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Articles 1 - 5 of 5
Full-Text Articles in Medicine and Health Sciences
Effects Of Waterborne Benzo[A]Pyrene Embryonic Exposure On Development, Behavior, Reproduction, And Mitochondrial Bioenergetics In Zebrafish, Megha Patel
Honors Theses
Benzo[a]pyrene (BaP) is a polycyclic aromatic hydrocarbon (PAH) that is a known carcinogen leading to adverse effects in the development of both humans and animals. BaP is also continuously present in the environment leading to regular exposure via inhalation or ingestion. Because organisms’ early life stages can be more susceptible to contaminant exposure, our focus was on BaP’s adverse impacts on survival, length, weight, behavior, bioenergetic state, and fecundity following developmental exposures. To study BaP’s impacts, zebrafish (Danio rerio) were used as a model organism. BaP is a ligand for the aryl hydrocarbon receptor (AHR in humans; Ahr in …
Analysis Of Multigenerational Behavioral Effects Of Dietary Benzo[A]Pyrene Exposure In Adult Zebrafish, Mary Beth Gillespie
Analysis Of Multigenerational Behavioral Effects Of Dietary Benzo[A]Pyrene Exposure In Adult Zebrafish, Mary Beth Gillespie
Honors Theses
Benzo[a]pyrene (BaP) is a polycyclic aromatic hydrocarbon that is linked to negative reproductive and developmental effects in humans and animals. Because BaP is carcinogenic, and its continued presence in the environment allows it to be inhaled and ingested, better understanding of the effects of BaP is needed. To determine the behavioral effects of BaP exposure, zebrafish were used as a model. Wild-type zebrafish (5D) underwent two separate 21-day dietary exposures to 2.5 and 25 μg BaP/g fish to compare how BaP exposure affects locomotor activity. Following the dietary exposure, fish were mated to obtain and raise the F1 generation to …
The Role Of Cannabinoid Receptor 2 In Zebrafish Toxicities Following Developmental Exposure To Thc Or Cbd, Haley Watts
The Role Of Cannabinoid Receptor 2 In Zebrafish Toxicities Following Developmental Exposure To Thc Or Cbd, Haley Watts
Honors Theses
As the laws concerning the regulation of Cannabis Sativa change across the globe, maternal use of cannabinoid-containing products during pregnancy is a greater concern than ever before. Little research has been conducted on the consequences of maternal use and developmental exposure to ∆9-tetrahydrocannabinol (THC) and cannabidiol (CBD. In this study, larval zebrafish (Danio rerio) were used to measure CBD and THC-mediated adverse outcomes including effects on larval length, eye area, and behavior in the cnr+/+ and cnr2-/- zebrafish strains where we discovered that cannabinoid exposure results in a decrease in each of these endpoints. Adult …
Social Environment Changes During Covid-19 Quarantine, Aileen Jimenez
Social Environment Changes During Covid-19 Quarantine, Aileen Jimenez
Honors Theses
The purpose of this research project is to understand perceptions of the psychological, behavioral, and social impacts of COVID-19. Students at the University of Mississippi were invited to participate in an online questionnaire administered through Qualtrics. The questionnaire was composed of questions concerning health behaviors, including questions from the Depression, Anxiety and Stress Scale-21, Perceived Vulnerability to Disease Scale, Fear of Coronavirus-19 Scale, and the World Health Organization’s COVID-19 Snapshot Monitoring study. 274 students participated in the study. Overall, the results of this study suggested moderate distress across the sample, differences in sleep, exercise, and alcohol consumption during quarantine conditions, …
Impacts Of Embryonic Exposure To Cannabidiol Or ∆9-Tetrahydrocannabinol On Zebrafish (Danio Rerio) Frailty In F0 And F1 Generations, Anika Faruque
Impacts Of Embryonic Exposure To Cannabidiol Or ∆9-Tetrahydrocannabinol On Zebrafish (Danio Rerio) Frailty In F0 And F1 Generations, Anika Faruque
Honors Theses
Exposure to cannabinoids during critical development periods has increased with epileptic children being commonly prescribed CBD for seizures and pregnant women taking it recreationally. Many studies have been done on the possible benefits and drawbacks of cannabinoid exposure on the human brain, but not much is known about how it can affect the developing brain long-term. To see the potential adverse effects of cannabinoid exposure during critical stages of development and discover potential developmental origins of disease in consuming cannabinoids during embryogenesis, zebrafish embryos (6-96 hours post fertilization) were exposed to varying concentrations of CBD (0.02, 0.1, 0.5 µM), THC …