Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Medical Sciences (1029)
- Nursing (536)
- Public Health (417)
- Medical Humanities (290)
- Dentistry (223)
-
- Optometry (84)
- Neurosciences (33)
- Life Sciences (16)
- Epidemiology (11)
- Medical Specialties (10)
- Oncology (7)
- Social and Behavioral Sciences (6)
- Biomedical Engineering and Bioengineering (5)
- Engineering (5)
- Rehabilitation and Therapy (4)
- Physical Sciences and Mathematics (3)
- Occupational Therapy (2)
- Pathology (2)
- Physical Therapy (2)
- Arts and Humanities (1)
- Bioinformatics (1)
- Biology (1)
- Biostatistics (1)
- Cellular and Molecular Physiology (1)
- Education (1)
- Environmental Health (1)
- Genetics and Genomics (1)
- Immunology and Infectious Disease (1)
- Microbiology (1)
- Keyword
-
- Doctor of Philosophy (PhD) Heersink School of Medicine (961)
- Doctor of Science in Nursing (DSN) School of Nursing (378)
- Doctor of Philosophy (PhD) School of Public Health (199)
- Doctor of Philosophy (PhD) School of Health Professions (153)
- Doctor of Public Health (DrPH) School of Public Health (127)
-
- Doctor of Philosophy (PhD) School of Nursing (121)
- Executive Doctor of Science (DSc) School of Health Professions (96)
- Master of Science (MS) School of Dentistry (89)
- Master of Science in Dentistry (MScD) School of Dentistry (62)
- Doctor of Philosophy (PhD) School of Optometry (58)
- Master of Dentistry (MDent) School of Dentistry (47)
- Obesity (41)
- UAB (39)
- Master of Science in Public Health (MSPH) School of Public Health (32)
- Mitochondria (31)
- Cancer (28)
- Master of Science (MS) School of Health Professions (27)
- Research (27)
- Inflammation (26)
- Undergraduate (26)
- HIV (25)
- Master of Science (MS) Heersink School of Medicine (25)
- Master of Science (MS) School of Public Health (21)
- African American (19)
- Aging (19)
- Epigenetics (19)
- Master of Science (MS) School of Optometry (19)
- Metabolism (19)
- Breast cancer (18)
- Metastasis (18)
- Publication Year
- Publication
- Publication Type
Articles 601 - 630 of 3145
Full-Text Articles in Medicine and Health Sciences
Study Of The Effects Of Contusion Spinal Cord Injury And Optogenetic Stimulation On Lower Urinary Tract Function, Salvador A. Lopez
Study Of The Effects Of Contusion Spinal Cord Injury And Optogenetic Stimulation On Lower Urinary Tract Function, Salvador A. Lopez
All ETDs from UAB
Lower urinary tract (LUT) dysfunction is a detrimental ailment that negatively affects a person’s independence, health, and overall quality of life. More specifically, LUT dysfunction as a result of spinal cord injury (SCI) is seen in more than 17,000 cases per year and of those cases, <20% are discharged from care with normal micturition1. Initially, after SCI, there is an acute period of spinal shock when the urinary bladder is flaccid and underactive, while the external urethral sphincter (EUS) that constricts the bladder outlet quickly becomes tonically active. In days to weeks after injury, spinallymediated, reflex bladder contractions re-emerge2-4. Numerous studies have examined aspects of LUT function using various models of SCI, primarily utilizing complete transection injuries. This set of studies first examined the effect of moderate to severe midthoracic contusion SCI on LUT function by examining cystometrogram (CMG) and EUS recordings, bladder/spinal cord morphology, sensory innervation of bladder tissue, and spinal neuronal activation in female mice. This model of SCI produced significant changes in normal bladder function as well as altered bladder morphology, including a robust loss of bladder afferent nerve fibers necessary for micturition. Inhibition of histone deacetylase 6 (HDAC6) has been shown to prevent the loss of sensory nerve fibers in mouse hind paw tissue5, thus HDAC6 inhibition was examined as a possible strategy to prevent the observed loss of sensory nerve fibers in bladder tissue post-SCI. iv Mice were treated using intraperitoneal injections of inhibiting compounds ACY-1083 (10 mg/kg) or Tubacin (5 mg/kg). Treatment resulted in significant improvements in CMG measures and sensory innervation of the bladder wall. Finally, optogenetic stimulation was examined using an adenoassociated virus containing cre-recombinase for cre-dependent expression of channelrhodopsin (ChR2) in both spinal intact and SCI mice. The ability to spare afferent axons in bladder tissue post-SCI through HDAC6 inhibition allowed ChR2 expression in sensory nerve fibers. Direct photostimulation of the bladder using various parameters of duration (1, 2, 5, 10 sec continuous stimulation) and power (0.1mW/mm2, 0.95mW/mm2, 6.50mW/mm2) resulted in the ability to control bladder contractions in both spinal intact (SI) and SCI animals, allowing for on-demand voiding post-injury.
The Role Of Nitric Oxide And Cyclic Guanosine Monophosphate Signaling In Arteriovenous Fistula Maturation, Maheshika S. Somarathna
The Role Of Nitric Oxide And Cyclic Guanosine Monophosphate Signaling In Arteriovenous Fistula Maturation, Maheshika S. Somarathna
All ETDs from UAB
Vascular access is the single most important component of the hemodialysis procedure and the arteriovenous fistula (AVF) is the most preferred type. However, 60% of AVFs created fail to mature successfully for dialysis use (AVF maturation failure). AVF maturation failure is primarily the result of 1) intimal hyperplasia formation (IH) and 2) poor vascular outward remodeling. Currently, a major unmet clinical need in the field is the lack of effective therapies to treat/prevent AVF maturation failure due to the poor understanding of molecular mechanisms. This proposal is designed to: 1) elucidate the pathologic significance of nitric oxide (NO) and cyclic …
The Role Of The Bone Marrow Microenvironment In Flt3-Itd Acute Myeloid Leukemia Stem Cell Resistance To Flt3 Inhibition, Nicholas R. Anderson
The Role Of The Bone Marrow Microenvironment In Flt3-Itd Acute Myeloid Leukemia Stem Cell Resistance To Flt3 Inhibition, Nicholas R. Anderson
All ETDs from UAB
Acute myeloid leukemia (AML) is an aggressive, complex hematological malignancy. AML cases with constitutively-activating internal tandem duplications in the Flt3 receptor (Flt3-ITD) represent a distinct subtype of disease with poor prognosis, but unique opportunities for targeted therapy. Flt3-specific tyrosine kinase inhibitors (TKI) have entered clinical practice due to their ability to induce remissions in a large proportion of Flt3-mutant AML patients, but their long-term efficacy remains limited due to the persistence of leukemia stem cells (LSC) in the bone marrow (BM). Herein, we outline the importance of the bone marrow microenvironment (BMM) in harboring LSC through AML development and drug …
Defining Genetic Underpinnings Of Cellular Diversity And Vulnerability In The Context Of Parkinson's Disease, Stephanie M. Boas
Defining Genetic Underpinnings Of Cellular Diversity And Vulnerability In The Context Of Parkinson's Disease, Stephanie M. Boas
All ETDs from UAB
of ALL survivors are at risk for reduced functional outcomes, and these outcomes may be more strongly related to executive functioning than neighborhood-specific variables or IEP support. Long-term goals include translating findings into practice to remediate adaptive or academic difficulties in ALL survivors.
The Difference In Fracture Strength Of Translucent Zirconia (5y-Z) Using Different Cements And Surface Treatments, Esra Elamin
The Difference In Fracture Strength Of Translucent Zirconia (5y-Z) Using Different Cements And Surface Treatments, Esra Elamin
All ETDs from UAB
Statement of Problem: With the recent advent of translucent and ultra-translucent zirconia, it is unknown if this type of high-strength ceramic restoration requires adhesive cementation to enhance retention as well as the effect of surface treatment thus its clinical applicability requires further investigation. Purpose: To investigate the difference in fracture strength of translucent zirconia (5Y-Z) using different crown thickness, different cements under different surface treatment conditions. Materials and Methods: The experimental design consisted of five groups of 30 specimens each. Two different cements were utilized under different surface treatment conditions. Copings of (1.0 mm) uniform thickness were milled of 3Y-zirconia …
Shying Away From The Shot: A Qualitative Analysis On Vaccine Hesitancy At Uab Huntsville Family Medicine Clinic, Nadia Anabtawi, Roger D. Smalligan, Gayatri Venkatraman
Shying Away From The Shot: A Qualitative Analysis On Vaccine Hesitancy At Uab Huntsville Family Medicine Clinic, Nadia Anabtawi, Roger D. Smalligan, Gayatri Venkatraman
UAB Huntsville Research Day - All Presentations
2022 oral presentation
Balance In The Force: The Fine Line Of Immunosuppression In Hospitalized Patients With Covid-19 Infection And Common Variable Immunodeficiency, Jeremy Brozyna, Holman Li, Ali Hassoun, Farrah Ibrahim
Balance In The Force: The Fine Line Of Immunosuppression In Hospitalized Patients With Covid-19 Infection And Common Variable Immunodeficiency, Jeremy Brozyna, Holman Li, Ali Hassoun, Farrah Ibrahim
UAB Huntsville Research Day - All Presentations
2022 oral presentation
A Rare Case Of Late-Presenting Congenital Diaphragmatic Hernia (Cdh) Complicated By Postoperative Renal Infarction, Andrew Canto, Adam Bonner, Zaria Murrell
A Rare Case Of Late-Presenting Congenital Diaphragmatic Hernia (Cdh) Complicated By Postoperative Renal Infarction, Andrew Canto, Adam Bonner, Zaria Murrell
UAB Huntsville Research Day - All Presentations
2022 oral presentation
Persistent Abdominal Pain Reveals Recurrent Intussusception With An Enclosed Lymphoma, Aubriana Smith
Persistent Abdominal Pain Reveals Recurrent Intussusception With An Enclosed Lymphoma, Aubriana Smith
UAB Huntsville Research Day - All Presentations
2022 oral presentation
The Utility Of Thrombophilia Panels Prior To Microvascular Surgery, S Drummond, O Olaleye, E Soto, R J. Fix, J May, P Patcha
The Utility Of Thrombophilia Panels Prior To Microvascular Surgery, S Drummond, O Olaleye, E Soto, R J. Fix, J May, P Patcha
UAB Huntsville Research Day - All Presentations
2022 research poster
Covid Induced Hlh, Adam Bonner, Farrah Ibrahim, Imamuddin Mohammed
Covid Induced Hlh, Adam Bonner, Farrah Ibrahim, Imamuddin Mohammed
UAB Huntsville Research Day - All Presentations
2022 clinical vignette poster
A Wink Should Make You Think: Pancoast Syndrome From Superimposed Infection Overlying An Apical Lung Malignancy, Adam Bonner, Sydney Blankenship, Alan Baggett
A Wink Should Make You Think: Pancoast Syndrome From Superimposed Infection Overlying An Apical Lung Malignancy, Adam Bonner, Sydney Blankenship, Alan Baggett
UAB Huntsville Research Day - All Presentations
2022 clinical vignette poster
An Uncommon Cause Of Stroke: A Case Report Of Meningovascular Neurosyphilis, Joshua Derbort, Eman Alshaikh, Tarun Kukkadapu, Nessy Phillip
An Uncommon Cause Of Stroke: A Case Report Of Meningovascular Neurosyphilis, Joshua Derbort, Eman Alshaikh, Tarun Kukkadapu, Nessy Phillip
UAB Huntsville Research Day - All Presentations
2022 clinical vignette poster
Diagnostic And Treatment Dilemma In Low Ses Patient With Hiv And An Aids Defining Illness, Payton Garlington, Melissa Ruck, Kelsey Ivey
Diagnostic And Treatment Dilemma In Low Ses Patient With Hiv And An Aids Defining Illness, Payton Garlington, Melissa Ruck, Kelsey Ivey
UAB Huntsville Research Day - All Presentations
2022 clinical vignette poster
A Rare Presentation Of Acute Acalculous Cholecystitis In A Patient With Acute Hepatitis A, Oseyime Okoeguale, Rafik Elbeblawy, Jimmy Molyneux, Roger Smalligan
A Rare Presentation Of Acute Acalculous Cholecystitis In A Patient With Acute Hepatitis A, Oseyime Okoeguale, Rafik Elbeblawy, Jimmy Molyneux, Roger Smalligan
UAB Huntsville Research Day - All Presentations
2022 clinical vignette poster
I Can See Your Halo: Recognizing A Halo Scalp Ring, Jake Picicci, Erik Henninger
I Can See Your Halo: Recognizing A Halo Scalp Ring, Jake Picicci, Erik Henninger
UAB Huntsville Research Day - All Presentations
2022 clinical vignette poster
Metabolic Syndrome In A Case Of Acute Intermittent Porphyria (Aip), Rafik Elbeblawy
Metabolic Syndrome In A Case Of Acute Intermittent Porphyria (Aip), Rafik Elbeblawy
UAB Huntsville Research Day - All Presentations
2022 oral presentation
Marijuana Variant Of Concern: Delta 8-Tetrahydrocannabinol (Delta-8-Thc, Δ8-Thc), Mack E. Bozman, Senthil Vel Rajan Rajaram Manoharan, Tarak Vasavada
Marijuana Variant Of Concern: Delta 8-Tetrahydrocannabinol (Delta-8-Thc, Δ8-Thc), Mack E. Bozman, Senthil Vel Rajan Rajaram Manoharan, Tarak Vasavada
UAB Huntsville Research Day - All Presentations
2022 clinical vignette poster
Membranoproliferative Glomerulonephritis With Monoclonal Igg Deposits, Jennifer Lamar, Leela Kantamneni, Farrah Ibrahim
Membranoproliferative Glomerulonephritis With Monoclonal Igg Deposits, Jennifer Lamar, Leela Kantamneni, Farrah Ibrahim
UAB Huntsville Research Day - All Presentations
2022 oral presentation
Case Presentation: Abdominal Pain, Caitlyn Tomblin, Jesse Faulk
Case Presentation: Abdominal Pain, Caitlyn Tomblin, Jesse Faulk
UAB Huntsville Research Day - All Presentations
2022 oral presentation
Manly Man Nearly Kicks The Can: Testosterone Supplementation Induced Polycythemia In Acute Cva, Jesse Zheng, Alan Baggett
Manly Man Nearly Kicks The Can: Testosterone Supplementation Induced Polycythemia In Acute Cva, Jesse Zheng, Alan Baggett
UAB Huntsville Research Day - All Presentations
2022 oral presentation
Microrna Correlates Of Childhood Maltreatment And Suicidality, Clinton Martin, Janaki Nimmagadda, Anupama Yedla, Richard Shelton, Yogesh Dwivedi, Matthew Bonds
Microrna Correlates Of Childhood Maltreatment And Suicidality, Clinton Martin, Janaki Nimmagadda, Anupama Yedla, Richard Shelton, Yogesh Dwivedi, Matthew Bonds
UAB Huntsville Research Day - All Presentations
2022 research poster
Evaluating Clinical Outcomes Of Tranexemic Acid Administration In Cranial Vault Reconstruction For Craniosynostosis, P White, E Soto, A R. Clark, J Lepard, J Johnston, K Niedermeier, C J. Rozelle, J H. Grant, R P. Myers
Evaluating Clinical Outcomes Of Tranexemic Acid Administration In Cranial Vault Reconstruction For Craniosynostosis, P White, E Soto, A R. Clark, J Lepard, J Johnston, K Niedermeier, C J. Rozelle, J H. Grant, R P. Myers
UAB Huntsville Research Day - All Presentations
2022 research poster
Evaluating Microsurgical Pedicle Lengthening In Free Tissue Transfer, A Review Of The Literature, Anthony Wilson, Edgar Soto, Sharon D. Lawson, Ali Kilic, René P. Myers, Jorge I. De La Torre
Evaluating Microsurgical Pedicle Lengthening In Free Tissue Transfer, A Review Of The Literature, Anthony Wilson, Edgar Soto, Sharon D. Lawson, Ali Kilic, René P. Myers, Jorge I. De La Torre
UAB Huntsville Research Day - All Presentations
2022 research poster
An Unusual Presentation Of Alpha-1 Antitrypsin Deficiency, Khalid Ameen, Anthony Wilson, Farrah Ibrahim
An Unusual Presentation Of Alpha-1 Antitrypsin Deficiency, Khalid Ameen, Anthony Wilson, Farrah Ibrahim
UAB Huntsville Research Day - All Presentations
2022 clinical vignette poster
Infected Native Aortic Valve Aneurysm In A Patient With Streptococcus Viridans Infective Endocarditis, Khalid Ameen, Maha Al-Baghdadi, John Fanning
Infected Native Aortic Valve Aneurysm In A Patient With Streptococcus Viridans Infective Endocarditis, Khalid Ameen, Maha Al-Baghdadi, John Fanning
UAB Huntsville Research Day - All Presentations
2022 clinical vignette poster
A Case Of Postural Orthostatic Tachycardia Syndrome And Anxiety, Nadia Anabtawi, Clinton Martin, Janaki Nimmagadda, Richard Shelton
A Case Of Postural Orthostatic Tachycardia Syndrome And Anxiety, Nadia Anabtawi, Clinton Martin, Janaki Nimmagadda, Richard Shelton
UAB Huntsville Research Day - All Presentations
2022 clinical vignette poster
A Rare Case Of Hemophagocytic Lymphohistiocytosis (Hlh), Lauren Beggs, Dyan Alvarez Dupaya, Farrah Ibrahim, Katie Glosemeyer
A Rare Case Of Hemophagocytic Lymphohistiocytosis (Hlh), Lauren Beggs, Dyan Alvarez Dupaya, Farrah Ibrahim, Katie Glosemeyer
UAB Huntsville Research Day - All Presentations
2022 clinical vignette poster
A Case Of Hepatocellular Carcinoma (Hcc) Presenting With Peritoneal Metastasis (Pm), Rafik Elbeblawy, Christopher Terrell, Farrah Ibrahim, Ali Hachem
A Case Of Hepatocellular Carcinoma (Hcc) Presenting With Peritoneal Metastasis (Pm), Rafik Elbeblawy, Christopher Terrell, Farrah Ibrahim, Ali Hachem
UAB Huntsville Research Day - All Presentations
2022 clinical vignette poster
Human Immunodeficiency Virus (Hiv) Infection Presenting With Progressive Rash, Rafik Elbeblawy, Christopher Terrell, Nate Moore, Ali Hassoun
Human Immunodeficiency Virus (Hiv) Infection Presenting With Progressive Rash, Rafik Elbeblawy, Christopher Terrell, Nate Moore, Ali Hassoun
UAB Huntsville Research Day - All Presentations
2022 clinical vignette poster