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Articles 31 - 60 of 62
Full-Text Articles in Medicine and Health Sciences
Stroke In Brazil: A Neglected Disease, Paulo A. Lotufo
Stroke In Brazil: A Neglected Disease, Paulo A. Lotufo
Paulo A Lotufo
The turning point in the transition from infectious diseases to non-transmittable diseases in Brazil occurred in the 1960s, taking the country as a whole. However, considering the main cities, such as São Paulo and Rio de Janeiro, cerebrovascular disease mortality rates have surpassed the “old cardiovascular diseases” like rheumatic heart disease and syphilitic aortic disease since the end of World War II. Until the end of the 1980s, the burden of stroke mortality observed in the main Brazilian cities was higher than in the United States, Canada and western European countries, and similar to what is observed in Eastern Europe …
Trends Of Stroke Subtypes Mortality In Sao Paulo, Brazil (1996-2003), Paulo A. Lotufo, Isabela M. Bensenor
Trends Of Stroke Subtypes Mortality In Sao Paulo, Brazil (1996-2003), Paulo A. Lotufo, Isabela M. Bensenor
Paulo A Lotufo
The decline of stroke mortality rates has been described in Brazil; however, there is no data about stroke subtypes. We described the changes of stroke mortality rates in the city of Sao Paulo (1996-2003) emphasizing intracerebral hemorrhage and cerebral infarction. We categorized mortality data by gender and 10-year age-strata from 30 to 79 years-old. For men, an annual reduction of all types of stroke (-3.9%), and of stroke subtypes as intracerebral hemorrhage (-3.0%) and cerebral infarction was observ e d (-2.7%) as well as, a decline of ill-defined stroke (-7.4%). For women, a decline was observed for all types of …
Why Brazil Does Not Have An Epidemic Of Chronic Diseases: Some Answers From Cardiovascular Diseases, Paulo A. Lotufo
Why Brazil Does Not Have An Epidemic Of Chronic Diseases: Some Answers From Cardiovascular Diseases, Paulo A. Lotufo
Paulo A Lotufo
No abstract provided.
The "Common Soil" Theory: Coronary Disease, Diabetes And Inflammation., Paulo A. Lotufo
The "Common Soil" Theory: Coronary Disease, Diabetes And Inflammation., Paulo A. Lotufo
Paulo A Lotufo
No abstract provided.
Progress Testing: Evaluation Of Four Years Of Application In The School Of Medicine, University Of São Paulo, Paulo A. Lotufo
Progress Testing: Evaluation Of Four Years Of Application In The School Of Medicine, University Of São Paulo, Paulo A. Lotufo
Paulo A Lotufo
Progress testing is a longitudinal tool for evaluating knowledge gains during the medical school years. Objectives: (1) To implement progress testing as a form of routine evaluation; (2) to verify whether cognitive gain is a continuous variable or not; and (3) to evaluate whether there is loss of knowledge relating to basic sciences in the final years of medical school. Methods: A progress test was applied twice a year to all students from 2001 to 2004. The mean percentage score was calculated for each school year, employing ANOVA with post hoc Bonferroni test evaluation for each test. Results:Progress testing was …
Establishment And Characterization Of An Oral Squamous Carcinoma Cell Line From A Patient With No Apparent Habits Associated With Oral Cancer, Sok C. C., Hamid S., Peng L. K., Ismail S. M., Rosnah Binti Zain
Establishment And Characterization Of An Oral Squamous Carcinoma Cell Line From A Patient With No Apparent Habits Associated With Oral Cancer, Sok C. C., Hamid S., Peng L. K., Ismail S. M., Rosnah Binti Zain
Prof. Dr. Rosnah Binti Zain
Introduction: We have established a cell line ORL-48(T) from a surgically resected specimen of an untreated primary human oral squamous cell carcinona of the mandible.This patient did not appear to have any oral habits which have been reported to be associated with oral cancer Materials and Method: The in vitro growth characteristics, epithelial origin, in vitro anchorage independency, HPV infection, microsatellite instability status, karyotype and the status of various cell cycle regulators and gatekeepers of the ORL-48(T) cell line were investigated. Results: The ORL-48(T) cell line is immortal, 3T3- independent and grew as a monolayer with the doubling time of …
Darier Disease: A Case Report, Jalil A. A., Rosnah Binti Zain, Van Der Waal, I.
Darier Disease: A Case Report, Jalil A. A., Rosnah Binti Zain, Van Der Waal, I.
Prof. Dr. Rosnah Binti Zain
Darier disease, also known as keratosis follicularis, dyskeratosis follicularis, and benign dyskeratosis, is a rare disorder of keratinisation that primarily affects the skin and, to a lesser extent, the oral mucosa. It was described independently by both Darier and White in 1889. It has a prevalence of 1:100,000 of the population and is inherited as an autosomal dominant trait.1 The age of onset is childhood or adolescence. Patients usually present with multiple small firm reddish-brown papules on the forehead, scalp, neck, shoulders, chest, and limbs. Other cutaneous signs include punctate keratotic pits of the palms and soles and dystrophy of …
Facilitating Communication: How To Truly Understand What Patients Mean, Mona Shattell, Beverly Hogan
Facilitating Communication: How To Truly Understand What Patients Mean, Mona Shattell, Beverly Hogan
Mona Shattell
No abstract provided.
You Catch More Flies With Honey: But Patients Shouldn’T Have To Manipulate Nurses To Receive Good Care, Mona Shattell
You Catch More Flies With Honey: But Patients Shouldn’T Have To Manipulate Nurses To Receive Good Care, Mona Shattell
Mona Shattell
No abstract provided.
The Ecology Of Bipolar Disorder: The Importance Of Sleep, Mona Shattell, Mary Umlauf
The Ecology Of Bipolar Disorder: The Importance Of Sleep, Mona Shattell, Mary Umlauf
Mona Shattell
Although much of the emphasis on treating Bipolar Disorder patients is pharmacotherapy, sleep loss is an important trigger for mania and plays an important role in the condition. The purpose of this paper is to fully explore the chronobiological, environmental, social and genetic factors that contribute to the sleep disruption that is characteristic of mania and bipolar disorder. This review is important because sleep, chronobiology and genetics are under-emphasized content areas in nursing education. As a result many practicing nurses are unaware of the importance of sleep for mental health or what to teach patients to improve both the quality …
The Scholarship Of Engagement In Nursing, Mona Shattell, Joseph Burrage, Barbara Haberman
The Scholarship Of Engagement In Nursing, Mona Shattell, Joseph Burrage, Barbara Haberman
Mona Shattell
We propose the time is right for the Scholarship of Engagement to serve as a model of scholarship in schools of nursing given the shift towards community based research and the emphasis of communitybased research in the recently published National Institutes of Health (NIH) roadmap initiative. Thus, this article addresses the need of nursing academe to embrace a broader paradigm of scholarship, the Scholarship of Engagement, in order to expand knowledge development via implementation of the NIH roadmap. The need for implementation of a broader paradigm of nursing science within the context of nursing academics’ roles is discussed.
“It’S The People That Make The Environment Good Or Bad:” The Patient’S Experience Of The Acute Care Hospital Environment, Mona Shattell, Beverly Hogan, Sandra Thomas
“It’S The People That Make The Environment Good Or Bad:” The Patient’S Experience Of The Acute Care Hospital Environment, Mona Shattell, Beverly Hogan, Sandra Thomas
Mona Shattell
A review of contemporary nursing research reveals a tendency to focus on select aspects of the hospital environment such as noise, light, and music. Although studies such as these shed light on discrete aspects of the hospital environment, this body of literature contributes little to an understanding of the entirety of that world as the patient in the sickbed experiences it. The purpose of the study detailed in this article was to describe the patient’s experience of the acute care hospital environment. Nondirective, in-depth phenomenological interviews were conducted, then transcribed verbatim, and analyzed for themes. Against the backdrop of “I …
“Putting Feet To What We Pray About:” The Experience Of Caring By Faith-Based Care Team Members, Mona Shattell, Catherine Hasty
“Putting Feet To What We Pray About:” The Experience Of Caring By Faith-Based Care Team Members, Mona Shattell, Catherine Hasty
Mona Shattell
The purpose of this study was to explore the experience of caring by faith-based care team members. Nondirective, in-depth phenomenological interviews were conducted, transcribed verbatim, and analyzed for themes. Participants included 19 care team members who served on faith-based care teams providing in-home support for families with chronic and/or terminal illness. Analysis of the interview texts resulted in the following four themes: "putting feet to what we pray about," "building and sharing relationships," "it makes you more aware," and "because it's a team." Participants expressed a strong reciprocity in their experience; for example, "it's a mutual thing but I think …
“Nurse Bait:” Strategies Hospitalized Patients Use To Entice Nurses Within The Context Of The Nurse-Patient Relationship, Mona Shattell
“Nurse Bait:” Strategies Hospitalized Patients Use To Entice Nurses Within The Context Of The Nurse-Patient Relationship, Mona Shattell
Mona Shattell
Patients on medical-surgical and psychiatric inpatient units long for more and deeper connections with nurses. Patients’ dependence on the nursing staff, as well as their perceived powerlessness, creates a situation where patients believe they have to actively find ways to seek needed nursing care. This paper will describe active strategies used by medical-surgical patients to entice nurses within the context of the nurse-patient relationship; strategies designed to mitigate vulnerability and increase interpersonal connection. Implications for nursing practice and for Peplau’s Theory of Interpersonal Relations will be presented.
Development And Validation Of The Sport Emotion Questionnaire, Marc V. Jones, Andrew M. Lane, Steven R. Bray, Mark Uphill, James Catlin
Development And Validation Of The Sport Emotion Questionnaire, Marc V. Jones, Andrew M. Lane, Steven R. Bray, Mark Uphill, James Catlin
Marc Jones
The present paper outlines the development of a sport-specific measure of precompetitive emotion to assess anger, anxiety, dejection, excitement, and happiness. Face, content, factorial, and concurrent validity were examined over four stages. Stage 1 had 264 athletes complete an open-ended questionnaire to identify emotions experienced in sport. The item pool was extended through the inclusion of additional items taken from the literature. In Stage 2 a total of 148 athletes verified the item pool while a separate sample of 49 athletes indicated the extent to which items were representative of the emotions anger, anxiety, dejection, excitement, and happiness. Stage 3 …
Coming Of Age And Taking Stock: The State Of Academic Health Policy Research Centres In Canada, Michele L. Mekel, Samuel E.D Shortt
Coming Of Age And Taking Stock: The State Of Academic Health Policy Research Centres In Canada, Michele L. Mekel, Samuel E.D Shortt
Michele L Mekel
This descriptive study takes stock of Canada's health services and health policy research capacity by profiling the organizational models, operational challenges, and success strategies utilized by Canadian academic health policy research centres. While each such centre is unique, the results point to some common themes, including symbiotic relationships between centres and their ministries of health, pervasive infrastructure funding challenges and the importance of having a supportive academic home.
The Effects Of Oxygen-Based Disinfectant On Dimensional Accuracy Of Alginates, Noor Hayaty Abu Kasim Abu Kasim N.H.
The Effects Of Oxygen-Based Disinfectant On Dimensional Accuracy Of Alginates, Noor Hayaty Abu Kasim Abu Kasim N.H.
Noor Hayaty Abu Kasim Abu Kasim N.H.
Objective: This study evaluated the effect of an active oxygen based disinfectant, 2% Perform® (Schulke & Mayr, Germany) on the dimensional accuracy of four alginates, Alginoplast (Heraeus Kulzer, Holland), Kromopan (LASCOD, Italy), Alginmax (MAJOR, Italy) and Duplast (Dentsply, China). Method: A cobalt chromium master model with four cylindrical studs representing 2 canines and 2 molars was constructed. A total of 40 impressions for each alginates were taken and treated in 4 different conditions, Immediate pour (control); 10 minutes immersion in distilled water; 10 minutes immersion in 2% Perform® and 30 minutes in 2% Perform®. The impressions were then poured in …
"Rassling The Hog": The Influence Of Correlated Item Error On Internal Consistency, Classical Reliability, And Congeneric Reliability, Joseph F. Lucke
"Rassling The Hog": The Influence Of Correlated Item Error On Internal Consistency, Classical Reliability, And Congeneric Reliability, Joseph F. Lucke
Joseph Lucke
The properties of internal consistency ($\alpha$), classical reliability ($\rho$), and congeneric reliability ($\omega$) for a composite test with correlated item error were analytically investigated. Possible sources of correlated item error are contextual effects, item bundles, and item models that ignore additional attributes or higher-order attributes. The relation between reliability and internal consistency is determined by the deviance from true-score equivalence. Reliability (classical or congeneric) is internal consistency plus the relative deviance from true-score equivalence. The influence of correlated item error on $\alpha$, $\rho$, and $\omega$ is conveyed strictly through the total item error covariance. As the total item error covariance …
E-Technologies For Public Health Preparedness And Surveillance, Francisco Soto Mas, Joseph Tan
E-Technologies For Public Health Preparedness And Surveillance, Francisco Soto Mas, Joseph Tan
Francisco Soto Mas
No abstract provided.
Health Status And Access To Health Care Of Documented And Undocumented Immigrant Latino Women, Francisco Soto Mas, Khiya J. Marshall
Health Status And Access To Health Care Of Documented And Undocumented Immigrant Latino Women, Francisco Soto Mas, Khiya J. Marshall
Francisco Soto Mas
Immigrant Latino women represent about one fifth of the total Latino population; however, data on health status and access to care for this population is limited. Using secondary data, we used a cross-sectional study to examine sociodemographic, migration, health status, and access to health care characteristics of immigrant documented and undocumented Latino women in North Texas. Undocumented women were less likely to report having health insurance and a regular health care provider, and reported lower education and income. These results support the need forproviding immigrant women with health services such as health fairs, affordable health insurance programs, community health services, …
Detection Of Oncogenic Mutations In The Egfr Gene In Lung Adenocarcinoma With Differential Sensitivity To Egfr Tyrosine Kinase Inhibitors, Torstein Tengs
Detection Of Oncogenic Mutations In The Egfr Gene In Lung Adenocarcinoma With Differential Sensitivity To Egfr Tyrosine Kinase Inhibitors, Torstein Tengs
Dr. Torstein Tengs
The complete sequencing of the human genome and the development of molecularly targeted cancer therapy have promoted efforts to identify systematically the genetic alterations in human cancer. By high-throughput sequencing of tyrosine kinase genes in human non-small-cell lung cancer, we identified somatic mutations in the kinase domain of the epidermal growth factor receptor tyrosine kinase gene (EGFR) that are correlated with clinical response to EGFR tyrosine kinase inhibitors (TKIs). We have shown that these mutant forms of EGFR induce oncogenic transformation in different cellular systems. Cells whose growth depends on EGFR with mutations in exons 19 and 21 are sensitive …
Stress Reduction As A Means To Enhance Oral Immunity In Hiv-Infected Individuals, Kenneth D. Phillips
Stress Reduction As A Means To Enhance Oral Immunity In Hiv-Infected Individuals, Kenneth D. Phillips
Kenneth D. Phillips
No abstract provided.
Sleep Disturbance And Depression As Barriers To Adherence, Kenneth D. Phillips
Sleep Disturbance And Depression As Barriers To Adherence, Kenneth D. Phillips
Kenneth D. Phillips
No abstract provided.
Sleep Quality And Health-Related Quality Of Life In Hiv-Infected African-American Women Of Childbearing Age, Kenneth D. Phillips
Sleep Quality And Health-Related Quality Of Life In Hiv-Infected African-American Women Of Childbearing Age, Kenneth D. Phillips
Kenneth D. Phillips
No abstract provided.
A Peer-Based Substance Abuse Intervention For Hiv+ Rural Women: A Pilot Study, Kenneth D. Phillips
A Peer-Based Substance Abuse Intervention For Hiv+ Rural Women: A Pilot Study, Kenneth D. Phillips
Kenneth D. Phillips
No abstract provided.
Patterns Of Risk Of Depressive Symptoms Among Hiv-Positive Women In The Southeastern United States, Linda Moneyham, Carolyn Murdaugh, Kenneth D. Phillips, Kirby Jackson, Abbas Tavakoli, Mary Boyd, Medha Vyavaharkar
Patterns Of Risk Of Depressive Symptoms Among Hiv-Positive Women In The Southeastern United States, Linda Moneyham, Carolyn Murdaugh, Kenneth D. Phillips, Kirby Jackson, Abbas Tavakoli, Mary Boyd, Medha Vyavaharkar
Kenneth D. Phillips
Depressive symptoms are a common response to HIV disease, and women appear to be at particularly high risk. The authors report results from a crosssectional analysis of data collected from 280 rural women with HIV/AIDS in the Southeastern United States aimed at identifying risk factors of depressive symptoms. Stress theory provided a framework for identification of potential risk factors. Descriptive statistics, measures of association, and regression analyses were used to systematically identify patterns of risk. The final regression model included 22 factors that accounted for 69% of the variance in depressive symptoms. The majority of variance in depressive symptoms was …
Through The Lens Of Merleau-Ponty:Advancing The Phenomenological Approach To Nursing Research, Sandra Thomas
Through The Lens Of Merleau-Ponty:Advancing The Phenomenological Approach To Nursing Research, Sandra Thomas
Sandra Thomas
No abstract provided.
Women's Anger, Agression, And Violence, Sandra Thomas
Women's Anger, Agression, And Violence, Sandra Thomas
Sandra Thomas
Themes of powerlessness, power, and paradox predominate in this reflection on more than 15 years of research on women's anger. Studies conducted in the United States, France, and Turkey are highlighted. These studies have negated several myths while illuminating the general rationality of women's anger: It is squarely grounded in interpersonal interactions in which people deny women power or resources, treat them unjustly, or behave irresponsibly toward them. The offenders are not strangers; rather they are their closest intimates. But few women learned healthy anger expression while growing up. Anger is a confusing and distressing emotion for women, intermingled with …
An Exploration Of Problematic Interviewee Behaviors In Qualitative Research, M. Collins, M. Shattell, Sandra Thomas
An Exploration Of Problematic Interviewee Behaviors In Qualitative Research, M. Collins, M. Shattell, Sandra Thomas
Sandra Thomas
The interview is a staple of many qualitative approaches. Although textbooks offer extensive guidance to researchers about conducting interviews, less guidance is available about problematic interviewee behaviors, such as flattery or statements indicative of social desirability response bias. In this study, a secondary analysis of 22 phenomenological interview transcripts, we sought to examine problematic interviewee behaviors. More than 300 pages of typed text were subjected to line-by-line scrutiny, yielding only six potential instances of the phenomenon. Each could be interpreted several ways. What appeared to be flattery could also be perceived as simple gratitude or appreciation. We concluded that problematic …
Lack Of Antigen-Specific Tissue Remodeling In Mice Deficient In The Macrophage Galactose-Type Calcium-Type Lectin 1/Cd301a., Thandi M. Onami, K. Sato, Y. Imai, N. Higashi, Y. Kumamoto, S. M. Hedrick, T. Irimura
Lack Of Antigen-Specific Tissue Remodeling In Mice Deficient In The Macrophage Galactose-Type Calcium-Type Lectin 1/Cd301a., Thandi M. Onami, K. Sato, Y. Imai, N. Higashi, Y. Kumamoto, S. M. Hedrick, T. Irimura
Thandi M. Onami
Macrophage galactose-type C-type lectins (MGLs), which were recently named CD301, have 2 homologues in mice: MGL1 and MGL2. MGLs are expressed on macrophages and immature dendritic cells. The persistent presence of granulation tissue induced by a protein antigen was observed in wild-type mice but not in mice lacking an endogenous, macrophage-specific, galactose-type calcium-type lectin 1 (MGL1) in an air pouch model. The anti-MGL1 antibody suppressed the granulation tissue formation in wild-type mice. A large number of cells, present only in the pouch of MGL1-deficient mice, were not myeloid or lymphoid lineage cells and the number significantly declined after administration of …