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Full-Text Articles in Medicine and Health Sciences

Characterization Of The Sero-Reactivity Of Proteins Map1152 And Map1156 From Mycobacterium Avium Subspecies Paratuberculosis, Avery L. Paulson Dec 2010

Characterization Of The Sero-Reactivity Of Proteins Map1152 And Map1156 From Mycobacterium Avium Subspecies Paratuberculosis, Avery L. Paulson

School of Veterinary and Biomedical Sciences: Dissertations, Theses, and Student Research

Mycobacterium avium subsp. paratuberculosis (MAP) causes Johne’s disease (JD) in ruminants. Development of genetic tools and completion of the MAP genome sequencing project expanded opportunities for antigen discovery. In this thesis, I review the current trends in diagnosis and disease control of JD and present the results of the studies on the seroreactivity of two proteins encoded for by the MAP1152-MAP1156 gene cluster. MAP1152 encodes for a PPE protein and MAP1156 encodes a diacylglycerol acyltransferase involved in triglyceride metabolism and classified in the uncharacterized protein family UPF0089. Maltose-binding protein (MBP) tagged recombinant MAP proteins were purified from Escherichia coli. Western …


Mycobacterial Diseases In Wildlife, Gary W. Witmer, Thomas J. Deliberto, Kurt C. Vercauteren, Peter Butchko Jan 2003

Mycobacterial Diseases In Wildlife, Gary W. Witmer, Thomas J. Deliberto, Kurt C. Vercauteren, Peter Butchko

Michigan Bovine Tuberculosis Bibliography and Database

Mycobacterium infections occur in numerous wildlife species worldwide and this bacterial genus can also cause disease in humans and livestock. Two Mycobacterium species and one subspecies that infect wildlife are important from a wildlife damage management perspective. Mycobacterium avium, avian tuberculosis, is a ubiquitous and cosmopolitan disease of wild and domestic birds. Wild and domestic ruminants are host to M. avium paratuberculosis, also known as Johne’s disease. Finally, Mycobaterium bovis, bovine tuberculosis, is primarily associated with domestic and wild bovines and ungulates, but also infects many other species of mammals. Eradicating these diseases from wildlife populations is …


The Incidence Of Avian Tuberculosis In Mammals Other Than Swine, L. Van Es, H. M. Martin Aug 1930

The Incidence Of Avian Tuberculosis In Mammals Other Than Swine, L. Van Es, H. M. Martin

Historical Research Bulletins of the Nebraska Agricultural Experiment Station

The recognition of a very widespread and intense distribution of avian tuberculosis on the farms of a wide area of the United States, as well as the involvement of a mammalian species also, brought to the foreground the question whether or not the great prevalence of poultry tuberculosis could be of importance also from a public health point of view. This phase of the problem not only pertains to the people on the farms but likewise is of fundamental importance to the consumers of poultry produce. European authors had already identified the avian tubercle bacillus in human lesions while in …