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Articles 4531 - 4560 of 33704
Full-Text Articles in Medicine and Health Sciences
“I Had To Go There For My Own Safety” Negotiations Of Access And Autonomy Among Dc Birth Settings, Elizabeth Avery Borgmann
“I Had To Go There For My Own Safety” Negotiations Of Access And Autonomy Among Dc Birth Settings, Elizabeth Avery Borgmann
Geography Undergraduate Senior Theses
Childbirth experiences are shaped by spatial context. This study considers the relationships between access to, selection of, and experiences with labor and delivery care among Black birthing people in Washington, DC. Informed by Reproductive Justice and reproductive geographies frameworks, I employ a mixed methods GIS design that integrates mapping of potential spatial access with qualitative analysis of community members’ lived experiences. On the quantitative side, nearest-neighbor and 2-step floating catchment area analyses reveal an east-west gradient of potential spatial access to labor and delivery wards, with low access concentrated in predominantly Black and low-income census tracts of Wards 5, 7, …
Spatial Targeting Of Irrigation Development And Water Resource Management To Mitigate Vector-Borne Disease, April Frake, Brad Peter, Grivin Chipula, Joseph Messina
Spatial Targeting Of Irrigation Development And Water Resource Management To Mitigate Vector-Borne Disease, April Frake, Brad Peter, Grivin Chipula, Joseph Messina
Geosciences Faculty Publications and Presentations
Scaling irrigated agriculture is a global strategy to mitigate food insecurity concerns. While expanding irrigated agriculture is critical to meeting food production demands, it is important to consider how these land use and land cover changes (LULCC) may alter the water resources of landscapes and impact the spatiotemporal epidemiology of disease. Here, a generalizable method is presented to inform irrigation development decision-making aimed at increasing crop production through irrigation while simultaneously mitigating malaria risk to surrounding communities. Changes to the spatiotemporal patterns of malaria vector (Anopheles gambiae s.s.) suitability, driven by irrigated agricultural expansion, are presented for Malawi's rainy and …
Equity In Access For Veterans In The Va Community Care Program, Baligh R. Yehia, Said A. Ibrahim
Equity In Access For Veterans In The Va Community Care Program, Baligh R. Yehia, Said A. Ibrahim
Department of Medicine Faculty Papers
No abstract provided.
Pediatric Obesity In The United States: Age–Period–Cohort Analysis, Ashley W. Kranjac, Dinko Kranjac, Roxanne I. Aguilera
Pediatric Obesity In The United States: Age–Period–Cohort Analysis, Ashley W. Kranjac, Dinko Kranjac, Roxanne I. Aguilera
Sociology Faculty Articles and Research
The rates of obesity among American children aged 2–5 years has reached a historic high. It is crucial to identify the putative sources of population-level increases in obesity prevalence among preschool-aged children because early childhood is a critical window for obesity prevention and thus reduction of future incidence. We used the National Health and Nutrition Examination Survey data and hierarchical age–period–cohort analysis to examine lifecycle (i.e., age), historical (i.e., period), and generational (i.e., cohort) distribution of age- and sex-specific body mass index z-scores (zBMI) among 2–5-year-olds in the U.S. from 1999 to 2018. Our current findings indicate that period effects, …
Pm25, Vegetation Density, And Childhood Cancer: A Case-Control Registry-Based Study From Texas 1995–2011, Lindsay A Williams, David Haynes, Jeannette M Sample, Zhanni Lu, Ali Hossaini, Laura A Mcguinn, Thanh T Hoang, Philip J Lupo, Michael E Scheurer
Pm25, Vegetation Density, And Childhood Cancer: A Case-Control Registry-Based Study From Texas 1995–2011, Lindsay A Williams, David Haynes, Jeannette M Sample, Zhanni Lu, Ali Hossaini, Laura A Mcguinn, Thanh T Hoang, Philip J Lupo, Michael E Scheurer
Center for Medical Ethics and Health Policy Staff Publications
Background: Air pollution is positively associated with some childhood cancers, whereas greenness is inversely associated with some adult cancers. The interplay between air pollution and greenness in childhood cancer etiology is unclear. We estimated the association between early-life air pollution and greenness exposure and childhood cancer in Texas (1995 to 2011).
Methods: We included 6101 cancer cases and 109 762 controls (aged 0 to 16 years). We linked residential birth address to census tract annual average fine particulate matter < 2.5 µg/m³ (PM2.5) and Normalized Difference Vegetation Index (NDVI). We estimated odds ratios (ORs) and 95% confidence intervals (CIs) between PM2.5/NDVI interquartile range increases and cancer. We assessed statistical interaction between PM2.5 and NDVI (likelihood ratio tests).
Results: Increasing residential early-life PM2.5 exposure was associated with all childhood cancers (OR = 1.10, 95% CI = 1.06 to 1.15), …
An Exploratory Analysis Of Sociodemographic Factors Associated With Physical Functional Impairment In Icu Survivors, Megan A. Watson, Marie Sandi, Johanna Bixby, Grace Perry, Patrick J. Offner, Ellen L. Burnham, Sarah E. Jolley
An Exploratory Analysis Of Sociodemographic Factors Associated With Physical Functional Impairment In Icu Survivors, Megan A. Watson, Marie Sandi, Johanna Bixby, Grace Perry, Patrick J. Offner, Ellen L. Burnham, Sarah E. Jolley
School of Medicine Faculty Publications
IMPORTANCE: Physical functional impairment is one of three components of postintensive care syndrome (PICS) that affects up to 60% of ICU survivors. OBJECTIVES: To explore the prevalence of objective physical functional impairment among a diverse cohort of ICU survivors, both at discharge and longitudinally, and to highlight sociodemographic factors that might be associated with the presence of objective physical functional impairment. DESIGN, SETTING, AND PARTICIPANTS: This was a secondary analysis of 37 patients admitted to the ICU in New Orleans, Louisiana, and Denver, Colorado between 2016 and 2019 who survived with longitudinal follow-up data. MAIN OUTCOMES AND MEASURES: Our primary …
The Role Of Digital Citizenship Using Modern Communication And Media Tools In Enhancing Social Responsibility Among Students Of The Middle East University, Ramzi Mubarak Al Tarawneh, Sahar Mohammad Al Tarawneh
The Role Of Digital Citizenship Using Modern Communication And Media Tools In Enhancing Social Responsibility Among Students Of The Middle East University, Ramzi Mubarak Al Tarawneh, Sahar Mohammad Al Tarawneh
Middle East Journal of Communication Studies
The study aims to explore the role of digital citizenship using modern communication and media tools in enhancing social responsibility among MEU students. A descriptive-analytical approach was used. The study employed a simple random sampling method, with a sample size of 421 students. The findings indicated a statistically significant impact of digital citizenship using modern communication and media tools on social responsibility in its various dimensions. Both digital citizenship using modern communication and media tools and social responsibility were practiced at a high level. Furthermore, a strong correlation was found between digital citizenship using modern communication and media tools and …
The Cost Of Long-Term Care In The Mountain West, 2023, Madison Dwyer, Freddy Nie, Annie Vong, Caitlin J. Saladino, William E. Brown Jr.
The Cost Of Long-Term Care In The Mountain West, 2023, Madison Dwyer, Freddy Nie, Annie Vong, Caitlin J. Saladino, William E. Brown Jr.
Health
This fact sheet examines data on the cost of long-term care for the Mountain West states of Arizona, Colorado, Nevada, New Mexico, and Utah from the Genworth “Cost of Care Survey.” Data on long-term care includes home health care, adult day health care facilities, licensed assisted living facilities, and certified and licensed nursing homes.
06.03.2024 Orsp Connect, Liz Williamson
06.03.2024 Orsp Connect, Liz Williamson
ORED Newsletter
Center for Population Studies, NSF Postdoc Berg, Quinn Appointed to HEPAP, Smitherman migraine research
Speech-Language Pathology In China: An Overview, Guanyu Wei
Speech-Language Pathology In China: An Overview, Guanyu Wei
Student Scholarship
Purpose: China is a middle-income developing country that is aging rapidly. Speech-language pathology is a developing field in China. The article aims to provide a brief overview of the current status of speech-language pathology in China.
Method: This article presents the authors' viewpoint, bolstered by insights from nine speech-language pathologists (SLPs) in China. To enrich the depth of the discussion on achievements and challenges within the Chinese speech-language pathology field, the authors also conducted a review of relevant articles in Standard Chinese–based databases.
Result and Discussion: The authors have delineated both the major achievements and barriers in …
Developing An Ethics And Policy Framework For Psychedelic Clinical Care: A Consensus Statement, Amy L Mcguire, I Glenn Cohen, Dominic Sisti, Matthew Baggott, Yuria Celidwen, Nese Devenot, Sabrina Gracias, Charles Grob, Ifetayo Harvey, Brent Kious, Mason Marks, Michael Mithoefer, Elizabeth Nielson, Dost Öngür, Alexandra Pallas, Andrew Peterson, Eduardo E Schenberg, Paul Summergrad, Brett Waters, Monnica T Williams, David B Yaden
Developing An Ethics And Policy Framework For Psychedelic Clinical Care: A Consensus Statement, Amy L Mcguire, I Glenn Cohen, Dominic Sisti, Matthew Baggott, Yuria Celidwen, Nese Devenot, Sabrina Gracias, Charles Grob, Ifetayo Harvey, Brent Kious, Mason Marks, Michael Mithoefer, Elizabeth Nielson, Dost Öngür, Alexandra Pallas, Andrew Peterson, Eduardo E Schenberg, Paul Summergrad, Brett Waters, Monnica T Williams, David B Yaden
Center for Medical Ethics and Health Policy Staff Publications
Importance: As government agencies around the globe contemplate approval of the first psychedelic medicines, many questions remain about their ethical integration into mainstream medical practice.
Objective: To identify key ethics and policy issues related to the eventual integration of psychedelic therapies into clinical practice.
Evidence review: From June 9 to 12, 2023, 27 individuals representing the perspectives of clinicians, researchers, Indigenous groups, industry, philanthropy, veterans, retreat facilitators, training programs, and bioethicists convened at the Banbury Center at Cold Spring Harbor Laboratory. Prior to the meeting, attendees submitted key ethics and policy issues for psychedelic medicine. Responses were categorized into 6 …
Building Trust: The Role Of Place-Based Consciousness In Vaccine Hesitancy, Ramsey W. Ash
Building Trust: The Role Of Place-Based Consciousness In Vaccine Hesitancy, Ramsey W. Ash
Quantitative Social Science Undergraduate Senior Theses
Vaccine hesitancy poses a threat to public health initiatives of the 21st century. Following a stark divide in the rural/urban COVID-19 vaccine uptake and harsh disparities between these areas in COVID-19 moralities and morbidities, further understanding of the drivers of vaccine hesitancy are needed. This study makes use of the framework of place-based consciousness (PBC), pioneered by scholars of rural political science, such as Katherine Cramer, to explore this phenomenon as a mechanism by which to understand vaccine hesitancy. To examine this, an experimental survey was distributed to 300 Americans (150 rural and 150 urban) that inquired about their PBC, …
Graphic Medicine As Library Outreach, Chanda Briggs
Graphic Medicine As Library Outreach, Chanda Briggs
Gleeson Library Faculty and Staff Research and Scholarship
One of the most compelling aspects of graphic novels is the ability to connect to the emotions of the reader through visual storytelling. Understanding the challenges another person faces or realizing that one’s own challenges are not unique can boost a reader’s empathy as well as their sense of belonging.
The low-lift-high-impact nature of graphic medicine is perfect for awareness campaigns as well as critical scholarship. It makes praxis practical and disarms a reader’s defenses to experience the vulnerability of being fully human. Graphic novels meet students where they are. The high circulation statistics speak for themselves and through graphic …
Plagiarism, Richard Alweis, Nagesh Jadhav
Plagiarism, Richard Alweis, Nagesh Jadhav
Rochester Regional Health authored publications and proceedings
Learning objectives:
- Plagiarism overview
- A special case: large language models (LLM) and academic writing
Small Island Risks: Research Reflections For Disaster Anthropologists And Climate Ethnographers, Crystal A. Felima
Small Island Risks: Research Reflections For Disaster Anthropologists And Climate Ethnographers, Crystal A. Felima
UK CARES Faculty Publications
Disasters and climate-related events, including tropical storms, droughts, coastal erosion, and ocean acidification, threaten small island nations. Given the urgency of reducing disaster risks and the effects of climate change on vulnerable populations, this reflection essay pursues three objectives. First, it highlights the role of anthropology, ethnography, and multi-sited research in exploring disaster impacts, climate crises, and public policy in island communities. It then highlights national planning and inter-regional activities to build awareness of various risk reduction efforts by island nations and multi-governmental organizations. This article concludes with discussion prompts to engage researchers, scholars, students, and practitioners studying and working …
Associations Between Disordered Eating Behaviour And Sexual Behaviour Amongst Emerging Adults Attending A Tertiary Education Institution In Coastal Kenya, Stevenson Chea, Adama Kazienga, Eunice Oyugi, Isaac Menza, Carophine Nasambu, Fauz Ibrahim, Osman Abdullahi, Amin Hassan, Amina Abubakar, Kristien Michielsen
Associations Between Disordered Eating Behaviour And Sexual Behaviour Amongst Emerging Adults Attending A Tertiary Education Institution In Coastal Kenya, Stevenson Chea, Adama Kazienga, Eunice Oyugi, Isaac Menza, Carophine Nasambu, Fauz Ibrahim, Osman Abdullahi, Amin Hassan, Amina Abubakar, Kristien Michielsen
Institute for Human Development, East Africa
Background Sexual behavior (SB) is a well-documented pathway to HIV acquisition in emerging adults and remains common amongst African emerging adults. Previous research in high-income countries indicates a correlation between disordered eating behavior (DEB) and engaging in sexual behaviors. We aimed to describe the relationship between DEB and SB amongst emerging adults attending a tertiary educational institution at the Kenyan Coast.
Methods We applied a cross-sectional design nested in a young adults’ cohort study. Eligibility included sexually active emerging adults aged 18–24 years. Three DEBs (emotional, restrained and external eating) were assessed using the Dutch Eating Behavior Questionnaire and analysed …
Flanker Task Performance In Young And Older Adults: A Behavioral And Erp Study, Fatima Medrano
Flanker Task Performance In Young And Older Adults: A Behavioral And Erp Study, Fatima Medrano
Dissertations, Theses, and Capstone Projects
Research suggests that as we get older, executive function abilities decline (Hasher & Zacks, 1988; Salthouse, 1996). One affected ability is that of inhibitory control, which aids in monitoring our responses to non-target stimuli or information. Current research on inhibition reveals inconsistencies across studies. Monitoring brain responses during the Flanker (used to measure inhibitory control) task may add valuable insight into the processes underlying group differences behaviorally, by studying the N200 and P300 event-related potentials which have been associated with inhibitory control processes. This study investigated whether there are differences between older and younger adults in inhibitory control and whether …
A Word From The Writing Team (June 2024), Pam Walter, Mfa
A Word From The Writing Team (June 2024), Pam Walter, Mfa
A Word From the Writing Team (Newsletter)
This issue includes:
- Publication Spotlight
- Sign up for the 16th Annual Jefferson Faculty Days: June 5 & 6
- Don’t Forget Summer Writing Time!
- Jefferson Held a Symposium on AI And Research Integrity – And Recorded It
- Jefferson's AI Library Guide is Available on the Library Website
- The OPWPC Canvas Page Offers Helpful Tools
- Scott Memorial Library Archive Renovations are Done—Come See!
Family Fragments: Pressure And Proximity In First-Episode Psychosis, Cassandra B. Seltman
Family Fragments: Pressure And Proximity In First-Episode Psychosis, Cassandra B. Seltman
Dissertations, Theses, and Capstone Projects
This study explores the value of assuming a position that decenters the identified patient in families with a member with schizophrenia. Instead, a systemic view of the family is taken, as subject to pressures from without and within, and utilizing observable processes for the management and discharge of tension. It attempts the difficult balance of thinking dynamically without sacrificing scientific rigor, considering the social without discounting the biological, and exploring the functionality of the family without collapsing into blame, reductive cause-and-effect thinking, and the search to prioritize one true origin.
When treating family members as discrete units around an identified …
Cognitive And Neuroscientific Perspectives Of Healthy Ageing, Jon B. Prince, Helen L. Davis, Jane Tan, Katrina Muller-Townsend, Shaun Markovic, David M. G. Lewis, Brianne Hastie, Matthew B. Thompson, Peter D. Drummond, Hakuei Fujiyama, Hamid R. Sohrabi
Cognitive And Neuroscientific Perspectives Of Healthy Ageing, Jon B. Prince, Helen L. Davis, Jane Tan, Katrina Muller-Townsend, Shaun Markovic, David M. G. Lewis, Brianne Hastie, Matthew B. Thompson, Peter D. Drummond, Hakuei Fujiyama, Hamid R. Sohrabi
Research outputs 2022 to 2026
With dementia incidence projected to escalate significantly within the next 25 years, the United Nations declared 2021–2030 the Decade of Healthy Ageing, emphasising cognition as a crucial element. As a leading discipline in cognition and ageing research, psychology is well-equipped to offer insights for translational research, clinical practice, and policy-making. In this comprehensive review, we discuss the current state of knowledge on age-related changes in cognition and psychological health. We discuss cognitive changes during ageing, including (a) heterogeneity in the rate, trajectory, and characteristics of decline experienced by older adults, (b) the role of cognitive reserve in age-related cognitive decline, …
Voices Of Experience: Lay Perspectives On Severe Maternal Morbidity In Appalachia, Anna Hansen, Cassidy Carter, Nancy Schoenberg, Carrie B. Oser
Voices Of Experience: Lay Perspectives On Severe Maternal Morbidity In Appalachia, Anna Hansen, Cassidy Carter, Nancy Schoenberg, Carrie B. Oser
UK CARES Faculty Publications
No abstract provided.
Two Cases Of Pigmented Basal Cell Carcinoma In African American Patients, Angelique Ruml, Joan K Fernandez, Ibeth Caceres, Nisha Ramani, Ida Orengo, Theodore Rosen
Two Cases Of Pigmented Basal Cell Carcinoma In African American Patients, Angelique Ruml, Joan K Fernandez, Ibeth Caceres, Nisha Ramani, Ida Orengo, Theodore Rosen
Faculty, Staff and Students Publications
Basal cell carcinoma (BCC) is the most common cutaneous malignancy, comprising approximately 80% of non-melanoma skin cancers. There are numerous subtypes, including pigmented basal cell carcinoma (pBCC), a rare clinical and histological variant. Skin cancers in African American patients, although rare, still do occur. BCC is an uncommon neoplasm in this population, but when it does occur, pigmentation is present in more than 50% of tumors compared with only 5% to 6% of BCCs in Caucasians. This report presents two cases of histologically verified pBCC in African American patients from dermatology clinics at the Veterans Affairs Hospital located in the …
Dietary Probiotic Supplement Attenuates Methamphetamine-Induced Conditioned Place Preference In Female Sprague-Dawley Rats, Kristen Powell
Dietary Probiotic Supplement Attenuates Methamphetamine-Induced Conditioned Place Preference In Female Sprague-Dawley Rats, Kristen Powell
Masters Theses
Substance use disorders (SUD) represent a global public health crisis with limited effective treatment options. Recent findings implicate the gut microbiome and gut/brain axis in the pathophysiology of SUDs. Several preclinical studies have established that psychostimulants alter gut microbiome composition, but no published studies have assessed behavioral effects of dietary probiotic supplements on drug-induced behavioral changes. This study utilized rodent conditioned place preference (CPP) as a behavioral index of conditioned drug reward to determine if a dietary probiotic supplement alters the behavioral effects of (+)-methamphetamine (METH). Fifty-four adult female Sprague-Dawley rats were randomly assigned to receive either a standard rodent …
Strengthening U.S. Jail Systems’ Response To Infectious Diseases: An Evaluation Of The Covid-19 Pandemic, Erinn Bacchus
Strengthening U.S. Jail Systems’ Response To Infectious Diseases: An Evaluation Of The Covid-19 Pandemic, Erinn Bacchus
Dissertations and Theses
Jails across the United States were struck with increased infections and deaths during the COVID-19 pandemic. Studies have shown the structural make up of jails, lack of preparedness plans, and overcrowding contributed to health risks and poor health outcomes both inside jails and local communities. Yet little research has been dedicated to strengthening jail responses to infectious disease outbreaks spanning prevention measures, data collection, and reentry planning. Gaps include information on the (1) myriad infectious disease mitigation strategies used in jails and adherence to CDC prevention guidelines, (2) development of a standardized epidemiologic surveillance system, and (3) experiences working at …
Accessible Real-Time Eye-Gaze Tracking For Neurocognitive Health Assessments, A Multimodal Web-Based Approach, Daniel C. Tisdale
Accessible Real-Time Eye-Gaze Tracking For Neurocognitive Health Assessments, A Multimodal Web-Based Approach, Daniel C. Tisdale
Master's Theses
We introduce a novel integration of real-time, predictive eye-gaze tracking models into a multimodal dialogue system tailored for remote health assessments. This system is designed to be highly accessible requiring only a conventional webcam for video input along with minimal cursor interaction and utilizes engaging gaze-based tasks that can be performed directly in a web browser. We have crafted dynamic subsystems that capture high-quality data efficiently and maintain quality through instances of user attrition and incomplete calls. Additionally, these subsystems are designed with the foresight to allow for future re-analysis using improved predictive models, as well as enable the creation …
Exploring How Factors Affecting Exercise Adherence May Inform Strategies To Increase Adherence In General And Depressed Populations: A Literature Review, Henry D. Link
University Honors Theses
Background: Exercise is associated with numerous physical and mental health benefits; however, many people struggle to exercise a sufficient amount and thus do not reap the benefits. Exercise is recognized as an effective treatment for depression with few risks. Professionals must understand the factors affecting exercise adherence to assist individuals of different backgrounds with adhering to exercise over the long term and to avoid common pitfalls that could hinder an individual’s progress.
Objective: This literature review aimed to identify factors affecting exercise adherence and to explore how those factors could inform strategies to increase exercise adherence among depressed …
Measurement Invariance Of The Pandemic Anxiety Inventory In Different Demographic Groups, Irvin Sam Schonfeld, Tasmyn Prytherch, Mark Cropley, Jay Verkuilen, Renzo Bianchi
Measurement Invariance Of The Pandemic Anxiety Inventory In Different Demographic Groups, Irvin Sam Schonfeld, Tasmyn Prytherch, Mark Cropley, Jay Verkuilen, Renzo Bianchi
Publications and Research
Background The Pandemic Anxiety Inventory (PAI) was developed in the context of the COVID-19 pandemic. Its content allows it to assess anxiety in connection to any pandemic. Previous research has demonstrated the instrument’s reliability and validity. An important question for clinicians and researchers, however, remains open: Does the PAI have similar meaning for members of different demographic groups? The finding of measurement invariance would allow clinicians and researchers to comparatively assess pandemic-related anxiety across demographic groups, including favored and disfavored groups.
Methods We conducted a multi-group confirmatory factor analysis to assess the measurement invariance of the PAI using data obtained …
Impact Of Librarian-Mediated Literature Search Services, Frances Chu
Impact Of Librarian-Mediated Literature Search Services, Frances Chu
2024 Swedish Learning and Celebration Day
No abstract provided.
The Relationship Between Healthcare Access And Change In Health-Related Quality-Of-Life Among The General Population Of Five Countries During The Covid-19 Pandemic, Nadja Alexandrov, Emily Stella Scott, Mathieu F. Janssen, Erica I. Lubetkin, John N. Yfantopoulos, Gouke J. Bonsel, Juanita A. Haagsma
The Relationship Between Healthcare Access And Change In Health-Related Quality-Of-Life Among The General Population Of Five Countries During The Covid-19 Pandemic, Nadja Alexandrov, Emily Stella Scott, Mathieu F. Janssen, Erica I. Lubetkin, John N. Yfantopoulos, Gouke J. Bonsel, Juanita A. Haagsma
Publications and Research
Purpose To determine whether (1) healthcare access at onset of the pandemic and (2) age, gender, socioeconomic status (SES), and pre-existing health status were associated with change in health-related quality-of-life (HRQoL) during the COVID-19 pandemic. The study includes a general population sample of five countries.
Methods An online questionnaire was administered to respondents from Greece, Italy, the Netherlands, the UK, and the US at the onset of the COVID-19 pandemic between April 22nd and May 5th of 2020, and 1 year later between May 23rd and June 29th of 2021. The questionnaire included questions on demographic background, health status, and …
Associations Between Longer Leukocyte Telomere Length And Increased Lung Cancer Risk Among Never Smokers In Urban China, Jason Y Y Wong, Xiao-Ou Shu, Wei Hu, Batel Blechter, Jianxin Shi, Kevin Wang, Richard Cawthon, Qiuyin Cai, Gong Yang, Mohammad L Rahman, Bu-Tian Ji, Yutang Gao, Wei Zheng, Nathaniel Rothman, Qing Lan
Associations Between Longer Leukocyte Telomere Length And Increased Lung Cancer Risk Among Never Smokers In Urban China, Jason Y Y Wong, Xiao-Ou Shu, Wei Hu, Batel Blechter, Jianxin Shi, Kevin Wang, Richard Cawthon, Qiuyin Cai, Gong Yang, Mohammad L Rahman, Bu-Tian Ji, Yutang Gao, Wei Zheng, Nathaniel Rothman, Qing Lan
Faculty, Staff and Student Publications
BACKGROUND: The complex relationship between measured leukocyte telomere length (LTL), genetically predicted LTL (gTL), and carcinogenesis is exemplified by lung cancer. We previously reported associations between longer pre-diagnostic LTL, gTL, and increased lung cancer risk among European and East Asian populations. However, we had limited statistical power to examine the associations among never smokers by gender and histology.
METHODS: To investigate further, we conducted nested case-control analyses on an expanded sample of never smokers from the prospective Shanghai Women's Health Studies (798 cases and 792 controls) and Shanghai Men's Health Studies (161 cases and 162 controls). We broke the case-control …