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Full-Text Articles in Medicine and Health Sciences
Influence Of Lactobacillus Plantarum Administration On Some Serum/Tissue (Uterus) Antioxidant And Cytokine Levels In Female Rats Exposed To Cadmium (Cd), İhsan Kisadere, Bariş Güner, Hakan Tavşanli, Mehmet Faruk Aydin, Mustafa Usta
Influence Of Lactobacillus Plantarum Administration On Some Serum/Tissue (Uterus) Antioxidant And Cytokine Levels In Female Rats Exposed To Cadmium (Cd), İhsan Kisadere, Bariş Güner, Hakan Tavşanli, Mehmet Faruk Aydin, Mustafa Usta
Turkish Journal of Veterinary & Animal Sciences
The study aimed to investigate the effects of oral Lactobacillus plantarum (Lp) administration on some serum/tissue (uterus) antioxidant and cytokine levels as well as histopathologic changes in female rats exposed chronically to Cd. For this purpose, rats were separated into four groups including control (C, n = 8), cadmium (Cd, n = 8), Lp (n = 8), and Cd + Lp (n = 8). Cd (dissolved in water at a dose of 2.04 mg/mL) was orally administered to Cd and Cd + Lp groups for 28 days. Besides, active-live Lp, which was grown at a level of approximately 10$^{8}$-10$^{9}$ cfu/mL …
Analysis Of Some Heavy Metals (Cd And Pb) In The Şanlıurfa Province Using Feral Pigeonblood Samples, Özlem Ütme, Füsun Temamoğullari
Analysis Of Some Heavy Metals (Cd And Pb) In The Şanlıurfa Province Using Feral Pigeonblood Samples, Özlem Ütme, Füsun Temamoğullari
Turkish Journal of Veterinary & Animal Sciences
Birds serve as good biomonitors in determining environmental pollution. As for indicators of environmental pollution, we detected blood heavy metal levels in 32 female and 32 male local Feral pigeons in the central districts of Şanlıurfa, located in southeastern Turkey, in one month of each season. The samples were analyzed by coupled plasma-mass spectrometry. Lead (Pb) levels were measured as 233.1 ± 25.7 μg/kg for Haliliye, 101.2 ± 29.7 μg/kg for Karaköprü, 81.3 ± 22.7 μg/kg for Eyyübiye, and 48.1 ± 27.1 μg/ kg for Suruç, whereas cadmium (Cd) levels were measured as 30.6 ± 12.6 μg/kg for Haliliye, 35.7 …
Effects Of Selenium And Zinc Supplementation On Cadmium Toxicity In Broilers, Evangelos Zoidis, Athanasios C. Pappas, Ali Al-Waeli, Constantinos A. Georgiou, George P. Danezis, Nikos Demiris, George Zervas, Konstantinos Fegeros
Effects Of Selenium And Zinc Supplementation On Cadmium Toxicity In Broilers, Evangelos Zoidis, Athanasios C. Pappas, Ali Al-Waeli, Constantinos A. Georgiou, George P. Danezis, Nikos Demiris, George Zervas, Konstantinos Fegeros
Turkish Journal of Veterinary & Animal Sciences
Cadmium (Cd) is a toxic metal regarded as an environmental pollutant. The potential ameliorative effect of simultaneous addition of Se and Zn to broilers against Cd toxicity was examined. A total of 180 as-hatched broilers were used. There were 4 replicate pens of 3 dietary treatments: T1, T2, and T3. In T1, Se, Cd, and Zn were added to a basal diet at 0.3, 0, and 100 ppm, in T2 at 0.3, 50, and 150 ppm, and in T3 at 0.5, 50, and 150 ppm respectively. Selenium, Cd, Ca, Co, Cu, Fe, Li, Mg, Mn, Sb, As, Cr, Pb, Mo, …
Cadmium Affects The Development Of Somites In Chick Embryos(Gallus Gallus Domesticus) Under In Vitro Conditions, Samira Kazemi, Naser Mahdavi Shahri, Roya Lari, Fatemeh Behnam Rassouli
Cadmium Affects The Development Of Somites In Chick Embryos(Gallus Gallus Domesticus) Under In Vitro Conditions, Samira Kazemi, Naser Mahdavi Shahri, Roya Lari, Fatemeh Behnam Rassouli
Turkish Journal of Veterinary & Animal Sciences
Cadmium is one of the most toxic metals that has high environmental stability and can hardly be converted into substances of low toxicity. In the present study, the effects of cadmium on the development of somites of chick embryos under in vitro conditions were investigated. First, fertilized eggs were incubated until they reached the stage of 15?20 somites. The embryos were then separated from the yolk by using the window technique. The somites were separated by insulin needles under a stereomicroscope. The separated somites were then transferred to Dulbecco?s modified Eagle?s medium (DMEM) stock culture and treated with different concentrations …
Effect Of Single Dose Cadmium Chloride Administration On Oxidative Stress In Male And Female Rats, Haki̇ Kara, Fi̇kret Karataş, Hali̇t Canatan
Effect Of Single Dose Cadmium Chloride Administration On Oxidative Stress In Male And Female Rats, Haki̇ Kara, Fi̇kret Karataş, Hali̇t Canatan
Turkish Journal of Veterinary & Animal Sciences
This study was carried out to determine the effect of single dose cadmium chloride (CdCl_2) administration on the possible development of oxidative stress by measuring malondialdehyde (MDA) levels in the liver, kidney and blood serum of male and female rats. For this purpose 80 animals (14-16 weeks old) were initially divided into two 2 groups according to sex, each containing 40 rats. Then both were divided into 5 equal treatment groups [0 (control) 0.5, 1, 2 and 4 mg/kg CdCl_2 body weight by subcutanous injection, respectively]. The blood serum and tissues of the liver and kidney were collected after 24 …
The Effects Of Cadmium On Levels Of Glucose In Serum And Glycogen Reserves In The Liver And Muscle Tissues Of Cyprinus Carpio (L., 1758), Bedi̇i̇ Ci̇ci̇k, Kenan Engi̇n
The Effects Of Cadmium On Levels Of Glucose In Serum And Glycogen Reserves In The Liver And Muscle Tissues Of Cyprinus Carpio (L., 1758), Bedi̇i̇ Ci̇ci̇k, Kenan Engi̇n
Turkish Journal of Veterinary & Animal Sciences
The common carp (Cyprinus carpio L., 1758) was exposed to sublethal concentrations of cadmium (0.05, 0.1, 0.5 and 1.0 mgl^{-1}) for 10 days. The levels of serum glucose and glycogen reserves in the liver and muscle tissues were measured both in fish exposed and not exposed to Cd. The levels of glycogen reserves in the liver and muscle tissues were significantly (P < 0.05) decreased in fish exposed to sublethal concentrations of Cd compared with the levels measured in the control groups. The decrease in glycogen levels in the liver and muscle tissues under the highest metal concentration (1.0 mgl^{-1}) were 24% and 29%, respectively. The blood serum glucose levels of fish exposed to Cd were significantly (P < 0.05) increased compared with the levels measured in the control groups. This increase was correlated with the increase in water Cd concentrations.
Effects Of Heavy Metal Accumulation On The 96-H Lc_50 Values In Tench Tinca Tinca L., 1758, Syed Lal Shah, Ahmet Altindağ
Effects Of Heavy Metal Accumulation On The 96-H Lc_50 Values In Tench Tinca Tinca L., 1758, Syed Lal Shah, Ahmet Altindağ
Turkish Journal of Veterinary & Animal Sciences
The effects of already accumulated heavy metals (Hg, Cd, Pb) in the body of tench on the 96-h LC_50 values of the respective heavy metals were studied. The body concentration of mercury, cadmium and lead was 0.011, 0.32 and 1.59 mg/g respectively, and their 96-h LC_50 values were 1.0, 6.5 and 300.0, ppm, respectively. The general accumulation order of heavy metals and their respective 96-h LC_50 values were Hg< Cd< Pb. It was observed that the fish with lowest body concentration of heavy metal showed the lowest 96-h LC_50 value of the respective heavy metal and vice versa. This close relationship showed that the previous body accumulation of heavy metals has a direct effect on the 96-h LC_50 values of the respective heavy metals and the susceptibility of fish.
Alterations In The Immunological Parameters Of Tench (Tinca Tinca L. 1758) After Acute And Chronic Exposure To Lethal And Sublethal Treatments With Mercury, Cadmium And Lead, Syed Lal Shah, Ahmet Altindağ
Alterations In The Immunological Parameters Of Tench (Tinca Tinca L. 1758) After Acute And Chronic Exposure To Lethal And Sublethal Treatments With Mercury, Cadmium And Lead, Syed Lal Shah, Ahmet Altindağ
Turkish Journal of Veterinary & Animal Sciences
Tinca tinca were exposed to lethal and sublethal treatments with mercury, cadmium and lead for acute and chronic periods to study alterations in immunological parameters. Acute lethal exposure (Lc_{50}/48 h ; 96-h Lc_{50} of Hg 1.0, Cd 6.5, Pb 300 ppm) caused a significant increase in Lct in the Hg treatment and a significant decrease in the Pb treatment, and a significant decrease in total WBC count in the Hg and Cd treatments. Lower acute sublethal exposures (10% Lc50/24 h), caused a significant increase in Lct in the Hg and Pb, treatments and a significant increase in total WBC count …
Effects Of Cadmium On Uterine Contractions In Different Species In Vitro, Haki̇ Kara, Kadi̇r Servi̇, Yaşar Akar
Effects Of Cadmium On Uterine Contractions In Different Species In Vitro, Haki̇ Kara, Kadi̇r Servi̇, Yaşar Akar
Turkish Journal of Veterinary & Animal Sciences
The aim of this study was to examine the effects of cadmium on oxytocin-induced myometrium contractions in rats, cows and cats in vitro. The frequency was 12.20 ± 1.2, 11.25 ± 2.7 and 10.70 ± 2.5/10 min, respectively, after 0.01 mM oxytocin induced with myometrial samples in rats, cows and cats. The peak amplitude was 3.84 ± 0.50, 3.44 ± 0.65 and 3.35 ± 0.45 g, respectively, after oxytocin induction. The frequency and peak amplitude decreased after the addition of 0.01 mM cadmium chloride (CdCl_2). The frequency was 1.2 ± 0.4 (p < 0.001), 2.5 ± 0.5 (p < 0.001) and 2.0 ± 0.6(p < 0.001), respectively, and the peak amplitude was 0.7 ± 0.3 (p < 0.001), 1.2 ± 0.2 (p < 0.001) and 0.8 ± 0.4 g (p < 0.001), respectively, in rat, cow and cat myometrium. Finally, the myometrium contractions were completely inhibited in the three species. In conclusion, the effects of cadmium may inhibit both calcium channels and the intracellular-induced mechanism.
Effects Of Different Concentrations Of Copper Alone And A Copper + Cadmium Mixture On The Accumulation Of Copper In The Gill, Liver, Kidney And Muscle Tissues Of Oreochromis Niloticus (L.), Baybars Sağlamti̇mur, Bedi̇i̇ Ci̇ci̇k, Cahi̇t Erdem
Effects Of Different Concentrations Of Copper Alone And A Copper + Cadmium Mixture On The Accumulation Of Copper In The Gill, Liver, Kidney And Muscle Tissues Of Oreochromis Niloticus (L.), Baybars Sağlamti̇mur, Bedi̇i̇ Ci̇ci̇k, Cahi̇t Erdem
Turkish Journal of Veterinary & Animal Sciences
Experiments were conducted in two series for 1, 7, 15 and 30 days. In the first series, fish were exposed to 0.1, 0.5, 1.0 and 5.0 ppm of copper and in the second series to 0.1 + 0.05, 0.5 + 0.1, 1.0 + 0.5 and 5.0 + 1.0 ppm of copper and cadmium mixtures. No mortalities were observed during the experimental period. Accumulation of copper in the tissues and organs increased with increasing concentrations of copper and with longer exposure periods. Copper accumulation associated with copper + cadmium mixtures in the gill, liver, kidney and muscle tissues varied with the …
Effect Of Cadmium Accumulation On Total Protein Levels In Tilapia Nilotica, Mustafa Kalay, Cahi̇t Erdem
Effect Of Cadmium Accumulation On Total Protein Levels In Tilapia Nilotica, Mustafa Kalay, Cahi̇t Erdem
Turkish Journal of Veterinary & Animal Sciences
The aim of the present study was to determine the accumulation of cadmium in different tissues of Tilapia nilotica and to establish the influence of this accumulation on total protein levels in liver and kidney tissues. At the end of each experimental period; gill, liver and kidney tissues from the animals were dissected and their cadmium accumulation was determined using atomic absorbtion spectrophotometry. Liver and kidney tissues were homogenised to determine total protein levels. The protein contents of the tissue homogenates were determined by the Lowry method. Cadmium accumulation was higher in the gill, liver and kidney tissues. Cadmium primarily …
The Effect Of Long-Term Supplemental Dietary Cadmium On Lipid Peroxidation And The Antioxidant System In The Liver And Kidneys Of Rabbits, Ebru Beytut, Mesut Aksakal
The Effect Of Long-Term Supplemental Dietary Cadmium On Lipid Peroxidation And The Antioxidant System In The Liver And Kidneys Of Rabbits, Ebru Beytut, Mesut Aksakal
Turkish Journal of Veterinary & Animal Sciences
We investigated the effects of chronic exposure to dietary cadmium (Cd) on the levels of lipid peroxidation (LPO) and reduced glutathione (GSH) associated with activities of glutathione peroxidase (GSH-Px) and the catalase (CAT) enzyme in the liver and kidneys of rabbits. Twenty 10-month-old clinically healthy New Zealand white rabbits (10/group) of 3545 ± 250 g average body weight were used. The control group was allowed to take food and tap water ad libitum, while the experimental group was given tap water containing 200 ppm CdCl_2/L for 28 weeks. Lipid peroxidation contents increased significantly in the liver (p < 0.001) and kidneys (p < 0.005) of Cd-treated rabbits. Glutathione levels decreased significantly in both the liver (p < 0.001) and the kidneys (p < 0.005) of the experimental group. Cadmium treatment caused a significant decrease in the activities of GSH-Px and CAT in the liver (p < 0.001, p < 0.01) and kidneys (p < 0.005, p < 0.1) of the rabbits. These results indicated that a Cd-induced increase in LPO was associated with reductions in GSH-Px and CAT enzyme activities, and in GSH levels in the liver and kidneys of rabbits.
In Vivo Interaction Between Cadmium And Essential Trace Elements Copper And Zinc In Rats, H. Hakan Aydin, Canan Çoker, Bi̇ltan Ersöz
In Vivo Interaction Between Cadmium And Essential Trace Elements Copper And Zinc In Rats, H. Hakan Aydin, Canan Çoker, Bi̇ltan Ersöz
Turkish Journal of Medical Sciences
The complex in vivo interaction between Cd, a toxic metal and essential trace elements, mainly Zn and Cu, has not been elucidated yet. The objective being the elucidation of this interrelationship, Cd was subcutaneously administered as CdCI_2 (1 mg/kg/day) for 5 consecutive days to Swiss albino male rats (n=10). After 5 days, the rats were decapitated. Cd, Zn and Cu levels were estimated in hepatic, renal, cardiac and skeletal muscle specimens. Cd was found to be significantly elevated in all tissues (p< 0.001). Zn was increased in hepatic and renal tissues (p< 0.001 and p< 0.05) compared to the controls. Cu was also significantly increased in these tissues. Myocardial and skeletal muscle tissues also manifested a significant increase in Cu and Zn in this group. It is concluded that Cd administration alters the Zn and Cu status in vivo. However, the mechanism underlying the interactions between toxic and essential elements should be further investigated.