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Articles 1 - 30 of 253
Full-Text Articles in Medicine and Health Sciences
Nutritional Improvement In Critically Ill Patients On Renal Replacement Therapy: A Systematic Review, Eslam M. Agiba, Khaled M. Gaballah, Wesam E. Sultan
Nutritional Improvement In Critically Ill Patients On Renal Replacement Therapy: A Systematic Review, Eslam M. Agiba, Khaled M. Gaballah, Wesam E. Sultan
Menoufia Medical Journal
Objective To summarize the methods of nutritional improvement used in cases of protein-energy wasting in patients on maintenance hemodialysis. Data analysis Search papers, systematic reviews, and randomized clinical trials from 2004 to 2021 were reviewed in the available MEDLINE databases, which included PubMed, Medscape, Springer, Elsevier, and Science Direct. Study selection English language publications that focused on critically ill populations on renal replacement therapy requiring nutritional support were searched. Data extraction: studies by Cano and colleagues, Liu and colleagues, Oğuz and colleagues, Marsen and colleagues, Chioléro and Berger, Fiaccadori and colleagues, Ramakrishnan and Shankar, Al-Dorzi and Arabi, Bost and colleagues, …
Different Optical Coherence Tomography Parameters In Diabetic Macular Edema As Predictors Of Visual Acuity, Ahmed M. Fayed, Asmaa S.A Abu Husin, Asmaa M. Ibrahim
Different Optical Coherence Tomography Parameters In Diabetic Macular Edema As Predictors Of Visual Acuity, Ahmed M. Fayed, Asmaa S.A Abu Husin, Asmaa M. Ibrahim
Menoufia Medical Journal
Objectives The aim was to evaluate the disorganized inner retinal layers, the thickness of the outer retinal layer, and central foveal thickness using spectral domain optical coherence tomography as predictors of visual acuity (VA) in patients with diabetic macular edema (DME). Data sources Medline databases (PubMed and Medscape) were searched, and all materials available in the Internet. The search was performed on January 2022. Study selection The initial search presented 120 articles. The number of studies that met the inclusion criteria was 15. The articles included both sexes, diabetic patients aged 18 years old or above and capable of giving …
Prognostic Value Of Coronary Computed Tomography Angiography In Asymptomatic Diabetic Patients, Abdalla Mostafa, Ahmed Abdalla, Ahmed Gaafar, Mahmoud Z. Attia, Waleed Abdou
Prognostic Value Of Coronary Computed Tomography Angiography In Asymptomatic Diabetic Patients, Abdalla Mostafa, Ahmed Abdalla, Ahmed Gaafar, Mahmoud Z. Attia, Waleed Abdou
Menoufia Medical Journal
Objectives To study the prognostic value of coronary computed tomography (CT) angiography in asymptomatic diabetic patients. Background Diabetic patients have a higher prevalence of coronary artery disease (CAD) and are more likely to have silent myocardial ischemia and myocardial infarction than nondiabetics and are characterized by multivessel disease and calcified, diffuse, and distal lesions. CT coronary angiography is a safe, accurate, and reliable technique of high ability to detect CAD and estimate the degree of obstruction, number of affected arteries, and the pattern of their affection and a reliable modality for exclusion of CAD. Patients and methods This study was …
Significance Of Serum T-Cell Immunoglobulin And Mucin-Domain 3 As A Biomarker In Hepatocellular Carcinoma, Abeer M. Basiouny, Ahmed A. Sonbol, Maha A. Elbasiouny, Mai I. Abozeid, Noran T. Aboelkhair
Significance Of Serum T-Cell Immunoglobulin And Mucin-Domain 3 As A Biomarker In Hepatocellular Carcinoma, Abeer M. Basiouny, Ahmed A. Sonbol, Maha A. Elbasiouny, Mai I. Abozeid, Noran T. Aboelkhair
Menoufia Medical Journal
Objectives To study serum T-cell immunoglobulin and mucin-domain 3 (Tim-3) levels in discriminating hepatocellular carcinoma (HCC) from chronic viral hepatitis. Background HCC is the most common primary liver tumor and considered the fourth leading cause of cancer-related deaths in the developed countries. As T cells respond to persistent tumor or viral antigens, they progressively lose their functional properties with cell-surface expression of multiple inhibitory immune-checkpoint receptors. By blocking immune-checkpoint proteins, the immune system can stimulate the body's own mechanism to remain effective in its defenses against cancer. Participants and methods The study was conducted on 100 participants divided into four …
Do Apheresis Platelet Concentrates With Additive Solution Offer Advantages In Vitro Or In Therapeutic Utility?, Amira Z. Badawy, Hanan M. Bedair, Iman A. El-Tounsi, Rawhia H. El-Edel, Reham S. El-Zaiat
Do Apheresis Platelet Concentrates With Additive Solution Offer Advantages In Vitro Or In Therapeutic Utility?, Amira Z. Badawy, Hanan M. Bedair, Iman A. El-Tounsi, Rawhia H. El-Edel, Reham S. El-Zaiat
Menoufia Medical Journal
Objective To investigate the in vitro quality of room temperature stored apheresis platelet concentrates (PCs) with and without adding a platelet additive solution (PAS) and to evaluate its therapeutic utility in oncology patients. Background Several studies have highlighted using PAS as a way to improve the storage conditions of PCs. PAS is a synthetic media used in the place of plasma for platelet (PLT) storage. It is used to support metabolism, provide buffering capacity, and to protect PLTs from the storage lesion. So, it can be used to extend shelf life of PCs. To date, its application in Egyptian blood …
Study Of Autophagy-Related Gene 5 Polymorphism In Hepatocellular Carcinoma Complicating Chronic Hepatitis C, Mary A. Naguib, Mohamed S. Moustafa, Mona M. Hassouna, Yasmen A. Elhagali
Study Of Autophagy-Related Gene 5 Polymorphism In Hepatocellular Carcinoma Complicating Chronic Hepatitis C, Mary A. Naguib, Mohamed S. Moustafa, Mona M. Hassouna, Yasmen A. Elhagali
Menoufia Medical Journal
Objective To evaluate autophagy-related gene 5 (ATG5) rs510432 T/C polymorphism in hepatocellular carcinoma (HCC) complicating chronic hepatitis C. Background HCC represents a universal health problem. Among Egyptians, it ranks the fourth common cancer. Autophagy is an evolutionarily conserved intracellular recycling system that obtains a fundamental role in maintaining metabolism and homeostasis. It was widely stated that dysregulated autophagy has been implicated in cancer development. ATG5 is a key regulator involved in autophagosome formation. Patients and methods A total of 100 participants (40 patients with HCC, 40 patients with liver cirrhosis, and 20 healthy controls) were selected, …
Assessment Of Serum Level Of Interleukin-15 In Patients With Alopecia Areata, Eman M Abd El Gayed, Heba A S. Bazid, Mostafa M. Soliman, Samar M S Saleh
Assessment Of Serum Level Of Interleukin-15 In Patients With Alopecia Areata, Eman M Abd El Gayed, Heba A S. Bazid, Mostafa M. Soliman, Samar M S Saleh
Menoufia Medical Journal
Objectives To evaluate the serum level of interleukin-15 (IL-15) in patients with alopecia areata (AA) in an attempt to verify its role in the pathogenesis of the disease. Background AA is a chronic, inflammatory, and autoimmune disease, presenting with nonscarring hair loss. It is a disorder with different clinical presentations. It most commonly affects the scalp, but any hair-bearing area of the skin can be affected. Patients and methods A total number of 80 individuals were included in this case–control study; 40 patients with AA and 40 age-matched and sex-matched healthy controls. All cases were randomly selected from the Outpatient …
Protein 70 In Alopecia Areata, Aya H M. Elgendy, Eman S.E Elsayed Arafat, Mostafa M. Soliman
Protein 70 In Alopecia Areata, Aya H M. Elgendy, Eman S.E Elsayed Arafat, Mostafa M. Soliman
Menoufia Medical Journal
Background Heat shock proteins (HSPs) are proteins that are expressed under a variety of stresses. How stresses and HSPs affect alopecia areata (AA) is not fully understood. Objectives To evaluate the possible role of serum level of HSP70 in the pathogenesis of AA. Patients and methods The current work examined 43 individuals with AA and 40 analogous age-matched and sex-matched healthy controls. Patients underwent full history taking, clinical examination, and investigations (HSP70 serum levels using the enzyme-linked immunosorbent assay). The data were analyzed using the SPSS software. Results In the current study, among patients, serum HSP70 ranged between 3 and …
Efficacy And Evaluation Of Hair Transplantation In Patients With Androgenic Alopecia, Dalia M. Elsakka, Marwa S. Elkhesy, Mohamed A. Gaber
Efficacy And Evaluation Of Hair Transplantation In Patients With Androgenic Alopecia, Dalia M. Elsakka, Marwa S. Elkhesy, Mohamed A. Gaber
Menoufia Medical Journal
Objectives To evaluate the effect of follicular unit extraction (FUE) in patients with androgenic alopecia (AGA) and evaluate the satisfaction factors after surgery. Background AGA greatly influences individual's quality of life and psychological state. So, effective and available treatments are sought for patients with AGA. Among the different hair restoration methods, hair transplantation, especially FUE, is the most popular and acceptable option known for patients with hair loss. Patients and methods A prospective cohort study was conducted at the Departments of Dermatology and Plastic Surgery, Menoufia University Hospital, from June 2019 till October 2021. The study was approved by the …
Role Of The Interferon-Induced Helicase 1 Gene Polymorphism In Vitiligo: A Case-Control Pilot Study, Eman M M. Fallila, Mohammed A. Basha, Noha R. Bayomy
Role Of The Interferon-Induced Helicase 1 Gene Polymorphism In Vitiligo: A Case-Control Pilot Study, Eman M M. Fallila, Mohammed A. Basha, Noha R. Bayomy
Menoufia Medical Journal
Objectives To assess interferon-induced helicase 1 (IFIH1) gene rs1990760 single-nucleotide polymorphism (SNP) in vitiligo susceptibility and protection. Background Vitiligo is a common progressive autoimmune depigmenting disorder. Its pathogenesis remains elusive; however, it is linked to both genetic and nongenetic causes. The IFIH1 is a gene locus that is related to some autoimmune disorders. Patients and methods A case–control research study was done on 50 patients with vitiligo and 50 healthy controls who were age and sex matched. The IFIH1 rs1990760 genotypes of the patients were determined by real-time PCR (Taqman allelic discrimination). For the examined SNP, different genetic …
Evaluation Of Superoxide Dismutase Enzyme In Patients With Melasma: A Clinical And Immunohistochemical Study, Abeer S. Refay, Asmaa G. Abdou, Hesham N. Khaled, Reem A.A Elaziz Hassan
Evaluation Of Superoxide Dismutase Enzyme In Patients With Melasma: A Clinical And Immunohistochemical Study, Abeer S. Refay, Asmaa G. Abdou, Hesham N. Khaled, Reem A.A Elaziz Hassan
Menoufia Medical Journal
Objective To evaluate the role of superoxide dismutase (SOD) enzyme in melasma. Background Melasma is one of the most common acquired disorders of hyperpigmentation. SOD enzyme is upregulated in the presence of oxidative stress and can be utilized to detect it. Even though many potential etiological factors have been proposed, there is still much to learn about the pathophysiology of melasma. Patients and methods A cross-sectional study was conducted on 50 patients presenting with melasma and 50 apparently normal individuals as a control group selected from the Outpatient Clinic, Dermatology, Andrology and Sexually Transmitted Diseases Department, Faculty of Medicine, Menoufia …
Immunohistochemical Expression Of The Nuclear Factor 2 (Erythroid-Related) In Nonmelanoma Skin Cancer, Amina A M. Barakat, Marwa M. Dawoud, Mustafa A. Hammam, Ola A. Bakry
Immunohistochemical Expression Of The Nuclear Factor 2 (Erythroid-Related) In Nonmelanoma Skin Cancer, Amina A M. Barakat, Marwa M. Dawoud, Mustafa A. Hammam, Ola A. Bakry
Menoufia Medical Journal
Objectives The current study aimed to investigate the immunohistochemical expression of nuclear factor-erythroid-2-related factor 2 (NRF2) in nonmelanoma skin cancer (NMSC) [squamous cell carcinoma (SCC) and basal cell carcinoma (BCC)] and correlate its expression with the clinical and histopathological data. Background NMSC shows different behavior, growth, and metastasis; however, both BCC and SCC have a good prognosis if detected at their initial stages. BCC has lower mortality rate than SCC, which accounts for about 75% of deaths owing to NMSC. Patients and methods This study was conducted on 30 patients with NMSC and 30 age-matched and sex-matched healthy volunteers as …
Fragmented Qrs: A Novel Marker Of Cardiovascular Diseases In Patients With Erectile Dysfunction, Ahmed M. Elkersh, Alaa H. Maree, Heba A S. Bazid, Hosna El-Sayed Ali El-Nager, Mohamed B. Alghannam
Fragmented Qrs: A Novel Marker Of Cardiovascular Diseases In Patients With Erectile Dysfunction, Ahmed M. Elkersh, Alaa H. Maree, Heba A S. Bazid, Hosna El-Sayed Ali El-Nager, Mohamed B. Alghannam
Menoufia Medical Journal
Background The most common cause of erectile dysfunction (ED) is vascular insufficiency. Fragmented QRS (fQRS) is an ECG marker of myocardial ischemia in patients with coronary artery disease. Objectives To evaluate if the fQRS by ECG can be detected earlier and if it is possible to track simpler markers of cardiovascular involvement in patients with arteriogenic ED than pharmaco-penile duplex ultrasonography. Patients and methods A total of 100 patients with ED were included. They were classified according to International Index of Erectile Function-5 and subjected to detailed history taking, thorough clinical examination, and imaging studies, including pharmaco-penile duplex ultrasonography and …
Hepcidin In Psoriasis Vulgaris, Eman S.E. E. Arafat, Mostafa M. Soliman, Randa R A. Sharshar
Hepcidin In Psoriasis Vulgaris, Eman S.E. E. Arafat, Mostafa M. Soliman, Randa R A. Sharshar
Menoufia Medical Journal
Background Iron is an essential nutrient for mammals. Accelerated loss of nutrients through hyperproliferation and desquamation from the skin in psoriasis is known. Hepcidin is a recently discovered regulator of iron homeostasis and consequently in the pathogenesis of psoriasis. This study aimed to evaluate its level in psoriasis. Objective To evaluate serum level of hepcidin in patients with psoriasis vulgaris and its relation with severity of the disease. Patients and methods A total of 20 patients (12 males and eight females) who presented to the Dermatology Clinic of Menoufia University between October 2020 and January 2021 and diagnosed clinically as …
Study Of Serum Endoglin Level In Smoker And Nonsmoker Patients With Erectile Dysfunction, Eman A. Abd El Gyd, Heba S. Bazid, Mustafa A. Hammam, Yasmin A R. El Sayed
Study Of Serum Endoglin Level In Smoker And Nonsmoker Patients With Erectile Dysfunction, Eman A. Abd El Gyd, Heba S. Bazid, Mustafa A. Hammam, Yasmin A R. El Sayed
Menoufia Medical Journal
Objective This study aimed to investigate the relation between endoglin as an endothelial marker in smoker and nonsmoker patients with erectile dysfunction (ED). Background ED is a benign disorder, but it can have a significant effect on the quality of life of the patients, partners, and families. Patients and methods A prospective randomized study was conducted on 90 men having ED and attending the Andrology Clinic in Menoufia University Hospital during the period from October 2020 to March 2021. Results Regarding clinical data (P < 0.05), 33.3% of nonsmokers with ED had diabetes, whereas 36.7% of smokers with ED had diabetes and hypertension and 83.3% of control group had no commodities (P = 0.001). All smokers with ED and nonsmokers with ED had metabolic syndrome. BMI …
Role Of Dermoscopy In The Diagnosis Of Vitiligo And Evaluating Its Clinical Stability, Azza K. H. Elkazzaz, Heba Allah S E. Bazid, Hesham N. Khaled
Role Of Dermoscopy In The Diagnosis Of Vitiligo And Evaluating Its Clinical Stability, Azza K. H. Elkazzaz, Heba Allah S E. Bazid, Hesham N. Khaled
Menoufia Medical Journal
Objective To evaluate the role of dermoscopy in the confirmation of vitiligo diagnosis and evaluate its role in disease prognosis and its clinical stability. Background Vitiligo is an acquired disorder characterized by circumscribed depigmented macules and patches with or without leukotrichia. Dermoscopy by magnifying the clinical image many folds allows the appreciation of subtle features invisible to the naked eye. Dermoscopy has been reported to be beneficial in certain circumstances in vitiligo, including diagnosis of early vitiligo, assessment of the stage of the disease, assessment of treatment response by detecting clinically in apparent leukotrichia, especially in the segmental variant, and …
Relation Between Tissue Lipocalin-2 Expression And Kidney Dysfunction In Chronic Kidney Disease Patients, Ahmed R. Tawfeek, Hanaa G. Faheem Sakr, Heba A. S. Eldeen Khail Bazid, Iman A F. Seleit, Rania A A. Hassanin
Relation Between Tissue Lipocalin-2 Expression And Kidney Dysfunction In Chronic Kidney Disease Patients, Ahmed R. Tawfeek, Hanaa G. Faheem Sakr, Heba A. S. Eldeen Khail Bazid, Iman A F. Seleit, Rania A A. Hassanin
Menoufia Medical Journal
Background Chronic kidney disease (CKD) is known to induce a wide spectrum of cutaneous manifestations, which has been widely reported in the literature. Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin, is a protein secreted mainly by activated neutrophils. Objectives To evaluate the relation between LCN2 expression in normal skin samples with clinical parameters of CKD. Patients and methods This cross-sectional study was conducted on 20 CKD patients. All patients were subjected to history taking and complete medical examination. Punch biopsy of normal skin was taken from each patient for the detection of immunohistochemical expression of LCN2 protein. Results LCN2 …
Study Of The Frequency Of Meningitis After Spinal Anesthesia For Various Surgical Procedures, Ayman A. Sakr, Hosam I. Mohammed, Mohamed A. Sakr, Ragaa M. Elsayed, Reem M. El-Kholy
Study Of The Frequency Of Meningitis After Spinal Anesthesia For Various Surgical Procedures, Ayman A. Sakr, Hosam I. Mohammed, Mohamed A. Sakr, Ragaa M. Elsayed, Reem M. El-Kholy
Menoufia Medical Journal
Objective This study aimed to the frequency, presentation, and outcome of meningitis after spinal anesthesia for various surgical procedures. Background Postoperative bacterial meningitis may result in prolonged hospitalization, an extended course of antibiotics, and possibly mortality. Patients and methods This cross-sectional study included 141 patients referred to El Mahala El Kobra Fever Hospital complaining of symptoms and signs of meningeal irritation after spinal anesthesia for different surgical procedures. The patients were classified according to the clinical, laboratory, and cerebrospinal fluid (CSF) analysis and culture into two groups: group I: positive for meningitis that included 79 patients, and group II: negative …
Long Noncoding Rna As A Diagnostic Tool In Vascular Complication Of Diabetes, Mohamed El Sayed Sakr, Nabil A. El Kafrawy, Shaimaa K. Zewain, Shimaa A. Refaat, Shimaa A. Hassanein
Long Noncoding Rna As A Diagnostic Tool In Vascular Complication Of Diabetes, Mohamed El Sayed Sakr, Nabil A. El Kafrawy, Shaimaa K. Zewain, Shimaa A. Refaat, Shimaa A. Hassanein
Menoufia Medical Journal
Background At present, there is really no unique biomarker for detecting diabetes-related vascular complications. As a result, it is critical to investigate specific biomarkers for diagnosing, detecting, and catching the early stages of disease progression. Objectives To analyze the relationship of long noncoding RNA in patients with asymptomatic atherosclerotic diabetic. Patients and methods This case–control study included 312 participants recruited from Menoufia University Hospitals' Internal Medicine Outpatient Clinics and Inpatient Departments and divided into two groups: group I was the diabetic with subclinical atherosclerosis group, which included 176 patients with type 2 diabetes mellitus, with the carotid intima-media thickness assessed …
Serum And Cerebrospinal Fluid Heparin-Binding Protein Levels In Differentiating Acute Bacterial From Nonbacterial Meningitis, Aida S. Markous, Ayman M. El-Lehleh, Eman A. Bader, Moamena S. Elhamouly
Serum And Cerebrospinal Fluid Heparin-Binding Protein Levels In Differentiating Acute Bacterial From Nonbacterial Meningitis, Aida S. Markous, Ayman M. El-Lehleh, Eman A. Bader, Moamena S. Elhamouly
Menoufia Medical Journal
Background Early diagnosis of meningitis and differentiation of bacterial from nonbacterial plays an important role in the effective treatment of patients. Objectives To evaluate the role of serum and cerebrospinal fluid (CSF) heparin-binding protein (HBP) in early diagnosis of acute bacterial meningitis (ABM) and its efficacy in differentiating acute bacterial from non-BM. Patients and methods This was a case–control study performed between January 2020 and April 2021. It included 65 patients with ABM, 48 patients with acute non-BM, and 20 healthy persons. Diagnosis of meningitis was based on history, clinical criteria, and CSF examination and culture. HBP was measured using …
Prevalence And Risk Factors Of Overweight And Obesity Among Adolescents: A Cross-Sectional Study, Fatma A. El-Srrigy, Hala M. Elmoselhy, Samar Abd El-Rhman Alkaffas
Prevalence And Risk Factors Of Overweight And Obesity Among Adolescents: A Cross-Sectional Study, Fatma A. El-Srrigy, Hala M. Elmoselhy, Samar Abd El-Rhman Alkaffas
Menoufia Medical Journal
Objective This study aimed to assess the prevalence and risk factors of overweight and obesity among adolescents. Background Obesity is a significant public health concern affecting more than half-a-billion people worldwide, with increasing its prevalence among adolescents. Its consequences include hypertension, diabetes mellitus, hyperlipidemia, coronary-artery diseases, and some cancers. Patients and methods This cross-sectional study included 200 adolescents aged 10–19 years old from two preparatory schools and two secondary schools in Shebin El-kom district (one city and one village selected randomly). Data were collected through a predesigned questionnaire. Participants were evaluated for sociodemographic characteristics, nutritional, family history, and physical activity. …
Predictors Of Diabetic Foot Ulcer Severity Among Patients Attending Menoufia University Hospital, Egypt, Ayah M. Barakat, Hala M. Shaheen, Manal H Mohamed Al-Siad, Nora A. Khalil, Yahia M. Alkhateep
Predictors Of Diabetic Foot Ulcer Severity Among Patients Attending Menoufia University Hospital, Egypt, Ayah M. Barakat, Hala M. Shaheen, Manal H Mohamed Al-Siad, Nora A. Khalil, Yahia M. Alkhateep
Menoufia Medical Journal
Background Diabetic foot ulcer (DFU) results in major medical, financial, and social burden for the patients, their families, and society. Objective To assess the severity of DFU and identify the predictors of ulcer severity among the studied patients. Patients and methods A cross-sectional study of 70 DFU patients was undertaken. They were evaluated through a structured self-administrated questionnaire composed of four parts (sociodemographic data, diabetes-related data, knowledge, and practice about foot care) followed by physical examination to assess DFU severity. Results According to Wagner's classification, grade 2 DFU was the most prevalent among the studied group (42.9%), Followed by Grade …
Effect Of Diet And Exercise Program On Clinical And Metabolic Features Of Polycystic Ovarian Syndrome, Amira A. Fathey, Asmaa A. Mohammed, Hala M. Shaheen, Nora A. Khalil, Safa H. Alkalash, Taghreed M. Farahat
Effect Of Diet And Exercise Program On Clinical And Metabolic Features Of Polycystic Ovarian Syndrome, Amira A. Fathey, Asmaa A. Mohammed, Hala M. Shaheen, Nora A. Khalil, Safa H. Alkalash, Taghreed M. Farahat
Menoufia Medical Journal
Objectives To assess the effect of a diet and exercise program on clinical and metabolic features among women with polycystic ovary syndrome (PCOS). Background PCOS affects 5–10% of reproductive-aged women and is associated with reproductive and metabolic dysfunctions. Obesity worsens the presentation of PCOS, and weight management (weight loss or prevention of excess weight gain) is proposed as an initial treatment strategy, best achieved through lifestyle changes including diet and exercise interventions. Patients and methods This study was conducted in two stages: the first stage was a cross-sectional study, and the second stage was an interventional prospective study. A total …
Validity Of New Insulin Resistance Indices In Correlation With Atherosclerotic Cardiovascular Disease, Ahmed M. Mohamed, Mai A. Kamel, Nabil Abd El-Fatah El-Kafrawy, Reham S. El Zaiat
Validity Of New Insulin Resistance Indices In Correlation With Atherosclerotic Cardiovascular Disease, Ahmed M. Mohamed, Mai A. Kamel, Nabil Abd El-Fatah El-Kafrawy, Reham S. El Zaiat
Menoufia Medical Journal
Objective To study the validity of triglyceride–glucose (TyG) index and triglyceride/high-density lipoprotein (TG/HDL) ratio as insulin resistance (IR) markers and correlating them with atherosclerotic cardiovascular disease (ASCVD). Background IR is a metabolic disorder that leads to metabolic syndrome, which is an important risk factor for ASCVD; early detection by noninvasive, easy and cheap markers is important. Patients and methods A cross-sectional study carried out on 81 participants attending to the outpatient clinic and inpatient ward in the Internal Medicine Department. Full history, physical examination, and biochemical profiles were obtained. Participants were classified according to the Framingham Wilson score into two …
Acute Kidney Injury In Hospitalized Patients With Covid-19, Heba El-Sayed Kasem, Mahmoud A. Kora, Mahmoud M. Emara, Shaban E E. Mohamed
Acute Kidney Injury In Hospitalized Patients With Covid-19, Heba El-Sayed Kasem, Mahmoud A. Kora, Mahmoud M. Emara, Shaban E E. Mohamed
Menoufia Medical Journal
Objectives To investigate the severity, risk factors, and outcomes of acute kidney injury (AKI) in hospitalized patients with coronavirus disease 2019 (COVID-19). Background COVID-19 has been associated with elevated incidence of AKI. More search is required to confirm the role of COVID-19 as an independent risk factor for AKI. Patients and methods This retrospective cohort study included data collected from medical records, patients' follow-up, and charts of 100 patients who were diagnosed with COVID-19 infection by a positive RT-PCR assay of a specimen collected via nasopharyngeal swab between the first of December 2020 and 31 May 2021 in COVID-19 isolation …
Phenotypic And Molecular Identification Of Carbapenemase-Producing Escherichia Coli And Klebsiella Isolates, Mabrok M. Ghonaim, Rawhia H. El-Adel, Reem M. Elkholy, Samar S. Salman
Phenotypic And Molecular Identification Of Carbapenemase-Producing Escherichia Coli And Klebsiella Isolates, Mabrok M. Ghonaim, Rawhia H. El-Adel, Reem M. Elkholy, Samar S. Salman
Menoufia Medical Journal
Background Carbapenemase-producing carbapenem-resistant Enterobacteriaceae are a significant problem worldwide that causes life-threatening infections. Objectives To evaluate the performance of the phenotypic method [modified carbapenem-inactivation method (mCIM) and EDTA-modified carbapenem inactivation method (eCIM)] tests to detect carbapenemase production compared with the genotypic method (real-time PCR) in Escherichia coli and Klebsiella species strains that were isolated from patients in the Menoufia University Hospitals. Methods E. coli and Klebsiella species strains were isolated from patients in different departments of the Menoufia University Hospitals. The isolated strains were tested by the phenotypic method (mCIM and eCIM) tests to detect carbapenemase production, and screened by …
Psychiatric Comorbidities In Human-Immunodeficiency Virus-Infected/-Acquired Immunodeficiency-Syndrome Patients, Ahmed N. Ramadan, Ahmed M.M. S. Azzam, Ayman A. El-Hadad, Mohamed A. Gabber
Psychiatric Comorbidities In Human-Immunodeficiency Virus-Infected/-Acquired Immunodeficiency-Syndrome Patients, Ahmed N. Ramadan, Ahmed M.M. S. Azzam, Ayman A. El-Hadad, Mohamed A. Gabber
Menoufia Medical Journal
Objective The aim of this study was to study the psychiatric comorbidities, signs, symptoms, and general functioning in HIV-infected/AIDS patients. Background Co-occurring psychiatric disease has direct clinical impact on patients infected with HIV, such as worsening quality of life and rapid progression of HIV/AIDS symptoms. Patients and methods This study was carried out in Shebin Elkom tropical hospital 'outpatient clinics' on 30 patients with positive HIV infection/AIDS patients. The tools used are mental-state examination, Hamilton Anxiety Scale, Hamilton Depression Scale, drug-of-abuse urine-screen test, and Karnofsky Performance Scale Test. Results There was a statistically significant association between the presence of depression …
Intravenous Thrombolytic Therapy In Acute Ischemic Stroke: Study Of Barriers And Outcome Of An Egyptian Experience, Aktham I. Alemam, Ibrahim E. Alahmar, Khaled H. Afifi, Marwa H A. Khallaf
Intravenous Thrombolytic Therapy In Acute Ischemic Stroke: Study Of Barriers And Outcome Of An Egyptian Experience, Aktham I. Alemam, Ibrahim E. Alahmar, Khaled H. Afifi, Marwa H A. Khallaf
Menoufia Medical Journal
Objectives To identify barriers against thrombolytic therapy of acute ischemic stroke (AIS) and to evaluate its efficacy and complications in Egypt. Background Tissue plasminogen activator is the only FDA-approved thrombolytic therapy for AIS. However, its use in Egypt is below best practice benchmarks. Patients and methods In a cohort observational study, 120 patients with AIS were recruited from the stroke unit of Menoufia University Hospitals and were divided into three groups: group A included 40 patients who received intravenous thrombolysis (IVT), group B included 40 patients who were eligible but did not receive IVT, and group C included 40 patients …
Assessment Of Cognitive Function In Patients With Sleep Apnea Syndrome, Gehan A. Abdelaal, Hend R. Omara, Mai M. El-Kalashy, Nehad B. Abdelaty
Assessment Of Cognitive Function In Patients With Sleep Apnea Syndrome, Gehan A. Abdelaal, Hend R. Omara, Mai M. El-Kalashy, Nehad B. Abdelaty
Menoufia Medical Journal
Background Obstructive sleep apnea (OSA) can negatively affect patients' physical and psychological functioning, as well as their quality of life. A major consequence of OSA is impaired cognitive functioning. Indeed, several studies have shown that OSA mainly leads to deficits in executive functions, attention, and memory. Objectives To assess cognitive function in patients with sleep apnea syndrome. Patients and methods This prospective study was done on 70 patients with sleep apnea syndrome who were referred to Chest and Neurology Departments, Menoufia University Hospital, in the period from January 2021 to April 2022. The study was done after written consents from …
A Decreased Need For Systemic Psoriasis Treatment With Associated Use Of Serotonin Reuptake Inhibitors, Ahmed N. Ramadan, Ayman A. El-Hadad, Azza G. A. Farag, Ibrahim H M. Al Fayoumy
A Decreased Need For Systemic Psoriasis Treatment With Associated Use Of Serotonin Reuptake Inhibitors, Ahmed N. Ramadan, Ayman A. El-Hadad, Azza G. A. Farag, Ibrahim H M. Al Fayoumy
Menoufia Medical Journal
Objectives The aim was to investigate whether psoriasis is affected by the use of selective serotonin reuptake inhibitors (SSRIs). Background Psoriasis is an immune-mediated dermatological disorder with psychological and social morbidity. Stress plays an important role in psoriasis, including the negative somato–psychiatric rebound occurring in the disease. Patients and methods This prospective, analytic, cohort study was conducted at the Neuropsychiatry Department, Faculty of Medicine, Menoufia University, and included 64 patients with psoriasis attending Outpatient Clinic of Dermatology Department, Faculty of Medicine, Menoufia University Hospitals, between November 2020 and October 2021, after approval from the Research and Ethics Committee. Patients were …