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Bovine Tuberculosis (Mycobacterium Bovis) In Wildlife In Spain, Alicia Aranaz, Lucía De Juan, Natalia Montero, Celia Sanchez, Margarita Galka, Consuelo Delso, Julio Alvarez, Beatriz Romero, Javier Bezos, Ana I. Vela, Victor Briones, Ana Mateos, Lucas Domínguez
Bovine Tuberculosis (Mycobacterium Bovis) In Wildlife In Spain, Alicia Aranaz, Lucía De Juan, Natalia Montero, Celia Sanchez, Margarita Galka, Consuelo Delso, Julio Alvarez, Beatriz Romero, Javier Bezos, Ana I. Vela, Victor Briones, Ana Mateos, Lucas Domínguez
Michigan Bovine Tuberculosis Bibliography and Database
Mycobacterium bovis infection in wildlife and feral species is a potential source of infection for livestock and a threat to protected and endangered species. The aim of this study was to identify Spanish wild animal species infected with M. bovis through bacteriological culture and spacer oligonucleotide typing (spoligotyping) of isolates for epidemiological purposes. This study included samples from red deer (Cervus elaphus), fallow deer (Dama dama), wild boar (Sus scrofa), Iberian lynx (Lynx pardina), hare (Lepus europaeus), and cattle (Bos taurus). They were collected in several geographical areas …
Shared Feed As A Means Of Deer-To-Deer Transmission Of Mycobacterium Bovis, Mitchell V. Palmer, W. Ray Waters, Diana L. Whipple
Shared Feed As A Means Of Deer-To-Deer Transmission Of Mycobacterium Bovis, Mitchell V. Palmer, W. Ray Waters, Diana L. Whipple
Michigan Bovine Tuberculosis Bibliography and Database
To determine the ability of experimentally inoculated white-tailed deer (Odocoileus virginianus) to transmit Mycobacterium bovis to naive deer through the sharing of feed, four deer were intratonsillarly inoculated with 4x105 colony-forming units of M. bovis. On a daily basis, feed not consumed by inoculated deer after approximately 8 hr was offered to four naıve deer maintained in a separate pen, where direct contact, aerosol transmission, or transmission through personnel were prevented. After 150 days, naıve deer were euthanized and examined. All naıve deer had lesions consistent with tuberculosis and M. bovis was isolated from various tissues. …
Evaluation Of An In Vitro Blood-Based Assay To Detect Production Of Interferon-Γ By Mycobacterium Bovis–Infected White-Tailed Deer (Odocoileus Virginianus), Mitchell V. Palmer, W. Ray Waters, Diana L. Whipple, Ralph E. Slaughter, Stephen L. Jones
Evaluation Of An In Vitro Blood-Based Assay To Detect Production Of Interferon-Γ By Mycobacterium Bovis–Infected White-Tailed Deer (Odocoileus Virginianus), Mitchell V. Palmer, W. Ray Waters, Diana L. Whipple, Ralph E. Slaughter, Stephen L. Jones
Michigan Bovine Tuberculosis Bibliography and Database
Tuberculosis due to Mycobacterium bovis in captive Cervidae was identified as an important disease in the United States in 1990 and prompted the addition of captive Cervidae to the USDA Uniform Methods and Rules for eradication of bovine tuberculosis. As well, M. bovis infection was identified in free-ranging white-tailed deer in northeast Michigan in 1995. Tuberculosis in both captive and free-ranging Cervidae represents a serious challenge to the eradication of M. bovis infection from the United States. Currently, the only approved antemortem tests for tuberculosis in Cervidae are the intradermal tuberculin skin test and the blood tuberculosis test (BTB). At …
Bovine Tuberculosis In Swedish Farmed Deer: Detection And Control Of The Disease, Helene Wahlström
Bovine Tuberculosis In Swedish Farmed Deer: Detection And Control Of The Disease, Helene Wahlström
Michigan Bovine Tuberculosis Bibliography and Database
Bovine tuberculosis (BTB) was introduced into Swedish farmed deer herds in 1987. Epidemiological investigations showed that 10 deer herds had become infected (July 1994) and a common source of infection, a consignment of 168 imported farmed fallow deer, was identified (I).
As trace-back of all imported and in-contact deer was not possible, a control program, based on tuberculin testing, was implemented in July 1994. As Sweden has been free from BTB since 1958, few practicing veterinarians had experience in tuberculin testing. In this test, result relies on the skill, experience and conscientiousness of the testing veterinarian. Deficiencies in performing the …
The Economics Of Managing Wildlife Disease, Richard D. Horan, Christopher A. Wolf
The Economics Of Managing Wildlife Disease, Richard D. Horan, Christopher A. Wolf
Michigan Bovine Tuberculosis Bibliography and Database
The spread of infectious disease among and between wild and domesticated animals has become a major problem worldwide. Upon analyzing the dynamics of wildlife growth and infection when the diseased animals cannot be identified separately from healthy wildlife prior to the kill, we find that harvest-based strategies alone have no impact on disease transmission. Other controls that directly influence disease transmission and/or mortality are required. Next, we analyze the socially optimal management of infectious wildlife. The model is applied to the problem of bovine tuberculosis among Michigan white-tailed deer, with non-selective harvests and supplemental feeding being the control variables. Using …
Michigan Bovine Tuberculosis Eradication Project: Activities Report 2003, Bridget Patrick
Michigan Bovine Tuberculosis Eradication Project: Activities Report 2003, Bridget Patrick
Michigan Bovine Tuberculosis Bibliography and Database
Bovine tuberculosis (TB) is an infectious bacterial disease and poses a risk to domestic livestock, wildlife and public health in the United States (U.S). In 1917, the U.S. government began a comprehensive national bovine TB eradication program. The disease has been nearly eradicated from livestock in the U.S., but areas of infection resurface periodically. Michigan was declared free of bovine TB in 1975 and received Disease Free status in 1979. In 1975 a free-ranging white-tailed deer in Alcona County was confirmed to be bovine TB positive. It was thought to be an anomaly, and no policy was adopted to look …
Genealogical Relationships Influence The Probability Of Infection With Bovine Tuberculosis And Microgeographic Genetic Structure In Free-Ranging White-Tailed Deer, Julie Anne Blanchong
Genealogical Relationships Influence The Probability Of Infection With Bovine Tuberculosis And Microgeographic Genetic Structure In Free-Ranging White-Tailed Deer, Julie Anne Blanchong
Michigan Bovine Tuberculosis Bibliography and Database
Zoonoses are of increasing importance to wildlife conservation and human health. It has become increasingly recognized that wildlife ecology plays a key role in disease transmission in wildlife populations. In domestic populations, contacts among individuals are controlled by humans and disease transmission is often density dependent. Unlike domestic animals, wildlife populations often have complex social systems in whch contacts among individuals are not solely density dependent, and can play an important role in the transmission and maintenance of disease.
Prevalence Of Chronic Wasting Disease And Bovine Tuberculosis In Free-Ranging Deer And Elk In South Dakota, Christopher N. Jacques, Jonathan A. Jenks, Allen L. Jenny, Steven L. Griffin
Prevalence Of Chronic Wasting Disease And Bovine Tuberculosis In Free-Ranging Deer And Elk In South Dakota, Christopher N. Jacques, Jonathan A. Jenks, Allen L. Jenny, Steven L. Griffin
Michigan Bovine Tuberculosis Bibliography and Database
Heads of hunter-harvested deer and elk were collected throughout South Dakota (USA) and within established chronic wasting disease (CWD) surveillance areas from 1997–2002 to determine infection with CWD and bovine tuberculosis (TB). We used immunohistochemistry to detect CWD-infected individuals among 1,672 deer and elk sampled via geographically targeted surveillance. A total of 537 elk (Cervus elaphus nelsoni), 813 white-tailed deer (Odocoileus virginianus), and 322 mule deer (O. hemionus) was sampled for CWD. Estimated overall prevalence and associated confidence intervals (95%) in white-tailed deer was 0.001% (0–0.007%). Similarly, estimated overall prevalence in elk and mule …
Bovine Tuberculosis In Michigan: Understanding Stakeholder Attitudes Toward The Disease And Eradication Efforts, Meegan Leah Dorn
Bovine Tuberculosis In Michigan: Understanding Stakeholder Attitudes Toward The Disease And Eradication Efforts, Meegan Leah Dorn
Michigan Bovine Tuberculosis Bibliography and Database
Bovine tuberculosis has been discovered at unprecedented levels in Michigan wildlife, especially white-tailed deer (Odocoileus virginianus). Human behaviors, particularly the use of bait and feed, have facilitated the spread of the disease into free-ranging white-tailed deer populations. Policies aimed at eradicating bovine tuberculosis in Michigan require public compliance and cooperation in order to be successful. Because of the human contribution to the spread of bovine tuberculosis in Michigan wildlife, and the social nature of subsequent bovine tuberculosis eradication policies, we conducted a survey of bovine TB issue stakeholder groups in northeast Michigan, including non-resident hunters, resident hunters, livestock …
Are There “Hot Spots” Of Bovine Tuberculosis In The Free-Ranging White-Tailed Deer (Odocoileus Virginianus) Herd Of Northeastern Michigan?, Brandi Danielle Hughey
Are There “Hot Spots” Of Bovine Tuberculosis In The Free-Ranging White-Tailed Deer (Odocoileus Virginianus) Herd Of Northeastern Michigan?, Brandi Danielle Hughey
Michigan Bovine Tuberculosis Bibliography and Database
This project looks at whether high case frequency areas or “hot spots” of bovine tuberculosis (tb) exist in free ranging white-tailed deer in northeastern Michigan, and examines the factors associated with them. Michigan Department of Natural Resources researchers have been collecting deer heads annually since 1996 in the five county area of Alcona, Alpena, Montmorency, Oscoda, and Presque Isle as part of an effort to manage an outbreak of bovine tb in the wild white-tailed deer population. From these heads a database containing age, sex, and harvest or collection location information was constructed. The townships within these five counties were …
Bovine Tuberculosis In Elk (Cervus Elaphus Manitobensis) Near Riding Mountain National Park, Manitoba, From 1992 To 2002
Michigan Bovine Tuberculosis Bibliography and Database
From 1991 to April 2003, outbreaks of bovine tuberculosis (TB caused by Mycobacterium bovis) have been found in 11 cattle herds surrounding Riding Mountain National Park (RMNP). Located in southwestern Manitoba, RMNP and the surrounding area are home to a free-ranging herd of 2500 to 4000 elk that have been implicated as being a wildlife reservoir of M. bovis infection. Indirect contact between cattle and elk that feed during the winter on the same large, round hay bales is presumed to be the most likely mode of transmission between the species (1).
Mycobacterial Diseases In Wildlife, Gary W. Witmer, Thomas J. Deliberto, Kurt C. Vercauteren, Peter Butchko
Mycobacterial Diseases In Wildlife, Gary W. Witmer, Thomas J. Deliberto, Kurt C. Vercauteren, Peter Butchko
Michigan Bovine Tuberculosis Bibliography and Database
Mycobacterium infections occur in numerous wildlife species worldwide and this bacterial genus can also cause disease in humans and livestock. Two Mycobacterium species and one subspecies that infect wildlife are important from a wildlife damage management perspective. Mycobacterium avium, avian tuberculosis, is a ubiquitous and cosmopolitan disease of wild and domestic birds. Wild and domestic ruminants are host to M. avium paratuberculosis, also known as Johne’s disease. Finally, Mycobaterium bovis, bovine tuberculosis, is primarily associated with domestic and wild bovines and ungulates, but also infects many other species of mammals. Eradicating these diseases from wildlife populations is …
Feral Swine - Are They A Disease Threat To Livestock In The United States?, Gary W. Witmer, Robert B. Sanders, Arnold C. Taft
Feral Swine - Are They A Disease Threat To Livestock In The United States?, Gary W. Witmer, Robert B. Sanders, Arnold C. Taft
Michigan Bovine Tuberculosis Bibliography and Database
Feral swine populations provide both benefits and liabilities to citizens of the United States. Their expanding range and increasing densities, however, have raised concern over the adverse environmental and agricultural effects and the increased risk of disease transmission between feral swine and livestock. We discuss the role of feral swine in the transmission of wildlife diseases and, in particular, in diseases of national significance to the livestock industry. We also discuss available management tools and strategies for reducing feral swine populations, minimizing damage or disease occurrences and eradicating populations when deemed appropriate. Finally, we note areas of research that may …
The Risk Of Disease Transmission To Livestock Posed By Contamination Of Farm Stored Feed By Wildlife Excreta, M. J. Daniels, M. R. Hutchings, A. Greig
The Risk Of Disease Transmission To Livestock Posed By Contamination Of Farm Stored Feed By Wildlife Excreta, M. J. Daniels, M. R. Hutchings, A. Greig
Michigan Bovine Tuberculosis Bibliography and Database
Livestock feed is susceptible to contamination from wildlife excreta during on farm storage. Pathogens associated with diseases such as paratuberculosis, salmonella and cryptosporidiosis are present in wild rodent and bird excreta. Feed stores on four farms in the east of Scotland were monitored monthly over the winter of 1998/9 to quantify the levels of wildlife faecal contamination. A mean of 79.9 rodent (95% confidence interval: 37.5–165.9) and 24.9 (14.3–41.7) bird faeces were deposited per m2 of stored feed per month. It was estimated that individual cattle and sheep could encounter 1626 and 814 wildlife faeces over the winter.
A …
Spatial And Temporal Spread Of Bovine Tuberculosis In Wild White-Tailed Deer In Michigan, Graham J. Hickling, Stephen M. Schmitt, Daniel J. O'Brien
Spatial And Temporal Spread Of Bovine Tuberculosis In Wild White-Tailed Deer In Michigan, Graham J. Hickling, Stephen M. Schmitt, Daniel J. O'Brien
Michigan Bovine Tuberculosis Bibliography and Database
In 1975, a wild white-tailed deer infected with bovine tuberculosis was shot in the northeastern Lower Peninsula, Michigan. The shooting of a second infected deer in the same area in 1994 triggered ongoing disease surveillance in the region. By 2002, bovine tuberculosis had been confirmed in 12 Michigan counties: from 449 deer; two elk; 41 non-cervid wildlife; one captive cervid facility and 28 cattle herds. We analyzed geographic spread of disease since the surveillance began and investigated factors influencing the prevalence of disease within the infected area. These analyses reveal that 78 percent of tuberculous deer came from within a …
Aerosol Exposure Of White-Tailed Deer (Odocoileus Virginianus) To Mycobacterium Bovis, Mitchell V. Palmer, W. Ray Waters, Diana L. Whipple
Aerosol Exposure Of White-Tailed Deer (Odocoileus Virginianus) To Mycobacterium Bovis, Mitchell V. Palmer, W. Ray Waters, Diana L. Whipple
Michigan Bovine Tuberculosis Bibliography and Database
Tuberculosis due to Mycobacterium bovis affects both captive and free-ranging Cervidae in the United States. Various animal models have been developed to study tuberculosis of both humans and animals. Generally, tuberculosis is transmitted by aerosol and oral routes. Models of aerosol exposure of large animals to M. bovis are uncommon. In order to develop a reliable method of aerosol exposure of white-tailed deer (Odocoileus virginianus) to M. bovis, 12 healthy white-tailed deer, aged 8–10 mo, were infected by aerosol exposure to 2x105 to 1x106 colony forming units (CFU) (high dose, n=4) of M. bovis or …
Mycobacterial Diseases In Wildlife, Gary Witmer, Thomas J. Deliberto, Kurt C. Vercauteren, Peter Butchko
Mycobacterial Diseases In Wildlife, Gary Witmer, Thomas J. Deliberto, Kurt C. Vercauteren, Peter Butchko
Michigan Bovine Tuberculosis Bibliography and Database
Mycobacterium infections occur in numerous wildlife species worldwide and this bacterial genus can also cause disease in humans and livestock. Two Mycobacterium species and one subspecies that infect wildlife are important from a wildlife damage management perspective. Mycobacterium avium, avian tuberculosis, is a ubiquitous and cosmopolitan disease of wild and domestic birds. Wild and domestic ruminants are host to M. avium paratuberculosis, also known as Johne’s disease. Finally, Mycobaterium bovis, bovine tuberculosis, is primarily associated with domestic and wild bovines and ungulates, but also infects many other species of mammals. Eradicating these diseases from wildlife populations is …
Dynamics Of Bovine Tuberculosis In Wild White-Tailed Deer In Michigan, Graham J. Hickling
Dynamics Of Bovine Tuberculosis In Wild White-Tailed Deer In Michigan, Graham J. Hickling
Michigan Bovine Tuberculosis Bibliography and Database
In mid-2001, the author of this report was invited to undertake an exploratory analysis of Michigan Department of Natural Resources’ data on bovine tuberculosis (TB) infection in wild white-tailed (Odocoileus virginianus) in the northeastern Lower Peninsula of the state. The aims of this analysis were:
• to quantify the geographic spread of tuberculous deer in Michigan;
• to investigate key factors influencing the prevalence of disease in the core of the infected area;
• to interpret the results in light of overseas experience with wildlife TB, with a view to
recommending how current management of the disease might …
Environmental And Farm Management Factors Associated With Tuberculosis On Cattle Farms In Northeastern Michigan, John B. Kaneene, Colleen S. Bruning-Fann, Larry M. Granger, Roseann Miller, Barbara A. Porter-Spalding
Environmental And Farm Management Factors Associated With Tuberculosis On Cattle Farms In Northeastern Michigan, John B. Kaneene, Colleen S. Bruning-Fann, Larry M. Granger, Roseann Miller, Barbara A. Porter-Spalding
Michigan Bovine Tuberculosis Bibliography and Database
Objective—To identify major environmental and farm management factors associated with the occurrence of tuberculosis (TB) on cattle farms in northeastern Michigan.
Design—Case-control study.
Sample Population—17 cattle farms with infected cattle and 51 control farms.
Procedure—Each case farm (laboratory confirmed diagnosis of Mycobacterium bovis infection) was matched with 2 to 4 control farms (negative whole-herd test results within previous 12 months) on the basis of type of farm (dairy or beef) and location. Cattle farm data were collected from in-person interviews and mailed questionnaires. Wildlife TB data were gathered through state wildlife surveillance. Environmental data were gathered …
Susceptibility Of Raccoons (Procyon Lotor) To Infection With Mycobacterium Bovis, Mitchell V. Palmer, W. Ray Waters, Diana L. Whipple
Susceptibility Of Raccoons (Procyon Lotor) To Infection With Mycobacterium Bovis, Mitchell V. Palmer, W. Ray Waters, Diana L. Whipple
Michigan Bovine Tuberculosis Bibliography and Database
Tuberculosis due to Mycobacterium bovis infection is endemic in white-tailed deer (Odocoileus virginianus) in the northeastern portion of the lower Michigan peninsula (USA). Various wild carnivores and omnivores, including raccoons (Procyon lotor), are infected with M. bovis within the endemic area. To investigate the pathogenesis of tuberculosis in raccoons and the likelihood of M. bovis transmission from infected raccoons to other susceptible hosts, we experimentally inoculated raccoons with single oral doses of M. bovis (ranging from 30 to 1.7 x 105 colony forming units [CFU]), five daily oral doses of M. bovis (ranging from 10 …
Lesion Development In White-Tailed Deer (Odocoileus Virginianus) Experimentally Infected With Mycobacterium Bovis, M. V. Palmer, W. R. Waters, D. L. Whipple
Lesion Development In White-Tailed Deer (Odocoileus Virginianus) Experimentally Infected With Mycobacterium Bovis, M. V. Palmer, W. R. Waters, D. L. Whipple
Michigan Bovine Tuberculosis Bibliography and Database
The recent discovery of tuberculosis in free-living white-tailed deer in northeastern Michigan underscores the need for increased understanding of the pathogenesis of tuberculosis in wildlife species. To investigate lesion development in white-tailed deer, 32 deer were experimentally infected by intratonsilar instillation of 300 colony-forming units of Mycobacterium bovis. Three deer each were euthanatized and examined at days 15, 28, 42, and 56 after inoculation, and five deer each were euthanatized and examined at days 89, 180, 262, and 328 after inoculation. Microscopic lesions first were seen in the medial retropharyngeal lymph node and lung 28 and 42 days after …
Nitric Oxide Production As An Indication Of Mycobacterium Bovis Infection In White-Tailed Deer (Odocoileus Virginianus), W. R. Waters, M. V. Palmer, R. E. Sacco, D. L. Whipple
Nitric Oxide Production As An Indication Of Mycobacterium Bovis Infection In White-Tailed Deer (Odocoileus Virginianus), W. R. Waters, M. V. Palmer, R. E. Sacco, D. L. Whipple
Michigan Bovine Tuberculosis Bibliography and Database
White-tailed deer ( Odocoileus virginianus ) are reservoirs for Mycobacterium bovis in northeast Michigan, USA. Production of nitric oxide (NO) by activated macrophages is a potent mechanism of mycobacterial killing. The capacity of macrophages to produce NO, however, varies among mammalian species. The objective of this study was to determine if mononuclear cells from white-tailed deer produce nitrite as an indication of NO production and, if so, is NO produced in response to stimulation with M. bovis antigens. Supernatants were harvested from adherent peripheral blood mononuclear cell (PBMC) cultures that had been stimulated with either Mannheimia haemolytica lipopolysaccharide (LPS) or …
Mycobacterium Bovis–Infected White-Tailed Deer (Odocoileus Virginianus): Detection Of Immunoglobulin Specific To Crude Mycobacterial Antigens By Elisa, W. Ray Waters, Mitchell V. Palmer, Diana L. Whipple
Mycobacterium Bovis–Infected White-Tailed Deer (Odocoileus Virginianus): Detection Of Immunoglobulin Specific To Crude Mycobacterial Antigens By Elisa, W. Ray Waters, Mitchell V. Palmer, Diana L. Whipple
Michigan Bovine Tuberculosis Bibliography and Database
White-tailed deer (Odocoileus virginianus) have recently emerged as a source of Mycobacterium bovis infection for cattle within North America. The objective of this study was to evaluate the antibody response of M. bovis–infected deer to crude mycobacterial antigens. Deer were experimentally inoculated with M. bovis strain 1315 either by intratonsilar instillation or by exposure to M. bovis–infected (i.e., in contact) deer. To determine the time course of the response, including the effects of antigen administration for comparative cervical skin testing, serum was collected periodically and evaluated by enzyme-linked immunosorbent assay (ELISA) for immunoglobulin (i.e., IgG heavy …
Bovine Tuberculosis In Michigan Wildlife And Livestock, Stephen M. Schmitt, Daniel J. O'Brien, Colleen S. Brunning-Fann, Scott D. Fitzgerald
Bovine Tuberculosis In Michigan Wildlife And Livestock, Stephen M. Schmitt, Daniel J. O'Brien, Colleen S. Brunning-Fann, Scott D. Fitzgerald
Michigan Bovine Tuberculosis Bibliography and Database
Since 1994, the state of Michigan has recognized a problem with bovine tuberculosis (TB), caused by Mycobacterium bovis, in wild white-tailed deer from a 12-county area in northeastern Lower Michigan. A total of 65,000 free-ranging deer have been tested, and 340 have been found to be positive for M. bovis. The disease has been found in other wildlife species, and, in 1998, in domestic cattle, where to date 13 beef cattle and 2 dairy cattle herds have been diagnosed with bovine TB. Unfortunately, the situation is unique in that there have never been reports of self-sustaining bovine TB …
Tonsillar Lesions In White-Tailed Deer (Odocoileus Virginianus) Naturally Infected With Mycobacterium Bovis, M. V. Palmer, D. L. Whipple, K. L. Butler, S. D. Fitzgerald, C. S. Bruning-Fann, S. M. Schmitt
Tonsillar Lesions In White-Tailed Deer (Odocoileus Virginianus) Naturally Infected With Mycobacterium Bovis, M. V. Palmer, D. L. Whipple, K. L. Butler, S. D. Fitzgerald, C. S. Bruning-Fann, S. M. Schmitt
Michigan Bovine Tuberculosis Bibliography and Database
In 1994, a free-living white-tailed deer (Odocoileus virginianus) in Michigan was diagnosed with tuberculosis caused by Mycobacterium bovis (Schmitt and others 1997). Subsequent surveys conducted by the Michigan Department of Natural Resources and Michigan State University Animal Health Diagnostic Laboratory identified an epidemic of M bovis infection in free-living white-tailed deer in northeast Michigan (Schmitt and others 1997, O'Brien and others 2001). This represents the first known reservoir of M bovis in free-living wildlife in the USA, and the first known epidemic of tuberculosis in white-tailed deer anywhere in the world.
Milk Containing Mycobacterium Bovis As A Source Of Infection For White-Tailed Deer Fawns (Odocoileus Virginianus), M. V. Palmer, W. R. Waters, D. L. Whipple
Milk Containing Mycobacterium Bovis As A Source Of Infection For White-Tailed Deer Fawns (Odocoileus Virginianus), M. V. Palmer, W. R. Waters, D. L. Whipple
Michigan Bovine Tuberculosis Bibliography and Database
Setting:White-tailed deer represent the first wildlife reservoir of Mycobacterium bovis in the United States. The behavior of does with nursing fawns provides several potential mechanisms for disease transmission. Little information exists concerning transmission between doe and fawn, specifically transmammary transmission.
Objective: Determine if fawns can become infected by ingestion of milk replacer containing M. bovis, thus simulating transmission from doe to fawn through contaminated milk.
Design: Seventeen, 21-day-old white-tailed deer fawns were inoculated orally with 2x108 CFU (high dose, n=5), 2.5 x 105 to 2.5 x 106 CFU (medium dose, n=5), and 1x104 CFU (low …
Experimental Deer-To-Deer Transmission Of Mycobacterium Bovis, Mitchell V. Palmer, Diana L. Whipple, W. Ray Waters
Experimental Deer-To-Deer Transmission Of Mycobacterium Bovis, Mitchell V. Palmer, Diana L. Whipple, W. Ray Waters
Michigan Bovine Tuberculosis Bibliography and Database
Objective—To determine whether Mycobacterium bovis can be transmitted from experimentally infected deer to uninfected in-contact deer.
Animals—Twenty-three 6-month-old white-tailed deer.
Procedure—On day 0, M bovis (2 X 108 colony-forming units) was administered by intratonsillar instillation to 8 deer; 3 control deer received saline (0.9% NaCl) solution. Eight in-contact deer were comingled with inoculated deer from day 21. On day 120, inoculated deer were euthanatized and necropsied. On day 180, 4 in-contact deer were euthanatized, and 4 new incontact deer were introduced. On day 360, all in-contact deer were euthanatized. Rectal, oral, and nasal swab specimens and …
Bovine Tuberculosis In Free-Ranging Carnivores From Michigan, Colleen S. Bruning-Fann, Stephen M. Schmitt, Scott D. Fitzgerald, Jean S. Fierke, Paul D. Friedrich, John B. Kaneene, Kathy A. Clarke, Kelly L. Butler, Janet B. Payeur, Diana L. Whipple, Thomas M. Cooley, Janice M. Miller, Darian P. Muzo
Bovine Tuberculosis In Free-Ranging Carnivores From Michigan, Colleen S. Bruning-Fann, Stephen M. Schmitt, Scott D. Fitzgerald, Jean S. Fierke, Paul D. Friedrich, John B. Kaneene, Kathy A. Clarke, Kelly L. Butler, Janet B. Payeur, Diana L. Whipple, Thomas M. Cooley, Janice M. Miller, Darian P. Muzo
Michigan Bovine Tuberculosis Bibliography and Database
During a survey of carnivores and omnivores for bovine tuberculosis conducted in Michigan (USA) since 1996, Mycobacterium bovis was cultured from lymph nodes pooled from six coyotes (Canis latrans) (four adult female, two adult male), two adult male raccoons (Procyon lotor), one adult male red fox (Vulpes vulpes), and one 1.5-yr-old male black bear (Ursus americanus). One adult, male bobcat (Felis rufus) with histologic lesions suggestive of tuberculosis was negative on culture but positive for organisms belonging to the Mycobacterium tuberculosis complex when tested by polymerase chain reaction. All the …
Bovine Tuberculosis In Brushtail Possums (Trichosurus Vulpecula): Studies On Vaccination, Experimental Infection, And Disease Transmission, L. A. L. Corner
Bovine Tuberculosis In Brushtail Possums (Trichosurus Vulpecula): Studies On Vaccination, Experimental Infection, And Disease Transmission, L. A. L. Corner
Michigan Bovine Tuberculosis Bibliography and Database
The objectives of the research program were to obtain a better understanding of BCG as a tuberculosis vaccine in possums, and assess its potential as a tool for controlling tuberculosis in wild possum populations. A series of vaccination and challenge experiments were conducted, as well as studies on alternative experimental infection procedures. The program included two field studies, one on the epidemiology of tuberculosis in a population of possums regenerating after localised possum eradication, and the other examined the efficacy of BCG vaccine in a wild population in which tuberculosis was endemic.
The first experiments confirmed the earlier published findings …
Movement Patterns And Behavior At Winter-Feeding And Fall Baiting Stations In A Population Of White-Tailed Deer Infected With Bovine Tuberculosis In The Northeastern Lower Peninsula Of Michigan, Mark Stephen Garner
Michigan Bovine Tuberculosis Bibliography and Database
In 1994 bovine tuberculosis (Mycobacterium bovis) was discovered in a single free ranging white-tailed deer (Odocoileus virginianus) in northeastern Michigan (Deer Management Unit 452 @MU 452)). By the end of the 2000 hunting season, 325+ deer within the DMU 452 had been detected with M. bovis and it was generally believed that the disease had radiated from a single focus of infection. However, the presence of three TB positive deer discovered in 1999 well outside of DMU 452 suggested that M. bovis may be endemic at extremely low levels in Michigan white-tailed deer.
The primary mode …