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Expression Of Prostaglandin F2 Alpha Receptors (Ptgfr) And C-Reactive Protein (Crp) In The Canine Uterus And Cervix With Opened- And Closed-Cervix Pyometra, Narong Tiptanavattana, Pokchon Khirilak, Theerawat Tharasanit, Natapol Duangtum, Kijsopon Jankaew, Prawit Sae-Jia, Nongnapat Kaewchana
Expression Of Prostaglandin F2 Alpha Receptors (Ptgfr) And C-Reactive Protein (Crp) In The Canine Uterus And Cervix With Opened- And Closed-Cervix Pyometra, Narong Tiptanavattana, Pokchon Khirilak, Theerawat Tharasanit, Natapol Duangtum, Kijsopon Jankaew, Prawit Sae-Jia, Nongnapat Kaewchana
The Thai Journal of Veterinary Medicine
Pyometra is a common reproductive disorder in female dogs. This study investigated the protein expression of prostaglandin F2 alpha receptors (PTGFR) and C-reactive protein (CRP) in responses to inflammatory events of uterine and cervical tissues in dogs. Uterus and cervix samples were collected from six dogs which had closed-cervix pyometra (n = 3) and opened- cervix pyometra (n = 3). Healthy dogs in diestrus (n = 3) and anestrus (n=3) were used as controls. Tissues were histologically prepared and stained with hematoxylin and eosin. Immunohistochemistry (IHC) and western blot analysis for the PTGFR and CRP were used to verify the …