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Articles 3121 - 3150 of 5384

Full-Text Articles in Medicine and Health Sciences

Expression Profiling And Functional Validation Of Micrornas Involved In Schizophrenia And Bipolar Disorder, Albert H. Kim Jul 2011

Expression Profiling And Functional Validation Of Micrornas Involved In Schizophrenia And Bipolar Disorder, Albert H. Kim

Theses and Dissertations

MicroRNAs (miRNAs) are a family of small non-coding RNAs that regulate gene expression at both the mRNA and protein levels. MiRNAs have been shown to affect neuronal differentiation, synaptosomal complex localization and synapse plasticity, all functions thought to be disrupted in schizophrenia. We investigated the expression of 667 miRNAs (miRBase v.13) in the prefrontal cortex of individuals with schizophrenia (SZ, N = 35) and bipolar disorder (BP, N =35) using a real-time PCR-based Taqman Low Density Array (TLDA). After extensive QC steps, 441 miRNAs were included in the final analyses. At a FDR of 10%, 22 miRNAs were identified as …

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Natural Disasters And Older Adults: The Social Construction Of Disaster Planning, Elizabeth Fugate-Whitlock Jul 2011

Natural Disasters And Older Adults: The Social Construction Of Disaster Planning, Elizabeth Fugate-Whitlock

Theses and Dissertations

Examining older adults’ experiences with and response toward hurricanes within the context of the community of residence is key to both understanding their experiences and planning for future hurricanes. Specific to this research, the objective was to understand the current social network of older adults, or who provides care for whom under what circumstances, using the social constructionist perspective. Grounded theory combined with action research was the theoretical orientation guiding the study. Sources of data included the collection of household disaster plans, semi-structured interviews with older adult residents of housing authority neighborhoods, semi-structured interviews with community planners, and observation of …

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Analysis Of The Role Of Outer Surface Protein C (Ospc) In Borrelia Burgdorferi Pathogenesis, Delacy Rhodes Jul 2011

Analysis Of The Role Of Outer Surface Protein C (Ospc) In Borrelia Burgdorferi Pathogenesis, Delacy Rhodes

Theses and Dissertations

Lyme disease is an emerging infection that is caused by the Borrelia burgdorferi sensu lato complex. These bacteria exist in nature through an enzootic life cycle involving Ixodes ticks and various reservoir hosts. One way that this bacterium adapts to the different hosts in the enzootic cycle is through the expression of outer surface protein C (OspC). OspC is a surface exposed lipoprotein encoded on circular plasmid 26 that forms homodimers on the bacterial surface and has distinct conserved and variable portions of sequence. When ospC is deleted, the spirochetes are unable to cause mammalian infection although the mechanism of …

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Quantifying Polypharmacy In Diabetes Patients In The U.S., Jing Tao Jul 2011

Quantifying Polypharmacy In Diabetes Patients In The U.S., Jing Tao

Theses and Dissertations

ix Objectives: To quantify polypharmacy and assess the socio-economic predictors of medication use and expenditure in diabetics. Methods: This study analyzed adult diabetes patients using a nationally representative sample in Medical Expenditure Panel Survey in 2006. Top ten most highly utilized drug classes were identified. Descriptive statistics were used to portray the patients’ medication utilization and spending. Generalized linear models were conducted to assess the socio-economic variants in drug use and spending. Results: On average, a diabetes patient had 45 prescriptions in 2006, for total annual spending of $3,161. A diabetes patient used drugs from 3.43 classes within top ten …

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Helper Phage Capsid Size Redirection By Staphylococcal Pathogenicity Island Sapi1 Involves Internal Scaffolding Proteins., Priyadarshan Damle Jul 2011

Helper Phage Capsid Size Redirection By Staphylococcal Pathogenicity Island Sapi1 Involves Internal Scaffolding Proteins., Priyadarshan Damle

Theses and Dissertations

Staphylococcus aureus is one of the leading causes of nosocomial and community acquired infections. Many of the virulence factors are encoded on staphylococcal mobile genetic elements. Members of the SaPI family of S. aureus mobile elements encode superantigens and are mobilized at high frequency by specific helper bacteriophages. One remarkable feature of helper phage exploitation by SaPIs is remodeling of the normal T=7 bacteriophage capsid to produce smaller T=4 phage-like particles. These particles, composed entirely of helper phage proteins, can accommodate the smaller SaPI genome while excluding that of a complete helper phage. This study was designed to understand the …

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Development And Evaluation Of A Multiplex Suspension Array Protocol For The Detection Of Enteric Pathogens From Clinical Specimens, Carol Walters Jul 2011

Development And Evaluation Of A Multiplex Suspension Array Protocol For The Detection Of Enteric Pathogens From Clinical Specimens, Carol Walters

Theses and Dissertations

Foodborne illnesses are a significant public health challenge in the United States, with an estimated 9.4 million illnesses annually attributed to the consumption of contaminated food, of which 59% are estimated to be caused by viruses, 39% by bacteria and 2% by parasites. Timely detection and identification of the pathogens causing foodborne outbreaks is vital for the implementation of outbreak control strategies, allowing public health officials to prevent additional illnesses and maintain confidence in the food supply. Public health laboratories employ a variety of traditional and molecular testing techniques to identify foodborne outbreak etiologic agents. One technology is the Luminex …

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Intracellular Signaling Contributions To Behaviors Relevant To Nicotine Addiction, Lauren Thompson Jul 2011

Intracellular Signaling Contributions To Behaviors Relevant To Nicotine Addiction, Lauren Thompson

Theses and Dissertations

Nicotine is the primary addictive substance in tobacco, and most smokers who quit will relapse within a year. Evidence shows that cigarette craving increases over time, termed “incubation.” The purpose of these studies was to see if protracted abstinence from chronic nicotine increases rat self-administration, an animal model with good face validity for human tobacco use, and if nicotine self-administration during daily exposure/after 8+ days of abstinence is regulated by extracellular signal-regulated kinase (ERK) signaling in the nucleus accumbens (NAc) shell or anterior cingulate cortex (PFC). ERK kinase inhibitor U0126 was infused in the NAc shell or PFC of Long …

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Analysis And Fingerprinting Of Glycosaminoglycans, Joseph King Jul 2011

Analysis And Fingerprinting Of Glycosaminoglycans, Joseph King

Theses and Dissertations

Heparin is a complex mixture of sulfated polysaccharides derived from animals and one of the oldest drugs in use. While an efficacious anticoagulant, heparin is beset by side effects and pharmacokinetic difficulties. Low molecular weight heparins (LMWH) are made by depolymerizing unfractionated heparin (UFH) and present improvements in these areas. However, they still retain a phenomenally high level of complexity due to their polydispersity and the introduction of non-native structural features. This makes the structural characterization LMWHs a daunting task. This work details the development of a novel capillary electrophoretic (CE) method for fingerprinting LMWHs. Since their complexity normally results …

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Racial Differences In The Genetics Of Preeclampsia, Lori Hill Jul 2011

Racial Differences In The Genetics Of Preeclampsia, Lori Hill

Theses and Dissertations

Preeclampsia (PE), characterized by hypertension and proteinuria after 20 weeks of gestation, affects 5-8% of pregnancies worldwide. Although preeclampsia is a significant cause of maternal and perinatal mortality and morbidity, its etiology remains to be elucidated. Racial differences have been observed for preeclampsia, with U.S. Blacks having higher rates and more severe disease, compared to U.S. Whites and Hispanics. One potential source of racial differences in preeclampsia is genetic variation between populations. Genetic susceptibility to preeclampsia is well established, but the specific contributions of maternal vs. fetal genes, and how these vary among racial groups is poorly understood. This dissertation …

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Sythesis And Biological Screening Of A Series Of Novel Chemokine Receptor Ccr5 Antagonists, Soundarya Vaithianathan Jul 2011

Sythesis And Biological Screening Of A Series Of Novel Chemokine Receptor Ccr5 Antagonists, Soundarya Vaithianathan

Theses and Dissertations

The chemokine receptor CCR5 has been implicated in the pathogenesis of cancers and AIDS. A series of novel piperidine derivatives were designed, synthesized, and evaluated as CCR5 antagonists. The ability of the new ligands to inhibit the increment of intracellular calcium level stimulated by endogenous ligand CCL5 was measured in the calcium mobilization assay as an indication of its CCR5 receptor antagonism. The anti-proliferation assay was performed to measure the ability of these new compounds to inhibit the proliferation of prostate cancer cell lines, PC-3 and M12. A new lead compound has been identified which showed micromolar level of inhibition …

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Synthesis Of A Library Of Sulfated Small Molecules, Shrenik Mehta Jul 2011

Synthesis Of A Library Of Sulfated Small Molecules, Shrenik Mehta

Theses and Dissertations

The discovery of heparin in 1916 resulted in a huge impact on the practice of medicine. Heparin has played a major role in alleviating thrombotic disorders and has also exhibited effects on almost every major system in the human body. Over the past few decades, more and more heparin-protein interactions have come to light. It is implicated to modulate several important processes such as cell growth and differentiation, inflammatory response, viral infection mechanism etc. More interesting is the observation that these interactions are considerably specific with regard to oligosaccharide sequences which have specific spatially oriented sulfate groups modulating the responses. …

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Assessing The Role Of Polyethylene Glycol (Peg) In Improving Functional Recovery Following Spinal Cord Injury, Dustin Dalton Jul 2011

Assessing The Role Of Polyethylene Glycol (Peg) In Improving Functional Recovery Following Spinal Cord Injury, Dustin Dalton

Theses and Dissertations

Injury to the spinal cord results in the disruption of signal transmission between the brain and distal targets. It often presents with the loss of motor function and sensory perception below the level of injury. There are many obstacles following injury that must be overcome in order to encourage axon regeneration and improve functional recovery. A combinatorial approach is necessary to combat physical and chemical barriers to recovery. The fluid filled cyst that forms in the majority of spinal cord injuries presents a physical barrier that we treat with our electrospun bridges. We implanted our bridges into female Long Evans …

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Proteomic Analysis Of Two Different States Of Naegleria Fowleri, Hong Park Jul 2011

Proteomic Analysis Of Two Different States Of Naegleria Fowleri, Hong Park

Theses and Dissertations

Naegleria fowleri are free-living ameboflagellates found in soil and freshwater habitats throughout the world that cause a fatal disease in humans called Primary Amoebic Meningoencephalitis (PAM). Mechanisms of host resistance or susceptibility to infection have not been fully elucidated, and possible treatment methods are still sub optimal. The disease is diagnosed using specific laboratory tests available in only a few laboratories in the United States. Because of the rarity of infection and difficulty in initial detection, more than often PAM is misdiagnosed. Therefore, it is very important to find causative marker for early detection of an infection. The purpose of …

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Rural Hospital System Affiliations And Their Effects On Hospital Economic Performance, 2004-2008, Mark Swofford Jun 2011

Rural Hospital System Affiliations And Their Effects On Hospital Economic Performance, 2004-2008, Mark Swofford

Theses and Dissertations

The formation of multi-hospital systems represents one of the largest structural changes in the hospital industry. As of 2008, system affiliated hospitals outnumbered stand alone hospitals 2511 to 2167 and the percentage of system affiliated rural hospitals has increased dramatically from 24.8% in 1983 to 42.2% in 2008 (based on AHA data for non-federal acute care general hospitals). The effects of system membership on hospital performance have been of great interest to health care researchers, but the majority of research on multi-hospital systems has either focused exclusively on urban facilities or pooled urban and rural facilities in the same sample, …

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The Relationship Between Physicians‘ Ownership Of Physical Therapy Services And Referral Patterns To Hospital-Based Outpatient Rehabilitation Centers, Joy Bruce Jun 2011

The Relationship Between Physicians‘ Ownership Of Physical Therapy Services And Referral Patterns To Hospital-Based Outpatient Rehabilitation Centers, Joy Bruce

Theses and Dissertations

Background and Purpose A debate over the practice of physician self-referral has been ongoing in health care since the 1980s. At issue is the practice of physicians who refer patients to facilities in which they share a financial interest, a phenomenon known as referral for profit. Physician investment or ownership interest in ancillary (e.g., physical therapy) services has been shown to have an impact on utilization rates, costs, access to care, and quality of care. What has not been identified in previous research is the influence of physicians‘ selective referral on competing clinics, particularly the hospital-based outpatient centers that share …

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Differential Glial Cell Responses In The Dentate Gyrus In Young Adult And Aged Brains Following Traumatic Brain Injury, Christoher Shin Jun 2011

Differential Glial Cell Responses In The Dentate Gyrus In Young Adult And Aged Brains Following Traumatic Brain Injury, Christoher Shin

Theses and Dissertations

Traumatic brain injury (TBI) affects 3 out of every 1000 Americans each year, and is the leading cause of morbidity and mortality after trauma, accounting for as many as 56,000 deaths per year (Dutton and McCunn, 2003). The Centers for Disease and Control and Prevention found that TBI most commonly occurs in adolescents and young adults aged from 15 to 24 years and in the elderly (75 years and older). Following injury, the secondary injury begins almost immediately after the primary injury and is the result of a number of cascades where once activated, exacerbate the already altered homeostasis of …

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Cis 3,4', 5-Trimethoxy-3'-Aminostilbene (Stilbene 5c) Induces Apoptosis And Protective Autophagy In B16f10 Melanoma Cells, Betelehem Asnake Jun 2011

Cis 3,4', 5-Trimethoxy-3'-Aminostilbene (Stilbene 5c) Induces Apoptosis And Protective Autophagy In B16f10 Melanoma Cells, Betelehem Asnake

Theses and Dissertations

The weak selectivity of chemotherapeutic drugs against tumors has sustained efforts to develop better chemotherapeutic agents that are more potent and selective at destroying tumor cell populations versus normal tissues. This project focuses on evaluating the cell killing effects of the microtubule inhibitor, stilbene 5c, against melanoma cancer. We utilized an in vitro murine melanoma model to study the effects of stilbene 5c on tumor proliferation and survival, as well as growth arrest and cell death. Our findings indicate that stilbene 5c promotes dose dependent cell death in melanomas with the induction of apoptosis and autophagy. The role of autophagy …

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Three-Dimensional Photographic Evaluation Of Immediate Soft Tissue Changes Following Rapid Maxillary Expansion, Nathan Granillo Jun 2011

Three-Dimensional Photographic Evaluation Of Immediate Soft Tissue Changes Following Rapid Maxillary Expansion, Nathan Granillo

Theses and Dissertations

The skeletal and dental changes associated with rapid maxillary expansion (RME) are well documented. Effects on the soft tissues and the potential impact on facial esthetics have not been well researched. The purpose of this study was to evaluate immediate changes in facial soft tissues as a result of RME by comparing threedimensional digital photogrammetric images before and after RME treatment. The 3dMDface System was used to obtain photographic images of 21 patients (mean age = 11.8 years) before and after RME treatment for transverse maxillary deficiency. A control group of 13 patients (mean age = 12.7 years) also had …

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Self-Perception Of Smile Aesthetics And Self-Esteem, Larry Scarborough Jun 2011

Self-Perception Of Smile Aesthetics And Self-Esteem, Larry Scarborough

Theses and Dissertations

Introduction: Self-perception of smile aesthetics has been suggested as the most common reason for seeking orthodontic treatment. A recent study concluded that an improvement of dental attractiveness at the end of orthodontic treatment had positive effects on self-esteem. The purpose of this study was to determine if a relationship exists between one’s self-perceived smile aesthetics and their self-esteem. Methods: A survey was conducted where each subject completed an evaluation of their smile aesthetics and a Rosenberg Self-esteem Test (RST). A smiling photograph of each subject was evaluated by dental professionals for dental aesthetics and straightness. Results: Female students rated their …

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Cmv Vaccine Development Based On Epithelial Entry Mediators Ul128, Ul130, Ul131, Frances Saccoccio Jun 2011

Cmv Vaccine Development Based On Epithelial Entry Mediators Ul128, Ul130, Ul131, Frances Saccoccio

Theses and Dissertations

Congenital cytomegalovirus infection is the leading cause of sensorineural hearing loss in the U.S. CMV vaccines developed to date do not protect the majority of women of childbearing age from primary CMV infection. Insufficient vaccine-induced epithelial entry neutralizing activity may be the reason for poor performance of these vaccines. CMV entry into endothelial and epithelial but not fibroblast cells requires the virion envelope complex gH/gL/UL128-131. Since current vaccines do not target this complex, epithelial entry mediators UL128-131 are attractive subunit CMV vaccine candidates, since they should target mucosal immunity. The mucosal immune response, specifically salivary epithelial entry neutralizing activity, has …

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Heat Shock Proteins As Novel Cancer Therapeutics: Targeting The Hallmarks Of Cancer, Chao Li Jun 2011

Heat Shock Proteins As Novel Cancer Therapeutics: Targeting The Hallmarks Of Cancer, Chao Li

Theses and Dissertations

Molecular chaperones, commonly known as heat shock proteins (HSPs), are essential for mammalian cells to maintain homeostasis, and HSPs function by inducing an ATPase-coupled structural change, followed by interactions with diverse co-chaperones and over 200 client proteins implicated in many critical signaling networks. These highly expressed HSPs participate in the onset and progression of several human diseases including cancer, and their connection with tumorigenesis has facilitated research and clinical trials related to targeting HSPs as a novel anti-tumor therapy. The predominant mechanism of chaperone inhibition is through either disruption of the HSP association with client protein or an altered binding …

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Statistical Image Reconstruction For Quantitative Computed Tomography, Joshua Evans May 2011

Statistical Image Reconstruction For Quantitative Computed Tomography, Joshua Evans

Theses and Dissertations

Statistical iterative reconstruction (SIR) algorithms for x-ray computed tomography (CT) have the potential to reconstruct images with less noise and systematic error than the conventional filtered backprojection (FBP) algorithm. More accurate reconstruction algorithms are important for reducing imaging dose and for a wide range of quantitative CT applications. The work presented herein investigates some potential advantages of one such statistically motivated algorithm called Alternating Minimization (AM). A simulation study is used to compare the tradeoff between noise and resolution in images reconstructed with the AM and FBP algorithms. The AM algorithm is employed with an edge-preserving penalty function, which is …

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Impact Of Medicare Part D Coverage Gap On Beneficiaries' Adherence To Prescription Medications, Urvi Desai May 2011

Impact Of Medicare Part D Coverage Gap On Beneficiaries' Adherence To Prescription Medications, Urvi Desai

Theses and Dissertations

INTRODUCTION: Medicare Part D provides prescription drug coverage to seniors through a benefit plan with a major deductible inserted in the middle. It is important to study the extent to which this structure affects seniors’ adherence to prescription medications. Therefore, this study had the following objectives: (1) To identify characteristics of beneficiaries reaching and not reaching the coverage gap, (2) To study the entry and exit times from the coverage gap, (3) To study the impact of a complete gap in coverage on beneficiaries’ adherence to prescription medications, (4) To study the impact of a partial gap in coverage on …

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Application Of Pharmacometric Methods To Improve Pediatric Drug Development, Mallika Lala May 2011

Application Of Pharmacometric Methods To Improve Pediatric Drug Development, Mallika Lala

Theses and Dissertations

Pharmacometrics is a quantitative science that is rapidly changing the landscape of drug development, and particularly so for the pediatric population. The motivation behind the research underlying this dissertation is to contribute towards the improvement of pediatric drug development by the astute application of pharmacometric methods. Two distinct research areas have been focused upon: 1- improving pediatric pharmacokinetic (PK) trial design and 2- improving pediatric dosing of warfarin by using a genetics-based dosing regimen. The first project examined in detail the feasibility of and simulation-based methodology for implementing a recent regulatory PK quality standard. The focus was on designing pediatric …

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Prenatal Alcohol Exposure Reduces Dendritic Spine Density Across Sensory Cortices, Francis Oppong May 2011

Prenatal Alcohol Exposure Reduces Dendritic Spine Density Across Sensory Cortices, Francis Oppong

Theses and Dissertations

Dendritic spines are the major site of excitatory synapses in cortex, and factors that reduce dendritic spine numbers will produce serious cortical processing deficits, such as has been demonstrated for mental retardation and other psychiatric disorders. Prenatal alcohol exposure also has detrimental effects on brain development that lead to Fetal Alcohol Spectrum Disorder (FASD), which results in reduction of dendritic spine numbers in the hippocampus, prefrontal cortex and somatosensory cortex. FASD also is associated with temporal processing disorders involving sequential auditory stimuli that would be processed in auditory cortical areas. However, it is unknown if the reduction of spine density …

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Comparison Of Adhesion Of Gutta Percha/Ah Plus® And Resilon/Epiphany® Se™ After A Final Rinse With Different Concentrations Of Ethanol, Suren Paravyan May 2011

Comparison Of Adhesion Of Gutta Percha/Ah Plus® And Resilon/Epiphany® Se™ After A Final Rinse With Different Concentrations Of Ethanol, Suren Paravyan

Theses and Dissertations

The purpose of this study was to evaluate effect of final rinse of ethanol on bond strength in teeth obturated with Gutta Percha (GP)/AH Plus® or Resilon/Epiphany®SE™. Thirty-two extracted human anterior teeth were shaped to size 30, 0.06 taper and subjected to an identical irrigation protocol. Specimens were randomly divided into eight groups according to final irrigating solution (saline, 70%, 95%, 100% ethanol) and obturation material. Two millimeter thick slices were obtained by sectioning each obturated root. Bond strength was determined using micropush-out assay. Data was analyzed using Student’s t-test. Obturation with GP/AH Plus® formed a statistically significant stronger bond …

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The Effect Of Insulating K-Type Files On Accuracy And Reliability As Used In Two Electronic Apex Locators, Timothy Finkler May 2011

The Effect Of Insulating K-Type Files On Accuracy And Reliability As Used In Two Electronic Apex Locators, Timothy Finkler

Theses and Dissertations

The purpose of this in-vitro study is to compare the accuracy and reliability of a 3rd and 4th generation electronic apex locator (EAL) in locating the apical foramen when using insulated and non-insulated K files. Forty extracted human adult single-rooted teeth were coronally sectioned and placed in agar. EAL determined tooth length measurements were compared to actual tooth measurements. Comparisons to the standard measures used correlation and paired t-test. Preliminary comparisons of the groups used ANOVA to compare the means and the Brown-Forsythe test to compare variance. In the final analyses, the measurements were compared using a repeated-measures mixed-model multiway …

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Comparison Of Epiphany® And Ah-Plus® Root Canal Sealer Penetration Of Dentinal Tubules: A Sem Study, Kalisha Jordan May 2011

Comparison Of Epiphany® And Ah-Plus® Root Canal Sealer Penetration Of Dentinal Tubules: A Sem Study, Kalisha Jordan

Theses and Dissertations

The purpose of this study was to evaluate the effect of a final rinse of ethanol on depth of sealer penetration in teeth obturated with Gutta Percha (GP)/AH-Plus® (Dentsply, De Trey GmbH, Konstanz, Germany) or Resilon/Epiphany® SE™ (Pentron Clinical Technologies, LLC, Wallingford, CT). Extracted human anterior teeth (n= 32) were shaped to size 30, 0.06 taper using nickel-titanium rotary files and subjected to an identical irrigation protocol. Specimens were randomly divided into eight groups according to final irrigating solution (saline, 70%, 95%, or 100% ethanol) and obturation material (GP/AH-Plus® or Resilon/EpiphanyÒ SE™). A 2mm thick slice was obtained by sectioning …

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The Effects Of A Fluoride Releasing Orthodontic Primer On Demineralization Around Brackets: An In-Vivo Study., Daniel Pennella May 2011

The Effects Of A Fluoride Releasing Orthodontic Primer On Demineralization Around Brackets: An In-Vivo Study., Daniel Pennella

Theses and Dissertations

The purpose of this study was to investigate the effects of a fluoride releasing orthodontic primer on demineralization adjacent to brackets. Twenty-two patients were recruited for this study. One premolar was randomly chosen as the experimental tooth, the contralateral tooth was the control. Teeth were visually analyzed for white spot lesions (WSLs). Knoop microhardness was used to determine hardness. Visual examination results showed no significant difference in the number of WSLs observed between Opal Seal and Transbond XT over the duration of this study. Solid conclusions could not be drawn from the results of microhardness testing. Therefore, it cannot be …

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A Novel Bioactive Glass-Enhanced Orthodontic Bonding Resin: A Shear Bond Strength Study, Cole Johnson May 2011

A Novel Bioactive Glass-Enhanced Orthodontic Bonding Resin: A Shear Bond Strength Study, Cole Johnson

Theses and Dissertations

Enamel decalcification caused by poor oral hygiene is a significant problem in orthodontics. Bioactive glass-containing resins have been shown to release Ca2+ ions into surrounding solution. The purpose of this study was to determine the shear bond strength of four different compositions of orthodontic resin prepared with bioactive glass (N=20). Premolars were bonded using one of four BAG-BOND compositions. Brackets were debonded and ARI scores were given. The mean shear bond strength was 7.23 ± 2.47 MPa (62 BAG-BOND), 8.25 ± 2.87 MPa (65 BAG-BOND), 8.78 ± 3.08 MPa (81BAG-BOND) and 5.80 ± 2.27 MPa (85 BAG-BOND). 65 and 81 …

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