Medicine and Health Sciences Commons^™

Vascular And Auditory Changes After Repetitive Traumatic Brain Injury, Courtney Lynn Penn

USF Tampa Graduate Theses and Dissertations

Traumatic brain injury (TBI) affects over 2.87 million people in the US each year. The large majority of these injuries can be classified as mild. However, evidence suggests that even mild TBIs can lead to long-lasting symptoms that greatly impact quality of life. This is particularly true when an individual sustains multiple TBIs (repetitive TBI, rTBI). Much of the damage caused by rTBI is due to secondary injury mechanisms that cause the initial injury site to spread and worsen over time. No therapies currently exist which can mitigate secondary injury, and monitoring this phase of rTBI is difficult. Development of …

Sleep Issues Of Older Adults: Lived Experience And Occupational Performance, Emily Angell, Anna Johnston, Adriana C. Mallett, Cassidy Ward, Rachel Wiltse

Culminating Experience Projects

Introduction: Sleep issues are prevalent among older adults which can affect occupational performance; however, there is a gap in the research in examining lived experiences of this population. This research may provide insight into these areas concerning this population.

Method: This qualitative phenomenological study was conducted via semi-structured interviews which were recorded. No identifiable information was collected during data collection. The inclusion criteria of the study sample were as follows: (a) aged 65 years or older; (b) have sleep issues or self-perceived sleep issues; (c) community-dwelling; (d) English is primary language; (e) live in West and Central Michigan. Exclusion criteria …

The Influences Of The Mindfulness Ambassador Program On Graduate Students, Varsha Vasudevan

Electronic Thesis and Dissertation Repository

The two-fold primary purpose of this pilot study was to: (1) explore, qualitatively, the influence of the Mindfulness Ambassador Program (MAP) on graduate students’ experiences of stress and their relationship with themselves and meaningful others; and (2) investigate, quantitatively, if participation in the MAP elicited changes in graduate students’ levels of stress, self-awareness, interpersonal skills, and/or social connectedness. The secondary purpose of this study was to gain an understanding of graduate students’ satisfaction with the MAP. This one-group mixed-method study utilized a brief demographic questionnaire, open-ended questions, semi-structured interviews, two MAP-specific program questionnaires, the Perceived Stress Scale, the Situational Self-Awareness …

Withaferin A And Immune Checkpoint Blocker Therapy For The Treatment Of Non-Small Cell Lung Cancer, Roukiah Khalil

USF Tampa Graduate Theses and Dissertations

Lung cancer is the first cause of cancer-related deaths in both men and women with an overall five-year survival rate of 28%. Although immune checkpoint blockers (ICBs) are currently FDA-approved for the treatment of non-small cell lung cancer (NSCLC), only 17-20% of patients achieve durable responses by the induction of immunologic memory. The lack of response in most patients can be attributed to the tumor-intrinsic or tumor-extrinsic immune resistance mechanisms. A biomarker of importance is the Programmed Death Ligand-1 (PD-L1), as higher PD-L1 expression is usually associated with a better response to ICBs. Although studies have attempted to combine ICBs …

Investigation Of Permanent Tattoos To Increase Myoelectric Signal Connectivity In Prosthetics, Guy Pugh

Master of Science in Kinesiology

Myoelectric prosthetics offer users increased functionality in many facits of their lives. However, maintaining reliable connectivity between sEMG sensors and targeted muscle locations can be problematic. Volume fluctuation of the residual limb, dirt, sweat, and movement of the socket and sensor over the limb can all because of signal disruption leading some users to find the myoelectric prostheses, costing thousands of dollars, to be unreliable, and stop using it. To increase connectivity between the optimal myoelectric sites and sEMG sensors, this paper proposes the use of permanent ink tattoos to create a stable location which a sensor can move over …

A 10 S: 5 S High-Intensity Interval Training Regime Improves Rowing Performance In Varsity And International Class Rowers, Braden J. Reid

Electronic Thesis and Dissertation Repository

The purpose of this study was to investigate the effects of a high-intensity interval training regime with elite collegiate rowers on their rowing performance. A total of 10 interval training sessions were performed over a four-week period with four males and five females completing all pre-testing performance and training sessions. Participants completed a 2000 m performance test to determine initial training intensity. The interventional training sessions consisted of 30 min of 10 s work: 5 s recovery. The 10 s mean power output improved 17% from training session one to ten. The moderate-intensity increased by 44%; mean power output over …

Improving The Mental Health Nursing Competencies Of Nurses Caring For Patients With History Of Substance Use Disorder In Long-Term Care Settings, Nancyver Lafleur-Omeler

Doctor of Nursing Practice Projects

Background

While nurses are often on the front lines of working with patients with a history of substance use disorders (SUD), most have limited training in this area. Nurses who work in Long Term Care (LTC) settings are often challenged to resolve the practical issue of needing more competency in caring for SUD patients. Horner et al. (2019) agreed that the deficiency of mental health knowledge and skills in healthcare workers is linked to decreased quality of care, which can diminish patient outcomes. This lack of competency must be addressed (Margoliese & Vandyck, 2019).

Purpose

The goal of this project …

A Music Therapy Protocol For Pain Management In Individuals With Cerebral Palsy, Zoe Reddick

Music Therapy Theses

The purpose of this project was to develop an individualized Management for Differing Types of Pain in Cerebral Palsy: Music Therapy Protocol on the use of music therapy for pain management and reduction with individuals with cerebral palsy. Most studies addressing pain and music therapy do not investigate the cerebral palsy population. Therefore, a synthesis of the current literature of pain and music therapy informed the development of this protocol. Many individuals in this population experience pain daily and research investigating pain management for this population is needed. The protocol developed outlines interventions to reduce pain specific to the cerebral …

Understanding Influenza Vaccine Hesitancy And Uptake Among U.S. Hispanic Adults During The Covid-19 Pandemic, Helen J. Arteaga

Dissertations and Theses

The health burden caused by seasonal flu is substantial in the general population and each season targeted efforts are needed to decrease the risk of flu illness, hospitalization, and death. Flu risks and the disease burden are disproportionately higher among Hispanic adults, yet little is known about the factors influencing flu vaccine hesitancy and uptake among this marginalized population. This cross-sectional quantitative study used national survey data from the Understanding America Study (UAS) and logistic regression to address three research aims. Aim 1 was to examine the most significant demographic factors associated with flu vaccine uptake among the Hispanic community. …

An Outcome Comparison Of Osseointegrated And Traditional Socket-Fit Prostheses, Alexander Hennes

Master of Science in Kinesiology

This is one of the first studies to report on the comparison of walking ability between socket-based and osseointegrated bone-anchored prostheses of the trans-femoral amputee. Each participant's hip active and passive range of motion was assessed. The Timed Up-and-Go test (TUG), 10-meter walk test (10MWT), and 6-minute walk test (6MWT) were administered to all participants with the addition of the Amputee Mobility Predictor with a Prosthesis (AMPPro). The study consists of unilateral transfemoral amputees with an activity level of K3-4. The current prosthetic users were divided into two groups based on their current intervention, socket prosthesis (S) and osseointegrated prosthesis …

Understanding The Effects Of Empathy And Masculine Gender Role Stress On The Relationship Between Gender And The Understanding Of Consent In Adolescents: A Moderated Mediation Framework, Kate Degenhardt

Clinical Psychology Dissertations

This research examined the relationship between masculine gender role stress and empathy in youths ages 11-19 and their ability to understand the concept of consent. I examined a moderated mediation model where the effect of gender on the understanding of consent via masculine gender role stress was permitted to differ as a function of levels of empathy. The moderated mediation was evaluated in a stepwise fashion. A simple mediation examining the degree to which MGRS mediated the relation of gender on consent revealed all effects were significant, including the indirect effect (B = 0.561, SE = .292 95, CI 0.100, …

A Healthcare Claims Investigation Of Parasomnia Epidemiology, Associations With Attention Deficit/Hyperactivity Disorder, And Rem Sleep Behavior Disorder Correlates, Anh Thy Ha Nguyen

USF Tampa Graduate Theses and Dissertations

Parasomnias, such as sleepwalking and nightmare disorder, are abnormal behaviors and emotions emanating from sleep or wake to sleep transitions. Parasomnias can lead to significant adverse outcomes – sleepwalking can result in injuries and hospitalizations, frequent nightmares are associated with self-harm and suicidal thoughts, and rapid-eye movement (REM) sleep behavior disorder (RBD) is linked to neurodegeneration. Despite a history of fascination with abnormal sleep behaviors in the general and medical communities, epidemiologic understanding of parasomnias remains limited, in part due to their amnestic nature and presumption that they are benign childhood problems. This work used the MarketScan® Commercial Claims and …

Valued Strategies In The Development And Implementation Of Interprofessional Education Placements, Olajumoke Akintomide

Electronic Thesis and Dissertation Repository

Background: Interprofessional education (IPE) is increasingly being recognized as an essential component of training future healthcare providers. IPE allows students to learn collaboratively preparing them for future collaborative practice. Purpose: This study aimed to identify strategies valued by rehabilitation therapy students and clinical instructors in the development and implementation of IPE placements. Method: Through interviews and focus groups, this study explored the experiences and perspectives of students and clinical instructors regarding IPE placements for students in rehabilitation therapy programs. Results: Four major themes emerged from the findings of this study relating to the development and implementation of IPE placements. Themes …

A Computational Model Of Multiple Interconnected Capillary Modules In Skeletal Muscle, Raashi Vijay

Electronic Thesis and Dissertation Repository

Background: Skeletal muscle (SM), with its precise O₂ supply-demand matching, is ideal for studying microvascular (MV) function, which is crucial in cardiovascular physiology and disease. Our goal is to gain understanding of SM microcirculation using recent capillary network module (CM) data from rat in a computational model.

Methods: We construct a 4-CM network, with single-vessel equivalents for each CM, three arterioles, and two venules. A two-phase (plasma/RBCs) steady-state model is used to calculate blood flow. An iterative boundary pressure finding method is developed to match flow in CMs.

Results: We validate our flow and pressure models …

“I’M Still Suffering”: Mental Health Care Among Central African Refugee Populations In The Tampa Bay Area, C. Danee Ruszczyk

USF Tampa Graduate Theses and Dissertations

An estimated 500 Central African refugee families have been resettled in the Tampa Bay Area since 2002 (RPC, 2022). The cycles of trauma that they have endured place them in vulnerable positions regarding their mental health. Struggling to exist within underfunded social programs that are rigid in their expectations and with the current system of reactive care vs preventative care, the refugees in Tampa are put in a difficult situation of navigating their own health and wellbeing in lieu of having the full support of the United States government and their community. I will discuss how these refugees experience and …

Assessment Of Iso Heart Rate Method To Estimate Metabolic Rate, Karl Williams

USF Tampa Graduate Theses and Dissertations

Thermal equilibrium is primarily maintained by the body’s ability to dissipate internal heat generated during muscle contraction. A number of methods have been used to quantify this thermal burden such as charts and observation of workplace activities and behavior, however these have varying levels of validity. ISO 8996 defines a more accurate method of metabolic rate estimation that uses heart rate and maximal work capacity (MWC); however this requires the use of laboratory settings and equipment that are rarely available in the field. Equations such as the ACSM metabolic equation for the total energy expenditure of walking, hereafter referred to …

Investigating The Role Of Endothelial Breast Cancer Susceptibility Gene 2 In Doxorubicin-Induced Cardiotoxicity, Berk U. Rasheed

Electronic Thesis and Dissertation Repository

Doxorubicin (Dox) is a chemotherapeutic drug used to treat various malignancies including breast and ovarian cancers. Accumulating evidence implicates cardiac impairments associated with Dox treatment. The Breast Cancer Susceptibility Gene 2 (BRCA2) functions to maintain genome-wide stability by promoting DNA-damage repair. Accordingly, cardiomyocyte damage is specifically regulated by contributors of DNA damage repair such as BRCA2. The endothelium, the innermost cells of every blood vessel, act to protect our tissues from noxious elements, however, recent evidence suggests that BRCA2 knockdown compromises endothelial cell function. A putative role of endothelial BRCA2 during Dox-induced cardiotoxicity (DIC) remains unknown. We hypothesized that endothelial-specific …

Reasoning The Voice: Toward A Diagnostic And Prescriptive Technique In The Teaching Of Singing, Carlos E. Santelli

LSU Doctoral Dissertations

Voice pedagogy literature often draws a parallel between a doctor’s ability to diagnose illness and prescribe treatment, and a voice teacher’s ability to identify vocal obstacles and design solutions. The core of these parallel procedures lies in an ability to utilize critical reasoning skills within highly specific contexts. Medical literature describes this as “clinical reasoning” and has studied it as a learned process. Voice pedagogy literature has traditionally described this as an innate process which is solely developed through experience. This document broadly examines the ways in which medical literature has broken down clinical reasoning into specific cognitive processes and …

Evaluation Of Two Methods To Estimate Wet Bulb Globe Temperature From Heat Index, Stephi Pofanl

USF Tampa Graduate Theses and Dissertations

The Wet bulb globe temperature (WBGT) is a common method to evaluate environmental factors that contribute to occupational heat stress. The Heat Index (HI) is readily available as an alternative to exposure methods. They both assess the most important contributors that are air temperature and humidity. WBGT also includes radiant heat and air motion. To account for radiant heat and/or air motion, some investigators have suggested adjustments to HI. The purpose of this study is to explore two methods to estimate the usefulness of WBGT from HI.

WBGT data were collected in a variety of locations that included direct sun …

Differential Levels Of Nutrients And Heavy Metals In Tilapia Collected From Drains In Egypt, Emily Burch

Theses and Dissertations

Tilapia is one of the most widely cultivated and consumed fish globally. In terms of human health, tilapia is an excellent source of protein, polyunsaturated fatty acids, and micronutrients. Tilapia and other aquatic species have become increasingly susceptible to contamination, as anthropogenic activities have been increasing around the world. Anthropogenetic activities often introduce high levels of contaminants, including heavy metals, into the marine environment. These contaminants often do not biodegrade, and they are absorbed by aquatic species. Contaminants can bioaccumulate and proceed in biomagnification up the fish food chain putting consumers at an increased risk of exposure. Heavy metals can …

Effects Of Age On Amplitude-Modulated Cvemp Temporal Modulation Transfer Function, Raghav H. Jha

Dissertations, 2020-current

With the aging population on the rise, the need for effective assessment tools to identify risk factors for falls among the elderly is paramount. One independent risk factor for falls is vestibular impairment, but the available vestibular diagnostic tests have limitations. A promising new methodology: amplitude-modulated tones to elicit a vestibular-evoked myogenic potential (AMcVEMP), offers a more detailed examination of vestibular (sacculo-collic reflex) functions. This method assesses non-linearities, synchrony, and magnitude, providing a more thorough evaluation compared to the conventional transient cVEMP. So far, AMcVEMP has only been utilized in young adults.

The current study aimed to investigate the impact …

Longitudinal Dynamics Of Cerebrospinal Fluid Aꞵ, Ptau And Strem2 Reveal Predictive Preclinical Trajectories Of Alzheimer’S Pathology, Bahaaldin Helal

Electronic Thesis and Dissertation Repository

Alzheimer's disease (AD) is a prevalent neurodegenerative disorder with limited early-stage treatment options. There is an urgent and unmet need for accurate biomarkers which can identify patients at risk for AD before cognitive symptoms emerge. Here I compared the performance of two analytical methods, univariate and multivariate classification, for identifying cognitively normal (CN) and mild cognitive impairment (MCI) patients based on their cerebrospinal fluid (CSF) biomarkers of Aβ42, pTau-181, sTREM2. Post-hoc analyses were then employed to assess patient progression in each of the SNF clusters. I found that SNF identified subgroups within the CN and MCI cohorts, based solely on …

Improving The Subjective Well-Being Of Autistic Youth Utilizing A Positive Psychology Intervention, Nicolette Bauermeister

USF Tampa Graduate Theses and Dissertations

This study utilized a single-case multiple-baseline design to analyze the effects of a ten-week multi-component positive psychology intervention, the Well-Being Promotion Program, on the subjective well-being of Autistic youth. This thesis addressed a gap in the literature regarding the effectiveness of positive psychology interventions when administered to Autistic middle schoolers. Three Autistic middle schoolers participated in this single-case design study. Dynamic decision-making was used to stagger intervention implementation across the three participants. Life satisfaction and positive/negative affect data were collected via a Qualtrics survey that was administered twice per week. Through visual analysis and Baseline Corrected Tau calculations, it was …

Development Of A Ddpcr Multiplex To Measure The Immune Response To Borrelia Burgdorferi., Kailey Marie Mccain

USF Tampa Graduate Theses and Dissertations

Zoonotic diseases account for a significant proportion of emerging infectious diseases (EIDs), with their dynamics being heavily influenced by the environment. While the effects of the environment on population-level disease dynamics have been extensively studied, there is limited research investigating the impact of the environment on individual-level disease susceptibility and transmission. This study aims to fill this gap by creating a tool to examine the variation in immune response to Borrelia burgdorferi, the causative agent of Lyme Disease, in two competent host species, Peromyscus leucopus and Peromyscus maniculatus. Two triplex droplet digital polymerase chain reaction (ddPCR) assays were developed to …

A Study On The Correlation Between The Study Habits Of Nursing Students And Perceived Exam Anxiety, Rebecca A. Bracken

Honors College Theses

Anxiety is a concept very familiar to many university students. This especially applies to students who have decided to major in nursing. With the knowledge and experiences that accompany attending nursing school, come a series of rigorous, high-stakes exams. Nationwide, many students share a common struggle to be successful on these exams, which often leads to a sense of anxiety that becomes associated with one's experience during testing, known as test anxiety. A study across multiple baccalaureate nursing school cohorts was completed to determine a correlation between the various methods used by nursing students to prepare for an exam and …

Global Health Governance And Its Role In Health Equity: The Case Of Covid-19, Wafa Abu El Kheir-Mataria

Theses and Dissertations

In the globalized world, we are living in, health became the joint responsibility of individuals, their governments, and the global health governance system. Moreover, based on the right to health, health equity is increasingly in demand, and adopting it to a global level has become an even more complex task to realize. This thesis is focuses on health equity at a global level. The main research questions addressed are: Is health equity present at an intercountry /global level? how is it related to Global Health Governance (GHG)? Is GHG performing well in achieving health equity? what are the reasons behind …

Let Kids Sleep: The Role Of Interdisciplinary Neuroscience Outreach In Stimulating Brains And Developing Research-Informed Approaches To Community Concerns, Marc Chenard

University Honors Theses

Northwest Noggin (NW Noggin), an all-volunteer neuroscience education outreach non-profit, serves its community by bringing students, artists, scientists and other participants together for artistic collaboration and learning. The outreach takes place in K-12 schools and other institutions (such as museums, coffee shops and correctional facilities) all over the Pacific Northwest. Neuroscience education outreach generates discourse surrounding community concerns through illuminating the brain-centric qualities of issues and by drawing on neuroscience research to create solutions. The neuroscience research-informed perspectives on these concerns stimulate awareness, create momentum towards evidence-based reform, and can result in policy interventions. This thesis details how NW Noggin …

The Association Of Patient-Provider Language Concordance With Healthcare Comprehension Among Latino/As In Oregon, Grace Parra

University Honors Theses

Background: The purpose of this study is to describe the need and preferences among Mexican-origin Latinos in Oregon for language-concordant healthcare providers. We hypothesize that the presence of a language concordant provider is associated with greater health care comprehension.

Methods: This is a cross sectional study in collaboration with the General Consulate of Mexico. We developed a 20-item survey that includes questions about socio-demographics, a validated language-based acculturation scale, and questions regarding language concordant care experience and preferences used in previous studies. We are recruiting at the Mexican Consulate 500 Latino/as ages 18 or older who had a healthcare visit …

The Impact Of Period Poverty On Low-Income Adolescents In The United States, Makayla Olson

University Honors Theses

Period poverty is an issue that impacts menstruators globally. This creates a significant health disparity for menstruators, including difficulties accessing menstrual products, inadequate menstrual and puberty health education, and shame and stigma that come from societal misunderstandings and misinformation regarding menstruation. This paper examines the effects of period poverty on low-income adolescents in the United States. It looks at the current literature that addresses how the financial and accessibility barriers that cause period poverty, as well as how these causes impact school-aged menstruators. It aims to address the role that schools play in creating safe environments for menstruators, including staff …

Resistance Training And Running Performance And Economy: A Literature Review, James Bottrill

University Honors Theses

Running performance is largely determined by maximal oxygen uptake (VO₂ max), velocity at VO₂ max, fractional utilisation of VO₂ max and running economy. Running economy is relatively under-researched and could be improved by resistance training because of its neuromuscular underpinnings. However, existing research on this topic is quite unorganised and inconclusive and is yet to prove a direct linkage between resistance training, running economy and performance. This literature review aimed to provide an organised overview of the existing literature, identify and address confounding variables and provide recommendations for future research. A search for studies was conducted via …