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Full-Text Articles in Medicine and Health Sciences

Contributions Of Community Organizations To Personal Outcomes For People With Intellectual And Developmental Disabilities: A Study Of Special Olympics Program Participation, Seb M. Prohn, Parthenia Dinora, Kayla Diggs Brody Jul 2023

Contributions Of Community Organizations To Personal Outcomes For People With Intellectual And Developmental Disabilities: A Study Of Special Olympics Program Participation, Seb M. Prohn, Parthenia Dinora, Kayla Diggs Brody

Developmental Disabilities Network Journal

Community organizations can enhance the intellectual and developmental disability (I/DD) service system’s ability to improve the health, wellness, and participation of people with I/DD. This study added an item about Special Olympics (SO) participation to the 2019-2020 National Core Indicators In-Person Survey to predict active SO participation and to determine whether personal outcomes differed for SO participants. Results of a multinomial logistic regression showed that people who were younger or who did not require mobility aids were more likely to participate in SO. Compared with people who never or formerly participated in SO, current SO athletes had better personal outcomes. …


Incorporating Poi As A Therapeutic Modality For Preschool Aged Children In The Care Clinic, Danielle Zirkle Jul 2023

Incorporating Poi As A Therapeutic Modality For Preschool Aged Children In The Care Clinic, Danielle Zirkle

Department of Occupational Therapy Entry-Level Capstone Projects

No abstract provided.


Risk Management Perceptions And Preventive Practices Of Athletic Directors From Naia Schools, Yan Gioseffi Jul 2023

Risk Management Perceptions And Preventive Practices Of Athletic Directors From Naia Schools, Yan Gioseffi

Health, Exercise, and Sports Sciences ETDs

The increase in the number of incidents associated with sports has led to the rise of litigation, and physical, emotional, and financial damage to stakeholders. Collegiate athletic directors (ADs) have the duty to keep their programs safe.

This study aimed to explore and understand the practices, perceptions, and experiences of ADs from National Association of Intercollegiate Athletics (NAIA) institutions regarding preventive risk management. As risk management is significantly new in the sporting industry, an exploratory study using a qualitative design, grounded in narrative inquiry was conducted using the D.I.M. Process as a guide to collect data from 10 NAIA ADs …


Can I Count On You? Social Support, Depression And Suicide Risk, Christiana Silva, Christopher Mcgovern, Stephanie Gomez, Eleanor Beale, James Overholser Jul 2023

Can I Count On You? Social Support, Depression And Suicide Risk, Christiana Silva, Christopher Mcgovern, Stephanie Gomez, Eleanor Beale, James Overholser

Student Scholarship

Objectives: Interpersonal factors play an important role in the etiology and treatment of depression. Social support derives from compassionate words and helpful actions provided by family, friends or a significant other. The present study was designed to examine various sources of social support as they relate to the severity of depressive symptoms, hopelessness and suicide risk in adult psychiatric outpatients. Method: Participants were recruited through mental health clinics at a veteran's affairs medical centre. A total of 96 depressed patients were assessed using a diagnostic interview and self-report measures of depression severity, hopelessness and social support. Among these depressed adults, …


Intimate Partner Violence Screening In The Emergency Department, Rebecca Stuerman Jul 2023

Intimate Partner Violence Screening In The Emergency Department, Rebecca Stuerman

Dissertations

Problem: Intimate partner violence [IPV] is a public health concern that affects one in three women worldwide. IPV can be addressed through identification and early intervention with minimal risk to the patient. The emergency department is an important setting for screening given the frequency with which people who experience abuse may present with IPV-related injuries and other related concerns (depression, suicidality, etc.). Successfully implementing a validated tool for screening and providing early access to resources and referrals may help to mitigate the longterm negative impacts of IPV. The need for increased staff education was a major barrier to screening for …


Investigating The Longitudinal Relationship Between Social Motivation And Depression In Autistic Adults, Robyn H. Himelstein Jul 2023

Investigating The Longitudinal Relationship Between Social Motivation And Depression In Autistic Adults, Robyn H. Himelstein

Theses and Dissertations

Autism affects individuals across the lifespan, yet there tends to be limited research and services for autistic adults. This is especially concerning given that autistic adults have high mental health needs, with depression being one of the most common and clinically significant co-occurring conditions. We explored the longitudinal relationships between social motivation, social access (i.e., having opportunities for meaningful social interactions), loneliness, and depression in N=303 autistic adults ages 18-65. Participants completed online surveys about social behavior and wellbeing three times over 3–4 months. We hypothesized that an interaction between higher social motivation and lower social access at Time 1 …


The Role Of English Language Courses In Media Colleges In Providing Their Graduates With Labor Market Skills: An Applied Study On Graduates Of Middle East University, Mazen Al-Fedawi Jul 2023

The Role Of English Language Courses In Media Colleges In Providing Their Graduates With Labor Market Skills: An Applied Study On Graduates Of Middle East University, Mazen Al-Fedawi

Middle East Journal of Communication Studies

The study aimed to identify the degree of contribution of English language courses in providing graduates with the necessary skills by achieving the specifications of the graduate of the Faculty of Mass Communication required in the labor market, and the degree of their acquisition of the professional skills required in the labor market. It also aimed to explore whether there are differences between the acquisition of labor market skills among graduates of mass media faculties due to variables, type of specialization, number of years of work, and gender. The study achieved these objectives through an applied survey study on an …


Skills That Help Employ Media Graduates In The Labor Market From The Point Of View Of Practicing Media Professionals., Mahmoud Al-Rajabi Jul 2023

Skills That Help Employ Media Graduates In The Labor Market From The Point Of View Of Practicing Media Professionals., Mahmoud Al-Rajabi

Middle East Journal of Communication Studies

The study aimed to reveal the most important skills that help to employ graduates of media faculties in the labor market from the point of view of media practitioners. The study used two approaches, the qualitative methodology and the inductive approach, by conducting in-depth interviews with seventeen media practitioners in Jordan, and the sample was taken in an intentional way. The results of the study showed that the skills that a media graduate should possess are both pure media skills and other skills such as research skills, critical thinking skills, content building skills, interpersonal skills, Arabic and media language skills, …


The Role Of Practical Courses In The Faculty Of Media At The Middle East University In Providing Graduates With Labor Market Skills, Ahmad Oreqat, Ramez Abuhasirah Jul 2023

The Role Of Practical Courses In The Faculty Of Media At The Middle East University In Providing Graduates With Labor Market Skills, Ahmad Oreqat, Ramez Abuhasirah

Middle East Journal of Communication Studies

The study aimed at identifying the role of the practical courses at the Faculty of Media at the Middle East University in providing its graduates with skills in the media labor market. The study adopted the media audience survey method. A questionnaire was distributed to an available sample of (48) graduates of the Faculty of Media at Middle East University who practice the media profession. The results showed that practical study courses’ contribution to providing graduates with the required specifications in the labor market came to a high degree, as the most important of these specifications were: “decent and acceptable …


The Academic Training In Media Faculties And Its Implications For Professional Practice: A Field Study On Media Practitioners In Jordanian Media Institutions, Ramez Abuhasirah Jul 2023

The Academic Training In Media Faculties And Its Implications For Professional Practice: A Field Study On Media Practitioners In Jordanian Media Institutions, Ramez Abuhasirah

Middle East Journal of Communication Studies

This study aimed at identifying the reflection of media academic education on professional practice. The study adopted the audience survey method. A questionnaire was distributed to an available sample of (102) professionals in Jordanian media institutions who hold a media certificate. The study’s results showed that the primary academic education of media professionals was represented in: “the predominance of theoretical aspects over practical aspects in academic courses,” with a mean of (4.30). In contrast, the media skills and practical professional training of professionals in Jordan’s media institutions were represented in: “the reflection of media training on the professional performance of …


The Phenomenon Of Information Flow From Traditional And New Media About The Corona Pandemic From The Perspective Of Newly Graduated Media Professionals In Yemen, Mansour Al-Muntasir Jul 2023

The Phenomenon Of Information Flow From Traditional And New Media About The Corona Pandemic From The Perspective Of Newly Graduated Media Professionals In Yemen, Mansour Al-Muntasir

Middle East Journal of Communication Studies

This study aims to explore the external limits of the Corona pandemic in all traditional and new media, which paid attention to this event in a way that the media had not seen before, relying on citizens' participation in the production of news in social media. This study also aims to find out how newly graduated journalists interact with the event on both professional and personal levels, especially with the spread of misinformation and fake news about the Corona virus. The researchers have adopted the qualitative method to obtain deep information from the sample selected by the study, as it …


The Role Of Radio And Television Programmes In Providing Drug Information From The Perspectives Of The Jordanian Public And Pharmaceutical Sector Employees, Obadah Sa’Ad, Omar Al Rashdan, Hanan Al-Shiekh Jul 2023

The Role Of Radio And Television Programmes In Providing Drug Information From The Perspectives Of The Jordanian Public And Pharmaceutical Sector Employees, Obadah Sa’Ad, Omar Al Rashdan, Hanan Al-Shiekh

Middle East Journal of Communication Studies

This study aimed to identify the role of radio and television programmes in providing drug information to the Jordanian society. The study adopted the descriptive analytical approach, and two special questionnaires were developed for the study. The study sample consisted of (287) employees from the pharmaceutical sector (pharmacists, doctors), and (389) members of the Jordanian public who visited Hamzah and Al-Bashir Hospitals in Amman, Jordan. The results of the study concluded that the role of radio and television programmes in providing drug information to the Jordanian society from the viewpoint of the public came to a medium degree, and that …


The Reality Of Media Training In Jordanian Media Institutions From The View Point Of Journalists - A Field Study, Kamel Khurshid Murad, Saddam Al-Mashagbah Jul 2023

The Reality Of Media Training In Jordanian Media Institutions From The View Point Of Journalists - A Field Study, Kamel Khurshid Murad, Saddam Al-Mashagbah

Middle East Journal of Communication Studies

The article aimed to identify the reality of media training in Jordanian media institutions from the point of view of journalists in Jordan. It adopted a descriptive approach using a questionnaire distributed to a simple random sample of (66) journalists in the Radio and Television Corporation, Petra Agency, daily newspapers, some electronic news websites, the Journalists Syndicate and some satellite channels. The results revealed that 43.9% of the media institutions have departments for training, and 51.5% are interested in holding training courses at a medium rate. The results also showed that 53.0% of the sample describe the percentage of learning …


The Impact Of Negative Online Rumors On The Attitudes Of The Palestinian Audience Towards The Liberation Of The Six Prisoners: A Content Analysis Of Facebook Pages, Suhair Al Rjoub, Saed Shaheen Jul 2023

The Impact Of Negative Online Rumors On The Attitudes Of The Palestinian Audience Towards The Liberation Of The Six Prisoners: A Content Analysis Of Facebook Pages, Suhair Al Rjoub, Saed Shaheen

Middle East Journal of Communication Studies

This research aims to identify the topics covered by Facebook pages regarding the issue of the six prisoners’ liberation. It deals with the negative impact of rumors on the Palestinian public’s attitudes towards the issue of the six prisoners’ liberation on Facebook through analyzing the content of the pages. In this study, the research used the content analysis tool; the sample of the study included five pages that dealt with the issue of the six prisoners who liberated themselves through a tunnel under Gilboa prison. The research deployed the theory of social responsibility and relied on the “descriptive survey” to …


The Effectiveness Of Media Curricula In Sudanese Universities In Light Of The Challenges And Requirements Of The Labor Market In The Era Of Digital Media From Media Faculties’ Perspectives, Lamia Salah Al Deen Mohammad Ibrahim Jul 2023

The Effectiveness Of Media Curricula In Sudanese Universities In Light Of The Challenges And Requirements Of The Labor Market In The Era Of Digital Media From Media Faculties’ Perspectives, Lamia Salah Al Deen Mohammad Ibrahim

Middle East Journal of Communication Studies

This study aimed to identify the effectiveness of the media curricula in Sudanese universities regarding the challenges and the requirements of the labor market in the era of digital media. The researcher used the descriptive analytical approach; an electronic questionnaire form was designed as a tool for data collection. It was distributed to a simple random sample consisting of (40) individuals, representing (45%) of the total study population represented by (95) professors. The study concludes with a number of findings, most importantly are: the degree of effectiveness of the media curricula in Sudanese universities in light of the challenges and …


The Effectiveness Of Interactive Video In Developing Animation Production Skills For Educational Technology Students At Middle East University, Fadi Abdulraheem Odah Jul 2023

The Effectiveness Of Interactive Video In Developing Animation Production Skills For Educational Technology Students At Middle East University, Fadi Abdulraheem Odah

Middle East Journal of Communication Studies

This study deals with the effectiveness of interactive video in developing animation production skills among Educational Technology students at Middle East University. The researcher used semi-experimental mothod, where the research sample consisted of (40) students from Educational Technology students at the Faculty of Educational Siences, Middle East University. The sample consisted of two equal groups: a control group of (20) male and female students that were taught in the usual way at laboratories, and an experemental group of (20) students that were taught through interactive vide. The research tools consisted of an observation card to measure the performance. The results …


The Who’S Interest In Its Communication Messages On (Covid-19) Pandemic Via Facebook And Twitter Platforms, Rana Mezher Khalid, Layla Ahmad Jarrar Jul 2023

The Who’S Interest In Its Communication Messages On (Covid-19) Pandemic Via Facebook And Twitter Platforms, Rana Mezher Khalid, Layla Ahmad Jarrar

Middle East Journal of Communication Studies

The study aims to identify the degree of interest of the World Health Organization (WHO) through social networks in dealing with the Covid-19 pandemic on Facebook and Twitter platforms. The theory of media frameworks was implemented, and the content analysis was used as a tool for quantitative and qualitative analysis of the communicative messages of the organization. A deliberate sample was selected, which included all the messages of the World Health Organization during the period from the beginning of the disease until its declaration as a global pandemic, that is: during the period from 30/12/2019 – 11/3/2020, and this time …


Job Satisfaction Among Female Media Professionals In Palestine And The Obstacles They Face In Practicing Their Work, Mohammad Ahmad Injas, Izzat Mohammad Hijab Jul 2023

Job Satisfaction Among Female Media Professionals In Palestine And The Obstacles They Face In Practicing Their Work, Mohammad Ahmad Injas, Izzat Mohammad Hijab

Middle East Journal of Communication Studies

The study aimed to identify the climates in which Palestinian female media work, identify the obstacles that female media face, and identify their degree of job satisfaction. The study used the descriptive survey method, and the study adopted a questionnaire as a tool for collecting data related to the topic of the research, which was distributed to a random sample of (180) female media professionals out of (206) female media workers, according to the Palestine Journalists Syndicate record for the year 2020. The results of the study showed that the media profession affects the familial and family stability of female …


How The Palestinian Cause Has Been Framed In The Jordanian Opinion Articles, Hani Ahmad Fayez Al-Badri Jul 2023

How The Palestinian Cause Has Been Framed In The Jordanian Opinion Articles, Hani Ahmad Fayez Al-Badri

Middle East Journal of Communication Studies

This study aims to identify the presentation of the Palestinian cause in Jordanian opinion articles published on online news sites representing daily newspapers. In addition to monitoring the topics and issues that have been highlighted, and comparing the similarities and differences between the sample newspapers in discussing this cause. The study uses the media survey methodology and the comparative approach in order to obtain required data and information, and compare the analysis results of the opinion articles in both Alghad and Addustour newspapers. The study population is represented in the opinion articles published on online news sites that represent daily …


The Role Of Jordanian Mass Media In Facing The Rumors From Communication Practitioner’S Perspective: Survey Study, Rami Basem Yousef Haddad, Kamel Khurshid Murad Jul 2023

The Role Of Jordanian Mass Media In Facing The Rumors From Communication Practitioner’S Perspective: Survey Study, Rami Basem Yousef Haddad, Kamel Khurshid Murad

Middle East Journal of Communication Studies

The study aimed to define role of the Jordanian media in facing rumors as seen by communicators, to identify the most common rumors and the motives behind them. The study adopted the survey method with a questionnaire as a tool for collecting data. The study The study aimed to define role of the Jordanian media in facing rumors as seen by communicators, to identify the most common rumors and the motives behind them. The study adopted the survey method with a questionnaire as a tool for collecting data. The study population consisted of 397 communicators working in official Jordanian media …


Political Participation In Jordan In Light Of The Royal Discussion Papers, Sahar Mohammad Al Tarawneh, Rema Lutfi Abu Hmidan Jul 2023

Political Participation In Jordan In Light Of The Royal Discussion Papers, Sahar Mohammad Al Tarawneh, Rema Lutfi Abu Hmidan

Middle East Journal of Communication Studies

Effective political participation plays a key role in promoting good democratic governance and the rule of law in order to achieve transparency and the principle of accountability, which contribute mainly to the process of political, economic and social development. This study aims to define political participation and its application forms, and to identify democratic practices and the elements of political participation in Jordan in light of the political reform process and the royal discussion papers. The study also tackles the role of the means of communication and media as a major factor in this process and discusses the opportunities of …


Is The Public Aware Of Water Quality Monitoring And Safety Notifications On Beaches?, Asli Aslan, Jeffery A. Jones, Dziyana Nazaruk, Sibel Zeki Jul 2023

Is The Public Aware Of Water Quality Monitoring And Safety Notifications On Beaches?, Asli Aslan, Jeffery A. Jones, Dziyana Nazaruk, Sibel Zeki

Journal of the Georgia Public Health Association

Recreational water-related activities have important public health benefits, however, pollution at beaches may have serious health risks. Although there is a substantial amount of research and policies in place at federal and state levels, oftentimes these efforts may not be well translated to the public. This paper evaluates the effectiveness of routine water quality monitoring and warning systems in Georgia, USA. A survey was conducted among 238 beachgoers in Georgia, asking about awareness of water quality monitoring and warning signs for beach advisories. Surveys were collected directly at beaches as well as through an online questionnaire. Results show that more …


Older Adults With A History Of Psychiatric Conditions Experience More Cognitive Decline Than Older Adults Without This History, Maria T. Brown, Miriam Mutambudzi Jul 2023

Older Adults With A History Of Psychiatric Conditions Experience More Cognitive Decline Than Older Adults Without This History, Maria T. Brown, Miriam Mutambudzi

Population Health Research Brief Series

Having psychiatric conditions (such as bipolar disorder, schizophrenia, and major depressive disorder) throughout one’s life can lead to faster rates of cognitive decline as one ages. This data slice explores the associations between psychiatric history and cognitive function among U.S. White, Black, and Hispanic adults ages 65 and older from 1995-2014. Findings demonstrate that having a history of psychiatric problems is related to lower cognitive functioning and a faster rate of cognitive decline for all three groups, but Black and Hispanic adults experience steeper declines compared with White adults.


The Medical Institutional Repositories In Libraries (Mirl) Symposium: A Blueprint Designed In Response To A Community Of Practice Need., Brenda Fay, Lisa M Buda, Anthony J Dellureficio, Sara Hoover, Ramune K Kubilius, Steven J Moore, Lisa A Palmer Jul 2023

The Medical Institutional Repositories In Libraries (Mirl) Symposium: A Blueprint Designed In Response To A Community Of Practice Need., Brenda Fay, Lisa M Buda, Anthony J Dellureficio, Sara Hoover, Ramune K Kubilius, Steven J Moore, Lisa A Palmer

Himmelfarb Library Faculty Publications

BACKGROUND: Health sciences libraries in medical schools, academic health centers, health care networks, and hospitals have established institutional repositories (IRs) to showcase their research achievements, increase visibility, expand the reach of institutional scholarship, and disseminate unique content. Newer roles for IRs include publishing open access journals, tracking researcher productivity, and serving as repositories for data sharing. Many repository managers oversee their IR with limited assistance from others at their institution. Therefore, IR practitioners find it valuable to network and learn from colleagues at other institutions.

CASE PRESENTATION: This case report describes the genesis and implementation of a new initiative specifically …


Who Puts The "Support" In Supportive Housing? The Impact Of Housing Staff On Resident's Well-Being, And The Potential Moderating Role Of Self-Determination, Kenna Estell Dickard Jul 2023

Who Puts The "Support" In Supportive Housing? The Impact Of Housing Staff On Resident's Well-Being, And The Potential Moderating Role Of Self-Determination, Kenna Estell Dickard

Dissertations and Theses

The provision of residential and community-based services for individuals with serious mental illness (SMI) has become increasingly important following the deinstitutionalization movement. Much of the existing research on supportive housing focuses on housing outcomes rather than exploring how the program helps its residents thrive in the broader community. This study draws upon data collected from 176 people with SMI residing in 16 supportive housing locations in Portland, Oregon. Analyses employed an ecological approach, exploring how housing staff support relates to residents' well-being at three levels of analysis: loneliness (interpersonal level), residential satisfaction (housing and neighborhood level), and sense of community …


Unmasking Structural Racism In U.S. Medical Education: Advancing Equity For Underrepresented Medical Students, Daryl O. Traylor, Eboni E. Anderson, Destiney Kirby, Asia Nichole Hodges, Brianna Clark, Stephen Sinatra Jr. Jul 2023

Unmasking Structural Racism In U.S. Medical Education: Advancing Equity For Underrepresented Medical Students, Daryl O. Traylor, Eboni E. Anderson, Destiney Kirby, Asia Nichole Hodges, Brianna Clark, Stephen Sinatra Jr.

Journal of Social, Behavioral, and Health Sciences

The COVID pandemic cast a harsh light on the structural and systemic health inequalities that exist in American society and in U.S. medical education. Black and Brown communities were disproportionately affected, and the pandemic highlighted the need for a diverse physician and healthcare workforce. Both the lack of equitable, high-quality healthcare in underrepresented communities and the obstacles that students who are underrepresented in medicine (URiM) experience in medical school are direct consequences of the structural racism that flourishes in U.S. medical schools and healthcare institutions. In this article, we explain structural racism and how it has manifested itself in medical …


Differentials And Predictors Of Food Insecurity Among Federally Qualified Health Center Target Populations In Philadelphia: A Cross-Sectional Study, Galicano Kai Inguito, Brandon Joa, James Gardner, Eric N Fung, Laura Layer, Karen Fritz Jul 2023

Differentials And Predictors Of Food Insecurity Among Federally Qualified Health Center Target Populations In Philadelphia: A Cross-Sectional Study, Galicano Kai Inguito, Brandon Joa, James Gardner, Eric N Fung, Laura Layer, Karen Fritz

Department of Medicine Faculty Papers

BACKGROUND: Over the past decade, the prevalence of food insecurity declined in the United States but curiously climbed in Philadelphia, Pennsylvania, a sizable metropolitan area where many households experience food insecurity and are dependent on programs like SNAP. Therefore, we aimed to determine the burden of food insecurity among populations near Philadelphia Federally Qualified Health Center (FQHC) clinic sites.

METHODS: This cross-sectional study was conducted in North Philadelphia, a populous and impoverished section of Philadelphia with many zip codes reporting 30-45% or more of the population below the federal poverty line. Students and clinicians affiliated with a local FQHC conducted …


Using Predictive Validity To Compare Associations Between Brain Damage And Behavior, John F Magnotti, Jaclyn S Patterson, Tatiana T Schnur Jul 2023

Using Predictive Validity To Compare Associations Between Brain Damage And Behavior, John F Magnotti, Jaclyn S Patterson, Tatiana T Schnur

Faculty, Staff and Student Publications

Lesion-behavior mapping (LBM) provides a statistical map of the association between voxel-wise brain damage and individual differences in behavior. To understand whether two behaviors are mediated by damage to distinct regions, researchers often compare LBM weight outputs by either the Overlap method or the Correlation method. However, these methods lack statistical criteria to determine whether two LBM are distinct versus the same and are disconnected from a major goal of LBMs: predicting behavior from brain damage. Without such criteria, researchers may draw conclusions from numeric differences between LBMs that are irrelevant to predicting behavior. We developed and validated a predictive …


Affect Variability And Physical Health: The Moderating Role Of Mean Affect, Brooke N. Jenkins, Lydia Q. Ong, Hee Youn (Helen) Lee, Anthony D. Ong, Julia K. Boehm Jul 2023

Affect Variability And Physical Health: The Moderating Role Of Mean Affect, Brooke N. Jenkins, Lydia Q. Ong, Hee Youn (Helen) Lee, Anthony D. Ong, Julia K. Boehm

Psychology Faculty Articles and Research

Research has only begun to explore how affect variability relates to physical health and has typically not assessed long-term associations nor considered the moderating role of mean affect. Therefore, we used data from the Midlife in the United States Study waves 2 (N = 1512) and 3 (N = 1499) to test how affect variability predicted concurrent and long-term physical health while also testing the moderating role of mean affect. Results indicated that greater negative affect variability was associated concurrently with a greater number of chronic conditions (p = .03) and longitudinally with worse self-rated physical health (p …


Evaluating Approaches For Constructing Polygenic Risk Scores For Prostate Cancer In Men Of African And European Ancestry, Burcu F Darst, Jiayi Shen, Ravi K Madduri, Alexis A Rodriguez, Yukai Xiao, Xin Sheng, Edward J Saunders, Tokhir Dadaev, Mark N Brook, Thomas J Hoffmann, Kenneth Muir, Peggy Wan, Loic Le Marchand, Lynne Wilkens, Ying Wang, Johanna Schleutker, Robert J Macinnis, Cezary Cybulski, David E Neal, Børge G Nordestgaard, Sune F Nielsen, Jyotsna Batra, Judith A Clements, Australian Prostate Cancer Bioresource, Henrik Grönberg, Nora Pashayan, Ruth C Travis, Jong Y Park, Demetrius Albanes, Stephanie Weinstein, Lorelei A Mucci, David J Hunter, Kathryn L Penney, Catherine M Tangen, Robert J Hamilton, Marie-Élise Parent, Janet L Stanford, Stella Koutros, Alicja Wolk, Karina D Sørensen, William J Blot, Edward D Yeboah, James E Mensah, Yong-Jie Lu, Daniel J Schaid, Stephen N Thibodeau, Catharine M West, Christiane Maier, Adam S Kibel, Géraldine Cancel-Tassin, Florence Menegaux, Esther M John, Eli Marie Grindedal, Kay-Tee Khaw, Sue A Ingles, Ana Vega, Barry S Rosenstein, Manuel R Teixeira, Nc-La Pcap Investigators, Manolis Kogevinas, Lisa Cannon-Albright, Chad Huff, Luc Multigner, Radka Kaneva, Robin J Leach, Hermann Brenner, Ann W Hsing, Rick A Kittles, Adam B Murphy, Christopher J Logothetis, Susan L Neuhausen, William B Isaacs, Barbara Nemesure, Anselm J Hennis, John Carpten, Hardev Pandha, Kim De Ruyck, Jianfeng Xu, Azad Razack, Soo-Hwang Teo, Canary Pass Investigators, Lisa F Newcomb, Jay H Fowke, Christine Neslund-Dudas, Benjamin A Rybicki, Marija Gamulin, Nawaid Usmani, Frank Claessens, Manuela Gago-Dominguez, Jose Esteban Castelao, Paul A Townsend, Dana C Crawford, Gyorgy Petrovics, Graham Casey, Monique J Roobol, Jennifer F Hu, Sonja I Berndt, Stephen K Van Den Eeden, Douglas F Easton, Stephen J Chanock, Michael B Cook, Fredrik Wiklund, John S Witte, Rosalind A Eeles, Zsofia Kote-Jarai, Stephen Watya, John M Gaziano, Amy C Justice, David V Conti, Christopher A Haiman Jul 2023

Evaluating Approaches For Constructing Polygenic Risk Scores For Prostate Cancer In Men Of African And European Ancestry, Burcu F Darst, Jiayi Shen, Ravi K Madduri, Alexis A Rodriguez, Yukai Xiao, Xin Sheng, Edward J Saunders, Tokhir Dadaev, Mark N Brook, Thomas J Hoffmann, Kenneth Muir, Peggy Wan, Loic Le Marchand, Lynne Wilkens, Ying Wang, Johanna Schleutker, Robert J Macinnis, Cezary Cybulski, David E Neal, Børge G Nordestgaard, Sune F Nielsen, Jyotsna Batra, Judith A Clements, Australian Prostate Cancer Bioresource, Henrik Grönberg, Nora Pashayan, Ruth C Travis, Jong Y Park, Demetrius Albanes, Stephanie Weinstein, Lorelei A Mucci, David J Hunter, Kathryn L Penney, Catherine M Tangen, Robert J Hamilton, Marie-Élise Parent, Janet L Stanford, Stella Koutros, Alicja Wolk, Karina D Sørensen, William J Blot, Edward D Yeboah, James E Mensah, Yong-Jie Lu, Daniel J Schaid, Stephen N Thibodeau, Catharine M West, Christiane Maier, Adam S Kibel, Géraldine Cancel-Tassin, Florence Menegaux, Esther M John, Eli Marie Grindedal, Kay-Tee Khaw, Sue A Ingles, Ana Vega, Barry S Rosenstein, Manuel R Teixeira, Nc-La Pcap Investigators, Manolis Kogevinas, Lisa Cannon-Albright, Chad Huff, Luc Multigner, Radka Kaneva, Robin J Leach, Hermann Brenner, Ann W Hsing, Rick A Kittles, Adam B Murphy, Christopher J Logothetis, Susan L Neuhausen, William B Isaacs, Barbara Nemesure, Anselm J Hennis, John Carpten, Hardev Pandha, Kim De Ruyck, Jianfeng Xu, Azad Razack, Soo-Hwang Teo, Canary Pass Investigators, Lisa F Newcomb, Jay H Fowke, Christine Neslund-Dudas, Benjamin A Rybicki, Marija Gamulin, Nawaid Usmani, Frank Claessens, Manuela Gago-Dominguez, Jose Esteban Castelao, Paul A Townsend, Dana C Crawford, Gyorgy Petrovics, Graham Casey, Monique J Roobol, Jennifer F Hu, Sonja I Berndt, Stephen K Van Den Eeden, Douglas F Easton, Stephen J Chanock, Michael B Cook, Fredrik Wiklund, John S Witte, Rosalind A Eeles, Zsofia Kote-Jarai, Stephen Watya, John M Gaziano, Amy C Justice, David V Conti, Christopher A Haiman

Faculty, Staff and Student Publications

Genome-wide polygenic risk scores (GW-PRSs) have been reported to have better predictive ability than PRSs based on genome-wide significance thresholds across numerous traits. We compared the predictive ability of several GW-PRS approaches to a recently developed PRS of 269 established prostate cancer-risk variants from multi-ancestry GWASs and fine-mapping studies (PRS269). GW-PRS models were trained with a large and diverse prostate cancer GWAS of 107,247 cases and 127,006 controls that we previously used to develop the multi-ancestry PRS269. Resulting models were independently tested in 1,586 cases and 1,047 controls of African ancestry from the California Uganda Study and 8,046 cases and …