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Full-Text Articles in Medicine and Health Sciences
Preliminary Study Of The Clinical Outcome Of Using Pcso-524 Polyunsaturated Fatty Acid Compound In The Treatment Of Canine Osteoarthritis And Degenerative Spinal Diseases, Natwadee Mongkon, Kumpanart Soontornvipart
Preliminary Study Of The Clinical Outcome Of Using Pcso-524 Polyunsaturated Fatty Acid Compound In The Treatment Of Canine Osteoarthritis And Degenerative Spinal Diseases, Natwadee Mongkon, Kumpanart Soontornvipart
The Thai Journal of Veterinary Medicine
The clinical outcome of PCSO-524 application in the treatment of canine osteoarthritis and spinal disorderwas studied at the Small Animal Teaching Hospital, Chulalongkorn University. Eighty-four dogs were included inour study. Thirty-one dogs showed signs of osteoarthritis (OA) in both hip joints and shoulder joints; 33 dogs had OAin stifle joints from cranial cruciate ligament rupture; and 20 dogs had neurological signs of the cauda equinasyndrome. All affected dogs were treated by 50 mg/ 10 kg of PCSO-524, PO for twelve weeks. Neurological grading,lameness scores and neurological examinations were evaluated before and after the administration of PCSO-524 fortwo and four weeks. …
Role Of Matrix Metalloproteinases In Animals, Sariya Asawakarn, Tanong Asawakarn
Role Of Matrix Metalloproteinases In Animals, Sariya Asawakarn, Tanong Asawakarn
The Thai Journal of Veterinary Medicine
Matrix metalloproteinases are a family of calcium-dependent and zinc-dependent endopeptidases, which excrete from many cell types. These enzymes can hydrolyze extracellular matrix proteins. The most important inhibitor of MMPs is tissue inhibitors of metalloproteinases (TIMPs). The imbalance between MMPs and TIMPs causes pathological condition in human and animals. This review focuses on structural, role and several reports of MMPs in horse, dog, cat, fish and avian. Over production of MMPs is associated with tissue destruction and erosion of cartilage in equine osteoarthritis, especially MMP-2 and MMP-9. In canine and feline, many evidences reported about MMPs and cancer such as MMP-2 …
Efficacy And Safety Of Prosulf-Forte In The Treatment Of Osteoarthritis Of The Knee At King Chulalongkorn Memorial Hospital, P Kitidumrongsook, P Luengjamikorn, Y Wangroongsub, P. Tienboon
Efficacy And Safety Of Prosulf-Forte In The Treatment Of Osteoarthritis Of The Knee At King Chulalongkorn Memorial Hospital, P Kitidumrongsook, P Luengjamikorn, Y Wangroongsub, P. Tienboon
Chulalongkorn Medical Journal
Background : Glucosamine has long been used for the treatment of osteoarthritis because of its safety. Efficacy of each product may vary from their crystallinity and salt composition. Increase of blood glucose may occurred from high dose preparation. Objective : To test the efficacy and safety of glucosamine sulfate 500 mg capsule (Prosulf-Forte, Aerocare) in mild to moderate degree of knee osteoarthritis. Design : Double-blind cross- over design study. Setting : Department of Orthopaedic Surgery, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital Material and Methods : The trial recruited two groups of patients with knee osteoarthritis of …