Medicine and Health Sciences Commons^™

Non-Pharmacological Supportive Care Interventions During Immunotherapy For People With Cancer: A Systematic Scoping Review And Future Directions, Morgan J. Farley, Brighid R. Scanlon, Megan Crichton, Ashley M. Bigaran, Amy C.M. Barnes, Nicolas H. Hart, Patsy M. Yates, Melissa L. Eastgate, Kim Alexander

Research outputs 2022 to 2026

Purpose: Immunotherapy has transformed cancer treatment and outcomes. Patients receiving immunotherapy often encounter immune-related and treatment-related adverse events, leading to substantial supportive care needs. Currently, no recommendations exist to guide the use of non-pharmacological supportive care interventions for people with cancer undergoing immunotherapy treatments. This review aims to summarise the available evidence regarding non-pharmacological supportive care strategies to inform future clinical management and research directions.

Methods: Six electronic databases (PubMed, CINAHL, EMBASE, PsycInfo, Web of Science and Scopus) were systematically searched for studies on non-pharmacological supportive care interventions for adults undergoing immunotherapy, published from October 2014 to October 2024.

Results: …

Safety Of Bioelectrical Impedance Analysis In Patients With Cardiac Implantable Electronic Devices: A Systematic Review, Leonardo J. Uribe-Cavero, Fabian A. Chavez-Ecos, Kiara Camacho-Caballero, José Carlos Grados-Pintos, Patricia Vera-Maccha, Anthony Siguas-Huasasquiche, Dinesh Sharma, Carlos J. Toro-Huamanchumo

Research outputs 2022 to 2026

Background Bioelectrical impedance analysis (BIA) is widely used to assess body composition. However, its safety in patients with cardiac implantable electronic devices (CIEDs) remains uncertain owing to potential electromagnetic interference (EMI). Objective This study aimed to evaluate potential complications associated with clinical-grade BIA use in patients with CIEDs, based on currently available evidence. Methods We conducted a systematic review of studies published up to December 26, 2024, identified through PubMed, Embase, Scopus, and the Cochrane Library. The primary outcome was the occurrence of adverse events, including EMI, device malfunction, or arrhythmias. Results Of 3668 records, 6 cohort studies (n = …

Sertraline To Reduce Recidivism In Impulsive Violent Offenders (Reinvest): A Randomised Double Blind Clinical Trial, Tony Butler, Emaediong I. Akpanekpo, Lee Knight, Kristy Robledo, David Greenberg, Andrew Ellis, Stephen Allnutt, Kay Wilhelm, Alison Jones, Rodney Scott, Bianca Ton, Luke Grant, Philip Mitchell, Ross Tynan, Jocelyn Jones, Dominic Villa, Duncan Chappell, Carolynn Dixon, Alison Churchill, Val Gebski, Tony Keech, Peter W. Schofield

Research outputs 2022 to 2026

Background: Biological studies suggest serotonin modulation via selective serotonin reuptake inhibitors (SSRIs) might reduce impulsive violence, however, robust evidence in offender populations is limited. We aimed to determine whether sertraline reduces violent reoffending compared with placebo in highly impulsive men with recurrent violent offending.

Methods: We conducted a double-blind, placebo-controlled, randomised clinical trial in community settings in New South Wales, Australia. Eligible participants were men aged 18 years or older with ≥2 prior violent convictions and a Barratt Impulsiveness Scale score ≥70. Following a 4-week single-blind active run-in phase with sertraline, participants were randomly assigned (1:1, minimization stratified by key …

The Effects Of Acute And Chronic Exercise On Lipocalin-2 In Middle-Aged And Older Adults: A Randomized Control Trial, Carlie Bauer, Marc Sim, Cassandra Smith, Rhiannon Healy, Andrew Garnham, Navabeh Zare-Kookandeh, Elizabeth Byrnes, Mary N. Woessner, Joshua R. Lewis, Itamar Levinger

Research outputs 2022 to 2026

Objective Chronically elevated circulating lipocalin-2 (LCN2) levels are implicated in poor energy regulation, increased cardio-metabolic disease risk, and poor physical function. Exercise is known to improve these factors, but whether LCN2 is modifiable by exercise is not clear. We examined the effect of acute and chronic exercise on LCN2 levels and whether this relates to glucose regulation, body composition, and physical function. Design and methods Thirty-three middle-aged and older adults (45–84 years, median body mass index 26.21 kg/m²) completed an acute high-intensity interval exercise session (HIIE). Participants were randomized to 4 weeks of high-intensity interval training (HIIT) or …

What Is Known About Asthma Care And Management For Children And Young People Under 18 Years Of Age In New Zealand. A Scoping Review, J. Blamires, M. Foster, B. Kanengoni-Nyatara

Research outputs 2022 to 2026

Introduction: Asthma is the most common chronic health condition affecting children in Aotearoa New Zealand, with Māori and Pacific children disproportionately burdened by high morbidity and inequitable care. Despite clinical guidelines and growing research, inconsistencies in diagnosis, treatment adherence, and education persist. This scoping review identifies and maps literature on care models, service delivery, education and support strategies, and experiences of children, young people, and their family/whānau in asthma care and management for those under 18 in Aotearoa New Zealand. Methods: This scoping review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses Extension for Scoping …

Determining Timeframes To Death For Imminently Dying Patients: A Retrospective Cohort Study, Tricia O’Connor, Wai Man Liu, Juliane Samara, Joanne Lewis, Karen Strickland, Catherine Paterson

Research outputs 2022 to 2026

Background: Clinicians are frequently asked ‘how long’ questions at end-of-life by patients and those important to them, yet predicting timeframes to death remains uncertain, even in the last weeks and days of life. Patients and families wish to know so they can ask questions, plan, make decisions, have time to visit and say their goodbyes, and have holistic care needs met. Consequently, this necessitates a more accurate assessment of empirical data to better inform prognostication and reduce uncertainty around time until death. The aims of this study were to determine the timeframes for palliative care patients (a) between becoming comatose …

Effects Of Short- And Long-Term Exercise Training On Cancer Cells In Vitro: Insights Into The Mechanistic Associations, Francesco Bettariga, Dennis R. Taaffe, Daniel A. Galvão, Robert U. Newton

Research outputs 2022 to 2026

Exercise is a therapeutic approach in cancer treatment, providing several benefits. Moreover, exercise is associated with a reduced risk for developing a range of cancers and for their recurrence, as well as with improving survival, even though the underlying mechanisms remain unclear. Preclinical and clinical evidence shows that the acute effects of a single exercise session can suppress the growth of various cancer cell lines in vitro. This suppression is potentially due to altered concentrations of hormones (e.g., insulin) and cytokines (e.g., tumor necrosis factor alpha and interleukin 6) after exercise. These factors, known to be involved in tumorigenesis, may …

Exercise Medicine As Adjunct Therapy During Radiation For Cancer Of The Prostate To Improve Treatment Efficacy – Protocol For The Eradicate Study: A Phase Ii Randomised Controlled Trial, Oliver Schumacher, Robert U. Newton, Colin Tang, Raphael Chee, Sjoerd B. Vos, Ronny S. Low, David Joseph, Dennis R. Taaffe, Daniel A. Galvão

Research outputs 2022 to 2026

Background: Tumour hypoxia resulting from inadequate perfusion is common in many solid tumours, including prostate cancer, and constitutes a major limiting factor in radiation therapy that contributes to treatment resistance. Emerging research in preclinical animal models indicates that exercise has the potential to enhance the efficacy of cancer treatment by modulating tumour perfusion and reducing hypoxia; however, evidence from randomised controlled trials is currently lacking. The ‘Exercise medicine as adjunct therapy during RADIation for CAncer of the prostaTE’ (ERADICATE) study is designed to investigate the impact of exercise on treatment response, tumour physiology, and adverse effects of treatment in prostate …

The Effect Of Prednisolone Ingestion And Acute Exercise On Lipocalin-2 And Its Variants In Young Men: A Pilot Randomised Crossover Study, Carlie Bauer, Rhiannon K. Patten, Qiyang Sun, Haoyun Li, Daniels Konja, Mary Woessner, Xuzhu Lin, Andrew Garnham, David L. Hare, Peter R. Ebeling, Marc Sim, Joshua R. Lewis, Yu Wang, Lewan Parker, Itamar Levinger

Research outputs 2022 to 2026

Lipocalin-2 (LCN2) has three main variants; polyaminated (hLCN2) and non-polyaminated (C87A and R81E). The polyaminated form is proposed to positively influence energy control, whereas the non-polyaminated forms negatively impact energy control in mice. Glucocorticoids negatively affect glucose regulation and exercise has a positive effect. We hypothesise that glucocorticoids will suppress, while exercise will increase hLCN2, and decrease C87A and R81E, which will be associated with improved insulin sensitivity. In a randomised crossover design, nine young healthy men (aged 27.8 ± 4.9 years; BMI 24.4 ± 2.4 kg/m2) completed 30 min of high-intensity aerobic exercise (90–95% heart rate reserve) after glucocorticoid …

Alzheimer’S Disease Biological Pet Staging Using Plasma P217+Tau, Azadeh Feizpour, Vincent Doré, Natasha Krishnadas, Pierrick Bourgeat, James D. Doecke, Ziad S. Saad, Gallen Triana-Baltzer, Simon M. Laws, Rosita Shishegar, Kun Huang, Christopher Fowler, Larry Ward, Colin Masters, Jurgen Fripp, Hartmuth Kolb, Victor Villemagne, Christopher Rowe

Research outputs 2022 to 2026

Background: Plasma phospho-tau biomarkers, such as p217+tau, excel at identifying Alzheimer’s disease (AD) neuropathology. However, their ability to substitute for tau PET to identify AD biological stage is unclear. Methods: Participants included 248 cognitively unimpaired (CU) and 227 cognitively impaired (CI) individuals, with Janssen plasma p217+tau Simoa® assay, 18F-NAV4694 Aβ-PET (A) and 18F-MK6240 tau-PET (T) data. Biological PET stages were defined according to the Revised Criteria for Diagnosis and Staging of Alzheimer’s Disease (2024): Initial (A + T-), Early (A + TMTL +), Intermediate (A + TMOD +), and Advanced (A + THIGH +). The threshold for A+ was 25 …

Cutting Through The Fog: Recognising Brain Fog As A Significant Public Health Concern, Darren Haywood, Susan L. Rossell, Nicolas H. Hart

Research outputs 2022 to 2026

Brain fog is a highly common condition that can have significant impacts on quality of life and functioning. Most people will experience a condition, illness, or infection that might result in the development of brain fog. We provide a call to action to minimise the impacts of brain fog.

Health Outcomes Of Sarcopenia: A Consensus Report By The Outcome Working Group Of The Global Leadership Initiative In Sarcopenia (Glis), Charlotte Beaudart, Julian Alcazar, Ivan Aprahamian, John A. Batsis, Yosuke Yamada, Carla M. Prado, Jean Yves Reginster, Dolores Sanchez-Rodriguez, Wee Shiong Lim, Marc Sim, Stephan Von Haehling, Jean Woo, Gustavo Duque

Research outputs 2022 to 2026

The Global Leadership Initiative in Sarcopenia (GLIS) aims to standardize the definition and diagnostic criteria for sarcopenia into one unifying, common classification. Among other actions to achieve this objective, the GLIS has organized three different working groups (WGs), with the WG on outcomes of sarcopenia focusing on reporting its health outcomes to be measured in clinical practice once a diagnosis has been established. This includes sarcopenia definitions that better predict health outcomes, the preferred tools for measuring these outcomes, and the cutoffs defining normal and abnormal values. The present article synthesizes discussions and conclusions from this WG, composed of 13 …

Summarizing Attributable Factors And Evaluating Risk Of Bias Of Mendelian Randomization Studies For Alzheimer’S Dementia And Cognitive Status: A Systematic Review And Meta-Analysis, Xiaoni Meng, Xiaochun Li, Meiling Cao, Jing Dong, Haotian Wang, Weijie Cao, Di Liu, Youxin Wang

Research outputs 2022 to 2026

Background: No effective treatment is available to delay or reverse the onset and progression of Alzheimer’s dementia (AD). Mild cognitive impairment, a clinical state between normal aging and AD, may offer the proper window for AD intervention and treatment. This systematic review aimed to summarize evidence from Mendelian randomization (MR) studies exploring factors attributable to AD and related cognitive status and to assess its credibility. Methods: We searched PubMed, Embase, MEDLINE, and the Cochrane Library to identify MR studies investigating the associations between any factor and AD and related cognitive status. The risk of bias in MR studies was evaluated …

Exploring And Validating Associations Between Six Systemic Inflammatory Indices And Ischemic Stroke In A Middle-Aged And Old Chinese Population, Yulu Zheng, Zheng Guo, Jingzheng Wang, Zhiyuan Wu, Xiaolin Chen, Yahong Zhu, Guangle Shan, Haifeng Hou, Xingang Li

Research outputs 2022 to 2026

Background: Inflammation and maladaptive immune mechanisms have been substantiated as integral components in the critical pathological processes of the injury cascade in ischemic stroke (IS). This study aimed to explore the associations between six systemic inflammatory indices and IS in a Chinese population. Methods: This was a case-control study based on the retrospective review of electronic medical records from two hospitals in Shandong Province, China. Systemic inflammatory indices, including the systemic inflammation response index (SIRI), systemic immune inflammation index (SII), pan-immune-inflammation value (PIV), neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), and lymphocyte monocyte ratio (LMR), were calculated. Logistic regression …

Cumulative Triglyceride-Glucose Index And Hypertension Risk: A Longitudinal Cohort Study, Zhaogui Wu, Dan Wu, Sichi Xu, Yan Borné, Yulong Lan, Shuohua Chen

Research outputs 2022 to 2026

Background: Prior research has established a positive association between the single-measured triglyceride-glucose (TyG) index and hypertension. Nevertheless, longitudinal studies addressing the enduring impact of TyG index on incident hypertension are lacking. This study sought to explore the association between cumulative TyG index (cum-TyG) and incident hypertension, especially obesity-related hypertension (ORHT). Methods: A total of 21,017 individuals [mean (SD) age: 48.5 ± 11.7 years, male (%): 14,544 (69.2)] without hypertension were recruited from the Kailuan Study. The cum-TyG was determined by multiplying the mean TyG index by the time intervals between successive visits. Multivariable Cox regression models were used to investigate …

Engaging Longitudinal Cohort Participants In A Research Priority Setting Process For The Raine Study, Michaela De Paolis, Saniya Abdul, Anne Mckenzie, Rebecca Glauert, Gracie Cayley, Romola S. Bucks, Diane Wood

Research outputs 2022 to 2026

Background: The Raine Study, one of the world’s longest-running multigenerational cohort studies, has consistently engaged participants in shaping specific research projects within the Raine Study. While participant involvement has been integral to study operations, there has not previously been an opportunity for participants to actively help shape the overall research agenda. The Participant Priority Setting Project (the Project) was developed to address this gap, providing a structured process to establish participant-led research priorities that will guide future study directions. Methods: The Project utilised a modified version of the James Lind Alliance (JLA) Priority Setting Partnerships (PSP) Framework to engage Generation …

Partners, Coordinators And High-Level Leaders’ Perspectives On A Consumer And Community Involvement Program In Australia: A Qualitative Evaluation Using Template Analysis, James Smith, Howard Lance, Susan Hayes

Research outputs 2022 to 2026

A Consumer and Community Involvement program located in Australia supports consumers, community members and researchers to work in partnership with health research priorities, policy and practice. The program is positioned to enhance Consumer and Community Involvement (CCI) at individual, organisational, and system levels. Partners are key to the program’s development, growth and sustainment. This study explored various partner perspectives on their involvement within the CCI program, including individuals (consumers, researchers) organisations (universities, medical research institutes) and the system level (funding organisations) alongside CCI program coordinators (delivering the program) and high-level leaders (decision-makers/executive leaders/directors). Data were collected via two focus groups …

Postinactivity Exercise Training Improves Sarcopenia Traits In 40–60-Year-Old Women Regardless Of Fortified Milk Supplementation, Joanne Trezise, Ricardo M. Lima, Sally D. Poppitt, Aaron C. Fanning, Amanda Devine, Anthony J. Blazevich

Research outputs 2022 to 2026

Background: The term sarcopenia was introduced to describe the age-related decline in muscle mass, but current definitions also include measures of muscle strength and function. Menopause increases sarcopenia risk and may exacerbate the adverse effects of physical inactivity. Exercise training is a potent stimulus to restore muscle health, and nutritional supplementation can further improve the outcomes. The purposes of this study were to examine the changes in a set of sarcopenia-related phenotypes induced by a 14-day step-reduction period followed by a 12-week exercise training programme, with or without fortified milk supplementation in healthy 40–60-year-old females, and to determine whether menopausal …

Impact Of Exercise In Patients With Pancreatic Cancer Across Different Treatment Phases: A Systematic Review, Linda Toniolo, Anita Borsati, Cristina Crespo-Garcia, Diana Giannarelli, Christian Ciurnelli, Gloria Adamoli, Lorenzo Belluomini, Ilaria Trestini, Daniela Tregnago, Federico Schena, Robert U. Newton, Salvatore Paiella, Roberto Salvia, Michele Milella, Sara Pilotto, Alice Avancini

Research outputs 2022 to 2026

Background: With a dismal prognosis of 8–10 % 5-year survival since diagnosis, pancreatic cancer remains one of the most aggressive oncological diseases. This work aimed to evaluate the effects of exercise medicine on safety and feasibility, physical fitness, body composition, patient-reported outcomes, and clinical outcomes across different treatment phases in patients with pancreatic cancer. Method: PubMed, Cochrane, and Scopus databases were systematically screened to identify single-arm studies and randomized/non-randomized controlled trials investigating a physical exercise intervention in patients with pancreatic cancer. The RoB 2 and ROBINS-I tools were used to evaluate study quality for randomized and non-randomized studies, respectively. Qualitative …

Neutrophil Gelatinase-Associated Lipocalin And Fibrinogen-To-Albumin Ratio Are Indicators Of Kidney Disease In Sickle Cell Disease Patients With Microalbuminuria: A Multicentre Case-Control Study In Ghana, Stephen Twumasi, Enoch Odame Anto, Christian Obirikorang, Richard Kobina Dadzie Ephraim, Benedict Sackey, Vivian Paintsil, Richard Owusu Ansah, Alfred Effah, Allwell Adofo Ayirebi, Angela Opoku, Godfred Yawson Scott, Leslie Osei, Joyce Duku, Emmanuel Asafo Adjei, Lilian Antwi Boateng

Research outputs 2022 to 2026

Background: Neutrophil gelatinase-associated lipocalin (NGAL) is present in secondary granules of neutrophils and it is a relatively newly recognized marker of kidney diseases. The fibrinogen-to-albumin ratio (FAR) is a marker of inflammation but its diagnostic value has not been determined in sickle cell disease patients with kidney diseases. This study investigated the diagnostic roles of serum neutrophil gelatinase-associated lipocalin (sNGAL) and FAR for kidney diseases in steady-state adult sickle cell disease (SCD) patients. Methods: This study employed a prospective case-control design and recruited 104 SCD participants and 80 non-SCD patients. Participants’ information was thoroughly documented using a structured questionnaire and …

Ceftriaxone Use Evaluation At The Medical Ward, Jigme Dorji Wangchuck National Referral Hospital In Bhutan: A Retrospective Analytical Study, Kezang Tshering, Mongal Singh Gurung, Sonam Wangda, Pelden Chejor

Research outputs 2022 to 2026

Objectives Ceftriaxone is the most commonly prescribed cephalosporin antibiotic in hospital settings. The overall prescribing compliance with the national antibiotic guidelines remained unassessed at Jigme Dorji Wangchuk National Referral Hospital (JDWNRH), Bhutan. Methods A retrospective analytical study was conducted by evaluating the medical records of patients who received ceftriaxone between January and December 2020 in the Medical Ward, JDWNRH. Data were analyzed using the Statistical Package for the Social Sciences, version 26. Results A total of 201 (17.82%) patients, with a mean age of 54.83 years (SD ± 20.93), received ceftriaxone, and pneumonia (49.25%) was the most frequently documented indication. …

Source-Specific Nitrate Intake And Incident Dementia In The Danish Diet, Cancer And Health Study, Catherine P. Bondonno, Pratik Pokharel, Dorit Wielandt Erichsen, Liezhou Zhong, Jörg Schullehner, Cecilie Kyrø, Kirsten Frederiksen, Peter Fjeldstad Hendriksen, Frederik Dalgaard, Lauren C. Blekkenhorst, Stephanie R. Rainey-Smith, Samantha L. Gardener, Torben Sigsgaard, Ole Raaschou-Nielsen, Anne Tjønneland, Jonathan M. Hodgson, Christina C. Dahm, Anja Olsen, Nicola P. Bondonno

Research outputs 2022 to 2026

Introduction: Dietary nitrate, through conversion to nitric oxide, which supports vascular and nervous system function, may lower dementia risk but may also form neurodegenerative N-nitrosamines, depending on the nitrate source. Methods: We investigated associations between source-specific nitrate and nitrite intake and incident and early-onset dementia (< 65 years) in 54,804 dementia-free participants from the Danish Diet, Cancer and Health Cohort Study over ∼27 years. Nitrate and nitrite intakes were derived from food frequency questionnaires and nitrate and nitrite databases. Results: Higher plant-sourced nitrate intake was non-linearly associated with lower rates of incident dementia (fifth vs first quintile hazard ratio 95% confidence interval: 0.90 [0.83, 0.98]), while increased risk was seen for higher intakes of animal-sourced, additive-permitted meat-sourced, and tap water-sourced nitrate. Similar associations were seen for source-specific nitrite intake and were more pronounced for early-onset dementia. No clear effect modification was observed. Discussion: These findings highlight the importance of nitrate source in dementia risk and warrant further investigation. Highlights: Plant nitrate is associated with a lower risk of incident and early-onset dementia. Animal and tap water nitrate are associated with an increased risk of dementia. Encouraging consumption of plant-based nitrate sources may lower risk of dementia.

Comparison Of Respiratory Responses To Exercise Under Different Heat-Stressful Environments Between Oral Contraceptive And Naturally Menstruating Ovulating Female Athletes, Nanako Hayashi, Toby Mündel, Tze Huan Lei, Claire Badenhorst

Research outputs 2022 to 2026

The present study conducted a secondary analysis of previous data (Lei et al., 2017, 2019) to compare exercise-induced respiratory responses under heat stress between the early follicular (EF)/ quasi -EF and mid-luteal (ML)/ quasi -ML phases in naturally menstruating and oral contraceptive pill (OCP)-using female athletes. Additionally, the study aimed to examine the associations between respiratory responses, thermoregulation, and hormonal profiles within each group. Sixteen endurance-trained female athletes participated: eight with a natural menstrual cycle (NM group) and eight using OCP (OCP group). Each participant completed four trials, comprising fixed-intensity cycling (at 125 and 150 W) followed by a 30-min …

As Effective As You Perceive It: The Relationship Between Chatgpt’S Perceived Effectiveness And Mental Health Stigma, Scott N. Hannah, Deirdre Drake, Christopher D. Huntley, Joanne M. Dickson

Research outputs 2022 to 2026

Individuals are increasingly using artificial intelligence chatbots, such as ChatGPT, to seek conversational support for their personal mental health difficulties. Heightened concerns about mental health stigma may make anonymous, on-demand chatbot interactions more appealing for some than traditional face-to-face support. This study examined if using ChatGPT-4 for personal mental health difficulties is associated with two distinct forms of stigma, anticipated stigma and self-stigma. Our main aim was to investigate if the perceived effectiveness of ChatGPT use for mental health issues mediates the relationship between ChatGPT usage and anticipated stigma and self-stigma. The sample comprised 73 participants, mostly undergraduate psychology students. …

A Cross-Sectional Audit Of The Australian Community Food Environment Highlights The Prominent Role Of Chain Food Outlets, Claire Elizabeth Pulker, Lucy Meredith Butcher, Frith Klug, Clare Whitton, Gina S.A. Trapp

Research outputs 2022 to 2026

Background: Food retail and food service outlets can be part of a chain, or independently operated. Chain food outlets are likely to have the most influence over community food environments but have not been routinely identified in studies which map and monitor access to food, highlighting an important knowledge gap. This study aimed to identify the food retail and food service outlets present within metropolitan Perth, including presence of chain and independent food outlets; and examine differences across local governments. Methods: A nutrition-focused classification framework was applied to all food businesses registered by 32 local governments in Perth, Western Australia, …

Nurses’ And Midwives’ Job Satisfaction And Retention During Covid-19: A Scoping Review, Laura Hynes, Sadie Geraghty, Sheena Mcchlery, Aisling Smyth, Reeti Brar, Karen Clark-Burg

Research outputs 2022 to 2026

Background: The COVID-19 pandemic focused attention on the previously well-documented world-wide shortage of nurses and midwives. The pandemic accentuated this crisis, which resulted in nurses and midwives questioning their roles and their careers. The impact of the pandemic on job satisfaction and the intention of nurses and midwives to stay has not been adequately explored. Aim: The aim of this scoping review was to identify and map the literature that describes the intrinsic and extrinsic factors that influenced nurses’ and midwives’ job satisfaction and intent to stay or leave their employment or profession during the COVID-19 pandemic. Method: This scoping …

State Of Stroke Rehabilitation In Australia: A Who Stars Assessment To Identify Strengths And Gaps Across Policy, Practice And Funding, Lauren J. Christie, Erin Godecke, Maddison Smith, Katharine Scrivener, Kelvin Hill, Joosup Kim, Maria Crotty, Dominique A. Cadilhac, Angela Dos Santos, Natasha A. Lannin

Research outputs 2022 to 2026

Purpose of Review: Rehabilitation following stroke is a complex series of assistive and catalytic interventions enabling a survivor to recover and adapt to their stroke. To achieve adaptation, rehabilitation should supplement healthcare across the continuum, however comprehensive evidence on the provision of stroke rehabilitation in Australia is lacking. The aim of this paper was to describe stroke rehabilitation provision, collecting data using the World Health Organisation (WHO) template for rehabilitation information collection (TRIC). Data were analysed descriptively to complete the Systematic Assessment of Rehabilitation Situation (STARS) assessment. Recent Findings: Challenges include inadequacies in reporting and poor data integration between state- …

Promises And Perils Of Generative Artificial Intelligence: A Narrative Review Informing Its Ethical And Practical Applications In Clinical Exercise Physiology, Oscar Lederman, Alessandro Llana, James Murray, Robert Stanton, Ritesh Chugh, Darren Haywood, Amanda Burdett, Geoff Warman, Joanne Walker, Nicolas H. Hart

Research outputs 2022 to 2026

Generative Artificial Intelligence (GenAI) is transforming various sectors, including healthcare, offering both promising opportunities and notable risks. The infancy and rapid development of GenAI raises questions regarding its effective, safe, and ethical use by health professionals, including clinical exercise physiologists. This narrative review aims to explore existing interdisciplinary literature and summarise the ethical and practical considerations of integrating GenAI into clinical exercise physiology practice. Specifically, it examines the ‘promises’ of improved exercise programming and healthcare delivery, as well as the ‘perils’ related to data privacy, person-centred care, and equitable access. Recommendations for the responsible integration of GenAI in clinical exercise …

A National Survey Of Osteopaths’ Conceptions Of Practice In France: Structural Validity Of The Osteo-Taqfr And The Tendency Toward Technical Rationality, Oliver P. Thomson, Loïc Treffel, Agathe Wagner, Erwann Jacquot, Jerry Draper-Rodi, Chantal Morin, Brett Vaughan

Research outputs 2022 to 2026

Background: Despite the growing popularity of osteopathy in France, little is known about how French osteopaths conceptualise key aspects of their practice, including skills, knowledge, and decision-making. This study aimed to adapt and validate the Osteopaths' Therapeutic Approaches Questionnaire (Osteo-TAQ) for use in a French osteopathic population (Osteo-TAQfr) and to examine the professional profile and core elements of clinical practice among French osteopaths. The first objective was to establish the psychometric properties of the Osteo-TAQfr within a French osteopathic population. The second aim was to explore French osteopaths’ conceptions of practice and their approach to patient care, thereby contributing to …

Interventions, Programmes And Resources That Address Culturally And Linguistically Diverse Consumer And Carers’ Cancer Information Needs: A Mixed Methods Systematic Review, Lisa Whitehead, Deborah Kirk, Pelden Chejor, Weiting Liu, Minh Nguyen, Caroline Balczer, Charlene Lan, Melissa Evans

Research outputs 2022 to 2026

Background: Culturally and linguistically diverse (CaLD) consumers and carers have been identified as experiencing high levels of unmet needs relating to information and support across the cancer journey. This review identified and evaluated the effectiveness of strategies to meet the cancer information needs of consumers and carers from CaLD backgrounds. Methods: This review followed Joanna Briggs Institute (JBI) methodology for systematic reviews. Databases searched included MEDLINE, CINAHL Ultimate, PsycINFO and AMED, ProQuest Dissertations and Theses, and GreyNet. Published and unpublished studies between 2013 - May 2024 on interventions, programmes or resources developed for adults (aged 18 years and over) from …