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Medicine and Health Sciences Commons

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University of Central Florida

2019

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Full-Text Articles in Medicine and Health Sciences

The Scoop Vol. 6 Issue 9, December 2019, Health Sciences Library Dec 2019

The Scoop Vol. 6 Issue 9, December 2019, Health Sciences Library

Volume 6

Latest news and events from the Health Sciences Library in our monthly newsletter for December 2019.


The Scoop, Vol. 6 Issue 8, November 2019, Health Sciences Library Nov 2019

The Scoop, Vol. 6 Issue 8, November 2019, Health Sciences Library

Volume 6

Latest news and events from the Health Sciences Library in our monthly newsletter for November 2019.


Seminole State College Cure Research Program: From The Classroom To Collaboration, Maya Patrice Byfield Phd Oct 2019

Seminole State College Cure Research Program: From The Classroom To Collaboration, Maya Patrice Byfield Phd

Florida Statewide Symposium: Best Practices in Undergraduate Research

It is believed that if students are taught inductively in their first 2 years, it could induce many of them to seek research experiences later in their academic careers. To do this, we initiated an effort to promote engagement in research topics and faculty development. First, collaboration between one faculty member at SSC and a Principal Investigator at the Sanford-Burnham Institute was developed. This collaboration resulted in the creation of several internships at the Institute for students in the newly developed STEM research class. Second, to increase student engagement, the biology department developed a research focused colloquium series. Each fall …


The Scoop, Vol. 6 Issue 7, October 2019, Health Sciences Library Oct 2019

The Scoop, Vol. 6 Issue 7, October 2019, Health Sciences Library

Volume 6

Latest news and events from the Health Sciences Library in our monthly newsletter for October 2019.


The Scoop, Vol. 6 Issue 6, September 2019, Health Sciences Library Sep 2019

The Scoop, Vol. 6 Issue 6, September 2019, Health Sciences Library

Volume 6

Latest news and events from the Health Sciences Library in our monthly newsletter for September 2019.


Rhm Editor Blake Scott's Interview With Lisa Keränen, Blake Scott, Lisa Keranen Aug 2019

Rhm Editor Blake Scott's Interview With Lisa Keränen, Blake Scott, Lisa Keranen

Rhetoric of Health & Medicine

Transcription of RHM Editor Blake Scott's Interview with influential rhetorician of health and medicine and bioethics scholar Lisa Keränen to get her perspective on the first special issue of the Rhetoric of Health and Medicine journal on public health, co-edited by editor Lisa Melonçon and by guest editor Jennifer Malkowski.


The Scoop, Vol. 6 Issue 5, August 2019, Health Sciences Library Aug 2019

The Scoop, Vol. 6 Issue 5, August 2019, Health Sciences Library

Volume 6

Latest news and events from the Health Sciences Library in our monthly newsletter for August 2019.


Review Of Pediatric Care Online, Terri Gotschall Jul 2019

Review Of Pediatric Care Online, Terri Gotschall

Faculty Scholarship and Creative Works

This guide to scholarly activities provides early- and mid-career health sciences librarians with a path to immersing in scholarly activities. The four levels walk librarians through increasing stages of scholarship. Early-career librarians will begin at the first level, navigating from discovering mentors and areas of research interest to level two, publishing a resource or book review and finding their first public speaking opportunity. More experienced librarians will find where they are on the path and continue to build their scholarship all the way to conducting and publishing original research and becoming leaders in their field.


The Impact Of Epigallocatechin-3-Gallate (Egcg) On Ts65dn Down Syndrome Mouse Models, Nicole Santana Jun 2019

The Impact Of Epigallocatechin-3-Gallate (Egcg) On Ts65dn Down Syndrome Mouse Models, Nicole Santana

The Pegasus Review: UCF Undergraduate Research Journal

Down syndrome (DS) is caused by the trisomy 21 genetic disorder, which produces a unique craniofacial phenotype. The purpose of this research is to better understand how Epigallocatechin-3-gallate (ECGC) influences the development of DS craniofacial phenotypes. Ts65Dn DS mouse models have been genetically modified to have 3 copies of numerous genes found on human chromosome 21, including DYRK1A, which plays a role in bone and brain development. EGCG is a known inhibitor of Dyrk1a activity. For this study, pregnant Ts65Dn mice were treated with 200 mg/kg of ECGC twice daily on days 7 and 8 of pregnancy. It was …


Motor And Sensory Characterization Of A Mouse Model Of Charcot-Marie-Tooth Type 2o Disease, Swaran Nandini May 2019

Motor And Sensory Characterization Of A Mouse Model Of Charcot-Marie-Tooth Type 2o Disease, Swaran Nandini

Electronic Theses and Dissertations

Dynein is an essential motor protein required for the maintenance and survival of cells. Dynein forms a motor complex to carry intracellular cargoes like organelles, growth factors, peptides, and hormones along the microtubules inside the cells. In neurons, the dynein is the retrograde motor protein that moves cargoes from the neuronal tip to the neuronal soma along the length of an axon. Dynein has an established role in neuronal nuclear migration, transport of neuronal survival signals and growth factors, organelle positioning inside neurons etc. Hence, it is not very surprising that numerous mutations in dynein have been reported in association …


Factors Influencing Unmet Medical Need Among U.S. Adults: Disparities In Access To Health Services, Ahmad Khanijahani May 2019

Factors Influencing Unmet Medical Need Among U.S. Adults: Disparities In Access To Health Services, Ahmad Khanijahani

Electronic Theses and Dissertations

Inequities in access to health services has negative consequences on individual well-being, and imposes financial and emotional burden on patients, families, health care systems, and the public. Inequities engendered from differences in socioeconomic status, health insurance coverage, race, and other characteristics can engender disparities. This study aimed to identify the potential predictors of unmet medical need among the civilian noninstitutionalized U.S. adults. Inability to receive needed medical care or receiving medical care after a delay, due to the associated costs, constructed unmet medical need. This study used a four-year (2014-2017) National Health Interview Survey (NHIS) data (sample size: 296,301 adults) …


Readability Of Patient-Reported Outcome Measures For Persons With Aphasia, Sara Gray May 2019

Readability Of Patient-Reported Outcome Measures For Persons With Aphasia, Sara Gray

Electronic Theses and Dissertations

The relationship between positive health outcomes in persons with aphasia (PWA) and personcentered care is highlighted by personally relevant information obtained directly from the PWA. Such is often facilitated via patient reported outcome measures (PROMs). In order to provide accurate responses to PROMs, PWAs must to read, comprehend, formulate and generate answers to a variety of questions. PROMs designed for other clinical populations assessed/treated by speech-language pathologists have been found to be largely unreadable. Despite the significant role of PROMs in assessment and management of aphasia, no study to date has examined the readability of these measures. Four readability formulae …


Implementation Of The Roles And Responsibilities Of Speech Language Pathologists In The Schools, Tamar Nir May 2019

Implementation Of The Roles And Responsibilities Of Speech Language Pathologists In The Schools, Tamar Nir

Electronic Theses and Dissertations

The purpose of this study was to determine how the roles and responsibilities of speech-language pathologists (SLPs) in schools are being implemented, whether speech-language pathologists in schools feel comfortable with their roles, and whether they are willing to engage in professional learning activities to hone knowledge and skills in role areas in order to inform pre-service and in-service learning This study utilized an online survey to collect responses. The survey included questions related to the rate of implementation, comfort level, and desire for further professional learning with regards to the roles and responsibilities prescribed by American Speech-Language Hearing Association (ASHA) …


A Deep Learning Approach To Diagnosing Schizophrenia, Justin Barry May 2019

A Deep Learning Approach To Diagnosing Schizophrenia, Justin Barry

Electronic Theses and Dissertations

In this article, the investigators present a new method using a deep learning approach to diagnose schizophrenia. In the experiment presented, the investigators have used a secondary dataset provided by National Institutes of Health. The aforementioned experimentation involves analyzing this dataset for existence of schizophrenia using traditional machine learning approaches such as logistic regression, support vector machine, and random forest. This is followed by application of deep learning techniques using three hidden layers in the model. The results obtained indicate that deep learning provides state-of-the-art accuracy in diagnosing schizophrenia. Based on these observations, there is a possibility that deep learning …


The Scoop, Vol. 6 Issue 2, May 2019, Health Sciences Library May 2019

The Scoop, Vol. 6 Issue 2, May 2019, Health Sciences Library

Volume 6

Latest news and events from the Health Sciences Library in our monthly newsletter for May 2019.


The Scoop, Vol. 6 Issue 1, April 2019, Health Sciences Library Apr 2019

The Scoop, Vol. 6 Issue 1, April 2019, Health Sciences Library

Volume 6

Latest news and events from the Health Sciences Library in our monthly newsletter for April 2019.


An Evaluation Of Mobile Applications For Improving Health In Older Adults: A Review Of The Literature, Patrick Healy Mar 2019

An Evaluation Of Mobile Applications For Improving Health In Older Adults: A Review Of The Literature, Patrick Healy

The Pegasus Review: UCF Undergraduate Research Journal

There are over one million mobile applications or "apps" available for use in improving health. One population that could potentially benefit from the use of mobile applications is the elderly. Choosing appropriate applications can be daunting, however, and there is a paucity of research identifying which applications are useful for elderly patients. The aim of this study is to perform a literature review regarding the available mobile applications for health and fitness and to provide health care providers with evidence-based information about other potentially useful and novel applications for their older patients.

In an attempt to address the need for …


The Scoop, Vol. 5 Issue 12, March 2019, Health Sciences Library Mar 2019

The Scoop, Vol. 5 Issue 12, March 2019, Health Sciences Library

Volume 5

Latest news and events from the Health Sciences Library in our monthly newsletter for March 2019.


The Scoop, Vol. 5 Issue 11, February 2019, Health Sciences Library Feb 2019

The Scoop, Vol. 5 Issue 11, February 2019, Health Sciences Library

Volume 5

Latest news and events from the Health Sciences Library in our monthly newsletter for February 2019.


The Scoop, Vol. 5 Issue 10, January 2019, Health Sciences Library Jan 2019

The Scoop, Vol. 5 Issue 10, January 2019, Health Sciences Library

Volume 5

Latest news and events from the Health Sciences Library in our monthly newsletter for January 2019.


Factors Influencing Nurse Practitioners' Weight Management Practices In Primary Care, Suzanne Hyer Jan 2019

Factors Influencing Nurse Practitioners' Weight Management Practices In Primary Care, Suzanne Hyer

Electronic Theses and Dissertations

More American adults are overweight or obese than ever before. Nurse practitioners (NPs) play a critical and expanding role in primary care, which is an ideal setting for the assessment and management of weight loss. NPs can make a significant contribution to tackling the obesity crisis. The study presented here seeks to close the gap in data related to how NPs approach weight management with their primary care patients. This study focused on a comprehensive examination of the current practice patterns of NPs related to weight management, a theoretical concept analysis of weight bias among healthcare providers, along with the …


Predictors Of Hospital Quality And Efficiency, Hoda Fotovvat Jan 2019

Predictors Of Hospital Quality And Efficiency, Hoda Fotovvat

Electronic Theses and Dissertations

American hospitals have made serious efforts to implement and expand their health information technology capabilities and to integrate different specialized care or high-tech services in order to maximize the efficiency and quality of care. In providing a variety of HIT-related services, these hospitals expanded their national reputation in line with integrated care goals. As a result, hospitals are encouraged to establish effective communication channels to facilitate patient-physician sharing of the patient care experience, to enhance effective pain management, and to transform patient-centered care modalities to solidify the adequacy of patient care processes. By analyzing national data sets publicly available, this …


Motivational Factors And Barriers Affecting Seniors' Decision To Relocate To A Senior Living Facility, Suja Chaulagain Jan 2019

Motivational Factors And Barriers Affecting Seniors' Decision To Relocate To A Senior Living Facility, Suja Chaulagain

Electronic Theses and Dissertations

This study aimed to explore factors affecting seniors' intention to relocate to a senior living facility. More specifically, the purpose of this study was to examine the influence of push and pull motivational factors and perceived barriers on seniors' intention to relocate to a senior living facility (SLF). In addition, the mediating role of perceived barriers on the relationships between push motivational factors and intention to relocate and pull motivational factors and intention to relocate were explored. The data of the study was collected from 363 seniors. Structural equation modeling (SEM) analysis was conducted to test the study hypotheses. The …


Ab Toxins: Recovery From Intoxication And Relative Potencies, Patrick Cherubin Jan 2019

Ab Toxins: Recovery From Intoxication And Relative Potencies, Patrick Cherubin

Electronic Theses and Dissertations

AB-type protein toxins have a catalytic A subunit attached to a cell-binding B subunit. Ricin, Shiga toxin (Stx), exotoxin A, and diphtheria toxin are AB toxins that act within the host cytosol and kill the host cell through pathways involving the inhibition of protein synthesis. Our overall goal is to help elucidate the cellular basis of intoxication for therapeutic development. According to the current model of intoxication, the effect of AB toxins is irreversible. To test this model, we developed a system that uses flow cytometry and a fluorescent reporter to examine the cellular potency of toxins that inhibit protein …


Unraveling Pdi And Its Interaction With Ab Toxins, Jessica Guyette Jan 2019

Unraveling Pdi And Its Interaction With Ab Toxins, Jessica Guyette

Electronic Theses and Dissertations

Protein disulfide isomerase (PDI) is an essential endoplasmic reticulum (ER) protein that acts as both an oxidoreductase and chaperone. It exhibits substantial flexibility and undergoes cycles of unfolding and refolding in its interaction with cholera toxin (Ctx), which is a unique property of PDI. This unfolding allows PDI to disassemble the Ctx holotoxin, which is required for Ctx activity. Here, we investigated the unfolding and refolding property of PDI and how this affects its interaction with bacterial toxins. PDI showed remarkable redox-linked conformational resilience that allows it to refold after being thermally stressed. Deletion constructs of PDI showed that both …


Modeling Disease Impact Of Vibrio-Phage Interactions, Christopher Botelho Jan 2019

Modeling Disease Impact Of Vibrio-Phage Interactions, Christopher Botelho

Electronic Theses and Dissertations

Since the work of John Snow, scientists and medical professionals have understood that individuals develop cholera by means of consuming contaminated water. Despite the knowledge of cholera's route of infection, many countries have experienced and still experience endemic cholera. Cholera is caused by the Vibrio cholerae (V. cholerae) bacterium and presents with acute diarrhea and vomiting. If untreated, infected individuals may die due to dehydration. Cholera is a disease that most commonly affects countries with poor infrastructure and water sanitation. Despite efforts to control cholera in such countries, the disease persists. One such example is Haiti which has been experiencing …


A Complete Approach To Predict Biodistribution Of Nanomaterials Within Animal Species From In-Vitro Data, Edward Price Jan 2019

A Complete Approach To Predict Biodistribution Of Nanomaterials Within Animal Species From In-Vitro Data, Edward Price

Electronic Theses and Dissertations

Smart drug-design for antibody and nanomaterial-based therapies allows for optimization of drug efficacy and more efficient early-stage pre-clinical trials. The ideal drug must display maximum efficacy at target tissue sites, but to track and predict distribution to these sites, one must have a mechanistic understanding of the kinetics involved with the individual cells of the tissue itself. This process can be tracked through biological simulations coupled with in-vitro approaches, which result in a rapid and efficient in-depth understanding of drug transport within tissue vasculature and cellular environment. As a result, it becomes possible to predict drug biodistribution within live animal …


Deaf Mis-Interpretation During Hurricane Irma: A Case Study And Evaluation, Sherilyn D. Burris Jan 2019

Deaf Mis-Interpretation During Hurricane Irma: A Case Study And Evaluation, Sherilyn D. Burris

International Crisis and Risk Communication Conference

In 2017, Manatee County Government (Florida, USA) used an untrained sign language interpreter during a media briefing on Hurricane Irma evacuation orders. The individual signed incorrectly, resulting in confusion for the community and embarrassment for the organization. This case study presents the background of accessible information in crisis management -- why and how disaster preparedness information is interpreted for the deaf community; provides the event's consequences, as well as local and global implications; and discusses ways to incorporate deaf and hard-of-hearing stakeholders and groups into existing structures and programs.


What Influences Our Decision To Vaccinate? The Social Amplification Of Risk Framework And Vaccination, Laura B. Carper Jan 2019

What Influences Our Decision To Vaccinate? The Social Amplification Of Risk Framework And Vaccination, Laura B. Carper

International Crisis and Risk Communication Conference

The current study applies the social amplification risk framework to the anti-vaccination movement, specifically to the social factors that influence the likelihood to vaccinate. A total of 264 participants were recruited using Amazon’s Mechanical Turk engine and students from a large southern university. Participants responded to questions about their personal, friend, and family experiences with vaccines, their discussion about vaccines, and trust in vaccine literature (CDC, Facebook, family, etc.). Lastly, participants responded to a modified Duke’s social support scale. Results indicated that the likelihood to vaccinate is impacted by several social factors and that those factors can be amplified based …


The Role Of Risk Tolerance In Publics’ Health Risk Perception And Responses, Hyoyeun Jun, Yen-I Lee Jan 2019

The Role Of Risk Tolerance In Publics’ Health Risk Perception And Responses, Hyoyeun Jun, Yen-I Lee

International Crisis and Risk Communication Conference

To better understand how uncertainty influences publics’ risk perception and responses, this study introduced risk tolerance as a new concept to public relations literature and then investigated how publics react to health risks with different temporal distances: climate change and foodborne illness. Through an online survey, this study found out that uncertainty, induced by risk temporal distance, leads to varied risk tolerance, which subsequently influences where and how people seek and share risk information.