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Articles 3481 - 3510 of 4977
Full-Text Articles in Medicine and Health Sciences
Neuromuscular Factors Contributing To Reductions In Muscle Force After Repeated, High-Intensity Muscular Efforts, Benjamin J. C. Kirk
Neuromuscular Factors Contributing To Reductions In Muscle Force After Repeated, High-Intensity Muscular Efforts, Benjamin J. C. Kirk
Theses: Doctorates and Masters
Fatigue can accumulate sufficiently to limit muscular force production during repeated, forceful muscle contractions, including those that occur in the occupational, clinical and athletic settings. Fatigue during such efforts is likely to result from disturbances to multiple processes in the nervous system and muscle. However, previous research examining the mechanisms underpinning fatigue have typically required subjects to perform low-level constant-force contractions or to repeat maximal efforts in a single set format. Such tasks do not translate well to occupational, daily living or athletic situations where high-intensity, yet submaximal, repeated efforts may be performed in work bouts (or sets) with brief …
The Effect Of Maximal Isometric Training On Doublet-Induced Force Enhancement And Its Relationship With Changes In Voluntary Rate Of Force Development, David Vernon Murray
The Effect Of Maximal Isometric Training On Doublet-Induced Force Enhancement And Its Relationship With Changes In Voluntary Rate Of Force Development, David Vernon Murray
Theses: Doctorates and Masters
Motor unit double discharges (i.e. doublets), which are excitatory potentials that occur at shorter-than-normal intervals (e.g. 5-10 ms) during normal muscle activation, are known to cause muscle force to exceed that predicted from a standard, linear summation of twitch forces. However, although a marked increase in the occurrence of motor unit doublets at the onset of a contraction has been observed after explosive-type exercise training, and has been correlated with changes in RFD (Van Cutsem et al., 1998), little is known about the influence of strength training on the physiological and biomechanical benefits derived from the phenomenon. The present research …
Effects Of Long-Term Participation In Tennis On Cognitive Function In Elderly Individuals, Scott Culpin
Effects Of Long-Term Participation In Tennis On Cognitive Function In Elderly Individuals, Scott Culpin
Theses: Doctorates and Masters
Many studies have reported the relationship between exercise and cognition with conflicting results. This may be due to differences in intervention durations, session lengths, intensities, and type of exercise. It has been suggested that exercises requiring greater cognitive demand such as football, basketball and racquet sports, are protective against cognitive decline, compared to less cognitively demanding exercises such as swimming, cycling and running, however, research concerning exercise types are currently limited. The present study tested the hypothesis that elderly individuals who had been regularly playing tennis more than 10 years, would have greater cognitive function than those who had been …
The Influence Of A Simulated Olympic Distance Cycle Exercise On Subsequent Running Economy And Biomechanics In Triathletes, Chantelle Du Plessis
The Influence Of A Simulated Olympic Distance Cycle Exercise On Subsequent Running Economy And Biomechanics In Triathletes, Chantelle Du Plessis
Theses: Doctorates and Masters
The multidisciplinary sport of triathlon provides a good model for testing whether a secondary task can be negatively affected by a preceding task, especially when movement patterns are different. Research suggests that cycling exercise impairs subsequent running performance by altering a runner’s economy and various mechanics (or technique-related) parameters. However, this is not an unambiguous finding. Furthermore, movement patterns are self-optimised during cycling and running to minimise the energy cost, yet the relationship between running mechanics and economy are not clear when different locomotor tasks are performed in succession
Two research studies were conducted with the focus of describing and …
High-Intensity Interval Eccentric Cycling: Acute And Chronic Effects, Marcin Lipski
High-Intensity Interval Eccentric Cycling: Acute And Chronic Effects, Marcin Lipski
Theses: Doctorates and Masters
Eccentric cycling training has been prescribed in continuous and low intensities protocols, based on concentric cycling parameters. While the lower metabolic demand of eccentric than concentric cycling is advantageous for clinical or ‘at-risk’ populations, it is a disadvantage for cardiovascular and pulmonary adaptations. High-intensity interval protocols may increase both, strength and endurance. Thus, this research project compared i) an incremental concentric and eccentric cycling test until exhaustion for the relationship between power output and physiological parameters <Study1>; ii) interval and continuous eccentric cycling protocols for oxygen consumption, perceived exertion and enjoyment <Study 2>; and iii) aerobic performance, muscle …
Does Facial Physiognomy In The Context Of Anoccupational Safety And Health Message Predict Outcomes?, Ian Parker
Does Facial Physiognomy In The Context Of Anoccupational Safety And Health Message Predict Outcomes?, Ian Parker
Theses: Doctorates and Masters
Physiognomy, the practice of looking to another person’s outward facial appearance to unmask the inner character of that person, has had a diverse historical impact within art, medicine, theology, anthropology, law, criminology, political history, psychology, psychiatry, and popular culture, since it was conceptualised in Greece during the 5th and 4th centuries B.C (Physiognomy, 1999-2009, 2009a). Aristotle, the prominent Greek philosopher, penned many chapters on physiognomic properties and touched upon strength/weakness, genius/stupidity, and other trait characteristics and their opposites in so far as such characteristics were associated with facial form (Physiognomy, 2006, 2009b).
In more modern times, facial recognition and evaluation …
Antibiotic Resistance In Gram Negative Bacteria Isolated From Fish Sold In Western Australia, Hannah Kathleen Robinson
Antibiotic Resistance In Gram Negative Bacteria Isolated From Fish Sold In Western Australia, Hannah Kathleen Robinson
Theses: Doctorates and Masters
Background Information The global misuse and overuse of antibiotics in human medicine and the animal production industry is contributing to the development of antibiotic resistance in bacteria. This is a serious threat to modern medicine and public health. Antibiotic resistant organisms can cause severe infections in humans which are difficult to treat, and in some cases impossible to resolve which can lead to premature death. Several studies have been conducted across the globe to assess the use of antibiotics in the seafood industry and the associated health risks, however, limited studies have recently explored this risk in an Australian setting. …
N-Glycosylation Profiles As A Risk Stratification Biomarker For Type Ii Diabetes Mellitus And Its Associated Factors, Eric Adua
Theses: Doctorates and Masters
Worldwide, the prevalence of cardiometabolic diseases, particularly type II diabetes mellitus (T2DM), and to a lesser extent, metabolic syndrome (MetS), has increased dramatically. Despite this increase, there is still a lack of robust biomarkers for cardiometabolic diseases to secure better clinical outcomes. The enzymatic attachment of oligosaccharides (glycans) to proteins-glycosylation is of metabolic and physiological significance, as exploring aberrations of glycosylation profiles can reveal novel biomarkers. In parallel, this process could also explain the biological mechanisms that underpin a suboptimal health status (SHS), a reversible subclinical stage of a cardiometabolic disease. However, studies on the correlation between glycosylation and MetS/T2DM …
“…Like You’Re Pushing The Snowball Back Up Hill”—The Experiences Of Australian Physiotherapists Promoting Non-Treatment Physical Activity: A Qualitative Study, Breanne E. Kunstler, Paul D. O'Halloran, Jill L. Cook, Joanne L. Kemp, Caroline Finch
“…Like You’Re Pushing The Snowball Back Up Hill”—The Experiences Of Australian Physiotherapists Promoting Non-Treatment Physical Activity: A Qualitative Study, Breanne E. Kunstler, Paul D. O'Halloran, Jill L. Cook, Joanne L. Kemp, Caroline Finch
Research outputs 2014 to 2021
Participating in physical activity is important for maintaining general health. When physiotherapists promote physical activity for the purposes of maintaining or improving a patient‟s general health, they are promoting non-treatment physical activity. Physiotherapists have a responsibility to promote non-treatment physical activity to their patients while also providing the patient with treatment for their presenting complaint. This qualitative study explored the experiences of Australian physiotherapists promoting non-treatment physical activity to patients with musculoskeletal conditions. Ten Australian physiotherapists treating patients with musculoskeletal conditions in private practice and outpatient settings were recruited using a social media campaign and snowballing. All interviewees received one …
Web-Delivered Cognitive Behavioral Therapy For Distressed Cancer Patients: Randomized Controlled Trial, Suzanne K. Chambers, Lee M. Ritterband, Frances Thorndike, Lisa Nielsen, Joanne F. Aitken, Samantha Clutton, Paul A. Scuffham, Philippa Youl, Bronwyn Morris, Peter D. Baade, Jeff Dunn
Web-Delivered Cognitive Behavioral Therapy For Distressed Cancer Patients: Randomized Controlled Trial, Suzanne K. Chambers, Lee M. Ritterband, Frances Thorndike, Lisa Nielsen, Joanne F. Aitken, Samantha Clutton, Paul A. Scuffham, Philippa Youl, Bronwyn Morris, Peter D. Baade, Jeff Dunn
Research outputs 2014 to 2021
Background: Web-based interventions present a potentially cost-effective approach to supporting self-management for cancer patients; however, further evidence for acceptability and effectiveness is needed.
Objective: The goal of our research was to assess the effectiveness of an individualized Web-based cognitive behavioral therapy (CBT) intervention on improving psychological and quality of life outcomes in cancer patients with elevated psychological distress.
Methods: A total of 163 distressed cancer patients (111 female, 68.1%) were recruited through the Queensland Cancer Registry and the Cancer Council Queensland Cancer Helpline and randomly assigned to either a Web-based tailored CBT intervention (CancerCope) (79/163) or a static …
Selective Influences Of Maximum Dynamic Strength And Bar-Power Output On Team Sports Performance: A Comprehensive Study Of Four Different Disciplines, Irineu Loturco, Timothy Suchome, Lachlan P. James, Chris Bishop, César C. C. Abad, Lucas A. Pereira, Michael R. Mcguigan
Selective Influences Of Maximum Dynamic Strength And Bar-Power Output On Team Sports Performance: A Comprehensive Study Of Four Different Disciplines, Irineu Loturco, Timothy Suchome, Lachlan P. James, Chris Bishop, César C. C. Abad, Lucas A. Pereira, Michael R. Mcguigan
Research outputs 2014 to 2021
This study examined the selective influences of one-repetition maximum (1RM) values [assessed in the half-squat (HS)] and bar-power production [assessed in both HS and jump squat (JS) exercises] on the physical performance of male and female team sport athletes from four different sports. Three-hundred and three elite players (31 Olympians) from four different disciplines (47 male soccer players, 58 female soccer players, 28 male handball players, 58 female handball players, 49 male rugby players, and 63 male futsal players) participated in this study. The physical tests were performed over 2 consecutive days for soccer and rugby players, and in 1 …
Efficacy Of The Aussie Optimism Program: Promoting Pro-Social Behavior And Preventing Suicidality In Primary School Students. A Randomised-Controlled Trial, Clare M. Roberts, Robert T. Kane, Rosanna M. Rooney, Yolanda Pintabona, Natalie Baughman, Sharinaz Hassan, Donna Cross, Stephen R. Zubrick, Sven R. Silburn
Efficacy Of The Aussie Optimism Program: Promoting Pro-Social Behavior And Preventing Suicidality In Primary School Students. A Randomised-Controlled Trial, Clare M. Roberts, Robert T. Kane, Rosanna M. Rooney, Yolanda Pintabona, Natalie Baughman, Sharinaz Hassan, Donna Cross, Stephen R. Zubrick, Sven R. Silburn
Research outputs 2014 to 2021
The efficacy of an enhanced version of the Aussie Optimism Program (AOP) was investigated in a cluster randomized controlled trial. Grade 6 students aged 10–11 years of age (N = 2288) from 63 government primary schools in Perth, Western Australia, participated in the pre, post, and follow-up study. Schools were randomly assigned to one of three conditions: Aussie Optimism with teacher training, Aussie Optimism with teacher training plus coaching, or a usual care condition that received the regular Western Australian Health Education Curriculum. Students in the Aussie Optimism conditions received 20, 1-h lessons relating to social and interpersonal skills and …
Profiling Shoulder Strength In Competitive Surfers, James Furness, Ben Schram, Tim Cottman-Fields, Brendan Solia, Josh Secomb
Profiling Shoulder Strength In Competitive Surfers, James Furness, Ben Schram, Tim Cottman-Fields, Brendan Solia, Josh Secomb
Research outputs 2014 to 2021
The shoulder region has the highest incidence of acute injuries in the sport of surfing. Little is known about the strength profile at the shoulder in a surfing cohort. The primary aim of this study was to establish the reliability of a rotator cuff strength testing procedure for surfers with a secondary aim of providing a profile of internal and external rotation strength in a competitive surfing cohort. Shoulder internal rotation and external rotation isometric strength was measured using a hand-held dynamometer in 13 competitive surfers. Intra-class coefficient values ranged from 0.97 to 0.98 for intra-rater reliability and were lower …
Prescribing Target Running Intensities For High-School Athletes: Can Forward And Backward Running Performance Be Autoregulated?, Aaron Uthoff, Jon Oliver, John Cronin, Paul Winwood, Craig Harrison
Prescribing Target Running Intensities For High-School Athletes: Can Forward And Backward Running Performance Be Autoregulated?, Aaron Uthoff, Jon Oliver, John Cronin, Paul Winwood, Craig Harrison
Research outputs 2014 to 2021
Target running intensities are prescribed to enhance sprint-running performance and progress injured athletes back into competition, yet is unknown whether running speed can be achieved using autoregulation. This study investigated the consistency of running intensities in adolescent athletes using autoregulation to self-select velocity. Thirty-four boys performed 20 m forward running (FR) and backward running (BR) trials at slow, moderate and fast intensities (40–55%, 60–75% and +90% maximum effort, respectively) on three occasions. Absolute and relative consistency was assessed using the coefficient of variation (CV) and intraclass correlation coefficients (ICC). Systematic changes in 10 and 20 m performance were identified between …
Effect Of Plyometric Training On Speed And Change Of Direction Ability In Elite Field Hockey Players, Jasdev Singh, Brendyn B. Appleby, Andrew P. Lavender
Effect Of Plyometric Training On Speed And Change Of Direction Ability In Elite Field Hockey Players, Jasdev Singh, Brendyn B. Appleby, Andrew P. Lavender
Research outputs 2014 to 2021
This study investigated the effects of two plyometric training protocols on sprint and change of direction (COD) performance in elite hockey players. A parallel-group randomized controlled trial design was used and seventeen elite male and female field hockey players were randomly allocated into either low-to-high (L-H, n = 8) or high-to-low (H-L, n = 9) training groups. Each group performed separate variations of the drop jump exercise twice weekly for six weeks, with an emphasis on either jump height (L-H) or drop height (H-L). Performance variables assessed included sprint times over 10 m and 20 m, as well as 505 …
Feasibility And Preliminary Efficacy Of A 10-Week Resistance And Aerobic Exercise Intervention During Neoadjuvant Chemoradiation Treatment In Rectal Cancer Patients, Favil Singh, Daniel A. Galvão, Robert Newton, Nigel A. Spry, Michael K. Baker, Dennis Taaffe
Feasibility And Preliminary Efficacy Of A 10-Week Resistance And Aerobic Exercise Intervention During Neoadjuvant Chemoradiation Treatment In Rectal Cancer Patients, Favil Singh, Daniel A. Galvão, Robert Newton, Nigel A. Spry, Michael K. Baker, Dennis Taaffe
Research outputs 2014 to 2021
Background:
Neoadjuvant chemoradiation treatment (CRT) in rectal cancer patients is associated with a reduction in physical capacity, lean mass and increased fatigue. As a countermeasure to these treatment-related adverse effects, we examined the feasibility and preliminary efficacy of a 10-week exercise program during CRT.
Methods:
Ten rectal cancer patients (7 men, aged 27-70 years, body mass index = 26.4 ± 3.8 kg/m2) receiving CRT undertook supervised resistance and aerobic exercise twice weekly. Assessments were undertaken pre- and post-intervention for upper and lower body muscle strength by 1-RM, muscle endurance, physical performance tests, body composition by dual X-ray absorptiometry, quality of …
Changes In Knowledge And Attitudes Of Hospital Environmental Services Staff: The Researching Effective Approaches To Cleaning In Hospitals (Reach) Study, Brett Mitchell, Nicole White, Alison Farrington, Michelle Allen, Katie Page, Anne Gardner, Kate Halton, Thomas Riley, Christian Gericke, David Paterson, Nicholas Graves, Lisa Hall
Changes In Knowledge And Attitudes Of Hospital Environmental Services Staff: The Researching Effective Approaches To Cleaning In Hospitals (Reach) Study, Brett Mitchell, Nicole White, Alison Farrington, Michelle Allen, Katie Page, Anne Gardner, Kate Halton, Thomas Riley, Christian Gericke, David Paterson, Nicholas Graves, Lisa Hall
Research outputs 2014 to 2021
Background
The Researching Effective Approaches to Cleaning in Hospitals (REACH) study tested a multimodal cleaning intervention in Australian hospitals. This article reports findings from a pre/post questionnaire, embedded into the REACH study, that was administered prior to the implementation of the intervention and at the conclusion of the study.
Methods
A cross-sectional questionnaire, nested within a stepped-wedge trial, was administered. The REACH intervention was a cleaning bundle comprising 5 interdependent components. The questionnaire explored the knowledge, reported practice, attitudes, roles, and perceived organizational support of environmental services staff members in the hospitals participating in the REACH study.
Results
Environmental services …
Uv Light-Blocking Contact Lenses Protect Against Short-Term Uvb-Induced Limbal Stem Cell Niche Damage And Inflammation, M. Notara, S. Behboudifard, M. A. Kluth, C. Maßlo, C. Ganss, M. H. Frank, B. Schumacher, C. Cursiefen
Uv Light-Blocking Contact Lenses Protect Against Short-Term Uvb-Induced Limbal Stem Cell Niche Damage And Inflammation, M. Notara, S. Behboudifard, M. A. Kluth, C. Maßlo, C. Ganss, M. H. Frank, B. Schumacher, C. Cursiefen
Research outputs 2014 to 2021
UVB irradiation has been linked to pathogenesis of pterygium, a conjunctival tumor growing onto transparent cornea, the windscreen of the eye. Due to corneal anatomy, ambient UVB irradiation is amplified at the stem cell-containing nasal limbus. The aim of this study was to analyse the effect of a UV-blocking contact lens (UVBCL, senofilcon A, Class 1 UV blocker) on limbal epithelial cells and fibroblasts under UVB irradiation compared to a non-UVB-blocking contact lens. UVBCL prevented UVB-induced DNA damage (as assessed by cyclobutane pyrimidine dimer immunostaining) as well as a decrease in proliferation and scratch wound closure rate of both limbal …
Seed Coats Of Pulses As A Food Ingredient: Characterization, Processing, And Applications, Liezhou Zhong, Zhongxiang Fang, Mark L. Wahlqvist, Gangcheng Wu, Jonathan M. Hodgson, Stuart K. Johnson
Seed Coats Of Pulses As A Food Ingredient: Characterization, Processing, And Applications, Liezhou Zhong, Zhongxiang Fang, Mark L. Wahlqvist, Gangcheng Wu, Jonathan M. Hodgson, Stuart K. Johnson
Research outputs 2014 to 2021
Background In recognition of their multiple benefits on environment, food security, and human health, pulses are attracting worldwide attention. The seed coat is a major by-product of pulse processing, and its only markets are as low value ruminant feed and very limited use in high fibre foods. Recently, accumulating studies have suggested that this underutilised by-product has greater potential as a novel natural “nutritious dietary fibre” which can be used as a functional food ingredient.
Scope and approach This review discusses biochemical and physicochemical functionalities of seed coats of six globally important pulses: chickpea, field pea, faba/broad bean, lentil and …
Whole Body Vibration Exposure On Markers Of Bone Turnover, Body Composition, And Physical Functioning In Breast Cancer Patients Receiving Aromatase Inhibitor Therapy: A Randomized Controlled Trial, Michael K. Baker, Carolyn J. Mcintyre, Daniel A. Galvão, Catherine Hunt, Nigel Spry, Robert Newton
Whole Body Vibration Exposure On Markers Of Bone Turnover, Body Composition, And Physical Functioning In Breast Cancer Patients Receiving Aromatase Inhibitor Therapy: A Randomized Controlled Trial, Michael K. Baker, Carolyn J. Mcintyre, Daniel A. Galvão, Catherine Hunt, Nigel Spry, Robert Newton
Research outputs 2014 to 2021
Introduction: Women with breast cancer are often prescribed aromatase inhibitors, which can cause rapid loss of bone mass leading to significant potential for morbidity. Vibration training has been shown to be helpful in reducing bone turnover in postmenopausal women without cancer.
Aim: To examine the effect of vibration stimulus on markers of bone turnover in breast cancer patients receiving aromatase inhibitors.
Methods: Thirty-one breast cancer survivors undergoing treatment with aromatase inhibitors were randomized to vibration stimulus (n = 14) or usual care control (n = 17). Low-frequency and low-magnitude vibration stimulus (27-32 Hz, 0.3g) was delivered in supervised …
Geographic Disparities In Previously Diagnosed Health Conditions In Colorectal Cancer Patients Are Largely Explained By Age And Area Level Disadvantage, Belinda C Goodwin, Sonja March, Michael J Ireland, Fiona Crawford-Williams, Shu-Kay Ng, Peter D Baade, Suzanne K. Chambers, Joanne F Aitken, Jeff Dunn
Geographic Disparities In Previously Diagnosed Health Conditions In Colorectal Cancer Patients Are Largely Explained By Age And Area Level Disadvantage, Belinda C Goodwin, Sonja March, Michael J Ireland, Fiona Crawford-Williams, Shu-Kay Ng, Peter D Baade, Suzanne K. Chambers, Joanne F Aitken, Jeff Dunn
Research outputs 2014 to 2021
Background: Geographical disparity in colorectal cancer (CRC) survival rates may be partly due to aging populations and disadvantage in more remote locations; factors that also impact the incidence and outcomes of other chronic health conditions. The current study investigates whether geographic disparity exists amongst previously diagnosed health conditions in CRC patients above and beyond age and area-level disadvantage and whether this disparity is linked to geographic disparity in CRC survival.
Methods: Data regarding previously diagnosed health conditions were collected via computer-assisted telephone interviews with a cross-sectional sample of n = 1,966 Australian CRC patients between 2003 and 2004. Ten-year survival …
The Changes Of Immunoglobulin G N-Glycosylation In Blood Lipids And Dyslipidaemia, Di Liu, Xi Chu, Hao Wang, Jing Dong, Si-Qi Ge, Zhong-Yao Zhao, Hong-Li Peng, Ming Sun, Li-Juan Wu, Man-Shu Song, Xiu-Hua Guo, Qun Meng, You-Xin Wang, Gordan Lauc, Wei Wang
The Changes Of Immunoglobulin G N-Glycosylation In Blood Lipids And Dyslipidaemia, Di Liu, Xi Chu, Hao Wang, Jing Dong, Si-Qi Ge, Zhong-Yao Zhao, Hong-Li Peng, Ming Sun, Li-Juan Wu, Man-Shu Song, Xiu-Hua Guo, Qun Meng, You-Xin Wang, Gordan Lauc, Wei Wang
Research outputs 2014 to 2021
Background
Alternative N-glycosylation has significant structural and functional consequences on immunoglobulin G (IgG) and can affect immune responses, acting as a switch between pro- and anti-inflammatory IgG functionality. Studies have demonstrated that IgG N-glycosylation is associated with ageing, body mass index, type 2 diabetes and hypertension.
Methods
Herein, we have demonstrated patterns of IgG glycosylation that are associated with blood lipids in a cross-sectional study including 598 Han Chinese aged 20–68 years. The IgG glycome composition was analysed by ultra-performance liquid chromatography.
Results
Blood lipids were positively correlated with glycan peak GP6, whereas they were negatively correlated with …
Predictors Of Noncompliance To Antihypertensive Therapy Among Hypertensive Patients Ghana: Application Of Health Belief Model, Yaa Obirikorang, Christian Obirikorang, Emmanuel Acheampong, Enoch Odame Anto, Daniel Gyamfi, Selorm Philip Segbefia, Michael Opoku Boateng, Dari Pascal Dapilla, Peter Kojo Brenya, Bright Amankwaa, Evans Asamoah Adu, Emmanuel Nsenbah Batu, Adjei Gyimah Akwasi, Beatrice Amoah
Predictors Of Noncompliance To Antihypertensive Therapy Among Hypertensive Patients Ghana: Application Of Health Belief Model, Yaa Obirikorang, Christian Obirikorang, Emmanuel Acheampong, Enoch Odame Anto, Daniel Gyamfi, Selorm Philip Segbefia, Michael Opoku Boateng, Dari Pascal Dapilla, Peter Kojo Brenya, Bright Amankwaa, Evans Asamoah Adu, Emmanuel Nsenbah Batu, Adjei Gyimah Akwasi, Beatrice Amoah
Research outputs 2014 to 2021
This study determined noncompliance to antihypertensive therapy (AHT) and its associated factors in a Ghanaian population by using the health belief model (HBM). This descriptive cross-sectional study conducted at Kintampo Municipality in Ghana recruited a total of 678 hypertensive patients. The questionnaire constituted information regarding sociodemographics, a five-Likert type HBM questionnaire, and lifestyle-related factors. The rate of noncompliance to AHT in this study was 58.6%. The mean age (SD) of the participants was 43.5 (±5.2) years and median duration of hypertension was 2 years. Overall, the five HBM constructs explained 31.7% of the variance in noncompliance to AHT with a …
Evaluation Of Individual And Combined Markers Of Urine Dipstick Parameters And Total Lymphocyte Count As A Substitute For Cd4 Count In Low-Resource Communities In Ghana, Enoch Odame Anto, Christian Obirikorang, Emmanuel Acheampong, Bright Amankwaa, Bright Oppong Afranie, Sampson Donkor, Isaac Hope, Juliana Jommo, Esther Osaah
Evaluation Of Individual And Combined Markers Of Urine Dipstick Parameters And Total Lymphocyte Count As A Substitute For Cd4 Count In Low-Resource Communities In Ghana, Enoch Odame Anto, Christian Obirikorang, Emmanuel Acheampong, Bright Amankwaa, Bright Oppong Afranie, Sampson Donkor, Isaac Hope, Juliana Jommo, Esther Osaah
Research outputs 2014 to 2021
We evaluated the individual and combined levels of urine dipstick and total lymphocyte count (TLC) as surrogate markers for CD4 count in a low-resource community in Ghana. This cross-sectional study recruited 200 HIV-infected patients from the Saint Francis Xavier Hospital, Assin Fosu, Ghana. Complete blood count, CD4 count, and urine dipstick analysis were measured for participants. The threshold values were determined as/
Caffeine With Links To Nafld And Accelerated Brain Aging, Ian James Martins
Caffeine With Links To Nafld And Accelerated Brain Aging, Ian James Martins
Research outputs 2014 to 2021
Nutritional diets are essential to prevent nonalcoholic fatty liver disease (NAFLD) in the global obesity and diabetes epidemic. The ingestion of palmitic acid-rich diets induces NAFLD in animal and human studies. The beneficial properties of olive oil (oleic acid) may be superseded by ingestion of palmitic acid-rich diets. Hepatic caffeine metabolism is regulated by palmitic and oleic acid with effects of these fats on amyloid beta metabolism. Healthy fats such as olive oil may facilitate rapid amyloid beta clearance in the periphery to maintain drug therapy in diabetes and various neurological diseases. Repression of the anti-aging gene sirtuin 1 (Sirt …
Socio-Economic Predictors And Distribution Of Tuberculosis Incidence In Beijing, China: A Studyusing A Combination Of Spatial Statistics And Gis Technology, Gehendra Mahara, Kun Yang, Sipeng Chen, Wei Wang, Xiuhua Guo
Socio-Economic Predictors And Distribution Of Tuberculosis Incidence In Beijing, China: A Studyusing A Combination Of Spatial Statistics And Gis Technology, Gehendra Mahara, Kun Yang, Sipeng Chen, Wei Wang, Xiuhua Guo
Research outputs 2014 to 2021
Evidence shows that multiple factors, such as socio-economic status and access to health care facilities, affect tuberculosis (TB) incidence. However, there is limited literature available with respect to the correlation between socio-economic/health facility factors and tuberculosis incidence. This study aimed to explore the relationship between TB incidence and socio-economic/health service predictors in the study settings. A retrospective spatial regression analysis was carried out based on new sputum smear-positive pulmonary TB cases in Beijing districts. Global Moran’s I analysis was adopted to detect the spatial dependency followed by spatial regression models (spatial lag model, and spatial error model) along with the …
Wnt/B-Catenin Signalling During Liver Metabolism, Chronic Liver Disease And Hepatocarcinogenesis, Gayatri D. Shirolkar, Sara Pasic, Jully Gogoi-Tiwari, Manoj K. Bhat, John K. Olynyk, Dharmarajan Dharmarajan, Janina E.E. Tirnitz-Parker
Wnt/B-Catenin Signalling During Liver Metabolism, Chronic Liver Disease And Hepatocarcinogenesis, Gayatri D. Shirolkar, Sara Pasic, Jully Gogoi-Tiwari, Manoj K. Bhat, John K. Olynyk, Dharmarajan Dharmarajan, Janina E.E. Tirnitz-Parker
Research outputs 2014 to 2021
Chronic liver diseases (CLDs) are increasing in prevalence and their end-stage complications, namely, cirrhosis, liver failure and hepatocellular carcinoma represent major global challenges. The most common initiators of progressive CLD are viral hepatitis and long-term alcohol abuse as well as steatosis and steatohepatitis. Irrespective of the underlying aetiology, a common feature of CLD is the formation of hepatic ductular reactions, involving the proliferation of liver progenitor cells (LPCs) and their signalling to fibrosis-driving hepatic stellate cells. The Wnt/β-catenin pathway has been found to regulate development, stemness and differentiation, and alterations in its activity have been associated with tumour development. Recent …
Hepatic Iron Concentration Correlates With Insulin Sensitivity In Non-Alcoholic Fatty Liver Disease, Laurence Britton, Kim Bridle, Janske Reiling, Nishreen Santrampurwala, Leesa Wockner, Helena Ching, Katherine Stuart, V. Nathan Subramaniam, Gary Jeffrey, Tim St. Pierre, Michael House, Joel Gummer, Robert Trengove, John K. Olynyk, Darrell Crawford, Leon Adams
Hepatic Iron Concentration Correlates With Insulin Sensitivity In Non-Alcoholic Fatty Liver Disease, Laurence Britton, Kim Bridle, Janske Reiling, Nishreen Santrampurwala, Leesa Wockner, Helena Ching, Katherine Stuart, V. Nathan Subramaniam, Gary Jeffrey, Tim St. Pierre, Michael House, Joel Gummer, Robert Trengove, John K. Olynyk, Darrell Crawford, Leon Adams
Research outputs 2014 to 2021
Rodent and cell‐culture models support a role for iron‐related adipokine dysregulation and insulin resistance in the pathogenesis of nonalcoholic fatty liver disease (NAFLD); however, substantial human data are lacking. We examined the relationship between measures of iron status, adipokines, and insulin resistance in patients with NAFLD in the presence and absence of venesection. This study forms part of the Impact of Iron on Insulin Resistance and Liver Histology in Nonalcoholic Steatohepatitis (IIRON2) study, a prospective randomized controlled trial of venesection for adults with NAFLD. Paired serum samples at baseline and 6 months (end of treatment) in controls (n = 28) …
A Comparison Of Displacement And Energetic Variables Between Three Team Sport Gps Devices, Paolo Terziotti, Marc Sim, Ted Polglaze
A Comparison Of Displacement And Energetic Variables Between Three Team Sport Gps Devices, Paolo Terziotti, Marc Sim, Ted Polglaze
Research outputs 2014 to 2021
This study compared the outputs of three different commercially-available GPS player-tracking devices for a range of commonly used displacement and energetic variables in activities replicating team sport movements. Professional male soccer players (n = 7), simultaneously wore three GPS devices (Catapult OptimEye S5, GPExe Pro 1, StatSport ViperPod) whilst completing four separate drills, comprising progressively more complex changes in speed and direction. Displacement (distance, speed) and energetic (energy cost, metabolic power, energy expenditure) variables were compared for each device. All three devices tended to under-estimate distance compared to the known value for each drill, with only minor and inconsistent …
Attitudes Of Doctors And Nurses Toward Patient Safety Within Emergency Departments Of Two Saudi Arabian Hospitals, Naif Alzahrani, Russell Jones, Mohamed E. Abdel-Latif
Attitudes Of Doctors And Nurses Toward Patient Safety Within Emergency Departments Of Two Saudi Arabian Hospitals, Naif Alzahrani, Russell Jones, Mohamed E. Abdel-Latif
Research outputs 2014 to 2021
Background: A hospital culture that promotes and insures patient safety is a critical aspect for the effective delivery of hospital services and patient care. Yet there are significant patient health and safety issues in hospitals worldwide. This study aims to investigate doctors’ and nurses’ attitudes toward patient safety in the emergency departments (ED) of two Saudi hospitals.
Method: A cross-sectional survey using a validated Safety Attitudes Questionnaire (SAQ) was used. Total of 503 ED doctors and nurses completed SAQ. Correlation analysis, using Spearman’s Rho, was performed between the number of incidents reported and each dimension of the SAQ. …