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Articles 2911 - 2940 of 4358

Full-Text Articles in Medicine and Health Sciences

Examining The Influence And Role Of Pharmacogenetics Among Children With Autism Spectrum Disorder, Nuha Shaker Jul 2017

Examining The Influence And Role Of Pharmacogenetics Among Children With Autism Spectrum Disorder, Nuha Shaker

Masters Theses & Specialist Projects

Pharmacogenetics is the study of genomic-guided individualized drug prescription that plays an important role in preventing the severe adverse effects of drugs, decreasing the time and cost of therapeutic choices, and directing healthcare professionals to choose medications that are effective and safe. It is noteworthy that this approach becomes highly beneficial in patients suffering from chronic diseases or disorders, since these conditions may require multiple and long term pharmacological therapies, as in children with autism spectrum disorder (ASD). However, public acceptance is a major challenge when implementation of pharmacogenetics merges into clinical practice. The purpose of this study is a) …


Consumer Knowledge, Perception And Attitudes Of Unlabeled Genetically Modified Foods Of An Educated Population In The State Of Kentucky, Aldious A. Waite Jul 2017

Consumer Knowledge, Perception And Attitudes Of Unlabeled Genetically Modified Foods Of An Educated Population In The State Of Kentucky, Aldious A. Waite

Masters Theses & Specialist Projects

Genetically modified (GM) foods technology is a novel idea for improving food and crop production, but the supposed health risk of GM foods, such as possible negative long-term health effects to humans, animals and the environment, have provoked the European Union to create assessment protocols to monitor and regulate the safety of GM foods and crops. This research investigates the perception and attitudes of unlabeled GM foods of the WKU faculty and staff. A survey was administered via WKU Qualtrics, and chi-square tests were performed to see how the benefits and disadvantages of GM foods may affect the purchasing decisions …


Numerically Solving A System Of Pdes Modeling Chronic Wounds Treated With Oxygen Therapy, Stefan Stryker Jun 2017

Numerically Solving A System Of Pdes Modeling Chronic Wounds Treated With Oxygen Therapy, Stefan Stryker

Mahurin Honors College Capstone Experience/Thesis Projects

Chronic wounds such as diabetic foot ulcers are the leading cause of non-traumatic amputations in developed countries. For researchers to better understand the physiology of these wounds, a mathematical model describing oxygen levels at the wound site can be used to help predict healing responses. The model utilizes equations that are modified from work by Guffey (2015) that consists of four variables – oxygen, bacteria, neutrophils, and chemoattractant within a system of partial differential equations. Our research focuses on numerically solving these partial differential equations using a finite volume approach. This numerical solver will be important for future research in …


The Validity Of Submaximal Exercise Testing In Obese Women, Gabrielle Ringenberg Jun 2017

The Validity Of Submaximal Exercise Testing In Obese Women, Gabrielle Ringenberg

Mahurin Honors College Capstone Experience/Thesis Projects

Background: Submaximal exercise tests use heart rate responses to low-to-moderate intensity activity in order to predict cardiorespiratory fitness (VO2max). Currently used tests may be inappropriate for obese populations as obese women have altered heart rate responses to exercise. The purpose of this project is to test the validity of the Modified Bruce Protocol submaximal treadmill test in obese women. Methods: Normal-weight (NWG) and obese women (OBG) completed the Modified Bruce submaximal treadmill test (to predict VO2max using previously validated equations) and a maximal graded exercise test on a treadmill using the Standard Bruce Protocol (to obtain an …


Cytotoxicity Of Platinum Anticancer Drugs In Mammalian Cell Lines Of Metastatic Cancer, Hosannah Evie Jun 2017

Cytotoxicity Of Platinum Anticancer Drugs In Mammalian Cell Lines Of Metastatic Cancer, Hosannah Evie

Mahurin Honors College Capstone Experience/Thesis Projects

With the invention of advanced technology, focus has been put on understanding and looking for potential cures for many diseases, one of which is cancer. The difference in the leaving and non-leaving ligands of the FDA approved cancer drugs contributes to the differential cell specific cytotoxic effects. These drugs such as oxaliplatin approved for colorectal cancer, cisplatin approved for testicular cancer, and their analogs were used to treat different cancer cell lines in an MTT assay. This project aims to determine how changing the molecular shape of these compounds affects their uptake and toxicity into different cell lines. The assay …


Nutritional And Behavioral Repercussions Of Food Insecurity And The Impact Of Nutrition Education, Kelly Burgess Jun 2017

Nutritional And Behavioral Repercussions Of Food Insecurity And The Impact Of Nutrition Education, Kelly Burgess

Mahurin Honors College Capstone Experience/Thesis Projects

Food insecurity occurs when an individual does not have consistent access to fresh, nutritious food in safe, socially acceptable, and affordable ways. This is a significant challenge facing Kentuckians, with one in six adults and one in four children experiencing some degree of food insecurity. The present study examines the effectiveness of customized nutrition education in improving 1) nutrition-related behaviors associated with food insecurity and 2) management of household food supply in food-insecure individuals with and without children. Participants were recruited through HOTEL INC, and one was from a household without children and one with children. A pre-assessment survey evaluated …


Intergenerational Living Between College Students And Senior Housing Residents: A Framework, Laura Allen Jun 2017

Intergenerational Living Between College Students And Senior Housing Residents: A Framework, Laura Allen

Mahurin Honors College Capstone Experience/Thesis Projects

Ageism, the discrimination against persons of a certain age group, is one of the most important civil rights issues of the 21st century (Palmore, 2015). There are community-wide and personal strategies to combatting ageism. Homesharing and cohousing each offer concepts that can be utilized in intergenerational living because of their housing infrastructure. The relationship between college students and senior housing residents is unique because both groups are experiencing a season of life with common characteristics. This project aims to understand the relationship and tensions between stakeholders of existing intergenerational living programs to develop an implementation plan for a program at …


Investigating The Synergistic Effects Of Cisplatin And Two Curcuminoid Compounds On Cancer, Denis Hodzic Jun 2017

Investigating The Synergistic Effects Of Cisplatin And Two Curcuminoid Compounds On Cancer, Denis Hodzic

Mahurin Honors College Capstone Experience/Thesis Projects

Cisplatin is an anti-cancer drug effective against several cancers which can produce the serious side-effect of hearing loss. Curcumin, a natural plant compound, can increase the activity of cisplatin against cancer and counteract cisplatin’s effect against hearing. Because curcumin exhibits poor bioavailability, there is considerable interest in developing synthetic curcumin analogs (curcuminoids) that are more soluble and which retain anti-cancer activity and otoprotective function. This study investigated whether two curcuminoids, EF-24 and CLEFMA, increase the cytotoxic and ototoxic effects of cisplatin against the lung cancer cell line, A549, and the colorectal cancer cell line, Caco2. Cytotoxicity was measured by using …


Assessment Of Endpoint Criteria And Perceived Barriers During Maximal Cardiorespiratory Testing Among Pregnant Women, Caitlin Hesse Jun 2017

Assessment Of Endpoint Criteria And Perceived Barriers During Maximal Cardiorespiratory Testing Among Pregnant Women, Caitlin Hesse

Mahurin Honors College Capstone Experience/Thesis Projects

PURPOSE: Plateau in oxygen consumption (VO2) is the primary indicator for determining if an individual has reached their true maximal aerobic capacity (Howley et al., 1995). Although age and gender-specific secondary criteria (i.e. additional criteria that can be used to identify one’s attainment of maximal effort) have been developed for the healthy population, no secondary criteria have been established for pregnant women (Edvarsen et al., 2014). The primary purpose of this study was to analyze secondary endpoint criteria during VO2max testing among pregnant women during the 2nd trimester. A secondary purpose was to identify emotional and physical …


Ua61/16 Pre-Commencement Hooding & Awards Ceremony, Wku Physical Therapy May 2017

Ua61/16 Pre-Commencement Hooding & Awards Ceremony, Wku Physical Therapy

WKU Administration Documents

Pre-commencement program for WKU Physical Therapy class of 2017.


The Validity Of Apple Watch For Energy Expenditure Estimation In Physical Activity, P. Zhang, C. Witmer, S. Godin, D. Che, M. Owens, A. Hanna, T. Casey, R. Finnegan, C. Niewojt May 2017

The Validity Of Apple Watch For Energy Expenditure Estimation In Physical Activity, P. Zhang, C. Witmer, S. Godin, D. Che, M. Owens, A. Hanna, T. Casey, R. Finnegan, C. Niewojt

International Journal of Exercise Science: Conference Proceedings

Please see the pdf version of the abstract.


The Inter-Rater Reliability Of A-Mode Ultrasound For Determining Percent Body Fat Among College-Aged Males, C. Woelkers, P. Cutrufello, M. Landram, N. Capobianco May 2017

The Inter-Rater Reliability Of A-Mode Ultrasound For Determining Percent Body Fat Among College-Aged Males, C. Woelkers, P. Cutrufello, M. Landram, N. Capobianco

International Journal of Exercise Science: Conference Proceedings

Please see the pdf version of the abstract.


Development Of A Computational Tool For Optimal Resting Metabolic Rate Calculation, J. Zhang, M. Darnell, B. Nindl, Q. Mi May 2017

Development Of A Computational Tool For Optimal Resting Metabolic Rate Calculation, J. Zhang, M. Darnell, B. Nindl, Q. Mi

International Journal of Exercise Science: Conference Proceedings

Please see the pdf version of the abstract.


Exercise Reduces High-Fat Diet Induced Colon Inflammation But Does Not Influence Muc2 Expression, P. Wisniewski Ii, L. Joseph, G. Composto, S. Lightfoot, S. Campbell May 2017

Exercise Reduces High-Fat Diet Induced Colon Inflammation But Does Not Influence Muc2 Expression, P. Wisniewski Ii, L. Joseph, G. Composto, S. Lightfoot, S. Campbell

International Journal of Exercise Science: Conference Proceedings

Please see the pdf version of the abstract.


Effects Of A 4-Week Fitness Intervention On Vascular Health And Fitness In Firefighters Vs Non-Firefighters, T. Wisdo, A. Getty, L. Chavis, S. Close, C. Derella, W. Dicurcio, R. Jasinski, K. Mclaughlin, A. Perez, M. Corbin, A. Polimeni, J. Hill, D. Feairheller May 2017

Effects Of A 4-Week Fitness Intervention On Vascular Health And Fitness In Firefighters Vs Non-Firefighters, T. Wisdo, A. Getty, L. Chavis, S. Close, C. Derella, W. Dicurcio, R. Jasinski, K. Mclaughlin, A. Perez, M. Corbin, A. Polimeni, J. Hill, D. Feairheller

International Journal of Exercise Science: Conference Proceedings

Please see the pdf version of the abstract.


Atrophy Of Muscle Cells Results In A Selective Packaging Of Proteins Into Exosomes, B. Wilson, C. Pautz, C. Barrero, J. Selsby, E. Kelly, M. Hudson May 2017

Atrophy Of Muscle Cells Results In A Selective Packaging Of Proteins Into Exosomes, B. Wilson, C. Pautz, C. Barrero, J. Selsby, E. Kelly, M. Hudson

International Journal of Exercise Science: Conference Proceedings

Please see the pdf version of the abstract.


"Expert" Advice On Dietary Supplements, T. Wikert, K. Kletzli, A. Rickman, J. Lynn May 2017

"Expert" Advice On Dietary Supplements, T. Wikert, K. Kletzli, A. Rickman, J. Lynn

International Journal of Exercise Science: Conference Proceedings

Please see the pdf version of the abstract.


Minimalist Footwear Reduces Muscle Activity In The Lower Leg During A Jump Landing Task, P. Whitehead, M. Tammaro, J. Schmitz, M. Darnell May 2017

Minimalist Footwear Reduces Muscle Activity In The Lower Leg During A Jump Landing Task, P. Whitehead, M. Tammaro, J. Schmitz, M. Darnell

International Journal of Exercise Science: Conference Proceedings

Please see the pdf version of the abstract.


Time-Dependent Effects Of Acute Cycling Exercise On Long-Term Emotional Memory And Salivary A-Amylase, L. Weiss, A. Venezia, C. Smith May 2017

Time-Dependent Effects Of Acute Cycling Exercise On Long-Term Emotional Memory And Salivary A-Amylase, L. Weiss, A. Venezia, C. Smith

International Journal of Exercise Science: Conference Proceedings

Please see the pdf version of the abstract.


Blood Pressure Cuff Selection: Does One Size Fit All?, M. Walsh, T. Kuhn, J. Mcfadden, T. Weeter, M. Holmstrup, B. Jensen May 2017

Blood Pressure Cuff Selection: Does One Size Fit All?, M. Walsh, T. Kuhn, J. Mcfadden, T. Weeter, M. Holmstrup, B. Jensen

International Journal of Exercise Science: Conference Proceedings

Please see the pdf version of the abstract.


Reliability Of Identifying Emg Onset Of Complex Human Movement Electromyography Signals, V. Voorhees, A. Fong, D. Drill, D. King, M. Tenan May 2017

Reliability Of Identifying Emg Onset Of Complex Human Movement Electromyography Signals, V. Voorhees, A. Fong, D. Drill, D. King, M. Tenan

International Journal of Exercise Science: Conference Proceedings

Please see the pdf version of the abstract.


Effects Of Exercise And Exogenous Glucose On Short-Term Memory Recall In Young Adults, L. Vanhorn, S. Szilagyi, S. Haase, W. Braun May 2017

Effects Of Exercise And Exogenous Glucose On Short-Term Memory Recall In Young Adults, L. Vanhorn, S. Szilagyi, S. Haase, W. Braun

International Journal of Exercise Science: Conference Proceedings

Please see the pdf version of the abstract.


Comparison Of Metabolic Rate Between Concentric And Eccentric Muscle Actions, Z. Valenti, S. Guarnera, N. Carlini, W. Fountain, T. Heinbockel, C. Lynch, B. Meister, I. Matthews, C. Raley, S. Mazzetti May 2017

Comparison Of Metabolic Rate Between Concentric And Eccentric Muscle Actions, Z. Valenti, S. Guarnera, N. Carlini, W. Fountain, T. Heinbockel, C. Lynch, B. Meister, I. Matthews, C. Raley, S. Mazzetti

International Journal of Exercise Science: Conference Proceedings

Please see the pdf version of the abstract.


Habitual Users Of Minimalist Footwear Display Better Dynamic Postural Stability During A Jump Landing Task, M. Tammaro, J. Schmitz, M. Darnell, P. Whitehead May 2017

Habitual Users Of Minimalist Footwear Display Better Dynamic Postural Stability During A Jump Landing Task, M. Tammaro, J. Schmitz, M. Darnell, P. Whitehead

International Journal of Exercise Science: Conference Proceedings

Please see the pdf version of the abstract.


Ambulatory Blood Pressure And Habitual Physical Activity In Chronic Kidney Disease, K. Suresh, D. Kirkman, B. Muth, J. Stock, D. Edwards May 2017

Ambulatory Blood Pressure And Habitual Physical Activity In Chronic Kidney Disease, K. Suresh, D. Kirkman, B. Muth, J. Stock, D. Edwards

International Journal of Exercise Science: Conference Proceedings

Please see the pdf version of the abstract.


Photo-Plethysmography Heart Rate And Activity Measures During Exercise, J. Stock, M. Botieri, R. Pohlig, D. Edwards, G. Dominick May 2017

Photo-Plethysmography Heart Rate And Activity Measures During Exercise, J. Stock, M. Botieri, R. Pohlig, D. Edwards, G. Dominick

International Journal of Exercise Science: Conference Proceedings

Please see the pdf version of the abstract.


Caffeine Withdrawal And Acute Consumption Effects On Reaction Time And Muscular Strength, Power, And Endurance, K. Sprow, G. Hudson, T. Hannings, L. Dipietro May 2017

Caffeine Withdrawal And Acute Consumption Effects On Reaction Time And Muscular Strength, Power, And Endurance, K. Sprow, G. Hudson, T. Hannings, L. Dipietro

International Journal of Exercise Science: Conference Proceedings

Please see the pdf version of the abstract.


The Effects Of Multiple Sets Of Squats And Jump Squats On Mechanical Variables, B. Snyder, M. Rossetti, G. Moir, S. Munford, S. Davis May 2017

The Effects Of Multiple Sets Of Squats And Jump Squats On Mechanical Variables, B. Snyder, M. Rossetti, G. Moir, S. Munford, S. Davis

International Journal of Exercise Science: Conference Proceedings

Please see the pdf version of the abstract.


Evaluating The Relationship Between Vertical Jump Performance And Fms In Young Adult Males, A. Smith, A. Bosak, C. Carver, M. Sokoloski, J. Houck, J. Feister, R. Sanders May 2017

Evaluating The Relationship Between Vertical Jump Performance And Fms In Young Adult Males, A. Smith, A. Bosak, C. Carver, M. Sokoloski, J. Houck, J. Feister, R. Sanders

International Journal of Exercise Science: Conference Proceedings

Please see the pdf version of the abstract.


Relationships Between Mobility Tests And Maximum Bicycling Cadence During Speed Training In Older Adults, B. Sibson, M. Bellumori, C. Knight May 2017

Relationships Between Mobility Tests And Maximum Bicycling Cadence During Speed Training In Older Adults, B. Sibson, M. Bellumori, C. Knight

International Journal of Exercise Science: Conference Proceedings

Please see the pdf version of the abstract.