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Full-Text Articles in Medicine and Health Sciences
The Effect Of Pentylenetetrazole-Induced Seizures On Blood-Brain Barrier Integrity In A Rat Model Of Preeclampsia, Mutlu Küçük, Mehmet Kaya, Nurcan Orhan, Oğuzhan Eki̇zoğlu, Erol Arslan, Nadi̇r Arican, Rabi̇a Candan Gürses, İmdat Elmas, Ri̇vaze Kalayci, Bülent Ahishali
The Effect Of Pentylenetetrazole-Induced Seizures On Blood-Brain Barrier Integrity In A Rat Model Of Preeclampsia, Mutlu Küçük, Mehmet Kaya, Nurcan Orhan, Oğuzhan Eki̇zoğlu, Erol Arslan, Nadi̇r Arican, Rabi̇a Candan Gürses, İmdat Elmas, Ri̇vaze Kalayci, Bülent Ahishali
Turkish Journal of Veterinary & Animal Sciences
The pathophysiological mechanisms underlying blood-brain barrier (BBB) disruption in preeclampsia/eclampsia have not been elucidated. This study investigated the effect of pentylenetetrazole (PTZ)-induced seizures on the functional and structural properties of the BBB during N (omega)-nitro-L-arginine methyl ester (L-NAME)-induced hypertension and proteinuria in pregnant rats. Animals were treated with L-NAME for 10 days, beginning on day 10 of pregnancy. The BBB permeability was determined by measurements of sodium fluorescein (NaFlu) extravasation into the brain. Occludin and aquaporin (AQP)-4 immunoreactivities were evaluated in brain sections. Severe proteinuria and significantly increased arterial blood pressure were observed following L-NAME treatment. PTZ-induced seizures in pregnant …
Fecal Progesterone Analysis For Monitoring Reproductive Status In Dairy Goats, Amelia Miranda Morgiana Jack, Chao-Chin Chang, Huo-Cheng Peh, Jacky Peng-Wen Chan
Fecal Progesterone Analysis For Monitoring Reproductive Status In Dairy Goats, Amelia Miranda Morgiana Jack, Chao-Chin Chang, Huo-Cheng Peh, Jacky Peng-Wen Chan
Turkish Journal of Veterinary & Animal Sciences
The present study was undertaken to evaluate the use of fecal progesterone (FP_4) concentration for early pregnancy diagnosis, estrus detection, and predicting the litter size and parturition date in dairy goats. Fecal samples were collected from 17 hand-mated goats 3 times a week for 22-23 weeks, beginning on the day of mating. The levels of FP_4 were determined by enzyme-linked immunosorbent assay (ELISA). Significant positive correlations were found between the levels of serum P_4 and FP_4 (r = 0.8787, n = 13). Pregnancy diagnosis was performed at 2 months postmating with transabdominal ultrasonography and confirmed upon birth of the offspring. …