andrea Soddu, Katherine Baquero, Audrey Vanhaudenhuyse, Marie-Aurélie Bruno, Olivia Gosseries, Steven Laureys, Francisco Gómez

Brain and Mind Institute Researchers' Publications

MAIN OBJECTIVE: Disorders of consciousness (DOC; encompassing coma, vegetative state/unresponsive wakefulness syndrome (VS/UWS) and minimally conscious state minus/plus (MCS-/+)) are associated with structural brain injury. The extent of this damage remains poorly understood and merits a detailed examination using novel analysis techniques. Research design/methods and procedures: This study used voxel-based morphometry (VBM) on structural magnetic resonance imaging scans of 61 patients with DOC to examine grey and white matter injury associated with DOC, time spent in DOC, aetiology and diagnosis.

MAIN OUTCOMES AND RESULTS: DOC and time spent in DOC were found to be associated with widespread structural brain injury, …

Correlation Between Resting State Fmri Total Neuronal Activity And Pet Metabolism In Healthy Controls And Patients With Disorders Of Consciousness., Andrea Soddu, Francisco Gómez, Lizette Heine, Carol Di Perri, Mohamed Ali Bahri, Henning U Voss, Marie-Aurélie Bruno, Audrey Vanhaudenhuyse, Christophe Phillips, Athena Demertzi, Camille Chatelle, Jessica Schrouff, Aurore Thibaut, Vanessa Charland-Verville, Quentin Noirhomme, Eric Salmon, Jean-Flory Luaba Tshibanda, Nicholas D Schiff, Steven Laureys

Brain and Mind Institute Researchers' Publications

INTRODUCTION: The mildly invasive 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) is a well-established imaging technique to measure 'resting state' cerebral metabolism. This technique made it possible to assess changes in metabolic activity in clinical applications, such as the study of severe brain injury and disorders of consciousness.

OBJECTIVE: We assessed the possibility of creating functional MRI activity maps, which could estimate the relative levels of activity in FDG-PET cerebral metabolic maps. If no metabolic absolute measures can be extracted, our approach may still be of clinical use in centers without access to FDG-PET. It also overcomes the problem of recognizing individual …

Microglia And Neurons In The Hippocampus Of Migratory Sandpipers., C G Diniz, N G M Magalhães, A A Sousa, C Santos Filho, D G Diniz, C M Lima, M A Oliveira, D C Paulo, P D C Pereira, D F Sherry, C W Picanço-Diniz

Brain and Mind Institute Researchers' Publications

The semipalmated sandpiper Calidris pusilla and the spotted sandpiper Actitis macularia are long- and short-distance migrants, respectively. C. pusilla breeds in the sub-arctic and mid-arctic tundra of Canada and Alaska and winters on the north and east coasts of South America. A. macularia breeds in a broad distribution across most of North America from the treeline to the southern United States. It winters in the southern United States, and Central and South America. The autumn migration route of C. pusilla includes a non-stop flight over the Atlantic Ocean, whereas autumn route of A. macularia is largely over land. Because of …

Context-Dependent Egr1 Expression In The Avian Hippocampus., Stephanie L Grella, Mélanie F Guigueno, David J White, David F Sherry, Diano F Marrone

Brain and Mind Institute Researchers' Publications

In mammals, episodic memory and spatial cognition involve context-specific recruitment of unique ensembles in the hippocampal formation (HF). Despite their capacity for sophisticated spatial (e.g., for migration) and episodic-like (e.g., for food-caching) memory, the mechanisms underlying contextual representation in birds is not well understood. Here we demonstrate environment-specific Egr1 expression as male brown-headed cowbirds (Molothrus ater) navigate environments for food reward, showing that the avian HF, like its mammalian counterpart, recruits distinct neuronal ensembles to represent different contexts.

Distinct Visual Processing Of Real Objects And Pictures Of Those Objects In 7- To 9-Month-Old Infants., Theresa M Gerhard, Jody C Culham, Gudrun Schwarzer

Brain and Mind Institute Researchers' Publications

The present study examined 7- and 9-month-old infants' visual habituation to real objects and pictures of the same objects and their preferences between real and pictorial versions of the same objects following habituation. Different hypotheses would predict that infants may habituate faster to pictures than real objects (based on proposed theoretical links between behavioral habituation in infants and neuroimaging adaptation in adults) or to real objects vs. pictures (based on past infant electrophysiology data). Sixty-one 7-month-old infants and fifty-nine 9-month-old infants were habituated to either a real object or a picture of the same object and afterward preference tested with …

Equal-Magnitude Size-Weight Illusions Experienced Within And Between Object Categories., Gavin Buckingham, Melvyn A Goodale, Justin A White, David A Westwood

Brain and Mind Institute Researchers' Publications

In the size-weight illusion (SWI), small objects feel heavier than larger objects of the same mass. This effect is typically thought to be a consequence of the lifter's expectation that the large object will outweigh the small object, because objects of the same type typically get heavier as they get larger. Here, we show that this perceptual effect can occur across object category, where there are no strong expectations about the correspondence between size and mass. One group of participants lifted same-colored large and small cubes with the same mass as one another, while another group lifted differently-colored large and …

Working Memory Training And Speech In Noise Comprehension In Older Adults., Rachel V Wayne, Cheryl Hamilton, Julia Jones Huyck, Ingrid S Johnsrude

Brain and Mind Institute Researchers' Publications

Understanding speech in the presence of background sound can be challenging for older adults. Speech comprehension in noise appears to depend on working memory and executive-control processes (e.g., Heald and Nusbaum, 2014), and their augmentation through training may have rehabilitative potential for age-related hearing loss. We examined the efficacy of adaptive working-memory training (Cogmed; Klingberg et al., 2002) in 24 older adults, assessing generalization to other working-memory tasks (near-transfer) and to other cognitive domains (far-transfer) using a cognitive test battery, including the Reading Span test, sensitive to working memory (e.g., Daneman and Carpenter, 1980). We also assessed far transfer to …

Medial Prefrontal And Anterior Insular Connectivity In Early Schizophrenia And Major Depressive Disorder: A Resting Functional Mri Evaluation Of Large-Scale Brain Network Models., Jacob Penner, Kristen A Ford, Reggie Taylor, Betsy Schaefer, Jean Théberge, Richard W J Neufeld, Elizabeth A Osuch, Ravi S Menon, Nagalingam Rajakumar, John M Allman, Peter C Williamson

Brain and Mind Institute Researchers' Publications

Anomalies in the medial prefrontal cortex, anterior insulae, and large-scale brain networks associated with them have been proposed to underlie the pathophysiology of schizophrenia and major depressive disorder (MDD). In this study, we examined the connectivity of the medial prefrontal cortices and anterior insulae in 24 healthy controls, 24 patients with schizophrenia, and 24 patients with MDD early in illness with seed-based resting state functional magnetic resonance imaging analysis using Statistical Probability Mapping. As hypothesized, reduced connectivity was found between the medial prefrontal cortex and the dorsal anterior cingulate cortex and other nodes associated with directed effort in patients with …

Aberrant Functional Connectivity Of The Amygdala Complexes In Ptsd During Conscious And Subconscious Processing Of Trauma-Related Stimuli, Daniela Rabellino, Maria Densmore, Paul A Frewen, Jean Theberge, Margaret C Mckinnon, Ruth A Lanius

Department of Medicine Publications

Post-traumatic stress disorder (PTSD) is characterized by altered functional connectivity of the amygdala complexes at rest. However, amygdala complex connectivity during conscious and subconscious threat processing remains to be elucidated. Here, we investigate specific connectivity of the centromedial amygdala (CMA) and basolateral amygdala (BLA) during conscious and subconscious processing of trauma-related words among individuals with PTSD (n = 26) as compared to non-trauma-exposed controls (n = 20). Psycho-physiological interaction analyses were performed using the right and left amygdala complexes as regions of interest during conscious and subconscious trauma word processing. These analyses revealed a differential, context-dependent responses by each amygdala …

Acc Neuro-Over-Connectivity Is Associated With Mathematically Modeled Additional Encoding Operations Of Schizophrenia Stroop-Task Performance, Reggie Taylor, Jean Theberge, Peter C Williamson, Maria Densmore, Richard W J Neufeld

Department of Medicine Publications

Functional magnetic resonance imaging at 7.0 Tesla was undertaken among Schizophrenia participants (Sz), and clinical (major mood disorder; MDD) and healthy controls (HC), during performance of the Stoop task. Stroop conditions included congruent and incongruent word color items, color-only items, and word-only items. Previous modeling results extended to this most widely used selective-attention task. All groups executed item-encoding operations (subprocesses of the item encoding process) at the same rate (performance accuracy being similarly high throughout), thus displaying like processing capacity; Sz participants, however, employed more subprocesses for item completions than did the MDD participants, who in turn used more subprocesses …

Consensus Classifications Of Gross Motor, Manual Ability, And Communication Function Classification Systems Between Therapists And Parents Of Children With Cerebral Palsy., Doreen J Bartlett, Barbara Galuppi, Robert J Palisano, Sarah Westcott Mccoy

Physical Therapy Publications

No abstract provided.

A Trial Of Wound Irrigation In The Initial Management Of Open Fracture Wounds, Mohit Bhandari, Kyle J. Jeray, Brad A. Petrisor, P. J. Devereaux, Diane Heels-Ansdell, Emil H. Schemitsch, Jeff Anglen, Gregory J. Della Rocca, Clifford Jones, Hans Kreder, Susan Liew, Paula Mckay, Steven Papp, Parag Sancheti, Sheila Sprague, Trevor B. Stone, Xin Sun, Stephanie L. Tanner, Paul Tornetta, Ted Tufescu, Stephen Walter, Gordon H. Guyatt

Bone and Joint Institute

Copyright © 2015 Massachusetts Medical Society. BACKGROUND The management of open fractures requires wound irrigation and dridement to remove contaminants, but the effectiveness of various pressures and solutions for irrigation remains controversial. We investigated the effects of castile soap versus normal saline irrigation delivered by means of high, low, or very low irrigation pressure. METHODS In this study with a 2-by-3 factorial design, conducted at 41 clinical centers, we randomly assigned patients who had an open fracture of an extremity to undergo irrigation with one of three irrigation pressures (high pressure [>20 psi], low pressure [5 to 10 psi], …

Declining Incidence Of Stroke And Dementia: Coincidence Or Prevention Opportunity?, Luciano A. Sposato, Moira K. Kapral, Jiming Fang, Sudeep S. Gill, Daniel G. Hackam, Lauren E. Cipriano, Vladimir Hachinski

Anatomy and Cell Biology Publications

No abstract provided.

Factors Impacting Transgender Patients’ Discomfort With Their Family Physicians: A Respondent-Driven Sampling Survey, Greta R. Bauer, Xuchen Zong, Ayden I. Scheim, Rebecca Hammond, Amardeep Thind

Epidemiology and Biostatistics Publications

BACKGROUND: Representing approximately 0.5% of the population, transgender (trans) persons in Canada depend on family physicians for both general and transition-related care. However, physicians receive little to no training on this patient population, and trans patients are often profoundly uncomfortable and may avoid health care. This study examined factors associated with patient discomfort discussing trans health issues with a family physician in Ontario, Canada.

METHODS: 433 trans people age 16 and over were surveyed using respondent-driven sampling for the Trans PULSE Project; 356 had a family physician. Weighted logistic regression models were fit to produce prevalence risk ratios (PRRs) via …

The Child And Adolescent Scale Of Environment (Case): Further Validation With Youth Who Have Chronic Conditions, Gary Bedell, Janette Mcdougal

Occupational Therapy Publications

Objective: To further validate the Child and Adolescent Scale of Environment (CASE).

Methods: Baseline data (n = 430) were analyzed from a longitudinal study on quality of life for youth with chronic conditions ages 11–17 in Ontario, Canada. Internal consistency and structure, and convergent and discriminant validity were examined via Cronbach’s alpha (α), exploratory factor analyses, correlation analyses and ANOVA.

Results: The CASE had high internal consistency (α = 0.89). A three-factor solution was produced with 55% variance explained: (1) Community/Home Resources, (2) School Resources and (3) Physical Design/Access). CASE total and factor …

Estimating Osteoporotic Fracture Risk Following A Wrist Fracture: A Tale Of Two Systems, Karen Beattie, Jonathan Adachi, George Ioannidis, Alexandra Papaioannou, William D. Leslie, Ruby Grewal, Joy Macdermid, Anthony B. Hodsman

Bone and Joint Institute

© 2015, The Author(s). Summary: The WHO fracture risk assessment (FRAX) and Canadian Association of Radiologists and Osteoporosis Canada (CAROC) tools can both be used to determine an individual’s 10-year risk of osteoporotic fracture. However, these tools differ in their risk calculation. For participants fracture, FRAX provides a lower fracture risk estimate than CAROC resulting in fewer decisions to initiate therapy.Purpose: The purpose of the current report is to compare fracture risk prediction rates using the CAROC and the FRAX® tools.Methods: Individuals ≥50 years with a distal radius fracture resulting from a fall from standing height or less were recruited …

Functional Outcomes Of Acutely Infected Knee Arthroplasty: A Comparison Of Different Surgical Treatment Options, Ivan Dzaja, James Howard, Lyndsay Somerville, Brent Lanting

Bone and Joint Institute

© 2015 8872147 Canada Inc. Background: An infected total knee arthroplasty (TKA) can be treated with irrigation and débridement with polyethylene exchange (IDPE) or a 2-staged revision (2SR). Although research has examined infection eradication rates of both treatments, patient outcomes have not been reported. We examined patient-reported outcomes following treatment compared with matched, noninfected controls. Methods: We retrospectively identified patients with infected TKAs who had undergone the index procedure between May 1991 and November 2011. Patient-reported outcomes included the 12-item Short Form Health Survey, Western Ontario and McMaster Universities Arthritis Index, and Knee Society Scores as well as range of …