Medicine and Health Sciences Commons^™

Health Promotion Practice And The Road Ahead: Addressing Enduring Gaps And Encouraging Greater Practice-To-Research Translation, Amanda Birnbaum, Mark D. Rivera

Department of Public Health Scholarship and Creative Works

A decade ago, Lancaster and Roe described four critical gaps (i.e., communications, accessibility, credibility, and expectations) between research and practice in health education and health promotion that formed the framework for this department. Despite considerable attention and some progress, these gaps persist and are barriers to interaction and translation between health promotion and health education research and practice. Looking to the next several years as the new Associate Editors for this department, we renew the department’s commitment toward addressing these enduring gaps around which we frame new questions and invite continued dialogue.

Median Lethal Dose, Antimalarial Activity, Phytochemical Screening And Radical Scavenging Of Methanolic Languas Galanga Rhizome Extract, Hesham Al-Mekhlafi

Hesham M Al-Mekhlafi

The methanolic extract of Languas galanga rhizomes was investigated for antimalarial activity against Plasmodium berghei (NK65) infections in mice. The median lethal dose was determined to ascertain the safety of the extract in ICR mice of both sexes. The antimalarial activities during early and established infections, as well as the prophylactic activity were evaluated. Phytochemical screening and radical scavenging activity of the extract were also investigated to elucidate the possible mechanism of the antimalarial properties. The acute oral toxicity (LD(50)) of Languas galanga extract in mice was established to be 4,998 mg/kg. The extract of Languas galanga rhizomes demonstrated significant …

End-Of-Life Care For Hospitalized Patients With Lung Cancer: Utilization Of A Palliative Care Service., Barbara Reville, M.S., Achpn, Marshal N Miller, B.S., Richard W Toner, M.S., Joanne Reifsnyder, Ph.D., Achpn

Department of Family & Community Medicine Faculty Papers

PURPOSE: High symptom burden and hospital mortality among patients with lung cancer argues for early palliative care intervention. Patient characteristics and discharge dispositions in hospitalized patients with lung cancer receiving usual care were compared to those referred to a new palliative care service.

METHODS: A retrospective database review of all lung cancer discharges receiving usual care (UC) and palliative care service (PCS) consultation was conducted. Demographics, length of stay, discharge disposition, and mortality were described and compared. Palliative Performance Scale scores were described according to discharge disposition in the PCS group. Disposition of all patients receiving either chemotherapy or surgery …

Transforming Chronic Care Education: A Longitudal Interprofessional Mentorship Curriculum, Lauren G. Collins, Md, Christine A. Arenson, Md, Christine Jerpbak, Md, Elena Umland, Pharmd, Stephen B. Kern, Phd, Otr/L, Faota, Leigh Ann Hewston, Pt, Med

Department of Family & Community Medicine Faculty Papers

Rationale:

Future state of academic medicine demands preparing students for collaborative, team-based practice.

Interprofessional education (IPE) is widely advocated as a key element to promote an effective redesigned healthcare system

Evidence and curricular resources describing effective IPE remain limited

Insulin Resistance In African-American And Caucasian Women: Differences In Lipotoxicity, Adipokines, And Gene Expression In Adipose Tissue And Muscle, Latasha M. Smith, Aiwei Yao-Borengasser, Tasha Starks, Mark Tripputi, Philip A. Kern, Neda Rasouli

Clinical and Translational Science Faculty Publications

Objectives: We tested whether African-American (AA) women are different from Caucasian women in regard to lipotoxicity, adipokines, and gene expression in adipose tissue and muscle.

Design: Insulin sensitivity (S_I), plasma adipocytokine levels, intramyocellular lipid (IMCL), and the expression of candidate genes in adipose tissue and muscle were measured in AA and Caucasian women.

Setting: This study was performed in an ambulatory general clinical research center.

Subjects: Subjects were healthy, nondiabetic AA and Caucasian women.

Interventions: There were no interventions.

Main Outcome Measures: Comparison of S_I, IMCL, plasma adiponectin, and the expression of candidate genes regulating adipogenesis, …

Matrix Metalloproteinase-9 Is Increased In Obese Subjects And Decreases In Response To Pioglitazone, Resat Unal, Aiwei Yao-Borengasser, Vijayalakshmi Varma, Neda Rasouli, Craig Labbate, Philip A. Kern, Gouri Ranganathan

Clinical and Translational Science Faculty Publications

Context: The study investigated the regulation of matrix metalloproteinases (MMP)-9 in obesity-associated insulin resistance in humans.

Objectives: The objectives of the investigation were to study MMP-9 regulation by insulin resistance and pioglitazone treatment in impaired glucose tolerant subjects using adipose tissue biopsies and study the mechanism of MMP-9 regulation by pioglitazone in adipocyte cultures.

Research Design: 86 nondiabetic, weight-stable subjects between 21 and 66 yr of age were recruited in a university hospital research center setting. All subjects underwent a sc adipose tissue incisional biopsy from the lower abdominal wall and insulin sensitivity testing using a frequently sampled iv glucose …

Opportunities And Obstacles To The Elimination Of Malaria From Peninsular Malaysia: Knowledge, Attitudes And Practices On Malaria Among Aboriginal And Rural Communities, Hesham Al-Mekhlafi

Hesham M Al-Mekhlafi

Background: Despite continuous efforts by the government and private sectors, malaria is still a public health problem in rural Peninsular Malaysia. This study investigated household knowledge, attitude and practices (KAP) regarding malaria in two malaria endemic communities, forest-aboriginal and rural communities, in the Lipis district of Pahang state, Malaysia. Methods: A descriptive cross-sectional study with a semi-structured questionnaire was carried out among 100 and 123 households from forest-aboriginal and rural areas, respectively. Results: Knowledge about malaria and its transmission is significantly higher among the rural participants than the aborigines (86.2% vs 76%, p < 0.01). However, use of medicinal plants and beliefs in witchcraft and sorcery in treating febrile diseases were significantly higher among the aboriginal population (p < 0.01). There were no significant differences between the two communities in terms of the knowledge about malaria symptoms, attitudes towards its severity and practices in preventive measures against malaria by using mosquito bed nets. However, the knowledge and practice of different preventive measures to combat malaria, such as insecticide and the elimination of breeding areas, was significantly higher among the rural population than the aborigines (p < 0.001). Conclusions: Both communities were aware of malaria as a disease, but knowledge, attitudes and practices were inadequate. Providing efficient health education to people residing in malaria endemic areas would improve their understanding about malaria prevention in order to bring about the elimination of malaria from the country.

Archetypal Energies, "Psychic Politics", And The Transformative Potential Of The Health Care Debate, Carroy U. Ferguson

Carroy U "Cuf" Ferguson, Ph.D.

In a previous message, I spoke of “Archetypal Energies, The Emergence of Obama As A Practical Idealist, and Global Transformation” (February/March 2009). I suggested that at issue is what I called “psychic politics for global transformation, nurtured by practical idealism and the Archetypal Energies.” To reiterate, I have described Archetypal Energies as Higher Vibrational Energies, operating deep within our individual and collective psyches, which have their own transcendent value, purpose, quality, and “voice” unique to the individual. We experience them as “creative urges” to move us toward our Highest Good or Optimal Realities. I use easily recognized terms to evoke …

Self Management Pilot Study On Women With Breast Cancer:, Siew Yim Loh Assoc Prof

Siew Yim Loh

Objective: With increasing survival rates, breast cancer is now considered a chronic condition necessitating innovative care to meet the long-term needs of survivors. This paper presents the findings of a pilot study on self-management for women diagnosed with breast cancer and their implications for Asian health care providers. Methods: A pre-test/ post-test pilot study was conducted to gain preliminary insights into program feasibility and barriers to participation, and to provide justification for a larger trial. Results: The study found the 4 week self management program feasible and acceptable, with a favourable trend in quality of life. The recruitment barriers ranged …

Minitipsheet4-2010, Lynn Shaw Dr.

Lynn Shaw

No abstract provided.

Work Transition Tips 2-2010 Support Groups And Health Professsionals Working Together, Lynn Shaw Dr.

Lynn Shaw

No abstract provided.

Ethnobotanical Study On Some Malaysian Anti-Malarial Plants: A Community Based Survey, Hesham Al-Mekhlafi

Hesham M Al-Mekhlafi

Ethnopharmacological relevance: Various plants species are used in the traditional medicine for the treatment of malaria. This is the first community based ethnobotanical study in Peninsular Malaysia. Aim of the study: To investigate the plants traditionally used in the treatment of malaria in Malaysia. Materials and methods: An ethnobotanical survey was carried out among 233 Aboriginal and rural households, and traditional healers in malaria endemic areas in Peninsular Malaysia. Data were collected using a pre-tested questionnaire. Results: Nineteen species belonging to 17 families were identified. Twelve plant species have not previously been documented for the treatment of malaria in Malaysia. …

Gene Therapy Rescues Cone Function In Congenital Achromatopsia, Andras Komaromy, John J. Alexander, Jessica S. Rowlan, Monique M. Garcia, Vincent Chiodo, Asli Kaya, Jacqueline C. Tanaka, Gregory M. Acland, William W. Hauswirth, Gustavo D. Aguirre

Gustavo D. Aguirre, VMD, PhD

Work Transition Tips 3-2010 Developing A Network Of Supports, Lynn Shaw Dr.

Lynn Shaw

No abstract provided.

Work Transition Tips 1-2010, Lynn Shaw Dr.

Lynn Shaw

No abstract provided.

Physical Activity And Women With Breast Cancer: Insights From The Expert Patients., Siew Yim Loh Assoc Prof

Assoc Prof Dr Siew Yim Loh

Introduction: Physical activity participation amongst cancer survivors is low. This potent modifiable host factor has been disregarded in the cancer treatment plan for decades, despite its role in cancer control. The purpose of this study was to explore perception of physical activity among women with breast cancer. Methods: Focus group with purposive sampling methods were conducted on women at different cancer trajectory - ie. completed treatment (n=6) and undergoing treatment (n=8). The taped discussions were transcribed verbatim and analyzed using a grounded theory approach. Concepts were identified as unique or shared between the two groups, and ordered into subcategories. Results …