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Adenosine And Autism: A Spectrum Of Opportunities [Post-Print], Susan A. Masino, Masahito Kawamura Jr., Jessica Cote, Rebecca Williams, David N. Ruskin

Faculty Scholarship

In rodents, insufficient adenosine produces behavioral and physiological symptoms consistent with several comorbidities of autism. In rodents and humans, stimuli postulated to increase adenosine can ameliorate these comorbidities. Because adenosine is a broad homeostatic regulator of cell function and nervous system activity, increasing adenosine's influence might be a new therapeutic target for autism with multiple beneficial effects.