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Full-Text Articles in Medicine and Health Sciences

Clinical Viability Study Of Preattentive Visual Search Glaucoma, James Loughman Dec 2006

Clinical Viability Study Of Preattentive Visual Search Glaucoma, James Loughman

Doctoral

Background/Aim: Previous research has shown that several clinical conditions cause increased pre-attentive visual search (PAVS) times, implying reduced parallel search capabilities in glaucoma, DLB dementia and Parkinson’s disease. The purpose of the research reported here was two-fold • To examine for the first time the effect of a number of variables on PAVS performance including optical blur, age, retinal eccentricity and perceptual learning. Such investigations are designed to elucidate the nature of best clinical practise and to determine whether the test remains viable in the presence of such potentially confounding variables. • To analyse the efficiency of PAVS in cases …


An Event-Driven Approach To Computerizing Clinical Guidelines Using Xml, Bing Wu, Essam Mansour, Kudakwashe Dube, Jianxin Li Sep 2006

An Event-Driven Approach To Computerizing Clinical Guidelines Using Xml, Bing Wu, Essam Mansour, Kudakwashe Dube, Jianxin Li

Conference Papers

Clinical events form the basis of patient care practice. Their computerization is an important aid to the work of clinicians. Clinical guidelines or protocols direct clinicians and patients on when and how to handle clinical problems. Thus, clinical guidelines are an encapsulation of clinical events. Hence, an event-driven approach to computerizing the management of clinical guidelines is worthy of investigation. In our framework, called SpEM, the main clinical guideline management dimensions are specification, execution, and manipulation. This paper presents an event-driven approach, within the context of the SpEM framework, to manage clinical guidelines. The event-driven approach is based on the …


Newly Identified Vitamin K-Producing Bacteria Isolated From The Neonatal Faecal Flora, Gordon Cooke, John Behan, Mary Costello Sep 2006

Newly Identified Vitamin K-Producing Bacteria Isolated From The Neonatal Faecal Flora, Gordon Cooke, John Behan, Mary Costello

Articles

Fat-soluble vitamin K is an essential component of the blood clotting process. Menaquinones are the naturally occurring form of vitamin K identified in bacteria. Lipid extracts were made from three bacteria originally isolated from the human neonatal gut and identified as Enterobacter agglomerans, Serratia marcescens and Enterococcus faecium. Following preparative thin layer chromatography (TLC), the lipid extracts were subjected to liquid chromatography-mass spectrometry (LC-MS) analysis. Peak analysis of the LC-MS data showed that the three bacteria produce various forms of menaquinone.


Preliminary Results For A Monocular Marker-Free Gait Measurement System, Jane Courtney, Annraoi Depaor May 2006

Preliminary Results For A Monocular Marker-Free Gait Measurement System, Jane Courtney, Annraoi Depaor

Articles

This paper presents results from a novel monocular marker-free gait measurement system. The system was designed for physical and occupational therapists to monitor the progress of patients through therapy. It is based on a novel human motion capture method derived from model-based tracking. Testing is performed on two monocular, sagittal-view, sample gait videos – one with both the environment and the subject’s appearance and movement restricted and one in a natural environment with unrestricted clothing and motion. Results of the modelling, tracking and analysis stages are presented along with standard gait graphs and parameters.


First Report Of Genotypic Resistance To Adefovir In Chronic Hbv In The Republic Of Ireland, B. Laoi, Celine Herra, S. Norris, B. Crowley Mar 2006

First Report Of Genotypic Resistance To Adefovir In Chronic Hbv In The Republic Of Ireland, B. Laoi, Celine Herra, S. Norris, B. Crowley

Articles

No abstract provided.


Cutting Rate Effect On Temperature During Cortical Bone Sawing, Hamid Khalili Parsa, Ger Reilly, Brendan Mccormack Jan 2006

Cutting Rate Effect On Temperature During Cortical Bone Sawing, Hamid Khalili Parsa, Ger Reilly, Brendan Mccormack

Conference Papers

When bone is cut the occurrence of thermal damage to the bone is of major concern to the surgeon. If the temperature exceeds 44°C for longer than 1 min, bone repair is impaired (Eriksson et al, 1984) and necrosis may occur. Repeated use of cutting blades may reduce the cutting efficiency (Wevers et al, 1987; Toksvig-Larsen et al, 1992). Wevers et al also found that there is a greater force required to cut cortical bone using a blunt saw compared to new one.


Indentation Fracture Of Bovine Cortical Bone: Acoustic Emission Technique, Ashkan Safari, Ger Reilly, Brendan Mccormack Jan 2006

Indentation Fracture Of Bovine Cortical Bone: Acoustic Emission Technique, Ashkan Safari, Ger Reilly, Brendan Mccormack

Conference Papers

Indentation cutting may result in microcracking and main crack growth which was previously reported. In this study, we recorded the AE signals produced by cracking processes during cutting on cortical bone, measuring the cutting force and correlating between load-displacement curves and AE activities.


Potential Of Vibrational Spectroscopy In The Diagnosis Of Human Tumours., Eoghan O'Faolain Jan 2006

Potential Of Vibrational Spectroscopy In The Diagnosis Of Human Tumours., Eoghan O'Faolain

Doctoral

Just fewer than 20,000 people are annually diagnosed with some form of cancer in Ireland and one in three people are likely to contract some form of cancer by age 74. With the number of cases increasing at an annual rate of 2%, the early detection and treatment of cancer is becoming increasingly important. Both IR and Raman spectroscopy offer the potential for real time, quantitative detection of cancer and even precancer. This study investigates the potential of Raman and Fourier transform infrared, both benchtop and synchrotron spectroscopies for the detection of cervical cancer. The tissue was classified and its …


Effects Of Retinal Image Degradation On Pre-Attentive Visual Search (Pavs) Efficiency For Flicker, Movement And Orientation Stimuli, Peter Davison, James Loughman Jan 2006

Effects Of Retinal Image Degradation On Pre-Attentive Visual Search (Pavs) Efficiency For Flicker, Movement And Orientation Stimuli, Peter Davison, James Loughman

Articles

Background: Previous research has shown that several clinical conditions cause increased preattentive visual search (PAVS) times, implying reduced parallel search capabilities in glaucoma and DLB dementia. The purpose of the research reported here was to examine for the first time the resistance of PAVS to dioptric blur using targets differing from the background in terms of flicker, vertical displacement, and orientation. Resistance would enhance the applicability of PAVS as a screening method for glaucoma and other clinical conditions affecting performance of a substantial area of the retina. Method: Computer generated flicker, orientation and vertical displacement targets were used to assess …


Effects Of Retinal Image Degradation On Pre-Attentive Visual Search (Pavs) Efficiency For Flicker, Movment And Orientation Stimuli, Peter Davison, James Loughman Jan 2006

Effects Of Retinal Image Degradation On Pre-Attentive Visual Search (Pavs) Efficiency For Flicker, Movment And Orientation Stimuli, Peter Davison, James Loughman

Articles

Background: Previous research has shown that several clinical conditions cause increased pre-attentive visual search (PAVS) times, implying reduced parallel search capabilities in glaucoma and DLB dementia. The purpose of the research reported here was to examine for the first time the resistance of PAVS to dioptric blur using targets differing from the background in terms of flicker, vertical displacement, and orientation. Resistance would enhance the applicability of PAVS as a screening method for glaucoma and other clinical conditions affecting performance of a substantial area of the retina. Method: Computer generated flicker, orientation and vertical displacement targets were used to assess …


Aberrant Expression Of Light And Its Associated Receptors In Systemic Lupus Erythematosus And Coeliac Disease, Eugene Dempsey Jan 2006

Aberrant Expression Of Light And Its Associated Receptors In Systemic Lupus Erythematosus And Coeliac Disease, Eugene Dempsey

Doctoral

Members of the TNF superfamily play important roles in the development and maintenance of an effective immune response. One such member of this superfamily, LIGHT, can act as a ligand for three receptors, HVEM, LT-R and DcR3. The engagement of LIGHT and HVEM, an important secondary signal for the full activation of T cells, results in a strong Th1 type response with increased production of cytokines such as INF--. The LIGHT-LT-R pathway plays a role in the recruitment of immune cells to sites of inflammation and can induce apoptosis in certain cells. DcR3, a soluble receptor, is speculated to function …