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Full-Text Articles in Medicine and Health Sciences
Surgical Outcomes Of Extraskeletal Myxoid Chondrosarcoma, Coşkun Ulucaköy, İsmai̇l Burak Atalay, Ali̇ekber Yapar, Ahmet Yi̇ği̇t Kaptan, İzzet Bi̇ngöl, Mehmet Doğan, Mehmet Fati̇h Ekşi̇oğlu
Surgical Outcomes Of Extraskeletal Myxoid Chondrosarcoma, Coşkun Ulucaköy, İsmai̇l Burak Atalay, Ali̇ekber Yapar, Ahmet Yi̇ği̇t Kaptan, İzzet Bi̇ngöl, Mehmet Doğan, Mehmet Fati̇h Ekşi̇oğlu
Turkish Journal of Medical Sciences
Background/aim: Extraskeletal myxoid chondrosarcoma (EMC) is a rare soft tissue sarcoma. The aim of this study is to present the results of the patients we treated with the diagnosis of EMC as an oncology reference center. Materials and methods: Information on 13 patients diagnosed with EMC between 2006 and 2018 was retrospectively reviewed. Patients' demographic information, tumor sizes, surgical treatments, chemotherapy and radiotherapy statuses, follow-up times, recurrences, and metastases were recorded. Results: Mean patient age was 53.6 ± 15 years (range: 28-73). In 8 patients, the tumor was located in the lower limbs, most commonly in the thigh (46.2%). Mean …
Is Microwave Ablation Therapy As Effective As Colorectal Liver Metastases In Noncolorectal Liver Metastases?, Gürkan Danişan, Ali̇ Küpeli̇, Ogün Taydaş
Is Microwave Ablation Therapy As Effective As Colorectal Liver Metastases In Noncolorectal Liver Metastases?, Gürkan Danişan, Ali̇ Küpeli̇, Ogün Taydaş
Turkish Journal of Medical Sciences
Background/aim: The aim of the study was to evaluate the relationship between primary tumor type and the effectiveness of microwave ablation (MWA) therapy by comparing the technical and clinical outcomes of MWA in the treatment of colorectal liver metastases (CLM) and noncolorectal liver metastases (NCLM). Materials and methods: Between January 2019 and March 2021, 47 consecutive patients (25 male, 22 female) with a total of 63 unresectable hepatic metastases underwent MWA under ultrasound guidance. The patients were divided into CLM (n = 29) and NCLM (n = 18) groups. Patient demographics, procedural details, and complications were noted. The overall survival …
Circular Rna Circprmt5 Is Upregulated In Breast Cancer And Is Required For Cellproliferation And Migration, Xiaofeng Li, Dairong Zhang, Zuxi Feng, Xiangjing Xu, Jihong Zhang, Aiping Yu, Li Zhu, Jie Xiao, Junhua Du, Min Chen
Circular Rna Circprmt5 Is Upregulated In Breast Cancer And Is Required For Cellproliferation And Migration, Xiaofeng Li, Dairong Zhang, Zuxi Feng, Xiangjing Xu, Jihong Zhang, Aiping Yu, Li Zhu, Jie Xiao, Junhua Du, Min Chen
Turkish Journal of Medical Sciences
Background/aim: To evaluate the role of cyclic protein arginine methyltransferase 5 (circPRMT5) in the occurrence and development of breast cancer (BC). Materials and methods: A total of 90 BC patients who underwent radical mastectomy and 40 age-matched healthy female controls were recruited in the Second People's Hospital of China Three Gorges University, Yichang Second People's Hospital from 2017 to 2020. Quantitative reverse transcription polymerase chain reaction (RT-qPCR) was used to detect the expression levels of circPRMT5 in BC tissues, serum, normal breast cell line (MCF-10A), and BC cell line (T47D, MCF-7, BT549, Hs-578T, and MDA-MB-231, MDAMB-468). The associations between circPRMT5 …
Does Transrectal Ultrasonography-Guided Biopsy Of The Prostate Lead To Possible Further Metastasis Via Circulating Tumor Cells?, Mustafa Kemal Ati̇lla, Bahatti̇n Avci, Lokman İrkilata, Mustafa Aydin, Alper Bi̇tki̇n, Mevlüt Keleş, İnci̇ Yücel, Mahmut Ulubay
Does Transrectal Ultrasonography-Guided Biopsy Of The Prostate Lead To Possible Further Metastasis Via Circulating Tumor Cells?, Mustafa Kemal Ati̇lla, Bahatti̇n Avci, Lokman İrkilata, Mustafa Aydin, Alper Bi̇tki̇n, Mevlüt Keleş, İnci̇ Yücel, Mahmut Ulubay
Turkish Journal of Medical Sciences
Background/aim: We evaluate whether transrectal ultrasonography (TRUS)-guided prostate biopsy might lead to spillage of tumor cells into peripheral blood as a result of disruption of the epithelial barrier and ultimately result in metastasis. Materials and methods: Eighty-eight patients underwent TRUS-guided prostate needle biopsy due to prostate-specific antigen (PSA) increase or abnormal digital rectal examination at the Samsun Research and Training Hospital (Samsun, Turkey) between April 2016 and September 2018. Approximately 10 mL of whole blood was collected from patients before, 1 week after, and 1 month after biopsy. Samples were analyzed for CD117 positivity and prostate-specific membrane antigen (PSMA) levels …
Abdominal Ultrasonographic Findings In Dogs With Mammary Tumors: Association With Tumor Characteristics And Survival, Daniella Matos Da Silva, Angélica Inajá Juliani, Camila Lopes Ribeiro, Jair Rodini Engracia Filho, Simone Domit Guérios, Tilde Rodrigues Froes
Abdominal Ultrasonographic Findings In Dogs With Mammary Tumors: Association With Tumor Characteristics And Survival, Daniella Matos Da Silva, Angélica Inajá Juliani, Camila Lopes Ribeiro, Jair Rodini Engracia Filho, Simone Domit Guérios, Tilde Rodrigues Froes
Turkish Journal of Veterinary & Animal Sciences
Abdominal ultrasound is frequently performed as part of initial staging of canine mammary tumors. The aims of this study were to describe abdominal ultrasonographic findings present at diagnosis of mammary tumors in dogs and to assess their value for associations with histopathological results and treatment outcome. The medical records of 201 female dogs diagnosed with mammary tumors that had abdominal ultrasonography performed as part of their initial clinical evaluation were reviewed. Histopathological diagnosis of malignant mammary tumors was obtained in most cases (86%; 172 cases). One hundred and fifty-seven animals (78%) had some ultrasonographic abnormality. A total of 338 ultrasonographic …
The Utility Of Ebus-Tbna In Mediastinal Or Hilar Lymph Node Evaluation In Extrapulmonary Malignancy, Onur Fevzi̇ Erer, Ceyda Anar, Serhat Erol, Seri̇r Özkan
The Utility Of Ebus-Tbna In Mediastinal Or Hilar Lymph Node Evaluation In Extrapulmonary Malignancy, Onur Fevzi̇ Erer, Ceyda Anar, Serhat Erol, Seri̇r Özkan
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to determine the diagnostic performance of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in the diagnosis of mediastinal and hilar lymph nodes (LNs) in patients with known extrapulmonary malignancy. Materials and methods: Between March 2011 and August 2013, 378 EBUS-TBNA procedures were performed. Sixty-three (16.6%) of these were performed on known extrapulmonary malignancy patients. Results: There were 28 male and 35 female patients, with median ages of 65 years (min-max: 53-87) and 57 years (min-max: 39-76), respectively. From the 63 cases, 138 lymph nodes (LNs) were sampled with EBUS-TBNA (median: 2 LNs/patient; min-max: 1-4). …
Prognostic Impact Of Matrix Metalloproteinases (Mmp-9 And Mmp-2) And Vascular Endothelial Growth Factor Expression In Non-Small Cell Lung Cancer, Ahmet Yurdakul, Nalan Akyürek, Şenay Yilmaz, Jale Karakaya, Leyla Memi̇ş, Can Öztürk
Prognostic Impact Of Matrix Metalloproteinases (Mmp-9 And Mmp-2) And Vascular Endothelial Growth Factor Expression In Non-Small Cell Lung Cancer, Ahmet Yurdakul, Nalan Akyürek, Şenay Yilmaz, Jale Karakaya, Leyla Memi̇ş, Can Öztürk
Turkish Journal of Medical Sciences
To investigate the role of matrix metalloproteinases (MMPs), MMP-9 and MMP-2, and vascular endothelial growth factor (VEGF) in metastasis and their relationship with survival. Early metastasis is the most common cause of lung cancer death. Angiogenesis and basement membrane damage are necessary for growth and invasion of the tumoral cells. VEGF, involved in angiogenic activity, and MMPs, involved in matrix destruction, are important for metastasis in lung cancer. Materials and methods: Using immunohistochemistry analysis, we evaluated MMP-9, MMP-2, and VEGF expressions in paraffin specimens from 91 patients with histopathologically confirmed non-small cell lung cancer and the relationship between MMP-9, MMP-2, …
The Relationship Of Serum Cea And Ca 19-9 Levels To Liver Metastasis And Pancreatic Invasion In Esophageal Cancer, Ati̇la Türkyilmaz, Ati̇lla Eroğlu, Yener Aydin, Nuretti̇n Karaoğlanoğlu
The Relationship Of Serum Cea And Ca 19-9 Levels To Liver Metastasis And Pancreatic Invasion In Esophageal Cancer, Ati̇la Türkyilmaz, Ati̇lla Eroğlu, Yener Aydin, Nuretti̇n Karaoğlanoğlu
Turkish Journal of Medical Sciences
Aim: Previous studies have examined levels of CEA and CA 19-9 in esophageal cancer patients, but have not determined a significant relationship between CEA and CA 19-9 levels and liver metastasis and pancreatic invasion in patients with esophageal cancer. In this study, we compared the serum levels of CEA and CA 19-9 in patients with esophageal cancer with and without liver and pancreatic metastasis. Materials and methods: The serum levels of CEA and CA 19-9 were measured in clinic patients between January 2007 and January 2008, including 10 patients with liver metastasis (4) and pancreas invasion (6), and 40 patients …
Survival In Esophageal Cancer Patients With Hematogenous Distant Organ Metastases, Ati̇la Türkyilmaz, Ati̇lla Eroğlu, Yener Aydin, Ömer Yilmaz, Nuretti̇n Karaoğlanoğlu
Survival In Esophageal Cancer Patients With Hematogenous Distant Organ Metastases, Ati̇la Türkyilmaz, Ati̇lla Eroğlu, Yener Aydin, Ömer Yilmaz, Nuretti̇n Karaoğlanoğlu
Turkish Journal of Medical Sciences
Objective: Esophageal cancer is a rapidly progressive cancer. In the majority of patients local invasion or distant metastasis may be present at the time of diagnosis. The present study reviewed the records of esophageal cancer patients with hematogenous distant organ metastases with the aim of reporting primary tumor location, histological type, location of metastases, and survival rates, according to treatment administered. Method: Distant organ metastasis was detected in 50 of 316 consecutive patients that presented to the Thoracic Surgery Department of Atatürk University between 2002 and 2007. Patient age and gender, tumor location, history of esophagectomy, metastasis organ, treatment type, …
General Anesthesia For Cesarean Delivery Followed By Anterior And Posterior Spinal Cord Decompression Of A Parturient With Symptomatic Spinemetastasis Due To Breast Cancer, Berri̇n Günaydin, Sema Öncül, Mehmet Erdem, Memduh Kaymaz, Hakan Emmez, Zerri̇n Özköse
General Anesthesia For Cesarean Delivery Followed By Anterior And Posterior Spinal Cord Decompression Of A Parturient With Symptomatic Spinemetastasis Due To Breast Cancer, Berri̇n Günaydin, Sema Öncül, Mehmet Erdem, Memduh Kaymaz, Hakan Emmez, Zerri̇n Özköse
Turkish Journal of Medical Sciences
Cesarean delivery of a parturient suffering from paraplegia followed by anterior corpectomy and posterior spinal cord decompression because of spine metastasis at T1 due to breast cancer was presented. General anesthesia was uneventfully completed after rapid sequence anesthesia induction with propofol, ketamine, and succinylcholine, which was maintained by isoflurane inhalation in 50% oxygen-air mixture until delivery of the newborn. After delivery, remifentanil infusion was added to isoflurane inhalation in approximately 33%/66% oxygen:air until skin closure of the latter operation. Consequently, satisfactory recovery of paraplegia resulting from spine metastasis and delivery of a healthy baby were provided by successful and uneventful …
Uterine And Ovarian Metastasis Of Transmissible Venereal Tumor In A Bitch, Ayhan Baştan, Duygu Baki̇ Acar, Mehmet Cengi̇z
Uterine And Ovarian Metastasis Of Transmissible Venereal Tumor In A Bitch, Ayhan Baştan, Duygu Baki̇ Acar, Mehmet Cengi̇z
Turkish Journal of Veterinary & Animal Sciences
In this case report, metastasis of a transmissible venereal tumor (TVT) to the uterus and ovaries is presented. A 7-year-old female boxer dog with hemorrhagic vulvar discharge and a vaginal mass was brought to Ankara University Faculty of Veterinary Medicine, Clinics of Gynecology and Obstetrics. TVT was diagnosed by clinical findings and cytologic examination. Multifocal nodules in the uterus and enlargements of the uterine wall were detected by ultrasonographic examination. Ovariohysterectomy was performed because of uterine pathology. Histopathologic examination of the uterus and ovarium showed that the multifocal masses in the uterus and ovaries originated from vaginal TVT.