Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Rehabilitation and Therapy (80)
- Occupational Therapy (77)
- Education (19)
- Arts and Humanities (15)
- Medical Specialties (11)
-
- Social and Behavioral Sciences (11)
- Art and Design (9)
- Dietetics and Clinical Nutrition (8)
- Mental and Social Health (8)
- Fashion Design (7)
- Communication Sciences and Disorders (5)
- Nursing (5)
- Speech Pathology and Audiology (5)
- Higher Education (4)
- Life Sciences (4)
- Physical Therapy (4)
- Psychology (4)
- Curriculum and Instruction (3)
- Health and Physical Education (3)
- Music (3)
- Music Therapy (3)
- Physical Sciences and Mathematics (3)
- Psychiatry and Psychology (3)
- Sociology (3)
- Speech and Hearing Science (3)
- Sports Medicine (3)
- Applied Behavior Analysis (2)
- Biology (2)
- International and Comparative Education (2)
- Keyword
-
- Occupational therapy (25)
- Education (5)
- Art (4)
- Occupation (4)
- Occupational therapist (4)
-
- Assistive technology (3)
- Rehabilitation (3)
- Traumatic brain injury (3)
- Adolescents (2)
- Assessment (2)
- Autism (2)
- Collaboration (2)
- Concussion (2)
- Culture (2)
- Evidence-based practice (2)
- Higher education (2)
- International (2)
- Leadership (2)
- Motherhood (2)
- Music therapy (2)
- Occupational justice (2)
- Participation (2)
- Philosophy (2)
- Quality of life (2)
- Simulation (2)
- Spirituality (2)
- Students (2)
- 2010 NCAA concussion policy (1)
- ACA (1)
- Abuse (1)
- Publication
- Publication Type
Articles 31 - 60 of 127
Full-Text Articles in Medicine and Health Sciences
Gobal Reproductive And Sexual Health, Kelly Ackerson
Gobal Reproductive And Sexual Health, Kelly Ackerson
Academic Leadership Academy
Goal
Gain hands-on practical knowledge and skills to advance the science of global reproductive & sexual health through state-of-the science lectures, discussion, case-studies, and small group work. Designed to provide training in key topics relevant to reproductive & sexual health in the global arena.
Objectives
i.Understand the paradigm of global reproductive & sexual health ii.Identify conceptual frameworks that are useful for global reproductive & sexual health studies iii.Understand how to design impactful studies iv.Discuss different measurement aspects of a study v.Understand the principals of proposal writing for funding vi.Become familiar with the use of big data
Contemplative Pedagogy In The Classroom: Engaging Students’ Self-Awareness To Enhance Learning, Michele Mcgrady
Contemplative Pedagogy In The Classroom: Engaging Students’ Self-Awareness To Enhance Learning, Michele Mcgrady
Academic Leadership Academy
Contemplative pedagogy offers unique opportunities for students to deepen their understanding and focus through introspection, reflection, and stillness. Contemplative practices, such as meditative exercises, movement, and writing allow students to understand the nature of their minds and the learning process. Through the use of contemplative practices, students experience increased attention, connection, creativity, as well as a deeper understanding of course material. Although critics may question the appropriateness of these practices in the classroom, contemplative pedagogy has the ability to positively impact students’ learning. This presentation invites participants to explore contemplative pedagogy and discuss ways to integrate practices into learning activities.
Grandparent Caregivers’ Perceptions And Lived Experiences: Their Health And Wellbeing, Access To Health And State Of Health Services In Zimbabwe, Magen M. Mutepfa Dr
Grandparent Caregivers’ Perceptions And Lived Experiences: Their Health And Wellbeing, Access To Health And State Of Health Services In Zimbabwe, Magen M. Mutepfa Dr
GrandFamilies: The Contemporary Journal of Research, Practice and Policy
The study explored the perceptions and lived experiences of self-rated health, access to health, and state of health services for grandparent caregivers in Zimbabwe. In–depth interviews using semi-structured interview guides were carried out to elicit perceptions of lived experiences from grandparent caregivers (N=31; Mean age= 65.7; SD= 10.7). The data was thematically analysed and the software Nvivo 10 was used to help categorize emergent themes. The study found that grandparent caregivers experienced multiple chronic and complex self-rated health conditions (e.g., High blood pressure (HBP), arthritis, diabetes, hypertension, back pain, and heart problems), which influenced their health and Quality of Life …
Conflicts, Concerns And Family Circumstances In Custodial Grandmothers Over 8 Years, Cristina Noriega, Carol Musil, Jaclene Zauszniewski, Camille Warner
Conflicts, Concerns And Family Circumstances In Custodial Grandmothers Over 8 Years, Cristina Noriega, Carol Musil, Jaclene Zauszniewski, Camille Warner
GrandFamilies: The Contemporary Journal of Research, Practice and Policy
Although many grandmothers raising grandchildren experience transitions in their roles as family strains and circumstances change, little longitudinal data has been examined. This qualitative study assessed the relationships between custodial grandmothers’ appraisals of their family conflicts and concerns and family circumstances across eight years. Participants were thirty-five Ohio grandmothers who were raising their grandchildren in 2006-2007 and provided additional self-report survey data in 2008-2009 and 2014-2015. Data were gathered from open-ended questions that were analyzed through conventional content analysis. The reported concerns were financial and emotional difficulties, grandchildren outcomes, mental and physical health of the grandchild and other family members, …
Kinship Diversion In The District Of Columbia: A Review Of Local Practice To Inform National Policy, Marla P. Spindel, Beth A. Stekler, Stephanie Ridgway Mcclellan
Kinship Diversion In The District Of Columbia: A Review Of Local Practice To Inform National Policy, Marla P. Spindel, Beth A. Stekler, Stephanie Ridgway Mcclellan
GrandFamilies: The Contemporary Journal of Research, Practice and Policy
This article addresses a practice commonly known in the child welfare community as “kinship diversion,” where a child welfare agency informally places children with relatives as an alternative to foster care. While evidence predominantly shows that abused and neglected children have better outcomes when they are placed with relatives when they cannot remain safely at home, serious concerns about these children’s safety and well-being arise when the placement with relatives is informal. Indeed, it is often not understood that these same relatives can be approved as foster parents and can receive essential financial assistance and supportive services to help safely …
Wmu To Expand Offerings In Youth And Community Development, College Of Education And Human Development
Wmu To Expand Offerings In Youth And Community Development, College Of Education And Human Development
Family and Consumer Sciences News
Youth and community development (YCD) is a quickly-professionalizing field, and WMU’s new master of arts degree and graduate certificate program in the College of Education and Human Development complete a continuum of community-based professional development opportunities available at the university.
Beta-Testing Of An Interactive Multimedia Computer Program Of Exposure Therapy For Ptsd, Marie C. Barrett
Beta-Testing Of An Interactive Multimedia Computer Program Of Exposure Therapy For Ptsd, Marie C. Barrett
Dissertations
Posttraumatic Stress Disorder (PTSD) results in significant impairment for the individual and substantial costs to society. Research indicates that cognitive behavioral psychotherapy (CBT) is the most effective treatment for PTSD and that among CBT treatments, exposure therapy is the treatment technique with the strongest evidence to recommend it for PTSD treatment. Computerized programs that deliver evidenced-based treatments offer a potential solution to barriers that prevent individuals from accessing and completing treatment. The present study evaluates the clinical and practical functionality of a computer-based program designed for the treatment of PTSD. Results indicate that completion of the program is associated with …
Training Pediatric Primary Care Providers In Behavior Management Strategies, Kate Burger
Training Pediatric Primary Care Providers In Behavior Management Strategies, Kate Burger
Dissertations
Childhood mental health disorders are a significant public health concern in the United States. It is estimated that every year 13 to 20% of children living in the United States experience a mental health disorder (National Research Council and Institute of Medicine, 2009). Despite the clear need for mental health care, less than half (45.6%) of children with one or more emotional, behavioral, or developmental conditions receive treatment from a mental health professional (The National Survey of Children's Health, 2007). There is growing evidence that integrating mental health services into pediatric primary care can result in increased treatment access as …
Qualitative Analogue Study On Student Therapist’S Reactions To Client Suicidality, Cynthia A. Beevers
Qualitative Analogue Study On Student Therapist’S Reactions To Client Suicidality, Cynthia A. Beevers
Dissertations
Suicidal clients are a reality for both professional and student therapists providing counseling (Chemtob et al., 1988; Dexter-Mazza & Freeman, 2003; Goodman, 1995; Howard, 2000; Jacobson, Ting, Sanders, & Harrington, 2004; Kleespies, Penk, & Forsyth, 1993; Kleespies, Smith, & Becker, 1990; Mackelprang, Karle, & Cash, 2014; McAdams & Foster, 2000). Previous research has investigated the experiences of professional therapists working with suicidal clients, but little is known about student therapists’ experiences with suicidal clients. Only two studies were found investigating the experiences of student therapists working with suicidal clients (Kleespies et al., 1993; Kleespies et al., 1990). However, in the …
Demonstrating Functional Analytic Psychotherapy As An Independent Variable In Efficacy Research: A New Measure Of Treatment Fidelity, Lindsey E. Knott
Demonstrating Functional Analytic Psychotherapy As An Independent Variable In Efficacy Research: A New Measure Of Treatment Fidelity, Lindsey E. Knott
Dissertations
Functional Analytic Psychotherapy (FAP) is a contextual behavior therapy that takes an in session, in vivo focus to improve client outcomes. This in vivo (IV) focus is distinctive of FAP and involves the therapist utilization of contingencies in session to decrease problematic response classes and increase more adaptive response classes (i.e., a differential reinforcement procedure). This contingent responding is proposed to be FAP’s mechanism of action leading to client change. FAP efficacy research mainly consists of small n single-case studies or group designs combing FAP with another CBT intervention. Maitland & Gaynor (2012) offered recommendations for increasing FAP efficacy research, …
Incidence Of Head Injury Among Synchronized Skaters: Rates, Risks, And Behaviors, Gretchen L. Mohney
Incidence Of Head Injury Among Synchronized Skaters: Rates, Risks, And Behaviors, Gretchen L. Mohney
Dissertations
Data regarding risk and rates for head injury and concussion specific to the sport of synchronized skating is absent from literature. This study investigated the rate and risk for head injury and concussion as a function of team level, identified behaviors to include education, neurocognitive baseline screening and protective equipment utilization, and the implementation of return to sport protocols.
An anonymous cross-sectional survey was implemented at the 2018 U.S. Synchronized Skating Championships. Participants were female members of a qualifying team, ages 13 and older, at the intermediate participation level and higher. The survey response rate was 42% (520/1232). Among the …
Primary Care Physician Delivered Brief Behavioral Intervention For Adult Obesity And Associated Health Conditions, Julia C. Huston
Primary Care Physician Delivered Brief Behavioral Intervention For Adult Obesity And Associated Health Conditions, Julia C. Huston
Dissertations
Obesity is a chronic health condition with prevalence rates that have continued to rise steadily over the past 30 years to the point that it has now been declared a global epidemic and a serious public health concern. Obesity is associated with significant physical and economic costs, primarily resulting from co-occurring health conditions that increase the risk of morbidity including type II diabetes, hypertension, dyslipidemia, stroke, coronary heart disease, and respiratory problems. Despite the dissemination of several obesity treatments, including pharmacotherapy, lifestyle modification, and bariatric surgery, the prevalence and severity of obesity continues to rise. Federal guidelines recommend the use …
The Relationship Between Hypermobile Joints And Tendonitis, Rachel Braden, Nicole Coughlin
The Relationship Between Hypermobile Joints And Tendonitis, Rachel Braden, Nicole Coughlin
Occupational Therapy Graduate Student Evidenced-Based Research Reviews
No abstract provided.
Wmu Student Aims To Clean Up The Fashion Industry, College Of Education And Human Development
Wmu Student Aims To Clean Up The Fashion Industry, College Of Education And Human Development
Family and Consumer Sciences News
Western Michigan University - undergraduate student Avery Green. His fashion startup, House of Pariah, goes against the grain, selling nonconformity and placing an emphasis on sustainability and inclusion.
Overcoming Barriers By Doing Things Differently, Jennifer Fortuna
Overcoming Barriers By Doing Things Differently, Jennifer Fortuna
The Open Journal of Occupational Therapy
Tom Yendell, an artist based in Hampshire, England, provided the cover art for the Summer 2018 issue of The Open Journal of Occupational Therapy (OJOT). “Silk Flowers” is a mouth painting made from acrylic on silk. Born a bilateral congenital amputee, Tom has learned to use his toes the same ways others use their hands. Tom relies little on aids and adaptations in his everyday life. He believes learning to do things your own way is empowering. As a world-renowned mouth and foot painter, Tom is a living example of how barriers can be overcome by doing things differently. Through …
Development And Evaluation Of A Collaborative Model Level Ii Fieldwork Program, Annmarie T. Kinsella, Catherine V. Piersol
Development And Evaluation Of A Collaborative Model Level Ii Fieldwork Program, Annmarie T. Kinsella, Catherine V. Piersol
The Open Journal of Occupational Therapy
This project developed a Collaborative Model Level II Fieldwork (CM-FWII) program to evaluate the effect of the program on fieldwork educator and student understanding of the model and changes in knowledge, perceptions, and satisfaction. Four fieldwork educators (FWEd) were recruited from two pediatric and two adult practice settings. Eight occupational therapy (OT) students met participation criteria and agreed to participate. A pre/post design was used to evaluate change in knowledge and perceptions. Satisfaction with the collaborative model (CM) was examined after the 12-week fieldwork rotation. Analysis procedures included a priori coding, calculation of frequency distributions, and thematic analysis of transcribed …
Sexual Functioning In Occupational Therapy Education: A Survey Of Programs, Kate Eglseder, Sheridan Webb, Miranda Rennie
Sexual Functioning In Occupational Therapy Education: A Survey Of Programs, Kate Eglseder, Sheridan Webb, Miranda Rennie
The Open Journal of Occupational Therapy
Despite the importance of sexuality to overall quality of life and well-being for individuals with disabilities, occupational therapy practitioners continue to under-address this issue. One possibility for the lack of attention in this area is the comfort and knowledge level of practitioners. In their seminal work, Payne, Greer, and Corbin (1988) surveyed occupational therapy programs in the United States in an effort to identify the amount of sexuality education provided. This study was aimed at identifying current trends in the provision of sexuality education for occupational therapy students. Despite the nearly 30-year gap in this area of research, and the …
How Service Dogs Enhance Veterans’ Occupational Performance In The Home: A Qualitative Perspective, Terry K. Crowe, Mylinh T. Nguyen, Brenda G. Tryon, Stephanie Barger, Victoria Sanchez
How Service Dogs Enhance Veterans’ Occupational Performance In The Home: A Qualitative Perspective, Terry K. Crowe, Mylinh T. Nguyen, Brenda G. Tryon, Stephanie Barger, Victoria Sanchez
The Open Journal of Occupational Therapy
Background: This qualitative study explored the lives of veterans diagnosed with posttraumatic stress disorder (PTSD) and/or traumatic brain injury (TBI) and how the partnerships with their service dogs supported improved occupational performance in their homes.
Method: Semi-structured individual interviews were conducted with six veterans with PTSD and/or TBI who graduated and received their service dogs from the Paws and Stripes Program in Albuquerque, NM. Home activities of daily living (self-care, household tasks, leisure activities, and family and friend relationships) guided the interview questions. The individual interviews were audio recorded, transcribed, and coded using qualitative data analysis software. Preliminary themes were …
Levels Of Arousal In Positive Moods: Effects On Motor Performance, Carolina Valencia, Krista Currier, Sarah Lindsay, Pamela Lemperis, Titus Hughes, Jeanne Sowers
Levels Of Arousal In Positive Moods: Effects On Motor Performance, Carolina Valencia, Krista Currier, Sarah Lindsay, Pamela Lemperis, Titus Hughes, Jeanne Sowers
The Open Journal of Occupational Therapy
Background: The use of simple preparatory methods, such as listening to relaxing music, may decrease negative emotions and enhance performance. The purpose of this research was to explore whether certain types of music, as a preparatory task, could enhance motor performance.
Method: Fifty-six participants were randomly assigned to a condition before completing a pre and postdexterity test using the Purdue Pegboard Test (PPT). Performance was assessed with the PPT and arousal of mood was assessed with the Affect Grid. During the postdexterity test, the participants heard no music or specific music based on their condition. The experimental conditions …
Use Of Neuromuscular Electrical Stimulation In The Treatment Of Neonatal Brachial Plexus Palsy: A Literature Review, Denise Justice, Jonathan Awori, Spencer Carlson, Kate W-C Chang, Lynda J-S Yang
Use Of Neuromuscular Electrical Stimulation In The Treatment Of Neonatal Brachial Plexus Palsy: A Literature Review, Denise Justice, Jonathan Awori, Spencer Carlson, Kate W-C Chang, Lynda J-S Yang
The Open Journal of Occupational Therapy
Background: The purpose of this study was to conduct a review of current literature on the effectiveness of neuromuscular electrical stimulation (NMES) for restoring motion and function in neonatal brachial plexus palsy (NBPP).
Method: A database search was conducted for NMES articles published between 1947 and 2015. Pre and posttreatment data were extracted for muscle power, active range of motion (AROM), and morphometric measurements.
Results: An initial search yielded 2,721 articles. A further title/abstract review produced 27 articles; of these, four met the inclusion criteria. Treatment protocols varied. There were no changes in average Medical Research Council …
Increasing Competency For Parents Of Adolescents With Executive Functioning Deficits: Enhancing Occupational Performance With Mindfulness, Kimberly S. Mollo, Bernardo A. Merizalde, Jennifer E. Lape
Increasing Competency For Parents Of Adolescents With Executive Functioning Deficits: Enhancing Occupational Performance With Mindfulness, Kimberly S. Mollo, Bernardo A. Merizalde, Jennifer E. Lape
The Open Journal of Occupational Therapy
Background: Executive functions are higher order cognitive processes occurring in the frontal lobe that influence cognitive, emotional, and behavioral functions. Adolescents with executive functioning deficits are at risk for difficulties in all domains of occupational functioning. Parents of these adolescents often live in a persistent state of stress that leads to highly reactive exchanges with their children. Studies have shown that a mindful approach to parenting can enhance a parent’s caregiving ability and self-awareness in the family unit.
Methods: A pretest/posttest study evaluated the effectiveness of a 6-week mindful parenting program. Four parents of adolescents with executive function deficits participated …
Women Family Members’ Experiences Of Involvement In Adult Inpatient Traumatic Brain Injury Rehabilitation, Isabelle Savage, Mary Egan
Women Family Members’ Experiences Of Involvement In Adult Inpatient Traumatic Brain Injury Rehabilitation, Isabelle Savage, Mary Egan
The Open Journal of Occupational Therapy
Background: Traumatic Brain Injury (TBI) rehabilitation is an intensive process aimed at reducing disability. The experience of care is lived not only by the patient with TBI, but by the family as well.
Methods: Five women family members of patients with TBI were interviewed. Based on a descriptive qualitative approach informed by phenomenology, thematic analysis was completed to draw a general sense of family members’ description of their involvement.
Results: Two themes were identified: Wearing different hats and a balancing act, that highlight the many roles undertaken by the women family members as well as the difficulties …
Journey Interrupted: A Phenomenological Exploration Of Miscarriage, Marit A. Watson, Vanessa D. Jewell, Sarah L. Smith
Journey Interrupted: A Phenomenological Exploration Of Miscarriage, Marit A. Watson, Vanessa D. Jewell, Sarah L. Smith
The Open Journal of Occupational Therapy
Background: Miscarriage is a significant life event that impacts occupational performance, identity, and competence and that influences perceptions of motherhood. Because of the lack of social rituals often attributed to the death of a loved one, miscarriages may result in disenfranchised grief, which impedes coping.
Methods: This phenomenological study explored the impact of miscarriage on relationships, perceptions of motherhood, and the meaning of occupation in the context of grief. Data was collected through semi-structured interviews (N = 4) and completion of a brief demographic questionnaire. The interviews were digitally recorded, transcribed verbatim, and reviewed to ensure accuracy. Using inductive thematic …
Considering Technology In The Occupational Therapy Practice Framework, Cara E. Masselink
Considering Technology In The Occupational Therapy Practice Framework, Cara E. Masselink
The Open Journal of Occupational Therapy
The Occupational Therapy Practice Framework, 3rd edition (2014), presents an incomplete infrastructure of assistive technology’s role in occupational therapy. Assistive technology and device use is currently defined in “Preparatory methods” (AOTA, 2014, p. S29); however, this categorization presents conflicting information to readers. This article aims to analyze assistive technology in the definition logic rules of precision and parsimony. The classification scheme will be assessed in the logic rules of exclusivity and exhaustiveness. The results of the analysis guide the placement of assistive technology in the profession’s guiding document. This may protect coverage and reimbursement, the education of clinicians, and best …
Ecological Momentary Assessment: Enriching Knowledge Of Occupation Using App-Based Research Methodology, Niki Kiepek
Ecological Momentary Assessment: Enriching Knowledge Of Occupation Using App-Based Research Methodology, Niki Kiepek
The Open Journal of Occupational Therapy
This paper introduces occupational therapists to ecological momentary assessment (EMA) and outlines factors that guide the process of designing a project. EMA methodology is a research methodology that uses electronic devices and specially designed software, or Apps, to collect real-time data. This methodology may enhance the ecological validity of research by collecting data about daily occupations in situated contexts. EMA data collection provides access to highly detailed and specific data and has the potential to reveal longitudinal patterns of change over a short period of time. It is valued as a means to examine events, precursors, and consequences. EMA methodology …
The Impact Of Online Video Cases On Clinical Reasoning In Occupational Therapy Education: A Quantitative Analysis, Lynne F. Murphy, Wendy B. Stav
The Impact Of Online Video Cases On Clinical Reasoning In Occupational Therapy Education: A Quantitative Analysis, Lynne F. Murphy, Wendy B. Stav
The Open Journal of Occupational Therapy
Clinical reasoning, the cognitive process of a skilled occupational therapist, is a complex and necessary component of evaluating clients and implementing interventions that facilitate each client’s achievement of relevant and meaningful participation in daily occupations. Clinical reasoning encompasses a set of skills that must be integrated into college curricula for the preparation of occupational therapists, but it is not easily taught in a classroom setting. This quasi-experimental, quantitative research explored how specific instructional techniques, constructed on the tenets of case-based reasoning, influenced the development of clinical reasoning in occupational therapy students. The experimental group with video cases improved significantly in …
Perceptions Of Older Adults On The Use Of An Interactive Video Game In Promoting Health And Well-Being, Maria Cruz, Julie D. Kugel, Liane Hewitt, Arezou Salamat
Perceptions Of Older Adults On The Use Of An Interactive Video Game In Promoting Health And Well-Being, Maria Cruz, Julie D. Kugel, Liane Hewitt, Arezou Salamat
The Open Journal of Occupational Therapy
Background: This study explored the perceptions of older adults on the use of a custom built interactive video game (IVG) in promoting health and well-being among the older adult population.
Method: This qualitative study used a phenomenological approach and enrolled 10 older adults over the age of 65 years in a client-centered, custom-built interactive video game program. This program was designed to promote activity tolerance, balance, range of motion, cognitive skills, and enjoyment through physical activity. The participants completed up to 12 Coin Catcher IVG sessions over a 4-week period. A postprogram, semi-structured, and audio-recorded interview explored their perceptions and …
They Said: A Global Perspective On Access To Assistive Technology, Angela K. Boisselle, Lenin C. Grajo
They Said: A Global Perspective On Access To Assistive Technology, Angela K. Boisselle, Lenin C. Grajo
The Open Journal of Occupational Therapy
International experts in assistive technology from five global regions (South America, Asia Pacific, Europe, Africa, and Australia) and with affiliation to the World Health Organization (WHO) Global Cooperation on Assistive Technology (GATE) community were invited to share their perspectives on the delivery of assistive technology and provision of assistive products in their regions. Four common topics emerged from the experts: (a) user and environmental barriers; (b) policy, funding, and product access; (c) professional training, collaboration, and service delivery; and (d) occupational justice (i.e., empowerment, participation, and progress).
Infusing An Occupational Justice Perspective To Technology Use In Occupational Therapy Practice, Lenin C. Grajo, Angela K. Boisselle
Infusing An Occupational Justice Perspective To Technology Use In Occupational Therapy Practice, Lenin C. Grajo, Angela K. Boisselle
The Open Journal of Occupational Therapy
Vital to building best and evidence-based practices in technology use in occupational therapy is the understanding of technology access, the lived experience of clients from diverse backgrounds who use technologies every day, and the understanding of many various factors (e.g., socioeconomic, political, geographical) that may influence the use of and access to technology. In this Letter from the Editors, we want to infuse the notion of occupational justice in the way that we, occupational therapy practitioners, understand and assess the impact of technology use in daily occupational participation.
Tanapox: A Potential Oncolytic Virus For The Treatment Of Cancer, Joel Marty
Tanapox: A Potential Oncolytic Virus For The Treatment Of Cancer, Joel Marty
Honors Theses
The National Cancer Institute defines cancer as a group of related diseases characterized by unimpeded cell division with metastatic abilities. Cells frequently mutate and potentially become cancerous, but generally these cells are cleared by the immune system. The disease state of cancer arises when the mutated cells evade the immune clearance, which indicates medical intervention is required. Current therapies most commonly utilize chemotherapy, radiation, or a combination of the two, however, alternative therapies are being developed such as immunotherapies and oncolytic viruses (OVs). OVs cause a viral infection, clearing cancerous cells through viral replication mechanisms, such as viral cytolysis, while …