Medicine and Health Sciences Commons^™

Contralateral Versus Ipsilateral Protective Effect Against Muscle Damage Of The Elbow Flexors And Knee Extensors Induced By Maximal Eccentric Exercise, Trevor C. Chen, Hsin Lian Chen, Wei Chin Tseng, Tai Ying Chou, Jui Hung Tu, Allen C. Parcell, Kazunori Nosaka

Research outputs 2022 to 2026

The present study compared the ipsilateral repeated bout effect (IL-RBE) and contralateral repeated bout effect (CL-RBE) of the elbow flexors (EF) and knee flexors (KF) for the same interval between bouts to shed light on their mechanisms. Fifty-two healthy sedentary young (20–28 years) men were randomly assigned to the IL-EF, IL-KF, CL-EF, and CL-KF groups (n = 13/group). Thirty maximal eccentric contractions of the EF were performed in IL-EF and CL-EF, and 60 maximal eccentric contractions of the KF were performed in IL-KF and CL-KF, with a 2-week interval between bouts. Changes in muscle damage markers such as maximal voluntary …

Increases In Integrin-Ilk-Rictor-Akt Proteins, Muscle Mass, And Strength After Eccentric Cycling Training, Georgios Mavropalias, Yu-Fu Wu, Marni D. Boppart, Anthony J. Blazevich, Kazunori Nosaka

Research outputs 2022 to 2026

PURPOSE:

Recently, it has been suggested that a cellular pathway composed of integrin, integrin-linked kinase (ILK), rapamycin-insensitive companion of mTOR (RICTOR), and Akt may facilitate long-term structural and functional adaptations associated with exercise, independent of the mTORC1 pathway. Therefore, we examined changes in integrin-ILK-RICTOR-Akt protein in vastus lateralis (VL) before and after 8 wk of eccentric cycling training (ECC), which was expected to increase muscle function and VL cross-sectional area (CSA).

METHODS:

Eleven men (23 ± 4 yr) completed 24 sessions of ECC with progressive increases in intensity and duration, resulting in a twofold increase in work from the first …

Changes In Plasma Hydroxyproline And Plasma Cell-Free Dna Concentrations After Higher- Versus Lower-Intensity Eccentric Cycling, Georgios Mavropalias, Leslie Calapre, Michael Morici, Tomoko Koeda, Wayne C. K. Poon, Oliver R. Barley, Elin Gray, Anthony J. Blazevich, Kazunori Nosaka

Research outputs 2014 to 2021

Purpose:

We examined changes in plasma creatine kinase (CK) activity, hydroxyproline and cell-free DNA (cfDNA) concentrations in relation to changes in maximum voluntary isometric contraction (MVIC) torque and delayed-onset muscle soreness (DOMS) following a session of volume-matched higher- (HI) versus lower-intensity (LI) eccentric cycling exercise.

Methods:

Healthy young men performed either 5 × 1-min HI at 20% of peak power output (n = 11) or 5 × 4-min LI eccentric cycling at 5% of peak power output (n = 9). Changes in knee extensor MVIC torque, DOMS, plasma CK activity, and hydroxyproline and cfDNA concentrations before, immediately after, and 24–72 …

High-Intensity Interval Eccentric Cycling: Acute And Chronic Effects, Marcin Lipski

Theses: Doctorates and Masters

Eccentric cycling training has been prescribed in continuous and low intensities protocols, based on concentric cycling parameters. While the lower metabolic demand of eccentric than concentric cycling is advantageous for clinical or ‘at-risk’ populations, it is a disadvantage for cardiovascular and pulmonary adaptations. High-intensity interval protocols may increase both, strength and endurance. Thus, this research project compared i) an incremental concentric and eccentric cycling test until exhaustion for the relationship between power output and physiological parameters <Study1>; ii) interval and continuous eccentric cycling protocols for oxygen consumption, perceived exertion and enjoyment <Study 2>; and iii) aerobic performance, muscle …

Eccentric Loading Increases Peak Torque Angle Of The Ankle Plantar Flexors In Healthy Volunteers, Matthew Wellisch, Peter Hamer, Luke Hopper, Max Bulsara, James Debenham

Research outputs 2014 to 2021

Eccentric loading of the ankle plantar Flexor's (PF) has demonstrated clinical efficacy in the conservative treatment of Achilles tendinopathy, however, its mechanism of therapeutic benefit remains unclear. The purpose of this study was to examine the effects of PF eccentric loading on PF angle to peak torque (AtPT), peak torque (PT) and lower limb vertical stiffness. Thirty healthy volunteers were randomised to an eccentric (n=15) or concentric (n=13) exercise group. A 10-week loading programme of the ankle plantar flexors was completed. AtPT, PT and vertical stiffness were compared within and between groups before and after the interventions. AtPT increased in …

Pain Assessment And Possible Mechanism Of Delayed Onset Muscle Soreness, Wing Yin Lau

Theses: Doctorates and Masters

Muscle pain is felt during exercise or daily activities for several days after performing unaccustomed exercise, which is referred to as delayed onset muscle soreness (DOMS). Many people experience DOMS, but its underlying mechanisms are not fully understood. One of the challenges in the investigation of DOMS is its subjective nature, which makes the assessment ambiguous, thus establishing a standardised protocol is necessary. The present thesis scrutinised muscle pain assessments (Study 1, Study 2), developed a new assessment of muscle pain focusing on muscle fascia (Study 3), and investigated why DOMS is reduced after the second than the first bout …

Visual Analog Scale And Pressure Pain Threshold For Delayed Onset Muscle Soreness Assessment, Wing Y. Lau, Makii Mishan Muthalib, Kazunori Nosaka

Research outputs 2013

Objectives: To investigate the relationship between two assessments to quantify delayed onset muscle soreness [DOMS]: visual analog scale [VAS] and pressure pain threshold [PPT]. Methods: Thirty-one healthy young men [25.8±5.5 years] performed 10 sets of six maximal eccentric contractions of the elbow flexors with their non-dominant arm. Before and one to four days after the exercise, muscle pain perceived upon palpation of the biceps brachii at three sites [5, 9 and 13cm above the elbow crease] was assessed by VAS with a 100mm line [0=no pain, 100=extremely painful], and PPT of the same sites was determined by an algometer. Changes …

Changes In Power Assessed By The Wingate Anaerobic Test Following Downhill Running, Carmel Nottle, Kazunori Nosaka

Research outputs pre 2011

No abstract provided.

An Investigation Of The Effect Of Exercised Arm, Training Status, And Racial Background On Changes In Markers Of Muscle Damage Following Maximal Eccentric Exercise Of The Elbow Flexors, Michael J. Newton

Theses: Doctorates and Masters

Despite the substantial body of research accumulated on exercise-induced muscle damage, there remain several areas that warrant further investigation. Study groups comprised of individuals from differing racial background and /or training status have the potential to influence the intra-group variability in damage markers following eccentric exercise. In addition, if a contralateral arm model is employed, intra- and inter-group variation could be influenced by the formation of groups based on limb dominance and /or the order in which the arms are exercised. Currently there is a dearth of research addressing these factors, however, these types of studies are important as they …