Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Sports Sciences (750)
- Public Health (745)
- Nursing (639)
- Medical Specialties (489)
- Diseases (435)
-
- Medical Sciences (338)
- Social and Behavioral Sciences (276)
- Oncology (244)
- Neurosciences (193)
- Mental and Social Health (180)
- Rehabilitation and Therapy (180)
- Public Health Education and Promotion (167)
- Dietetics and Clinical Nutrition (158)
- Nursing Midwifery (127)
- Psychology (127)
- Analytical, Diagnostic and Therapeutic Techniques and Equipment (122)
- Life Sciences (121)
- Epidemiology (120)
- Psychiatry and Psychology (109)
- Occupational Health and Industrial Hygiene (85)
- Education (75)
- Physical Sciences and Mathematics (71)
- Maternal, Child Health and Neonatal Nursing (67)
- Endocrinology, Diabetes, and Metabolism (64)
- Communication Sciences and Disorders (54)
- Sociology (51)
- Chemicals and Drugs (49)
- Medical Genetics (49)
- Diagnosis (48)
- Keyword
-
- [RSTDPub] (405)
- Exercise (170)
- Human (135)
- Australia (126)
- Cancer (124)
-
- Article (108)
- Physical activity (107)
- Male (96)
- Alzheimer's disease (95)
- Female (95)
- Dementia (90)
- Mental health (87)
- Nursing (85)
- Western Australia (78)
- Children (77)
- Resistance training (76)
- Adult (74)
- Alzheimer’s disease (74)
- Quality of life (74)
- COVID-19 (70)
- Controlled study (69)
- Systematic review (68)
- Biomarkers (67)
- Diet (65)
- Health (65)
- Public health (65)
- Rehabilitation (65)
- Prostate cancer (64)
- Stroke (63)
- Cognition (62)
- Publication Year
- Publication
-
- Research outputs 2022 to 2026 (2302)
- Research outputs 2014 to 2021 (1525)
- Theses: Doctorates and Masters (465)
- Theses : Honours (227)
- Research outputs pre 2011 (102)
-
- Research outputs 2013 (101)
- Research outputs 2012 (90)
- Research outputs 2011 (40)
- Journal of the Australian Indigenous HealthInfoNet (38)
- ECU Posters (16)
- Australian Journal of Teacher Education (11)
- Research Datasets (11)
- Australian Indigenous HealthBulletin (10)
- Australian eHealth Informatics and Security Conference (10)
- ECU Research Week (10)
- 'INSCAPE' - ARTCAP November 13-16, 2003 (6)
- eCULTURE (5)
- Australian Information Security Management Conference (4)
- EDU-COM International Conference (2)
- Reports accepted as research outputs (1)
- School of Psychology and Social Science Presentations (1)
- Publication Type
- File Type
Articles 4381 - 4410 of 4977
Full-Text Articles in Medicine and Health Sciences
Multiple Γ-Secretase Product Peptides Are Coordinately Increased In Concentration In The Cerebrospinal Fluid Of A Subpopulation Of Sporadic Alzheimer's Disease Subjects, Saori Hata, Miyako Taniguchi, Yi Piao, Takeshi Ikeuchi, Anne Fagan, David Holtzman, Randall Bateman, Hamid Sohrabi, Ralph Martins, Sam Gandy, Katsuya Urakami, Toshiharu Suzuki
Multiple Γ-Secretase Product Peptides Are Coordinately Increased In Concentration In The Cerebrospinal Fluid Of A Subpopulation Of Sporadic Alzheimer's Disease Subjects, Saori Hata, Miyako Taniguchi, Yi Piao, Takeshi Ikeuchi, Anne Fagan, David Holtzman, Randall Bateman, Hamid Sohrabi, Ralph Martins, Sam Gandy, Katsuya Urakami, Toshiharu Suzuki
Research outputs 2012
Background: Alcadeinα (Alcα) is a neuronal membrane protein that colocalizes with the Alzheimer's amyloid-β precursor protein (APP). Successive cleavage of APP by β- and γ-secretases generates the aggregatable amyloid-β peptide (Aβ), while cleavage of APP or Alcα by α- and γ-secretases generates non-aggregatable p3 or p3-Alcα peptides. Aβ and p3-Alcα can be recovered from human cerebrospinal fluid (CSF). We have previously reported alternative processing of APP and Alcα in the CSF of some patients with sporadic mild cognitive impairment (MCI) and AD (SAD). Results: Using the sandwich enzyme-linked immunosorbent assay (ELISA) system that detects total p3-Alcα, we determined levels of …
Systematic Review Of Predictive Performance Of Injury Severity Scoring Tools, Hideo Tohira, Ian Jacobs, David Mountain, Nicholas Gibson, Allen Yeo
Systematic Review Of Predictive Performance Of Injury Severity Scoring Tools, Hideo Tohira, Ian Jacobs, David Mountain, Nicholas Gibson, Allen Yeo
Research outputs 2012
Many injury severity scoring tools have been developed over the past few decades. These tools include the Injury Severity Score (ISS), New ISS (NISS), Trauma and Injury Severity Score (TRISS) and International Classification of Diseases (ICD)-based Injury Severity Score (ICISS). Although many studies have endeavored to determine the ability of these tools to predict the mortality of injured patients, their results have been inconsistent. We conducted a systematic review to summarize the predictive performances of these tools and explore the heterogeneity among studies. We defined a relevant article as any research article that reported the area under the Receiver Operating …
Effects Of Lowering Body Temperature Via Hyperhydration, With And Without Glycerol Ingestion And Practical Precooling On Cycling Time Trial Performance In Hot And Humid Conditions, Megan Ross, Nikki Jeacocke, Paul Laursen, David Martin, Christopher Abbiss, Louise Burke
Effects Of Lowering Body Temperature Via Hyperhydration, With And Without Glycerol Ingestion And Practical Precooling On Cycling Time Trial Performance In Hot And Humid Conditions, Megan Ross, Nikki Jeacocke, Paul Laursen, David Martin, Christopher Abbiss, Louise Burke
Research outputs 2012
Background: Hypohydration and hyperthermia are factors that may contribute to fatigue and impairment of endurance performance. The purpose of this study was to investigate the effectiveness of combining glycerol hyperhydration and an established precooling technique on cycling time trial performance in hot environmental conditions.Methods: Twelve well-trained male cyclists performed three 46.4-km laboratory-based cycling trials that included two climbs, under hot and humid environmental conditions (33.3 ± 1.1°C; 50 ± 6% r.h.). Subjects were required to hyperhydrate with 25 g.kg-1 body mass (BM) of a 4°C beverage containing 6% carbohydrate (CON) 2.5 h prior to the time trial. On two occasions, …
Evaluation Of A Multi-Marker Immunomagnetic Enrichment Assay For The Quantification Of Circulating Melanoma Cells, James Freeman, Elin Gray, Michael Milward, Robert Pearce, Melanie Ziman
Evaluation Of A Multi-Marker Immunomagnetic Enrichment Assay For The Quantification Of Circulating Melanoma Cells, James Freeman, Elin Gray, Michael Milward, Robert Pearce, Melanie Ziman
Research outputs 2012
Background: Circulating melanoma cells (CMCs) are thought to be valuable in improving measures of prognosis in melanoma patients and may be a useful marker of residual disease to identify non-metastatic patients requiring adjuvant therapy. We investigated whether immunomagnetic enrichment targeting multiple markers allows more efficient enrichment of CMCs from patient peripheral blood than targeting a single marker. Furthermore, we aimed to determine whether the number of CMCs in patient blood was associated with disease stage.Methods: We captured CMCs by targeting the melanoma associated markers MCSP and MCAM as well as the melanoma stem cell markers ABCB5 and CD271, both individually …
Can Exercise Ameliorate Treatment Toxicity During The Initial Phase Of Testosterone Deprivation In Prostate Cancer Patients? Is This More Effective Than Delayed Rehabilitation?, Robert Newton, Dennis Taaffe, Nigel Spry, Prue Cormie, Suzanne Chambers, Robert Gardiner, David Shum, David Joseph, Daniel Galvao
Can Exercise Ameliorate Treatment Toxicity During The Initial Phase Of Testosterone Deprivation In Prostate Cancer Patients? Is This More Effective Than Delayed Rehabilitation?, Robert Newton, Dennis Taaffe, Nigel Spry, Prue Cormie, Suzanne Chambers, Robert Gardiner, David Shum, David Joseph, Daniel Galvao
Research outputs 2012
Background: There has been substantial increase in use of androgen deprivation therapy as adjuvant management of prostate cancer. However, this leads to a range of musculoskeletal toxicities including reduced bone mass and increased skeletal fractures compounded with rapid metabolic alterations, including increased body fat, reduced lean mass, insulin resistance and negative lipoprotein profile, increased incidence of cardiovascular and metabolic morbidity, greater distress and reduced quality of life. Numerous research studies have demonstrated certain exercise prescriptions to be effective at preventing or even reversing these treatment toxicities. However, all interventions to date have been of rehabilitative intent being implemented after a …
Adjusting For Under-Identification Of Aboriginal And/Or Torres Strait Islander Births In Time Series Produced From Birth Records: Using Record Linkage Of Survey Data And Administrative Data Sources, D Lawrence, D Christensen, F Mitrou, Glenn Draper, G Davis, S Mckeown, Daniel Mcaullay, G Pearson, S R Zubrick
Adjusting For Under-Identification Of Aboriginal And/Or Torres Strait Islander Births In Time Series Produced From Birth Records: Using Record Linkage Of Survey Data And Administrative Data Sources, D Lawrence, D Christensen, F Mitrou, Glenn Draper, G Davis, S Mckeown, Daniel Mcaullay, G Pearson, S R Zubrick
Research outputs 2012
Background: Statistical time series derived from administrative data sets form key indicators in measuring progress in addressing disadvantage in Aboriginal and Torres Strait Islander populations in Australia. However, inconsistencies in the reporting of Indigenous status can cause difficulties in producing reliable indicators. External data sources, such as survey data, provide a means of assessing the consistency of administrative data and may be used to adjust statistics based on administrative data sources. Methods. We used record linkage between a large-scale survey (the Western Australian Aboriginal Child Health Survey), and two administrative data sources (the Western Australia (WA) Register of Births and …
A Randomised Trial Of Robotic And Open Prostatectomy In Men With Localised Prostate Cancer, Robert Gardiner, J Yaxley, G Coughlin, N Dunglison, S Occhipinti, S Younie, R Carter, S Williams, R J Medcraft, Bennett Nigel, M F Lavin, Suzanne Chambers
A Randomised Trial Of Robotic And Open Prostatectomy In Men With Localised Prostate Cancer, Robert Gardiner, J Yaxley, G Coughlin, N Dunglison, S Occhipinti, S Younie, R Carter, S Williams, R J Medcraft, Bennett Nigel, M F Lavin, Suzanne Chambers
Research outputs 2012
Background: Prostate cancer is the most common male cancer in the Western world however there is ongoing debate about the optimal treatment strategy for localised disease. While surgery remains the most commonly received treatment for localised disease in Australia more recently a robotic approach has emerged as an alternative to open and laparoscopic surgery. However, high level data is not yet available to support this as a superior approach or to guide treatment decision making between the alternatives. This paper presents the design of a randomised trial of Robotic and Open Prostatectomy for men newly diagnosed with localised prostate cancer …
Prolonged Sedentary Time And Physical Activity In Workplace And Non-Work Contexts: A Cross-Sectional Study Of Office, Customer Service And Call Centre Employees, A A Thorp, G N Healy, E Winkler, B K Clark, P A Gardiner, N Owen, David Dunstan
Prolonged Sedentary Time And Physical Activity In Workplace And Non-Work Contexts: A Cross-Sectional Study Of Office, Customer Service And Call Centre Employees, A A Thorp, G N Healy, E Winkler, B K Clark, P A Gardiner, N Owen, David Dunstan
Research outputs 2012
Background: To examine sedentary time, prolonged sedentary bouts and physical activity in Australian employees from different workplace settings, within work and non-work contexts.Methods: A convenience sample of 193 employees working in offices (131), call centres (36) and customer service (26) was recruited. Actigraph GT1M accelerometers were used to derive percentages of time spent sedentary (<100 counts per>minute; cpm), in prolonged sedentary bouts (≥20 minutes or ≥30 minutes), light-intensity activity (100-1951 cpm) and moderate-to-vigorous physical activity (MVPA; ≥1952 cpm). Using mixed models adjusted for confounders, these were compared for: work days versus non-work days; work hours versus non-work hours (work days only); …
Multigene Interactions And The Prediction Of Depression In The Wisconsin Longitudinal Study, N S Roetker, J A Yonker, C. Lee, V Chang, J J Basson, C L Roan, T S Hauser, R M Hauser, Craig Atwood
Multigene Interactions And The Prediction Of Depression In The Wisconsin Longitudinal Study, N S Roetker, J A Yonker, C. Lee, V Chang, J J Basson, C L Roan, T S Hauser, R M Hauser, Craig Atwood
Research outputs 2012
Objectives: Single genetic loci offer little predictive power for the identification of depression. This study examined whether an analysis of gene-gene (G x G) interactions of 78 single nucleotide polymorphisms (SNPs) in genes associated with depression and agerelated diseases would identify significant interactions with increased predictive power for depression. Design: A retrospective cohort study. Setting: A survey of participants in the Wisconsin Longitudinal Study. Participants: A total of 4811 persons (2464 women and 2347 men) who provided saliva for genotyping; the group comes from a randomly selected sample of Wisconsin high school graduates from the class of 1957 as well …
Assessing Sprint Paddle Ability In Competitive Surfers, Joseph Coyne, Jeremy Sheppard
Assessing Sprint Paddle Ability In Competitive Surfers, Joseph Coyne, Jeremy Sheppard
Research outputs 2012
No abstract provided.
Strength A Strong Predictor Of Paddling Performance In Competitive Surfers, Jeremy Sheppard, Phil Mcnamara, Mark Osborne, Mark Andrews, Dale Chapman
Strength A Strong Predictor Of Paddling Performance In Competitive Surfers, Jeremy Sheppard, Phil Mcnamara, Mark Osborne, Mark Andrews, Dale Chapman
Research outputs 2012
No abstract provided.
Comparison Of Running Times During Reactive Offensive And Defensive Agility Protocols, Tania Spiteri, Sophia Nimphius, Jodie Wilkie
Comparison Of Running Times During Reactive Offensive And Defensive Agility Protocols, Tania Spiteri, Sophia Nimphius, Jodie Wilkie
Research outputs 2012
No abstract provided.
A Brief Examination Of Strength And Paddle-Conditioning Considerations For Competitive Surfers, Jeremy Sheppard, Phil Walshe, Joseph Coyne
A Brief Examination Of Strength And Paddle-Conditioning Considerations For Competitive Surfers, Jeremy Sheppard, Phil Walshe, Joseph Coyne
Research outputs 2012
No abstract provided.
Reliability And Validity Of Unilateral And Bilateral Isometric Strength Measures Using A Customised, Portable Apparatus, Nicolas Hart, Sophia Nimphius, Jodie Wilkie, Robert Newton
Reliability And Validity Of Unilateral And Bilateral Isometric Strength Measures Using A Customised, Portable Apparatus, Nicolas Hart, Sophia Nimphius, Jodie Wilkie, Robert Newton
Research outputs 2012
No abstract provided.
Influence Of Brain-Derived Neurotrophic Factor Genetic Polymorphisms On The Ages Of Onset For Heroin Dependence In A Chinese Population, Chao Meng, Jie Lan, Youxin Wang, Manshu Song, Xuan Gao, Longjin Ran, Moira Sim, Wei Wang
Influence Of Brain-Derived Neurotrophic Factor Genetic Polymorphisms On The Ages Of Onset For Heroin Dependence In A Chinese Population, Chao Meng, Jie Lan, Youxin Wang, Manshu Song, Xuan Gao, Longjin Ran, Moira Sim, Wei Wang
Research outputs 2012
Aim: The study aims at evaluating the association between brain-derived neurotrophic factor (BDNF) gene polymorphisms and heroin-dependent patients in the Chinese population. Three polymorphisms of the BDNF-gene (rs10835210, rs16917234, and rs6265) in 486 heroin-dependent patients and in 226 healthy controls were genotyped for analyzing the association of these polymorphisms with age of onset of heroin dependence. We defined the healthy cases as “unknown phenotype” and used the endophenotype (behavior traits) to stratify the heroin dependents group on the basis of self-reporting traits for examining the association between BDNF polymorphisms (rs10835210, rs16917234, and rs6265) and heroin dependence. Results: Allelic distributions of …
The Genetic Associations And Epistatic Effects Of The Ccr5 Promoter And Ccr2-V64i Polymorphisms On Susceptibility To Hiv-1 Infection In A Northern Han Chinese Population, Jiapeng Lu, Aijuan Sheng, Youxin Wang, Ling Zhang, Jingjing Wu, Manchu Song, Yan He, Xinwei Yu, Feifei Zhao, Yezhou Liu, Shuang Shao, Jie Lan, Hao Wu, Wei Wang
The Genetic Associations And Epistatic Effects Of The Ccr5 Promoter And Ccr2-V64i Polymorphisms On Susceptibility To Hiv-1 Infection In A Northern Han Chinese Population, Jiapeng Lu, Aijuan Sheng, Youxin Wang, Ling Zhang, Jingjing Wu, Manchu Song, Yan He, Xinwei Yu, Feifei Zhao, Yezhou Liu, Shuang Shao, Jie Lan, Hao Wu, Wei Wang
Research outputs 2012
The outcome of human immunodeficiency virus (HIV)-1 infection and course to AIDS are variable among individuals. Both chemokine receptor 5 (CCR5) and CCR2 gene polymorphisms play essential roles in the susceptibility of HIV-1 infection. To investigate the main and epistatic effects of the CCR5 promoter and CCR2-V64I polymorphisms on HIV-1 infection in the Northern Han Chinese, subjects of 91 HIV-1-infected patients and 91 health controls were recruited. Single-nucleotide polymorphisms (SNPs) in the CCR5 promoter region and CCR2-V64I variants were genotyped. In the single-locus analysis, CCR5 58755-G and CCR5 59653-T alleles were significantly associated with HIV-1 infection (odds ratio [OR]=0.529, 95% …
Psycho-Educational Group Intervention For Family Caregivers Of Hospitalized Palliative Care Patients: Pilot Study, Peter Hudson, Elizabeth Lobb, Kristina Thomas, Rachel Zorden, Tom Trauer, Karen Quinn, Anne Williams, Michael Summers
Psycho-Educational Group Intervention For Family Caregivers Of Hospitalized Palliative Care Patients: Pilot Study, Peter Hudson, Elizabeth Lobb, Kristina Thomas, Rachel Zorden, Tom Trauer, Karen Quinn, Anne Williams, Michael Summers
Research outputs 2012
Background: Family caregivers of patients requiring palliative care commonly experience physical, social, and psychological burdens. Although family caregivers are acknowledged as valid service recipients of palliative care, many have unmet needs, and systematic reviews have shown there are limited evidence-based supportive interventions. Objectives: This study aimed to develop and pilot test a psycho-educational group education program delivered in the inpatient specialist palliative care setting and designed to prepare primary family caregivers for the role of supporting a relative receiving hospital-based palliative care. Methods: (1) Development of education session and delivery protocol by the research team and expert panel; (2) pilot …
Olfactory Discrimination Predicts Cognitive Decline Amongst Community-Dwelling Older Adults, Hamid Sohrabi, Kristyn Bates, Michael Weinborn, Anb Johnston, A Bahramian, Kevin Taddei, Simon Laws, Mark Rodrigues, Michael Morici, Matthew Howard, Georgia Martins, A Mackay-Sim, Se Gandy, Ralph Martins
Olfactory Discrimination Predicts Cognitive Decline Amongst Community-Dwelling Older Adults, Hamid Sohrabi, Kristyn Bates, Michael Weinborn, Anb Johnston, A Bahramian, Kevin Taddei, Simon Laws, Mark Rodrigues, Michael Morici, Matthew Howard, Georgia Martins, A Mackay-Sim, Se Gandy, Ralph Martins
Research outputs 2012
The presence of olfactory dysfunction in individuals at higher risk of Alzheimer’s disease has significant diagnostic and screening implications for preventive and ameliorative drug trials. Olfactory threshold, discrimination and identification can be reliably recorded in the early stages of neurodegenerative diseases. The current study has examined the ability of various olfactory functions in predicting cognitive decline in a community-dwelling sample. A group of 308 participants, aged 46–86 years old, were recruited for this study. After 3 years of follow-up, participants were divided into cognitively declined and non-declined groups based on their performance on a neuropsychological battery. Assessment of olfactory functions …
Olfactory Discrimination Predicts Cognitive Decline Among Community-Dwelling Older Adults, Hamid Sohrabi, Kristyn Bates, Mg Weinborn, A N Johnston, A Bahramian, Kevin Taddei, Simon Laws, Mark Rodrigues, Michael Morici, Matthew Howard, Georgia Martins, A Mackay-Sim, Se Gandy, Ralph Martins
Olfactory Discrimination Predicts Cognitive Decline Among Community-Dwelling Older Adults, Hamid Sohrabi, Kristyn Bates, Mg Weinborn, A N Johnston, A Bahramian, Kevin Taddei, Simon Laws, Mark Rodrigues, Michael Morici, Matthew Howard, Georgia Martins, A Mackay-Sim, Se Gandy, Ralph Martins
Research outputs 2012
The presence of olfactory dysfunction in individuals at higher risk of Alzheimer's disease has significant diagnostic and screening implications for preventive and ameliorative drug trials. Olfactory threshold, discrimination and identification can be reliably recorded in the early stages of neurodegenerative diseases. The current study has examined the ability of various olfactory functions in predicting cognitive decline in a community-dwelling sample. A group of 308 participants, aged 46-86 years old, were recruited for this study. After 3 years of follow-up, participants were divided into cognitively declined and non-declined groups based on their performance on a neuropsychological battery. Assessment of olfactory functions …
Adherence To A Mediterranean Diet And Alzheimer's Disease Risk In An Australian Population, Samantha Gardener, Y Gu, Stephanie Rainey-Smith, J B Keogh, P M Clifton, S L Mathieson, Kevin Taddei, Alinda Mondal, Vanessa Ward, N Scarmeas, M Barnes, K Ellis, R Head, C 0 Masters, D Ames, S 0 Macaulay, C 0 Rowe, C Szoeke, Ralph Martins
Adherence To A Mediterranean Diet And Alzheimer's Disease Risk In An Australian Population, Samantha Gardener, Y Gu, Stephanie Rainey-Smith, J B Keogh, P M Clifton, S L Mathieson, Kevin Taddei, Alinda Mondal, Vanessa Ward, N Scarmeas, M Barnes, K Ellis, R Head, C 0 Masters, D Ames, S 0 Macaulay, C 0 Rowe, C Szoeke, Ralph Martins
Research outputs 2012
The Mediterranean diet (MeDi), due to its correlation with a low morbidity and mortality for many chronic diseases, has been widely recognised as a healthy eating model. We aimed to investigate, in a cross-sectional study, the association between adherence to a MeDi and risk for Alzheimer’s disease (AD) and mild cognitive impairment (MCI) in a large, elderly, Australian cohort. Subjects in the Australian Imaging, Biomarkers and Lifestyle Study of Ageing cohort (723 healthy controls (HC), 98 MCI and 149 AD participants) completed the Cancer Council of Victoria Food Frequency Questionnaire. Adherence to the MeDi (0- to 9-point scale with higher …
Intense Physical Activity Is Associated With Cognitive Performance In The Elderly, Belinda Brown, Jeremiah Peiffer, Hamid Sohrabi, Alinda Mondal, Veer Bala Gupta, Stephanie Rainey-Smith, Kevin Taddei, S Burnham, K Ellis, C Szoeke, C L Masters, D Ames, C Rowe, Ralph Martins
Intense Physical Activity Is Associated With Cognitive Performance In The Elderly, Belinda Brown, Jeremiah Peiffer, Hamid Sohrabi, Alinda Mondal, Veer Bala Gupta, Stephanie Rainey-Smith, Kevin Taddei, S Burnham, K Ellis, C Szoeke, C L Masters, D Ames, C Rowe, Ralph Martins
Research outputs 2012
Numerous studies have reported positive impacts of physical activity on cognitive function. However, the majority of these studies have utilised physical activity questionnaires or surveys, thus results may have been influenced by reporting biases. Through the objective measurement of routine levels of physical activity via actigraphy, we report a significant association between intensity, but not volume, of physical activity and cognitive functioning. A cohort of 217 participants (aged 60-89 years) wore an actigraphy unit for 7 consecutive days and underwent comprehensive neuropsychological assessment. The cohort was stratified into tertiles based on physical activity intensity. Compared with individuals in the lowest …
The Trajectories And Correlation Between Physical Limitation And Depression In Elderly Residents Of Beijing, 1992-2009, Xia Li, Wei Wang, Qi Gao, Lijuan Wu, Yanxia Luo, Zhe Tang, Xiuhua Guo
The Trajectories And Correlation Between Physical Limitation And Depression In Elderly Residents Of Beijing, 1992-2009, Xia Li, Wei Wang, Qi Gao, Lijuan Wu, Yanxia Luo, Zhe Tang, Xiuhua Guo
Research outputs 2012
Background Physical limitation and psychological distress have been reported to be related, but studies describing the change of instrumental activities of daily living (IADLs) and depression syndrome over time or exploring the link pattern for their development are limited. The study was to assess distinctive patterns for the development of physical limitation and depression and to explore their correlation to form a proper prevention strategy. Methods Dual trajectory analysis was conducted using data from the Beijing Longitudinal Study of Aging (BLSA) 1992–2009 hosted by Xuanwu hospital for subjects with full information on depression and physical limitation for all available visits. …
Suboptimal Health: A New Health Dimension For Translational Medicine, Wei Wang, Yuxian Yan
Suboptimal Health: A New Health Dimension For Translational Medicine, Wei Wang, Yuxian Yan
Research outputs 2012
Background One critical premise of disease-related biomarkers is the definition of the counterpart normality. Contrary to pre-clinical models that can be carefully tailored according to scientific need, heterogeneity and uncontrollability is the essence of humans in health studies. Fully characterization of consistent parameters that define the normal population is the basis to individual differences normalization irrelevant to a given disease process. Self claimed normal status may not represent health because asymptomatic subjects may carry chronic diseases or diseases at their early stage such as cancer, diabetes and hypertension. Methods This paper exemplifies the characterization of the suboptimal health status (SHS) …
Sirtuin-1 Mediates The Obesity Induced Risk Of Common Degenerative Diseases: Alzheimer's Disease, Coronary Artery Disease And Type 2 Diabetes, Ian Martins, Andrea Wilson, Wei Ling Lim, Simon Laws, Stephanie Fuller, Ralph Martins
Sirtuin-1 Mediates The Obesity Induced Risk Of Common Degenerative Diseases: Alzheimer's Disease, Coronary Artery Disease And Type 2 Diabetes, Ian Martins, Andrea Wilson, Wei Ling Lim, Simon Laws, Stephanie Fuller, Ralph Martins
Research outputs 2012
Obesity, especially at mid-life, is a major risk factor for atherosclerosis, insulin resistance and the metabolic syndrome, which in turn contrib- ute to coronary artery disease (CAD), Type 2 diabetes and Alzheimer’s disease (AD). The rise in overweight and obesity in all societies is prompting intense research into the causes and effects of the condition. Obesity disrupts many body systems including glucose and lipid me- tabolism, circadian rhythms and liver function. It also causes or increases inflammation and oxi- dative stress. Within cells, the endoplasmic re- ticulum (ER) appears to be particularly suscep- tible to such metabolic disruption. Sirtuin 1 …
Assessment And Training Of Muscular Force And Power Qualities Of The Lower Limb Using Traditional And Cluster Loading, Keir Hansen
Assessment And Training Of Muscular Force And Power Qualities Of The Lower Limb Using Traditional And Cluster Loading, Keir Hansen
Theses: Doctorates and Masters
It is widely accepted that lower body muscular force and power capabilities are of significant importance to many athletic tasks. Thus the assessment and training of these qualities are a key focus in both sports science and strength and conditioning practice. The purpose of this thesis was firstly to investigate previously discussed but poorly researched methods of assessing force and power characteristics of the lower limb particularly focusing on the analysis of the force-time and power-time curves during the rebound jump squat, and secondly, to investigate the effectiveness of cluster loading, an alternative resistance training paradigm, in training for lower …
Covert Violence In Nursing: A Western Australian Experience, Susette Bakker
Covert Violence In Nursing: A Western Australian Experience, Susette Bakker
Theses: Doctorates and Masters
Covert violence in the workplace has been extensively theorized amongst social scientists as having negative effects on the worker’s self esteem, job satisfaction and stress, resulting in increased absenteeism and a reduction in productivity, and yet it continues to fester in nursing. The purpose of this research was twofold. The first was to answer the question, ‘What are the characteristics of covert violence experienced by Western Australian nurses?’ and through the description of Western Australian nurses’ experience of covert violence and describe the characteristics related to this to form a definition of covert violence. The second question was ‘What are …
Finite Element Analysis Of Stress Distribution Within Metal-On-Metal Joint Replacements, Yujing Liu
Finite Element Analysis Of Stress Distribution Within Metal-On-Metal Joint Replacements, Yujing Liu
Theses: Doctorates and Masters
Demand for joint replacements is rising in Australia, driven by a sharp increase in the number of joint problems associated with population aging and obesity. In artificial joints, delamination or failure within the coatings occurs when the stress reaches a critical level, resulting in large wear debris particles appearing on the contact surface between the head and the cup. The process has been described as due to a stress-corrosion-cracking mechanism. Under the same loading, stress increases when the contact area decreases, which happens in the vicinity of wear debris. As such, once wear debris is generated, a catastrophic process could …
A Kinanthropometric Analysis Of Accurate And Inaccurate Kickers: Implications For Kicking Accuracy In Australian Football, Nicolas H. Hart
A Kinanthropometric Analysis Of Accurate And Inaccurate Kickers: Implications For Kicking Accuracy In Australian Football, Nicolas H. Hart
Theses: Doctorates and Masters
A paucity of research exists investigating the potential relationship between the technical and temporal strategy of accurate and inaccurate kickers in response to physical parameters modifiable by athletic conditioning. While recent studies have produced improvements in performance when kicking for distance following structured resistance training interventions, no studies have examined the influence of such interventions on the enhancement of kicking accuracy. It was therefore the purpose of this thesis to extend scientific understanding of those mechanisms which might underpin accurate kicking performances through examining kinanthropometric, strength and muscularity profiles of accurate and inaccurate kickers in Australian Football using a series …
The Experiences Of Cancer Survivors As They Transition From Chemotherapy Treatment To Life After Cancer, Violet Platt
The Experiences Of Cancer Survivors As They Transition From Chemotherapy Treatment To Life After Cancer, Violet Platt
Theses: Doctorates and Masters
This study explored and described the experience of people with a diagnosis of cancer, as they transitioned from life as a chemotherapy patient to life after treatment as a cancer survivor. The purpose of this study was to ultimately improve the care of people as they transitioned into life after completion of chemotherapy treatment. There is minimal information related to this phase of the cancer trajectory, therefore this study was intentionally exploratory and descriptive. To achieve the proposed outcome a two-phased approach was undertaken. In Phase One a qualitative approach was followed using Grounded Theory to the descriptive level of …
Causes And Effects Of Physical Injuries To Prison Officers Employed In A High Risk And High Need Offender Management Environment In Western Australia, Bigboy Ngwenya
Theses: Doctorates and Masters
Prison Officers (POs) involved in high need offender management frequently face risks that could affect their health, safety and wellbeing. Several studies have shown that direct client centred violence, inadequate management systems and the general nature of prison environments are major factors impacting on the well being of POs (Fisher & Gunnison, 2001; Kiekbusch, Price, & Theis, 2003; Mitchell, Mackenzie, Styve, & Gover, 2000).There is limited literature on causes and effects of physical injuries on this group of law enforcements officers. This is the first study conducted in Western Australia (WA) that investigated the causes and effects of physical injuries …