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Full-Text Articles in Medicine and Health Sciences
Determining The Correlation Between Hemoglobin Levels And The Quality Of Life Of Adolecents And Young Adults On Hemodialysis: A Descriptive Correlational Study, Carlisa Waldman
Master of Science in Nursing Theses
Background: End stage renal disease (ESRD) is a permanent condition where the kidneys are unable to function at a level acceptable to sustain life. Dialysis or kidney transplantation are some of the treatments available to maintain patients’ health and well-being. The prevalence of adolescent and young adult patients living with end stage renal disease (ESRD) is increasing. According to the United States Renal Data System (2013), there are over 7,500 patients ages 19 years or younger with ESRD. More than 1,400 of these patients are receiving hemodialysis, this is a national increase of 10.1% for this age group from …
A Clinically Significant Interaction Between Tacrolimus And Multiple Proton Pump Inhibitors In A Kidney Transplant Recipient, Michelle Maguire, Thaddeus T. Franz, David S. Hains
A Clinically Significant Interaction Between Tacrolimus And Multiple Proton Pump Inhibitors In A Kidney Transplant Recipient, Michelle Maguire, Thaddeus T. Franz, David S. Hains
Pharmacy Practice Faculty Publications
The shared metabolism of PPIs and tacrolimus through the CYP enzyme system has been associated with clinically significant drug interactions, especially in patients who are classified as CYP 2C19 PMs. However, existing data are conflicting, indicating that a single mechanism does not account for all interactions. A drug interaction between tacrolimus and omeprazole, esomeprazole, but not lansoprazole, occurred in an 18-yr-old female kidney transplant recipient classified as a CYP 2C19 extensive (normal) metabolizer. This case suggests that further research is needed to establish the definitive mechanism of this potentially serious drug–drug interaction. Physicians prescribing PPIs in organ transplant recipients with …