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Full-Text Articles in Medicine and Health Sciences

Comprehensive Analysis Of The Retinal Cell Contributions To The Human Erg, Christopher W. Tyler May 2023

Comprehensive Analysis Of The Retinal Cell Contributions To The Human Erg, Christopher W. Tyler

MODVIS Workshop

Purpose. Standard electroretinogram (ERG) protocols are largely designed to isolate the responses of the rod and cone retinal pathways, including the use of adapting backgrounds to suppress unwanted off-pathway responses. Here, we record spectral ERGs in the low-to-high mesopic sensitivity range in the absence of any adapting background in order to assess interactions between the pathways.

Methods. We have developed a comprehensive neuroanalytic model of the component structure of the ERG driven by knowledge of the underlying retinal physiology, to enhance its power as a critical diagnostic tool for a broad range of both retinal and systemic dysfunctions. The ERG …


Towards Human Retinal Cones Spatial Distribution Modeling, Matteo Paolo Lanaro, Hélène Perrier, David Coeurjolly, Victor Ostromoukhov, Alessandro Rizzi May 2019

Towards Human Retinal Cones Spatial Distribution Modeling, Matteo Paolo Lanaro, Hélène Perrier, David Coeurjolly, Victor Ostromoukhov, Alessandro Rizzi

MODVIS Workshop

No abstract provided.


Modeling Visual Enumeration Using Cumulative Link Regression., Anthony D. Cate Ph.D. May 2019

Modeling Visual Enumeration Using Cumulative Link Regression., Anthony D. Cate Ph.D.

MODVIS Workshop

Based on three core assumptions about mental representations of number, this model of visual enumeration specifies analysis methods that can identify when observers rely on different processes to estimate the numerosity of a visual display. Specifically, the model provides a clear criterion for identifying domains of numerosity that correspond to different perceptual or cognitive processes that have been described in numeracy literature, e.g. subitizing. The model predicts how the requirement to give integer responses in enumeration tasks can produce spurious discontinuities in accuracy measures that can be misidentified as evidence for a subitizing process. It is proposed that cumulative link …


Understanding Qualitative 3d Shape From Texture And Shading, Benjamin Kunsberg, Steven W. Zucker May 2018

Understanding Qualitative 3d Shape From Texture And Shading, Benjamin Kunsberg, Steven W. Zucker

MODVIS Workshop

No abstract provided.


An Active Efficient Coding Model Of The Development Of Amblyopia, Samuel Eckmann, Lukas Klimmasch, Bertram Shi, Jochen Triesch May 2018

An Active Efficient Coding Model Of The Development Of Amblyopia, Samuel Eckmann, Lukas Klimmasch, Bertram Shi, Jochen Triesch

MODVIS Workshop

No abstract provided.


Computational Modeling Of Contrast Sensitivity And Orientation Tuning In Schizophrenia, Steven M. Silverstein, Docia L. Demmin, James A. Bednar May 2017

Computational Modeling Of Contrast Sensitivity And Orientation Tuning In Schizophrenia, Steven M. Silverstein, Docia L. Demmin, James A. Bednar

MODVIS Workshop

Computational modeling is being increasingly used to understand schizophrenia, but, to date, it has not been used to account for the common perceptual disturbances in the disorder. We manipulated schizophrenia-relevant parameters in the GCAL (gain control, adaptation, laterally connected) model (Stevens et al., 2013), run using the Topographica simulator (Bednar, 2012), to model low-level visual processing changes in the disorder. Our models incorporated: separate sheets for retinal, LGN, and V1 activity; gain control in the LGN; homeostatic adaptation in V1 based on a weighted sum of all inputs and limited by a logistic (sigmoid) nonlinearity; lateral excitation and inhibition in …


Focusing On Selection For Fixation, John K. Tsotsos, Calden Wloka, Yulia Kotseruba May 2016

Focusing On Selection For Fixation, John K. Tsotsos, Calden Wloka, Yulia Kotseruba

MODVIS Workshop

Building on our presentation at MODVIS 2015, we continue in our quest to discover a functional, computational, explanation of the relationship among visual attention, interpretation of visual stimuli, and eye movements, and how these produce visual behavior. Here, we focus on one component, how selection is accomplished for the next fixation. The popularity of saliency map models drives the inference that this is solved; we suggested otherwise at MODVIS 2015. Here, we provide additional empirical and theoretical arguments. We then develop arguments that a cluster of complementary, conspicuity representations drive selection, modulated by task goals and history, leading to a …