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Articles 421 - 431 of 431

Full-Text Articles in Medicine and Health Sciences

Seizure Threshold In Electroconvulsive Therapy: I. Initial Seizure Threshold, C. Edward Coffey, Joseph Lucke, Richard D. Weiner, Andrew D. Krystal, Michael Aque Jan 1995

Seizure Threshold In Electroconvulsive Therapy: I. Initial Seizure Threshold, C. Edward Coffey, Joseph Lucke, Richard D. Weiner, Andrew D. Krystal, Michael Aque

Joseph Lucke

We measured initial seizure threshold by means of a structured stimulus dosage titration procedure in a clinical sample of 111 depressed patients undergoing brief-pulse, constantcurrent electroconvulsive therapy (ECT). Initial seizure threshold was approximately 60 millicoumbs (mc) (10 Joules) on average, but varied widely (6-fold) across patients. Initial seizure threshold was predicted by four variables: electrode placement (higher with bilateral), gender (higher in men), age (higher with increasing age), and dynamic impedance (inverse relationship). Use of neuroleptic medication was associated with a lower seizure threshold. EEG seizure duration was inversely related to initial seizure threshold, but no other relations with seizure …

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Seizure Threshold In Electroconvulsive Therapy (Ect): Ii. The Anticonvulsant Effect Of Ect, C. Edward Coffey, Joseph Lucke, Richard D. Weiner, Andrew D. Krystal, Michael Aque Jan 1995

Seizure Threshold In Electroconvulsive Therapy (Ect): Ii. The Anticonvulsant Effect Of Ect, C. Edward Coffey, Joseph Lucke, Richard D. Weiner, Andrew D. Krystal, Michael Aque

Joseph Lucke

To measure the anticonvulsant effects of a course of electroconvulsive therapy (ECT), we used a flexible stimulus dosage titration procedure to estimate seizure threshold at the first and sixth ECT treatments in 62 patients with depression who were undergoing a course of brief pulse, constant current ECT given at moderately suprathreshold stimulus intensity. Seizure threshold increased by approximately 47% on average, but only 35 (56%) of the 62 patients showed a rise in seizure threshold. The rise in seizure threshold was associated with increasing age, but not with gender, stimulus electrode placement, or initial seizure threshold. Dynamic impedance decreased by …

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Assessing Sequential Oncogene Amplification In Human Breast Cancer, Laura E. Janocko, Joseph F. Lucke, David W. Groft, Kathryn A. Brown, Charles A. Smith, Agnese A. Pollice, Sarita G. Singh, Robert Yakulis, Robert J. Hartsock, Stanley E. Shackney Jan 1995

Assessing Sequential Oncogene Amplification In Human Breast Cancer, Laura E. Janocko, Joseph F. Lucke, David W. Groft, Kathryn A. Brown, Charles A. Smith, Agnese A. Pollice, Sarita G. Singh, Robert Yakulis, Robert J. Hartsock, Stanley E. Shackney

Joseph Lucke

Studies of amplification and/or overexpression of c-myc, HER-2/neu, and H-ras in breast cancer have shown that each is associated with a poor prognosis. The purpose of this study was to explore the possibility that there is a preferred sequence of amplification of these oncogenes in breast cancer. The frequencies of amplification and patterns of co-amplification of c-myc, HER-2/neu, and H-ras were studied in a group of 84 breast cancers. The data suggested a preferred sequence of amplification that consisted of c-myc amplification-HER-2/neu amplification-H-ras amplification. This model was supported by loglinear analysis. In addition, the levels of amplification of JC-A, a …

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Testing The Null Hypothesis In Small Area Analysis, Kevin Cain, Paula Diehr Jan 1992

Testing The Null Hypothesis In Small Area Analysis, Kevin Cain, Paula Diehr

Paula Diehr

The goal of small area analysis is often to demonstrate that hospital admission rates or procedure rates vary greatly among regions, suggesting the occurrence of unnecessary admissions or procedures in some regions. Recent articles have shown that such variation may be largely due to chance, even if no underlying differences exist among the small areas; thus, it is important to test if the observed variation is larger than expected by chance. In this article we discuss how the appropriate method for testing the null hypothesis depends on the distribution of the number of admissions at the person level. If it …

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The Saurian Psyche Revisted: Lizards In Research, Neil Greenberg Jan 1992

The Saurian Psyche Revisted: Lizards In Research, Neil Greenberg

Neil Greenberg

This essay is intended to guide researchers interested in lizards as prospective experimental models to identify an appropriate species for their research needs and to care for lizards in a manner that will not compromise their utility. Coupled with these is a concern for critical thinking about the ethical dimension of lizard research, one guide for which is to consider the intersection of human needs and lizard needs. Before proceeding further, several arbitrary premises must be made clear: 1. While wholly deserving of study because of their intrinsic interest, I will assume that the lizard research to be undertaken is …

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An Existential-Phenomenological Investigation Of The Psychotherapeutic Interpretive Process Enabling Immediate Insight, Paul Murray Ph.D. Jan 1991

An Existential-Phenomenological Investigation Of The Psychotherapeutic Interpretive Process Enabling Immediate Insight, Paul Murray Ph.D.

Dr. Paul Murray

An Existential-Phenomenological Investigation Of The Psychotherapeutic Interpretive Intervention Process Enabling Immediate Insight: Theoretical and technical preoccupations with the value of interpretation in the psychotherapeutic process have established a formal understanding in the literature that has given only oblique reference to the actual experience of the therapist in practice. "Interpretation" has for the most part been left dangling above and beyond the immediate grasp of the novice therapist as an objectified ideal of great importance. Practical application of this intervention has suffered due to a mystification of its lived nature in the traditional literature. The current qualitative research study is a …

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Cirrhosis In The Trauma Victim --- Effect On Mortality-Rates, Glen Tinkoff, Michael Rhodes, Daniel Diamond, Joseph F. Lucke Jan 1990

Cirrhosis In The Trauma Victim --- Effect On Mortality-Rates, Glen Tinkoff, Michael Rhodes, Daniel Diamond, Joseph F. Lucke

Joseph Lucke

To evaluate the impact cirrhosis has on survival the records of 40 cirrhotic trauma victims from the registries of two Level 1 trauma centers were reviewed and probability of survival calculated using the TRISS methodology. Mechanism of injury, anatomic location, involvement of single or multiple sites, presence of ascites, elevations in serum glutamic oxaloacetic transaminase (SGOT), alkaline phosphatase, serum bilirubin, prothrombin time (PT), and hypoalbuminemia were tabulated for each patient. Contingency tables were created for injury and hepatic parameters, as related to survival, and subjected to chi square analysis. Loglinear analysis was performed on all significant parameters to evaluate the …

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Art, Science, Areté, Neil Greenberg Jan 1988

Art, Science, Areté, Neil Greenberg

Neil Greenberg

No abstract provided.

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The Biases And Mean Squared Errors Of Estimators Of Multinormal Squared Multiple Correlation, Joseph F. Lucke, Susan E. Embretson Jan 1984

The Biases And Mean Squared Errors Of Estimators Of Multinormal Squared Multiple Correlation, Joseph F. Lucke, Susan E. Embretson

Joseph Lucke

The sample squared multiple correlation coefficient, $R^{2}$ is known to have certain unsatisfactory properties as an estimator of the population squared multiple correlation. Hence, numerous adjusted estimators based on functions of $1-R^{2}$ have been proposed. We examine the biases and mean squared errors of five adjusted estimators as well as $R^{2}$. General results are given for estimators linear in $1-R^{2}$, and four such estimators are examined in detail. In addition, a quadratic estimator and the minimum variance unbiased estimator are examined. Comparisons among these estimators are made in terms of absolute bias and mean squared error.

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Medicine , Sociology, Aand The Economic Costs Of Hbp In The Black Community, Aubrey W. Bonnett Dec 1979

Medicine , Sociology, Aand The Economic Costs Of Hbp In The Black Community, Aubrey W. Bonnett

Aubrey W. Bonnett

No abstract provided.

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Ethological Considerations In The Experimental Study Of Lizard Behavior, Neil Greenberg Jan 1978

Ethological Considerations In The Experimental Study Of Lizard Behavior, Neil Greenberg

Neil Greenberg

The importance of an ethological approach to the experimental study of an unfamiliar species is described and several of its problems discussed. The selection of units of behavior is a crucial first step in the development of a behavior inventory. The correlation of a behavioral unit with a particular context is necessary to ascribe function to that to that unit and to develop an ethogram. Methods of studying lizards under controlled conditions are described and discussed. Constraints on behavior that must be considered in an experimental study include the microclimate and its thermal qualities, food and water, shelter utilization, and …

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