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Full-Text Articles in Medicine and Health Sciences

Effect Of Carotid Stenosis On The Development Of Subarachnoid Hemorrhage: An Experimental Study, Canan Atalay, Ednan Bayram, Mehmet Dumlu Aydin, Mehmet Bi̇li̇ci̇, Zafer Okumuş, Cemal Gündoğdu Jan 2005

Effect Of Carotid Stenosis On The Development Of Subarachnoid Hemorrhage: An Experimental Study, Canan Atalay, Ednan Bayram, Mehmet Dumlu Aydin, Mehmet Bi̇li̇ci̇, Zafer Okumuş, Cemal Gündoğdu

Turkish Journal of Medical Sciences

Subarachnoid hemorrhage (SAH) may be seen after the invasive procedures of occlusive carotid artery disease. The objective of this experimental study is to investigate the effect of bilateral common carotid artery ligation (BCCAL) on the development of subarachnoid hemorrhage (SAH).Twenty Wistar adult rats (150-200g) were randomly divided into two groups, as follows: (ı) Control group (without BCCAL, n = 5), (II) BCCAL group (n = 15). All rats were sacrificed three months later. The basilar artery with surrounding tissue was removed from the cranium and processed for paraffin embedding. Histopathological and Stereological examinations of the basilar artery were made. During …


The Effects Of Qualitative And Quantitative Protein Malnutrition On Cecal Microbiota In Wistar Rats With Or Without Neutrophil Suppression, Hali̇l Biyik, Muharrem Balkaya, Hümeyra Ünsal, Cengi̇z Ünsal Jan 2005

The Effects Of Qualitative And Quantitative Protein Malnutrition On Cecal Microbiota In Wistar Rats With Or Without Neutrophil Suppression, Hali̇l Biyik, Muharrem Balkaya, Hümeyra Ünsal, Cengi̇z Ünsal

Turkish Journal of Veterinary & Animal Sciences

Gastrointestinal microbiota has been claimed to be affected by the diet consumed. In this study the effects of severe qualitative and quantitative protein malnutrition on cecal microbiota of male Wistar rats with or without neutrophil depletion were investigated. A total of 43 animals were divided randomly into 7 groups. Group I (control) was given a complete chow diet, groups II, III and IV received almost protein free (N-free) diet and groups V, VI and VII received a 20% gelatin containing diet for 35 days ad libitum. In addition, groups I, II and V were given physiologic saline, groups III and …


The Effects Of Fenfluramine On Blood And Tissue Serotonin (5-Hydroxytryptamine) Levels In Rats, İbrahi̇m Pi̇ri̇nçci̇, Ahmet Ateşşahi̇n, İzzet Karahan Jan 2005

The Effects Of Fenfluramine On Blood And Tissue Serotonin (5-Hydroxytryptamine) Levels In Rats, İbrahi̇m Pi̇ri̇nçci̇, Ahmet Ateşşahi̇n, İzzet Karahan

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to investigate the effect of fenfluramine (FEN) administered at single and repeated doses on brain, stomach and plasma serotonin (5-Hydroxytryptamine, 5-HT) levels in rats. FEN was injected intraperitoneally at single doses (1, 3 and 10 µmol kg^{-1}) and given orally at repeated doses (1.25, 5 and 10 mg kg^{-1}) for 21 days. The tissues and plasma samples were collected 20, 40, 80 and 160 minutes after the single dose administrations and 4 h after the last dose administration in repeated experiments. In addition, the rats treated with the dose of 1.25 mg kg^-1 were …