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Full-Text Articles in Medicine and Health Sciences

Analysis Of Multigenerational Behavioral Effects Of Dietary Benzo[A]Pyrene Exposure In Adult Zebrafish, Mary Beth Gillespie May 2021

Analysis Of Multigenerational Behavioral Effects Of Dietary Benzo[A]Pyrene Exposure In Adult Zebrafish, Mary Beth Gillespie

Honors Theses

Benzo[a]pyrene (BaP) is a polycyclic aromatic hydrocarbon that is linked to negative reproductive and developmental effects in humans and animals. Because BaP is carcinogenic, and its continued presence in the environment allows it to be inhaled and ingested, better understanding of the effects of BaP is needed. To determine the behavioral effects of BaP exposure, zebrafish were used as a model. Wild-type zebrafish (5D) underwent two separate 21-day dietary exposures to 2.5 and 25 μg BaP/g fish to compare how BaP exposure affects locomotor activity. Following the dietary exposure, fish were mated to obtain and raise the F1 generation to …


Social Environment Changes During Covid-19 Quarantine, Aileen Jimenez May 2021

Social Environment Changes During Covid-19 Quarantine, Aileen Jimenez

Honors Theses

The purpose of this research project is to understand perceptions of the psychological, behavioral, and social impacts of COVID-19. Students at the University of Mississippi were invited to participate in an online questionnaire administered through Qualtrics. The questionnaire was composed of questions concerning health behaviors, including questions from the Depression, Anxiety and Stress Scale-21, Perceived Vulnerability to Disease Scale, Fear of Coronavirus-19 Scale, and the World Health Organization’s COVID-19 Snapshot Monitoring study. 274 students participated in the study. Overall, the results of this study suggested moderate distress across the sample, differences in sleep, exercise, and alcohol consumption during quarantine conditions, …


The Role Of Cannabinoid Receptor 2 In Zebrafish Toxicities Following Developmental Exposure To Thc Or Cbd, Haley Watts May 2021

The Role Of Cannabinoid Receptor 2 In Zebrafish Toxicities Following Developmental Exposure To Thc Or Cbd, Haley Watts

Honors Theses

As the laws concerning the regulation of Cannabis Sativa change across the globe, maternal use of cannabinoid-containing products during pregnancy is a greater concern than ever before. Little research has been conducted on the consequences of maternal use and developmental exposure to ∆9-tetrahydrocannabinol (THC) and cannabidiol (CBD. In this study, larval zebrafish (Danio rerio) were used to measure CBD and THC-mediated adverse outcomes including effects on larval length, eye area, and behavior in the cnr+/+ and cnr2-/- zebrafish strains where we discovered that cannabinoid exposure results in a decrease in each of these endpoints. Adult …