Medicine and Health Sciences Commons^™

Time Course Of Cocaine-Induced Behavioral And Neurochemical Plasticity, Victoria Lutgen, Linghai Kong, Kristen S. Kau, Aric Madayag, John Mantsch, David A. Baker

Biomedical Sciences Faculty Research and Publications

Factors that result in augmented reinstatement, including increased withdrawal period duration and high levels of cocaine consumption, may provide insight into relapse vulnerability. The neural basis of augmented reinstatement may arise from more pronounced changes in plasticity required for reinstatement and/or the emergence of plasticity expressed only during a specific withdrawal period or under specific intake conditions. In this study, we examined the impact of withdrawal period duration and cocaine intake on the magnitude of cocaine-primed reinstatement and extracellular glutamate in the nucleus accumbens, which has been shown to be required for cocaine-primed reinstatement. Rats were assigned to self-administer under …

Composition, Phase Structure, And Corrosion Of Nickel-Free And Nickel-Containing Stainless Steel Orthodontic Wires, Amrita Rakalla

Master's Theses (2009 -)

Stainless steel wires have long been used in orthodontics. The austenitic stainless steel used in orthodontics contains approximately 18 wt% chromium and 8 wt% nickel. Nickel improves the corrosion resistance and helps maintain the austenite structure of stainless steel. Nickel is the most allergenic metal and is the most common metal associated with contact dermatitis in orthodontics. Nickel-free wires have been developed, and it was the goal of this study to compare nickel-free and nickel-containing stainless steel orthodontic wires to determine and compare their composition, phase structure, and corrosion properties. For each test, nickel-free and conventional stainless steel wires were …

An Investigation Into The Bonding Properties Of New Generation Ceramic Brackets As Compared To A Stainless Steel Bracket, Ami Inoue

Master's Theses (2009 -)

Introduction: More patients are seeking esthetic alternatives for their orthodontic treatment options, which has led to increased use of ceramic brackets in recent years. These brackets were marketed before independent scientific research was completed. Many of the early ceramic brackets used a silane coupling agent to allow for a chemical bond between the bracket and the adhesive resin. Early reports from clinicians of increased bond strengths and iatrogenic tooth damage after bracket removal were common. Manufacturers have made changes to their base designs, relying more on mechanical retention for bond strength. The goal of this study was to test the …

Comparing The Vertical Misfit Of Casts Produced By Two Verification Jigs, Abdulaziz Saeed Alqahtani

Master's Theses (2009 -)

Purpose: To compare the dimensional accuracy between master casts fabricated with verification jigs made of acrylic resin and light cure Triad. Materials and Methods: 10 GC Pattern resin Pattern verifications jigs and 10 Triad gel verification jigs fabricated of a master cast of a mandibular model of 4 internal hex implants. A stone base was fabricated for each verification jig. One screw test was used to evaluate the vertical gap at the terminal abutment using a digital micrometer with an accuracy of 1μm to record the vertical gap for each sample. Results: Triad Gel group has the lowest average distortion …

Dimensional Changes Of Facial Soft Tissue Associated With Rapid Palatal Expansion, Peter Charles Longo

Master's Theses (2009 -)

Introduction: Orthodontic treatment demands excellent outcomes in both function and esthetics. Despite the popularity of rapid palatal expansion in orthodontic treatment, few studies have examined its consequences on facial soft tissue using direct anthropometric measurements. The primary goal of this study was to determine facial soft tissue changes immediately following rapid palatal expansion. Materials and Methods: Twenty-eight patients (age range, 8-17 years) attending Marquette Dental School Orthodontic Post-Graduate Clinic were enrolled in the study. Facial soft tissue measurements were taken with digital calipers at two separate time points (T0: initial exam and T1: thirty days following expansion); measurements were recorded …

Effect Of Mechanical Vibration On Resistance To Sliding In The Fixed Orthodontic Appliance, David Robert Kennedy

Master's Theses (2009 -)

Objective: To determine the effects of mechanical vibrations produced from electric tooth brushes and a commercially available device called AcceleDent, on the resistance to sliding at the bracket-arch wire interface. Materials and Methods: All as-received wires and brackets were cleaned with 95% ethanol prior to testing. An individual metal bracket was mounted on a custom metal fixture. The custom metal fixture had a polyurethane material that resembled the mechanical feature of the human periodontal ligament. The test metal bracket was aligned and bonded passively with 4 other non-movable brackets using a straight piece of .0215" X .025" SS wire. Another …

Mechanisms Of Isometric Exercise-Induced Hypoalgesia In Young And Older Adults, Kathy J. Lemley

Dissertations (1934 -)

Pain reduction following exercise (exercise-induced hypoalgesia; EIH) is well-established in young adults. Specific to isometric exercise, the greatest EIH follows low intensity contractions held for long duration. The EIH response of older adults is not known; and the mechanisms for EIH are unclear at any age. This dissertation aimed to address these unknowns through a series of three studies. In study one, repeatability of pressure pain reports (pain threshold and pain ratings) was assessed in healthy older adults, including the impact of psychological factors. Pain reports, measured before and after quiet rest, did not change following quiet rest. Higher state …

Self-Assessed Health In Caregivers Of Persons With Autism: Associations With Depressive Symptoms, Positive Cognitions, Resourcefulness, And Well-Being, Abir K. Bekhet

College of Nursing Faculty Research and Publications

Purpose

Caregiving for children with autism spectrum disorder (ASD) can affect family caregivers' self-assessed health. The purpose of this study was to determine whether depressive symptoms, positive cognitions, resourcefulness, and well-being will differ significantly among those who rated their health as fair, good, or excellent.

Design and Methods

This study is a secondary analysis of 109 ASD caregivers who were recruited from the Interactive ASD Network.

Findings

Depression was significantly lower among those who rated their health as excellent than among those who rated their health as fair. Positive cognitions, resourcefulness, and well-being were significantly higher among those who rated …

A Comparison Of Two Formulas Of Topical Menthol On Vascular Responses And Perceived Intensity Prior To And Following A Bout Of Maximum Voluntary Muscular Contractions (Mvmcs), Robert V. Topp, Alex V. Ng, Alyson Cybulski, Katalin W. Skelton, Paula Papanek

College of Nursing Faculty Research and Publications

The purpose of this study was to compare the vascular responses in the brachial artery and perceived intensity of two different formulas of topical menthol gels prior to and following a bout of maximum voluntary muscular contractions (MVMCs).

18 adults completed the same protocol on different days using blinded topical menthol gels (Old Formula and New Formula). Heart rate, brachial artery blood flow (ml/min), vessel diameter and reported intensity of sensation were measured at baseline (T1), at 5 min after application of the gel to the upper arm (T2), and immediately following five MVMCs hand grips (T3).

The New Formula …

Inhibition Of Food Intake By Pacap In The Hypothalamic Ventromedial Nuclei Is Mediated By Nmda Receptors, Jon M. Resch, Brian Maunze, Kailynn A. Phillips, Sujean Choi

Biomedical Sciences Faculty Research and Publications

Central injections of pituitary adenylate cyclase-activating polypeptide (PACAP) into the ventromedial nuclei (VMN) of the hypothalamus produce hypophagia that is dependent upon the PAC1 receptor; however, the signaling downstream of this receptor in the VMN is unknown. Though PACAP signaling has many targets, this neuropeptide has been shown to influence glutamate signaling in several brain regions through mechanisms involving NMDA receptor potentiation via activation of the Src family of protein tyrosine kinases. With this in mind, we examined the Src-NMDA receptor signaling pathway as a target for PACAP signaling in the VMN that may mediate its effects on feeding behavior. …

An Investigation Into The Mechanical And Aesthetic Properties Of New Generation Coated Nickel-Titanium Wires In The As-Received State And After Clinical Use, T. Gerard Bradley, David W. Berzins, Nicholas Valeri, Jessica E. Pruszynski, Theodore Eliades, Christos Katsaros

School of Dentistry Faculty Research and Publications

The orthodontic profession is constantly seeking to improve and optimize the aesthetics of orthodontic wires since the introduction of aesthetic brackets. Nickel-titanium (NiTi) wires since their introduction to orthodontics (Andreasen and Hilleman, 1971) have been extensively researched in vitro and are used as an initial levelling and aligning archwire because of its properties of springback and superelasticity (Burstone et al., 1985; Miura et al., 1986; Leu et al., 1990; Bishara et al., 1995; Bradley et al., 1996; Biermann et al., 2007; Berzins and Roberts 2010). Aesthetic wires are usually either coated NiTi wires or composite wires of reinforced polymers. Shape …

Patient Perceptions Of Patient-Empowering Nurse Behaviours, Patient Activation And Functional Health Status In Postsurgical Patients With Life-Threatening Long-Term Illnesses, Teresa Jerofke-Owen, Marianne E. Weiss, Olga Yakusheva

College of Nursing Faculty Research and Publications

Aim

To explore the trajectory of associations between the nursing care process of patient empowerment during postsurgical hospitalization and postdischarge patient self-management outcomes, specifically patient activation and functional health status.

Background

Patient-centred care models advocate for patient empowerment in long-term illness care. Postsurgical patients with life-threatening long-term illnesses frequently feel powerless, have unmet needs, decreased functional health status and high readmission rates; however, previous studies of patient empowerment have conceptualized empowerment as an outcome primarily in outpatient settings, with little attention paid to provider processes used to empower patients during hospitalizations.

Design

A non-experimental, prospective, correlational study.

Methods

This sample …

Psychometric Properties Of The Index Of Relocation Adjustment, Abir K. Bekhet, Jaclene Zauszniewski

College of Nursing Faculty Research and Publications

More and more American older adults are relocating to retirement communities, and they experience challenges in adjusting to new surroundings that may increase their depression and mortality. An instrument not previously tested in the United States, the Index of Relocation Adjustment (IRA), may help in early identification of poor relocation adjustment. This study examined the psychometric properties of the IRA using secondary data from a convenience sample of 104 older adults who relocated to 6 retirement communities in Northeast Ohio. Cronbach’s alpha was .86. The IRA was correlated with measures of positive cognitions (r = .48, p < .01) and relocation controllability (r = …

Strategies For Sustaining Self Used By Family Caregivers For Older Adults With Dementia, Margaret J. Bull

College of Nursing Faculty Research and Publications

The negative health consequences of caring for an older adult family member with dementia are well documented. However, not all family caregivers experience these negative health consequences. The purposes of this study were to describe strategies family caregivers use to help them continue to provide care for an older family member with dementia despite challenges and describe these family caregivers’ resilience and psychological distress. A mixed methods design was used with a narrative approach dominant and standardized scales for resilience and psychological distress used to enhance the description of the sample. Data were collected through telephone interviews with 18 family …

Changes In Glutamate Receptor Subunits Within The Medulla In Goats After Section Of The Carotid Sinus Nerves, Justin Robert Miller, Suzanne Neumueller, Clarissa Muere, Samantha Olesiak, Lawrence Pan, John D. Bukowy, Asem O. Daghistany, Matthew Hodges, Hubert Forster

Physical Therapy Faculty Research and Publications

The mechanisms which contribute to the time-dependent recovery of resting ventilation and the ventilatory CO₂ chemoreflex after carotid body denervation (CBD) are poorly understood. Herein we tested the hypothesis that there are time-dependent changes in the expression of specific AMPA, NMDA, and/or neurokinin-1 (NK1R) receptors within respiratory-related brain stem nuclei acutely or chronically after CBD in adult goats. Brain stem tissues were collected acutely (5 days) or chronically (30 days) after sham or bilateral CBD, immunostained with antibodies targeting AMPA (GluA1 or GluA2), NMDA (GluN1), or NK-1 receptors, and optical density (OD) compared. Physiological measurement confirmed categorization of each …

Sensorimotor Adaptation Of Speech Using Real-Time Articulatory Resynthesis, Jeffrey J. Berry, Cassandra North, Michael T. Johnson

Speech Pathology and Audiology Faculty Research and Publications

Sensorimotor adaptation is an important focus in the study of motor learning for non-disordered speech, but has yet to be studied substantially for speech rehabilitation. Speech adaptation is typically elicited experimentally using LPC resynthesis to modify the sounds that a speaker hears himself producing. This method requires that the participant be able to produce a robust speech-acoustic signal and is therefore not well-suited for talkers with dysarthria. We have developed a novel technique using electromagnetic articulography (EMA) to drive an articulatory synthesizer. The acoustic output of the articulatory synthesizer can be perturbed experimentally to study auditory feedback effects on sensorimotor …

The Electromagnetic Articulography Mandarin Accented English (Ema-Mae) Corpus Of Acoustic And 3d Articulatory Kinematic Data, Jeffrey J. Berry, An Ji, Michael T. Johnson

Speech Pathology and Audiology Faculty Research and Publications

There is a significant need for more comprehensive electromagnetic articulography (EMA) datasets that can provide matched acoustics and articulatory kinematic data with good spatial and temporal resolution. The Marquette University Electromagnetic Articulography Mandarin Accented English (EMA-MAE) corpus provides kinematic and acoustic data from 40 gender and dialect balanced speakers representing 20 Midwestern standard American English L1 speakers and 20 Mandarin Accented English (MAE) L2 speakers, half Beijing region dialect and half are Shanghai region dialect. Three dimensional EMA data were collected at a 400 Hz sampling rate using the NDI Wave system, with articulatory sensors on the midsagittal lips, lower …

Treatment Of Abscessed Primary Molars Utilizing Lesion Sterilization And Tissue Repair: Literature Review And Report Of Three Cases, David Burrus, Lori Barbeau, Brian D. Hodgson

School of Dentistry Faculty Research and Publications

Purpose: The purpose of this report was to review an emerging alternative treatment to pulpectomies and extractions for nonvital primary teeth called lesion sterilization and tissue repair (LSTR) and provide the results of three clinical case applications. LSTR is a noninstrumentation endodontic treatment that involves a triantibiotic mixture in a propylene glycol vehicle, which is used to disinfect root canal systems. This concept was developed by the cariology research unit of the School of Dentistry, Niigata University, Niigata, Niigata Prefecture, Japan. This article reviews the development of the technique, clinical procedures required for the technique, three clinical applications and radiographic …

Do You Use Your Professional Code Of Ethics?, Kathryn Schroeter

College of Nursing Faculty Research and Publications

No abstract provided.

Psychometric Properties Of The Resourcefulness Scale Among Caregivers Of Persons With Autism Spectrum Disorder, Abir K. Bekhet, Jaclene Zauszniewski

College of Nursing Faculty Research and Publications

Caregiving for children with autism spectrum disorder (ASD) can be very costly to caregivers’ well-being. Resourcefulness interventions have shown increases in positive health outcomes. However, before delivering the intervention, there should be a reliable and a valid measure to test resourcefulness. The psychometric properties of the Resourcefulness Scale (RS) have not been examined among ASD caregivers. This study examined the psychometrics of the 28-item RS in a convenience sample of 204 ASD caregivers. A Cronbach’s alpha of .91 showed the internal consistency of the RS. Construct validity was supported by the emergence of two dimensions of resourcefulness (personal and social) …

Use Of Ovulation Predictor Kits As Adjuncts When Using Fertility Awareness Methods (Fams): A Pilot Study, Rene Letva, Ula Burban, Edmond Kyrillos, Richard Fehring, Robin Mclaren, Catherine Dalzell, Elizabeth Tanguay

College of Nursing Faculty Research and Publications

Purpose: Difficult clinical signs such as confusing cervical mucus or erratic basal body temperature can make the use of fertility awareness methods (FAMs) difficult in some cases. The goal of this study was to assess the feasibility of using a cheap urinary luteinizing hormone (LH)–surge identification kit as an adjunct to identify the infertile phase after ovulation when facing these scenarios.

Methods: The study used a block-allocation, crossover, 2-arm methodology (LH kit/FAM vs FAM only). Comparison of the 2 arms was done with regard to the accuracy of identification (yes/no) of the luteal phase in each cycle as confirmed by …

Cohort Efficacy Study Of Natural Family Planning Among Perimenopause Age Women, Richard Fehring, Qiyan Mu

College of Nursing Faculty Research and Publications

Objective: To determine the efficacy of using natural family planning (NFP) methods to avoid unintended pregnancy among women of perimenopause age (i.e., age 40-55 years).

Design: A secondary analysis of subset data from two prospective observational cohort studies.

Setting: A university based in-person and online NFP service program.

Participants: One hundred and sixty couples who used either a website or an in-person NFP service to learn how to avoid pregnancy from January 2001 to November 2012.

Methods: A prospective 12-month effectiveness study among 160 women (between ages 40-55) who used NFP to avoid pregnancy. The …

Palliative And End-Of-Life Care: Precepts And Ethics For The Orthopaedic Population, Cheryl L. Petersen, Susan Breakwell, Margaret Callahan

College of Nursing Faculty Research and Publications

Since the emergence of reports such as the National Consensus Project for Quality Palliative Care (2013) and the National Association of Orthopaedic Nurses Palliative Care Consensus Document (2005), there continues to be a growing recognition of the multiple adverse effects of serious illness and chronic conditions, as well as the potential benefits of receiving palliative or end-of-life care. As modern technology expands its ability to support life, ethical dilemmas may be encountered in the provision of palliative or end-of-life care. Through integration of the precepts of palliative care and consideration of the relevant ethical principles, orthopaedic nurses may best meet …

Phd Preparation For Nurse Faculty And Nurse Scientists: Do They Have To Be The Same?, Donna O. Mccarthy

College of Nursing Faculty Research and Publications

No abstract provided.

Feasibility Of Oral Prenatal Probiotics Against Maternal Group B Streptococcus Vaginal And Rectal Colonization, Lisa Hanson, Leona Vandevusse, Megan Duster, Simone Warrack, Nasia Safdar

College of Nursing Faculty Research and Publications

Objective

To examine the effect of an oral prenatal probiotic on group B Streptococcus (GBS) colonization and to demonstrate the feasibility of a larger randomized controlled trial.

Design

This pilot study was an open‐label, two‐group quasi‐experiment.

Setting

An urban central city nurse‐midwifery and wellness center serving a diverse population.

Participants

Ten pregnant participants received the oral probiotic (Florajen3) taken once daily, and 10 participants served as controls.

Methods

A questionnaire on dietary practices, vaginal cleansing, sexual history, and symptoms and GBS colony count samples were taken at 28‐, 32‐, and 36‐weeks gestation.

Results

Participants in the probiotic group reported no …

Accuracy And Precision Of Die Spacer Thickness With Combined Computer-Aided Design And 3-D Printing Technology, Lisa Hoang

Master's Theses (2009 -)

Purpose: The purpose of this study was to evaluate the accuracy and precision of die-spacer thickness achieved by the combination of computer aided design and 3-dimension printing technology.

Materials and Methods: An ivorine maxillary central incisor was prepared for an all ceramic crown. The prepared tooth was duplicated by using poly (vinyl siloxane) duplicating silicone and 80 die-stone models were produced using type IV dental stone. Dies were randomly divided into 5 groups with assigned die spacer thickness of (25 μm, 45 μm, 65 μm, 85 μm, 105 μm) (n=16/group). The printed resin copings, obtained from 3D Systems ProJet DP …

Influence Of Taper On The Flexibility Of Nickel-Titanium Rotary Files, Christopher J. Kingma

Master's Theses (2009 -)

Introduction: Modern nickel-titanium instruments have various tapers and have been marketed to have superior flexibility from previous generations. Current ISO standards require force measurements at a static point along the file. Unfortunately, root canal anatomy varies and produces multiple forces along the length of the file. The purpose of this study was to determine the influence of taper on the flexibility of various nickel-titanium files.

Materials and Methods: The flexibility of stainless steel hand files and nickel-titanium rotary files of various tapers was measured. The sample size was 10 for each type, taper and size. The files were measured at …

Flexibility Of Various Nickel-Titanium Rotary Endodontic Files, Chelsea Selin

Master's Theses (2009 -)

Introduction: Nickel-titanium rotary files were originally developed to allow for greater flexibility when instrumenting root canals. The increased flexibility of nickel-titanium instruments allowed operators to negotiate canal curvatures with greater ease. File design is continually changing. Manufacturers are trying to produce files that will work more efficiently and safely. Knowing the properties of files marketed is especially important in helping to choose an appropriate file system. Current ISO standards require force measurements at a static point along the file. The purpose of this study was to evaluate the flexibility of four different nickel-titanium files at three different points along the …

A Comparison Of Two Methods To Articulate A Maxillary Cast With Lateral Cephalometry, Laura H. Lux

Master's Theses (2009 -)

The Kois Dento-Facial Analyzer, an arbitrary articulation system, is used by clinicians to articulate and evaluate clinical cases. There is, however, limited information for understanding how the Kois Dento-Facial Analyzer should be utilized. Dr. Kois and Dr. Lee originally patented the device in 2003 yet there is essentially no evidence-based research in the literature. The purpose of this study was to evaluate the outcomes of articulating the maxillary cast using the Kois Dento-Facial Analyzer in three-dimensions as compared to the position of the cast when using Panadent’s Pana-Mount Facebow. Fifteen dried human skulls were used as test subjects. Maxillary diagnostic …

3d Visualization Architecture For Building Applications Leveraging An Existing Validated Toolkit, David A. Polyak

Master's Theses (2009 -)

The diagnostic radiology space and healthcare in general is a slow adopter of new software technologies and patterns. Despite the widespread embrace of mobile technology in recent years, altering the manner in which societies in developed countries live and communicate, diagnostic radiology has not unanimously adopted mobile technology for remote diagnostic review. Desktop applications in the diagnostic radiology space commonly leverage a validated toolkit. Such toolkits not only simplify desktop application development but minimize the scope of application validation. For these reasons, such a toolkit is an important piece of a company’s software portfolio. This thesis investigated an approach for …