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Articles 1 - 4 of 4
Full-Text Articles in Medicine and Health Sciences
Jesus, Jesuits, And A Little Black Magic, Brooke Sanderford
Jesus, Jesuits, And A Little Black Magic, Brooke Sanderford
Honors Colloquium
With the generosity of a Carl Goodson Travel Grant, Brooke Sanderford was given the opportunity to experience Oaxacan, Mexico, first hand. She developed a deeper understanding of the Oaxacan culture and their tribal heritage, as well as make connections with missionaries in the area with the hopes of establishing a future missionary trip.
Determining The Presence Of Bpa In Vaping Mouthpieces, Jessica Cook-Snelgrove
Determining The Presence Of Bpa In Vaping Mouthpieces, Jessica Cook-Snelgrove
Honors Theses
As more and more teenagers and young adults begin to vape, whether it be to quit smoking or to look cool, there is a potential for them to be exposed to bisphenol-A (BPA) through the plastic mouthpieces on the vapes. BPA is a molecule that is added in many plastics to make the plastic harder (Houlihan, Lunder, & Jacob, 2008). Unfortunately, BPA is structurally similar to estrogen as can be seen in Figure 1. The closeness of the structures can cause issues in humans such as cardiovascular disease, diabetes, and reproductive problems (Houlihan, Lunder, & Jacob, 2008). In recent years, …
Effectiveness And Mechanism Of Action Of Modified Porphyrins For Photodynamic Therapy Of Triple Negative Breast Cancer Cells, Hannah Brandon
Effectiveness And Mechanism Of Action Of Modified Porphyrins For Photodynamic Therapy Of Triple Negative Breast Cancer Cells, Hannah Brandon
Honors Theses
Triple negative breast cancer (TNBC) is a particularly aggressive form of breast cancer that lacks the three molecules typically targeted for treatment. Standard treatment methods leave much to be desired--the rates of metastasis and recurrence are high and the prognosis for most patients with TNBC is poor. One potential treatment for TNBC is photodynamic therapy (PDT), which uses compounds called photosensitizers that are taken up by all tissues in the body. The tumor is exposed to light, activating the photosensitizer and creating reactive oxygen species that cause cell death. This method is relatively pain-free, effective, and does not harm cells …
Killing Breast Cancer One Porphyrin At A Time, Taylor C. Lymburner
Killing Breast Cancer One Porphyrin At A Time, Taylor C. Lymburner
Honors Theses
New treatments for cancer are continuously being developed and improved. One such treatment is Photodynamic Therapy, more commonly referred to as PDT. PDT is quickly becoming more popular due to its relative lack of side effects that are present in other treatments. In PDT, light-sensitive agents are required and are activated by light in the targeted cells. There are many types of PDT agents but the one focused on in this research is a four-pyrrole ring structure known as a porphyrin. The combination of H2 TPPC with 3- amino-oxetane-3-yl-methanol created the final product ofH2TPP-Oxo-MeOH. Once the porphyrin was formed, it …