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Veterinary Medicine

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2012

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Full-Text Articles in Medicine and Health Sciences

Exclusion Of Rpgrip1 Ins44 From Primary Causal Association With Early-Onset Cone–Rod Dystrophy In Dogs, Tatyana Kuznetsova, Simone Iwabe, Kathleen Boesze-Battaglia, Sue Pearce-Kelling, Yim Chang-Min, Kendra Mcdaid, Keiko Miyadera, Andras Komaromy, Gustavo D. Aguirre Jul 2012

Exclusion Of Rpgrip1 Ins44 From Primary Causal Association With Early-Onset Cone–Rod Dystrophy In Dogs, Tatyana Kuznetsova, Simone Iwabe, Kathleen Boesze-Battaglia, Sue Pearce-Kelling, Yim Chang-Min, Kendra Mcdaid, Keiko Miyadera, Andras Komaromy, Gustavo D. Aguirre

Gustavo D. Aguirre, VMD, PhD

Purpose.: Canine cone–rod dystrophy 1 (cord1) has been previously mapped to CFA15, and a homozygous 44-bp insertion in exon 2 (Ins44) of canine RPGRIP1(cRPGRIP1Ins/Ins ) has been associated with the disease. However, from the recent identification of a significant discordance in genotype–phenotype association, we have reexamined the role of cRPGRIP1 in cord1.
Methods.: Retinal structure and function was assessed by clinical retinal examination, noninvasive imaging, electroretinography, and histopathology/immunohistochemistry. cRPGRIP1 splicing was analyzed by RT-PCR. Retinal gene expression was determined by quantitative RT-PCR (qRT-PCR). Five markers spanning the entire cRPGRIP1 were identified and used for haplotyping. …

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A Biography Of And Interview With Charles W. Raker, Vmd, Sarah Khatibzadeh Feb 2012

A Biography Of And Interview With Charles W. Raker, Vmd, Sarah Khatibzadeh

Charles W. Raker (1920 - 2014)

Charles W. Raker was one of the leading equine surgeons of the second half of the 20th century. Raised in Daylesford, Pennsylvania, he received his VMD from the University of Pennsylvania (UP) in 1942. After several years in general practice, he joined the faculty of the UP as a surgeon involved with all large animal species. As one of the founding faculty of New Bolton Center, he gradually developed a strong clientele for cases involving general and orthopedic surgery of horses. Starting in the 1970s, he began to concentrate on upper respiratory surgery and became a preeminent leader in that …

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