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Full-Text Articles in Medicine and Health Sciences
Effect Of Rheumatoid Arthritis Treatment On The Posterior Segment Of The Eye, Abdelkawy Moghazy, Ahmed S. Fayed, Heba A. R. Rizk, Moataz El-Sawy
Effect Of Rheumatoid Arthritis Treatment On The Posterior Segment Of The Eye, Abdelkawy Moghazy, Ahmed S. Fayed, Heba A. R. Rizk, Moataz El-Sawy
Menoufia Medical Journal
Objective The aim of the study was to evaluate the influence of rheumatoid arthritis (RA) treatment on the posterior segment of the eye using spectral-domain optical coherence tomography. Background RA is a common chronic autoimmune systemic inflammatory disease that primarily affects mainly small joints. It may affect many parts of the eye, such as conjunctiva, cornea, sclera, uvea, choroid, and retina. Patients and methods The study included 44 RA patients (22 on methotrexate and 22 on etanercept), and 21 healthy controls. Results A significant increase in choroidal thickness in the RA group compared with the control group. There were no …
Relation Between Neuropathic Pain And Serum Levels Of Vitamin D In Egyptian Patients With Rheumatoid Arthritis, Enas A. Abdelaleem, Mervat I. Abdelazeem, Rabab A. Mohamed, Shaimaa S. Anwar
Relation Between Neuropathic Pain And Serum Levels Of Vitamin D In Egyptian Patients With Rheumatoid Arthritis, Enas A. Abdelaleem, Mervat I. Abdelazeem, Rabab A. Mohamed, Shaimaa S. Anwar
Menoufia Medical Journal
Objectives This study aims to measure vitamin D serum levels in Egyptian patients with rheumatoid arthritis (RA) and assess its association with neuropathic pain (NP). Patients and methods The present study was conducted on 70 RA patients. NP was evaluated by the Leeds Assessment of Neuropathic Symptoms and Signs, visual analog scale (VAS) was used to assess the degree of pain, disease activity score (DAS-28) was used to assess activity, and modified health assessment questionnaire (mHAQ) was used to assess quality of life. Serum vitamin D levels were measured for all the patients by ELISA. Results RA patients with NP …
Paraoxonase-1 Enzyme Activity In Rheumatoid Arthritis Patients: Association With Carotid Intima-Media Thickness?, Ahmed R. Tawfeek, Aly M. El-Kholy, Mohamed Z. Nouh, Sabry A. Shoeib, Waleed M. Fathy
Paraoxonase-1 Enzyme Activity In Rheumatoid Arthritis Patients: Association With Carotid Intima-Media Thickness?, Ahmed R. Tawfeek, Aly M. El-Kholy, Mohamed Z. Nouh, Sabry A. Shoeib, Waleed M. Fathy
Menoufia Medical Journal
Objectives The aim was to find the relationship of biochemical determinants of paraoxonase-1 (PON1) enzyme activity with carotid intima-media thickness (IMT) as a surrogate marker of atherosclerotic cardiovascular (CV) disease risk in patients with rheumatoid arthritis (RA). Background There is strong correlation between patients with RA and CV morbidity and mortality that cannot be explained by traditional risk factors alone. And this could be due to abnormal function of high-density lipoproteins (HDL). HDL promotes cholesterol efflux, as well as protects low-density lipoprotein (LDL) against oxidation, and this ability has been referred to as an 'anti-inflammatory' function because the lipid oxidation …
Laryngeal Assessment Of Patients With Rheumatoid Arthritis Using Laryngeal Photodocumentation, Alaa Labeeb, Asmaa El-Dessouky, Eman Ezzat, Hossam El-Dessouky, Mohamed Baraka
Laryngeal Assessment Of Patients With Rheumatoid Arthritis Using Laryngeal Photodocumentation, Alaa Labeeb, Asmaa El-Dessouky, Eman Ezzat, Hossam El-Dessouky, Mohamed Baraka
Menoufia Medical Journal
Objective The aim was to assess the prevalence of dysphonia and laryngeal changes upon videolaryngoscopic examination of patients with rheumatoid arthritis (RA). Background RA effects on larynx vary from mild asymptomatic effect to life-threatening conditions. Many authors have emphasized the need of studies in different communities on its effect. In Egypt, the knowledge regarding its manifestations on the larynx, as well as its laryngeal alterations, is limited. Patients and methods A total of 79 patients diagnosed as having RA in Menoufia University Hospitals from March 2015 to March 2017 were assessed by taking history and asking about different laryngeal complaints …
Sleep Pattern Changes In Patients With Rheumatoid Arthritis, Dina R. Alsharaki, Emad E. Abd El-Hamid, Ibrahim I. El-Mahallawy, Mohamed A. Zamzam, Rana H. El-Helbawy
Sleep Pattern Changes In Patients With Rheumatoid Arthritis, Dina R. Alsharaki, Emad E. Abd El-Hamid, Ibrahim I. El-Mahallawy, Mohamed A. Zamzam, Rana H. El-Helbawy
Menoufia Medical Journal
Objective The aim of this study was to assess sleep pattern changes in patients with rheumatoid arthritis (RA). Background There is evidence that patients with RA may be at increased risk for sleep disorders, particularly obstructive sleep apnea (OSA). Sleep abnormalities have also been linked to increased pain and fatigue perception, which are common concerns in rheumatology patients. Untreated OSA with intermittent hypoxia is associated with elevated levels of systemic inflammatory markers: C-reactive protein (CRP) and proinflammatory cytokines. Patients and methods Thirty patients diagnosed as having RA, and 30 apparent healthy control participants were invited to participate in the study. …
Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand In Patients With Systemic Lupus Erythematosus, Amal F. Makled, Asmaa M. Elbrolosy, Elham A. Negm, Emad M. Elshebini, Gamalat A. Elgedawy, Mohamed A. Helwa, Wafaa A. Zahran
Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand In Patients With Systemic Lupus Erythematosus, Amal F. Makled, Asmaa M. Elbrolosy, Elham A. Negm, Emad M. Elshebini, Gamalat A. Elgedawy, Mohamed A. Helwa, Wafaa A. Zahran
Menoufia Medical Journal
The aim of this study was to study the relationship between serum level of soluble tumor necrosis factor-related apoptosis-inducing ligand (sTRAIL) and the disease activity in patients with systemic lupus erythematosus (SLE) and also to compare sTRAIL levels between patients with lupus and patients with rheumatoid arthritis as well as healthy volunteers. A search was performed in Medline databases (PubMed, Medscape, Science Direct, and EMF-Portal) and all materials available in the Internet from 2000 to 2017. The initial search presented 18 articles of which eight met the inclusion criteria. These articles studied the relation between sTRAIL and the disease activity …
Role Of Interleukin-33 In Rheumatoid Arthritis Patients From Menoufia University Hospitals, Ahmed A. Salama, Ahmed B. Mahmoud, Alaa F. Gomah, Dina R. Al-Sharaki
Role Of Interleukin-33 In Rheumatoid Arthritis Patients From Menoufia University Hospitals, Ahmed A. Salama, Ahmed B. Mahmoud, Alaa F. Gomah, Dina R. Al-Sharaki
Menoufia Medical Journal
Objectives The objective of this study was to detect the level of interleukin-33 (IL-33) in patients with rheumatoid arthritis (RA) and to explore the relationship between the level of IL-33 in the serum with the disease activity and functional performance. Background Cytokines are important mediators of immune functions in humans and animals. IL-33, a newly found IL-1 family cytokine, is involved in joint inflammation in RA. Therefore, we aimed to investigate the immunopathological roles of IL-33 in serum RA patients. Patients and methods This study was conducted on a total of 80 individuals: 60 of them were RA patients (55 …
Immunomodulatory Effect Of Mesenchymal Stem Cells On Lymphocytes Of Rheumatoid Arthritis Patients, Gehan A. Tawfeek, Heba A. Esaily, Maha A. Elbassuoni, Mai F. Mohamed Abd El Rahim Badr
Immunomodulatory Effect Of Mesenchymal Stem Cells On Lymphocytes Of Rheumatoid Arthritis Patients, Gehan A. Tawfeek, Heba A. Esaily, Maha A. Elbassuoni, Mai F. Mohamed Abd El Rahim Badr
Menoufia Medical Journal
Objectives The aim of this work was to isolate, expand mesenchymal stem cells (MSCs) from bone marrow (BM), and assess the immunomodulation potential of MSCs on T lymphocytes of patients with rheumatoid arthritis (RA). Background MSCs are multipotent adult stem cells present in all tissues. They are present in the BM, and possess remarkable immunomodulation properties that can inhibit the proliferation and function of the major immune cell populations. These unique properties make MSCs ideal candidates for clinical application in autoimmune diseases (e.g., RA). Patients and methods MSCs were cultured from BM aspirate and detected morphologically; peripheral blood (PB) mononuclear …
Association Of Janus Kinase 2 With Primary Budd-Chiari Syndrome In Egyptian Patients, Asmaa M. Rezk, Mohamed A. Mohamed, Mona F. Mahmoud
Association Of Janus Kinase 2 With Primary Budd-Chiari Syndrome In Egyptian Patients, Asmaa M. Rezk, Mohamed A. Mohamed, Mona F. Mahmoud
Menoufia Medical Journal
Objective To investigate the effect of pentoxifylline (PTX) and pioglitazone (Pg), each alone and in combination with methotrexate (MTX), on rheumatoid arthritis (RA) induced experimentally in male albino rats. Background Individuals have long feared RA as one of the most disabling types of arthritis. It is estimated that over 46 million individuals have arthritis, ~1% worldwide. Material and methods One hundred and eighty adult male albino rats were used in the present study. MTX was administered intraperitoneally at a dose of 0.25 mg/kg daily. PTX was administered intraperitoneally at a dose of 150 mg/kg/rat/day, whereas Pg was administered orally at …
Study Of The Effect Of Treatment Of Helicobacter Pylori On Rheumatoid Arthritis Activity, Abd El-Samed I. El-Hewala, Dina R. Alsharaki, Maha M. Abd El-Raof Salman, Said S A Khamis, Samar G. Soliman
Study Of The Effect Of Treatment Of Helicobacter Pylori On Rheumatoid Arthritis Activity, Abd El-Samed I. El-Hewala, Dina R. Alsharaki, Maha M. Abd El-Raof Salman, Said S A Khamis, Samar G. Soliman
Menoufia Medical Journal
Objective The aim of the study was to assess the effect of Helicobacter pylori treatment on disease activity in patients with rheumatoid arthritis. Background A triggering infectious agent has long been postulated in rheumatoid arthritis. Data on the possible role of H. pylori infection are lacking. Patients and methods Forty adult patients with established rheumatoid arthritis and dyspeptic symptoms were recruited. In all, 17 patients were H. pylori positive and 23 patients were H. pylori negative on the basis of H. pylori fecal antigen test. All infected patients were treated successfully. We evaluated the disease activity using clinical [duration of …