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Prevalence And Mortality Rate Of Severe Cutaneous Adverse Reactions At Siriraj Hospital, S Limkobpaiboon, D. Panomvanna Na Ayudhya, N Dhana, K. Jongjarearnprasert

Chulalongkorn Medical Journal

Introduction : Stevens-Johnson syndrome (SJS), Toxic Epidermal Necrolysis (TEN) and drug hypersensitivity syndrome (HSS) are severe cutaneous adverse reactions (SCAR) that is mostly related to drugs. Although incidence is rare, it has significant impact on patient's well being because of its high mortality rates. Objective : To investigate the causative drugs, prevalence and mortality rates related to SCAR, which were from drug exposure during 2003 - 2007. Setting : Siriraj Hospital, Bangkok. Research design : A retrospective study Patients : Patients who were diagnosed to be SJS, TEN and HSS were included. Method : Five years retrospective data, 2003 - …