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Optimizing Your Capstone Experience: A Guidebook For Allied Health Professionals, Virginia E. Koenig

Open Touro Created

This guidebook is designed for allied health professional students. Each chapter in this guidebook provides students with useful information, tools, and examples that will support them before, during, and after their capstone journey. This is a one of a kind resource that can be used in a variety of professional academic settings. The primary goal of this guidebook is to support students throughout their capstone experience and to help them understand how the capstone process will enrich both their personal and professional advancement.

Are Workflow Interruptions A Hindrance Stressor? The Moderating Effect Of Time-Management Skill, Jie (Yonas) Ma, Amy M. Kerulis, Yanxia Wang, Aditi Rabindra Sachdev

The School of Health Sciences Publications and Research

Workflow interruptions are a pervasive job stressor detrimental to employee job performance and wellbeing. Previous studies noted that the detrimental effect was intervened by increased job demands (i.e., demand accumulation mechanism). Yet, little attention has been paid to employees’ stressor appraisal, a critical mechanism of stress process from transactional perspective. Moreover, we lack of knowledge about what malleable, action-based coping strategies can reduce the negative effect of workflow interruptions. To address these limitations, we collected data from a sample of IT professionals using a 5-day daily diary design. With 330 daily observations from 75 employees, the findings revealed that by …

Depression Among Epileptic Patients And Its Association With Drug Therapy In Sub-Saharan Africa: A Systematic Review And Meta-Analysis., Getenet Dessie, Henok Mulugeta, Cheru Tesema Leshargie, Fasil Wagnew, Sahai Burrowes

BACKGROUND: Despite the high prevalence of epilepsy in sub-Saharan Africa and the established relationship between depression and epilepsy, the extent of comorbid epilepsy and depression in the region is still poorly understood. The objective of this systematic review and meta-analysis is to address this gap in the literature by determining the pooled prevalence of depression among epileptic patients in sub-Saharan Africa.

METHODS: A systematic desk review and electronic web-based search of PubMed, Google Scholar, EMBASE, PsycINFO and the World Health Organization's Hinari portal (which includes the SCOPUS, African Index Medicus, and African Journals Online databases) conducted from December 2, 2017 …

Change In Brain Volume And Cortical Thickness After Behavioral And Surgical Weight Loss Intervention, Cara Bohon, Allan Geliebter

Lander College of Arts and Sciences Publications and Research

Obesity is associated with reduced cortical thickness and brain volume, which may be related to poor nutrition. Given that brain atrophy in anorexia nervosa recovers with nutritional improvements and weight gain, it is worth examining how brain structure changes at the other end of the weight spectrum with weight loss. Thus, this study aimed to examine change in cortical thickness and brain volume in 47 patients with severe obesity who participated in no treatment, behavioral weight loss, or bariatric surgery. T1-weighted MRI scans were conducted pre-treatment and approximately four months later. Measures of cortical thickness, gray matter volume, and white …

A Randomized Controlled Dosing Study Of Iyengar Yoga And Coherent Breathing For The Treatment Of Major Depressive Disorder: Impact On Suicidal Ideation And Safety Findings, Maren Nyer, Patricia Gerbarg, Marisa M. Silveri, Jennifer Johnston, Tammy M. Scott, Maya Nauphal, Liz Owen, Greylin H. Nielsen, David Mischoulon, Richard P. Brown, Maurizio Fava, Chris C. Streeter

NYMC Faculty Publications

BACKGROUND: Yoga interventions offer promise for the treatment of major depressive disorder (MDD), yet their safety and potential impact on suicidal ideation (SI) have not been well documented. This study evaluated the safety of a randomized controlled dose-finding trial of Iyengar yoga plus coherent breathing for individuals with MDD, as well as the potential effects of the intervention on SI without intent. METHODS: Participants with Beck Depression Inventory-II (BDI-II) scores >/=14 and a diagnosis of MDD (using DSM-IV criteria) were randomized to either a low dose group (LDG) or high dose group (HDG) and received a 12-week manualized intervention. The …

Nyx-2925 Is A Novel Nmda Receptor-Specific Spirocyclic-Beta-Lactam That Modulates Synaptic Plasticity Processes Associated With Learning And Memory, M. Amin Khan, David R. Houck, Amanda L. Gross, Xiao-Lei Zhang, Cassia Cearley, Patric K. Stanton, Joseph R. Moskal

NYMC Faculty Publications

Background: N-methyl-D-aspartate receptors are one member of a family of ionotropic glutamate receptors that play a pivotal role in synaptic plasticity processes associated with learning and have become attractive therapeutic targets for diseases such as depression, anxiety, schizophrenia, and neuropathic pain. NYX-2925 ((2S, 3R)-3-hydroxy-2-((R)-5-isobutyryl-1-oxo-2,5-diazaspiro[3.4]octan-2-yl)butanamide) is one member of a spiro-beta-lactam-based chemical platform that mimics some of the dipyrrolidine structural features of rapastinel (formerly GLYX-13: threonine-proline-proline-threonine) and is distinct from known N-methyl-D-aspartate receptor agonists or antagonists such as D-cycloserine, ketamine, MK-801, kynurenic acid, or ifenprodil. Methods: The in vitro and in vivo pharmacological properties of NYX-2925 were examined. Results: NYX-2925 has …

Relationships Between Clinical Scales And Binge Eating Days In Adults With Moderate To Severe Binge Eating Disorder In Two Phase Iii Studies, Leslie L. Citrome, Judith C. Kando, Caleb Bliss

NYMC Faculty Publications

OBJECTIVES:

In two Phase III studies, lisdexamfetamine dimesylate (LDX) reduced binge eating (BE) days/week in adults with moderate to severe binge eating disorder (BED) and was associated with improvement based on the Clinical Global Impressions-Improvement (CGI-I) scale. In this study, post hoc analyses examined the relationships between clinical observations and clinical rating scales in individuals with BED.

CLINICAL TRIAL REGISTRATION:

NCT01718483 (ClinicalTrials.gov/ct2/show/NCT01718483); NCT01718509(ClinicalTrials.gov/ct2/show/NCT01718509).

METHODS:

Two 12-week, double-blind, placebo-controlled studies randomized (1:1) adults meeting Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision, BED criteria and with protocol-defined moderate to severe BED (study …

Childhood Obesity: The Role Of The Mental Health Professional, Barry Panzer

NYMC Faculty Publications

This work consists of two major components: understanding the nature of childhood obesity and providing clinical services. Factors responsible for the current epidemic will be outlined, as will the current definition of the disorder. Statistical data regarding the epidemiology of weight disorders in childhood will be provided in order to give a perspective of the problem. Various obesity trajectories and their differential diagnostic and treatment issues will be thoroughly explored. The intervention section intends to help clinicians to evaluate salient factors in assessing the obese child and to identify appropriate goals and treatment methods. The course will provide vital information …

The Correlation Between Stress And The Development Of Dissociative Identity Disorder, Aviva Soibelman

The Science Journal of the Lander College of Arts and Sciences

Stress is a huge part of life. Our body responds to stress in different ways and most of the times the body overcomes the stress. There are a few incidents when the body is not capable of dealing with the stress and the toll it takes on the brain is undeniable. One result of intolerable stress is Dissociative Identity Disorder (DID) in which biopsychology comes to life, as we see how the body is affected by psychology, and vice versa. The mediators that help the body adapt to stressors become detrimental when a person faces trauma or chronic stress. Glucocorticoids, …

Schizophrenia Relapse, Patient Considerations, And Potential Role Of Lurasidone, Leslie L. Citrome

NYMC Faculty Publications

When treating persons with schizophrenia, delaying time to relapse is a main goal. Antipsychotic medication has been the primary treatment approach, and there are a variety of different choices available. Lurasidone is a second-generation (atypical) antipsychotic agent that is approved for the treatment of schizophrenia and bipolar depression. Three long-term studies of lurasidone have examined time to relapse in persons with schizophrenia, including a classic placebo-controlled randomized withdrawal study and two 12-month active comparator studies (vs risperidone and vs quetiapine extended-release). Lurasidone 40-80 mg/d evidenced superiority over placebo (number needed to treat [NNT] vs placebo for relapse, 9). Lurasidone 40-160 …

Bupropion Induced Hyponatremia In An Elderly Patient: A Case Report And Review Of The Literature, Sahil Munjal, Yvette Smolin

NYMC Faculty Publications

We present the case of a 72-year-old female with a major depressive episode who developed hyponatremia associated with bupropion. In reviewing the literature, there are only a few case reports which pertain to this topic. The clinical symptoms of hyponatremia can be misinterpreted as a worsening of the primary psychiatric illness and can lead to potentially serious consequences if not fully evaluated. We recommend that clinicians should be well aware of this side effect and that sodium levels should be checked within the first 2 weeks after initiating treatment in patients, especially those with additional risk factors for hyponatremia, such …

Managing Agitation Associated With Schizophrenia And Bipolar Disorder In The Emergency Setting, Scott Zeller, Leslie Citrome

NYMC Faculty Publications

INTRODUCTION: Patient agitation represents a significant challenge in the emergency department (ED), a setting in which medical staff are working under pressure dealing with a diverse range of medical emergencies. The potential for escalation into aggressive behavior, putting patients, staff, and others at risk, makes it imperative to address agitated behavior rapidly and efficiently. Time constraints and limited access to specialist psychiatric support have in the past led to the strategy of "restrain and sedate," which was believed to represent the optimal approach; however, it is increasingly recognized that more patient-centered approaches result in improved outcomes. The objective of this …

First-Episode Of Synthetic Cannabinoid-Induced Psychosis In A Young Adult, Successfully Managed With Hospitalization And Risperidone, Aaron Roberto, Aileen Lorenzo, Jonathan Young, Abhishek Mohan, Subhash Pinnaka, Kyle Lapidus

NYMC Residents/Fellows Publications

Synthetic cannabinoids- (SCs-) induced psychosis is a growing public health concern. It leads to significant impairment, including emotional distress, difficulty communicating, and other debilitating symptoms. In this case report, we discuss a patient with no previous history of psychotic symptoms, presenting with first-episode psychosis in the context of progressive, acutely worsening, disorganized, psychotic thoughts and behaviors following prolonged use of SCs. We also discuss relevant literature on SCs-induced psychosis, highlighting its prevalence, presentation, diagnosis, and recommended management. It is important to diagnose and treat SCs-induced psychosis as early and efficiently as possible, in order to alleviate symptoms while limiting functional …

How Clinicians Feel About Working With Spouses Of The Chronically Ill, Douglas Ingram

NYMC Faculty Publications

Clinicians who provide psychotherapy to spouses or partners of the chronically ill were solicited through listserves of psychodynamic and other organizations. The current report excluded those therapists working with spouses of dementia patients. Interviews were conducted with clinicians who responded. The interviews highlight the challenges commonly encountered by psychotherapeutic work with this cohort of therapy patients. A comparison is drawn that shows both overlap and distinctions between the experiences of those therapists engaging with spouses of chronically ill patients without a dementing process and those working with spouses of chronically ill patients who do suffer from a dementing process.

Which Methods Of Treating Attention Deficit Hyperactive Disorder Are Most Effective And Most Closely Match Patient Lifestyle?, Yehudit Erlbaum

The Science Journal of the Lander College of Arts and Sciences

ADHD, attention deficit hyperactive disorder, is a disorder characterized by hyperactivity, inattentiveness, inability to remain on task, fidgetiness, and impulsivity. An over absorption of dopamine by the dopamine transporters leads to a lack of dopamine, the inhibiting neurotransmitter in the brain, resulting in the inability for the individual to inhibit their impulses. The disease is most likely seen in children but may continue into adulthood. The length of the disease across the individual’s life span, results in expensive treatment, whether it be medication or Cognitive Behavior Therapy, CBT. Therefore, these medical costs have caused researchers to find the most efficient …

Treating The Cognitive And Social Dysfunctions Related To Type 2 Diabetes, Joseph Indelicato

The School of Health Sciences Publications and Research

While much has been written about the effects of diabetes on cardiovascular functioning, less attention has been paid upon the role of diabetes on cognitive functioning. While researchers are still debating the pathophysiology of the cognitive dysfunction triggered by diabetes, including the possibility that Alzheimer’s being Type III diabetes, among other possibilities. Less research has targeted addressing these problems among those with diabetes. Social problems associated with having cognitive dysfunctions in diabetics, have received very little attention. Social activities are perhaps the most difficult and complicated behaviors humans engage in, Even the concept of measurable Social Intelligence comes relatively new …

Insomnia And Exacerbation Of Anxiety Associated With High-Epa Fish Oil Supplements After Successful Treatment Of Depression, Lauren B. Blanchard, Gordon C. Mccarter

Faculty Publications & Research of the TUC College of Pharmacy

A 54-year-old male consulted his general practitioner for increasing general anxiety and mild panic attacks despite effective treatment for recurrent major depressive disorder, which included a fish oil supplement enriched in eicosapentaenoic acid (EPA). The patient would awaken suddenly at night with shortness of breath and overwhelming worry. During the daytime, he felt a general, nonspecific anxiety and frequently experienced sympathetic activation upon confronting routine challenges. He also experienced dyspnea-induced feelings of panic. He reported that he stopped taking the fish oil supplements after several more months of symptoms, and his anxiety and insomnia then largely disappeared. Several weeks later, …

Off-Label Use Of Transmucosal Ketamine As A Rapidacting Antidepressant: A Retrospective Chart Review, Linda Nguyen, Patrick J. Marshalek, Cory B. Weaver, Kathy J. Cramer, Scott E. Pollard, Rae Reiko Matsumoto

Faculty Publications & Research of the TUC College of Pharmacy

Objective: This study evaluated the effectiveness and safety of subanesthetic doses of ketamine using an off-label, transmucosal administration route in patients with treatment-resistant depression.

Methods: A retrospective chart review was conducted to identify patients who met the inclusion criteria for treatment-resistant major depressive disorder. Seventeen such patients who received subanesthetic doses of ketamine were included. Patient demographics, efficacy (drug refill, clinician notes), side effects, and concurrent medications were assessed.

Results: Benefit from low-dose transmucosal ketamine was noted in 76% of subjects (average age 48 years, 88% female), with a dose duration lasting 7–14 days. No notable side …

Eating Disorders: The Hidden Hormonal Effect On Fertility, Esther Tessler-Karfunkel

The Science Journal of the Lander College of Arts and Sciences

Women who have a history of eating disorders, specifically anorexia nervosa, are more prone to suffer from infertility. There are several hormones which are the driving force in this system and are therefore responsible for this. Fortunately, there are treatments which can help women with a history of eating disorders to reproduce. Using information found on Pubmed and Touro College’s database, this paper will discuss why the body cannot reproduce when it is lacking proper nutrition, as well as the various dynamics in the human reproductive system which are compromised when the body is not properly nourished.

Altering Endoplasmic Reticulum Stress In A Model Of Blast-Induced Traumatic Brain Injury Controls Cellular Fate And Ameliorates Neuropsychiatric Symptoms, Aric Flint Logsdon, Ryan Coddington Turner, Brandon Peter Lucke-Wold, Matthew James Robson, Zachary James Naser, Kelly Elizabeth Smith, Rae Reiko Matsumoto

Faculty Publications & Research of the TUC College of Pharmacy

Neuronal injury following blast-induced traumatic brain injury (bTBI) increases the risk for neuropsychiatric disorders, yet the pathophysiology remains poorly understood. Blood-brain-barrier (BBB) disruption, endoplasmic reticulum (ER) stress, and apoptosis have all been implicated in bTBI. Microvessel compromise is a primary effect of bTBI and is postulated to cause subcellular secondary effects such as ER stress. What remains unclear is how these secondary effects progress to personality disorders in humans exposed to head trauma. To investigate this we exposed male rats to a clinically relevant bTBI model we have recently developed. The study examined initial BBB disruption using Evan’s blue (EB), …

Anorexia Nervosa: Current Research From A Biological Perspective, Udy Tropp

The Science Journal of the Lander College of Arts and Sciences

Eating disorders are viewed as serious mental illnesses, carrying significant, life-threatening medical and psychiatric implications, including morbidity and mortality. According to the Academy of Eating Disorders, anorexia nervosa has the highest mortality rate of any psychiatric disorder. The American Psychiatric Association (2004) claims that approximately three percent of the United States female population has a clinically relevant eating disorder. Risk of premature death is 6-12 times higher in women with anorexia as compared to the general population, and it has become the third most common form of chronic illness among adolescent women aged 15 to 19 years. Although the prevalence …

A Proposed Mechanism For Drug-Induced Nightmares, Isaac Brezner

The Science Journal of the Lander College of Arts and Sciences

The following is the introduction of this article: The fields of neuropharmacology and psychopharmacology are known to be highly connected, despite our severe lack of knowledge in these fields. One of the many overlaps between the two fields is sleep, which itself entails many mechanisms and events which are, as of yet, unexplainable. From the perspective of either field, one of the most mysterious events occurring during sleep is dreaming. From the cause of dreams to their content, little is known about them or their more sinister subclassification: nightmares. In this field of disturbed dreaming, neuropharmacology makes a large intrusion …

Education Chronicle Issue 4 No. 1, Touro College School Of Education And Psychology - Graduate Division

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Education Chronicle Issue 1 Number 3, Touro College School Of Education And Psychology - Graduate Division

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"An informational publication of the School of Education and Psychology - Graduate Division"

Education Chronicle Issue 1 No. 1, Touro College School Of Education And Psychology - Graduate Division

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