Medicine and Health Sciences Commons^™

Evaluations Of Exercise Intolerance With Cardiopulmonary Exercise Tests In A 24-Year-Old Young Male With Obesity With Tetrahydrobiopterin Deficiency: A Case Report, Chun-Yu Chen, Shin-Tsu Chang, Ko-Long Lin, Mu-Hsun Wu

Rehabilitation Practice and Science

Phenylketonuria (PKU) is a rare amino acid metabolism genetic disorder. Tetrahydrobiopterin (BH4) metabolism defects cause variant PKU. BH4 coenzyme deficiency disables phenylalanine metabolism into tyrosine, causing brain damage and intellectual impairment. Patients follow a low-phenylalanine diet for life, increasing the risk of obesity, hypertension, and metabolic syndrome. A 24-year-old male patient with BH4 deficiency underwent a pulmonary function test and cardiopulmonary exercise test (CPET). Forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) were within normal values, with an 80.68% ratio. The 20-watt bicycle exercise test indicated moderate functional impairment (27.3 ml/kg/min of peak oxygen intake). The …

The Effects Of Implementing An Early Childhood Education Health And Wellness Program In Underserved Elementary Schools In Las Vegas On Student Mentors And Elementary Staff: Anatomy Academy, Alexa Blazek, Amber Berumen Baker, Kevin Chan Shum, Alexander Young

UNLV Theses, Dissertations, Professional Papers, and Capstones

Academy (AA) is a seven/eight-week program implemented by select University of Nevada, Las Vegas Doctorate of Physical Therapy (DPT) students to promote health and wellness at a Title I elementary school and help bridge the health education gap that underserved youth populations may be facing. We aimed to assess and improve the overall satisfaction of both the faculty members at the elementary school and the physical therapy students who participated in the program, while enhancing the health education of 5th grade students. Our aim was centered on stakeholders (elementary school administrators) and student mentors (DPT students) having the desire to …

Evaluation Of The Train 2 Run Program At The Joplin Va Community Based Outpatient Clinic (Cboc), Jenifer Webb

Doctor of Nursing Practice Scholarly Project

THE EVALUATION OF A TRAIN 2 RUN PROGRAM AT THE JOPLIN VA CLINIC

An Abstract of the Scholarly Project

by Jenifer Webb, MSN, RN, FNP-C

The purpose of this project is to evaluate the effectiveness and satisfaction levels of participants in the Train 2 Run program that was started at the Joplin VA in Joplin, MO. The program was from May 3, 2022, to October 8, 2022, for a total of 5 months. The participants for this study were selected from the patients, family members, and staff who participated in the Train 2 Run program for a minimum of six …

Anatomy Academy Service-Learning Project: Attacking The Epidemic Of Childhood Obesity, Kelsey Kjer, Rosedaveia Howell, Brennan Kitchen, Francesca Schutte

UNLV Theses, Dissertations, Professional Papers, and Capstones

The World Health Organization has classified childhood obesity as one of the most serious public health concerns in the world. Obesity is known to have detrimental health consequences and be a risk for comorbidities. On top of the consequences of obesity already seen in young children at school, a lack of health education interventions in many elementary schools remains a significant health disparity. Anatomy Academy (AA) is a seven-week curriculum designed to educate children about their bodies and the importance of gaining and maintaining a healthy lifestyle. The purpose of this service-learning project was to educate elementary school students in …

New-R Intervention For Clients With Severe Mental Illness And Obesity: Grant Writing For Implementation Funds Supporting Occupational Therapy Interventions, Kaitlyn Hoffman

UNLV Theses, Dissertations, Professional Papers, and Capstones

Increasing numbers of people suffer from obesity and severe mental illness co-morbidly. If these conditions remain untreated, they can harm an individual's health and well-being. Unfortunately, there are very few programs currently available that target both management and improvement of these conditions simultaneously. Even so, despite the lack of programming options, it must be noted that the NEW-R program strives to reach those goals, although there hasn't been an abundance of literature supporting the effectiveness of this program. This poses a concern for occupational therapy practitioners who hope to assist their clients in managing these conditions as occupational therapy treatments …

Pre–Post Intervention Exploring Cognitive Function And Relationships With Weight Loss, Intervention Adherence And Dropout, Amanda N. Szabo-Reed, Laura E. Martin, Cary R. Savage, Richard A. Washburn, Joseph E. Donnelley

Center for Brain, Biology, and Behavior: Faculty and Staff Publications

Objective: To evaluate the association between baseline cognitive function, intervention dropout, adherence and 3-month weight loss (WL) when controlling for confounding demographic variables.

Methods: 107 (Mage = 40.9 yrs.), BMI in the overweight and obese range (BMI = 35.6 kg/m2), men (N = 17) and women (N = 90) completed a 3-month WL intervention. Participants attended weekly behavioral sessions, comply with a reduced calorie diet, and complete 100 min of physical activity (PA)/wk. Cognitive function tasks at baseline included Flanker (attention), Stroop (executive control) and working memory, demographics, body weight and cardiovascular fitness were assessed at baseline. Session attendance, adherence …

Accuracy Of Body Mass Index In Categorizing Weight Status In Children With Intellectual And Developmental Disabilities, Michele Polfuss, Bethany Forseth, Dale A. Schoeller, Chiang-Ching Huang, Andrea Moosreiner, Paula E. Papanek, Kathleen J. Sawin, Kimberley Zvara, Linda Bandini

Exercise Science Faculty Research and Publications

PURPOSE:

To identify the accuracy of Body Mass Index (BMI) to categorize body weight in a sample of children with spina bifida and Down syndrome as compared to typically developing peers.

METHODS:

A secondary analysis of 32 children with spina bifida, Down syndrome or no chronic illness. A calculated BMI was plotted on the Centers for Disease Control and Prevention age- and sex-specific BMI growth charts to determine each child’s weight status. Percentage of body fat, obtained by labeled water, was plotted on two different body fat percentile reference curves, one derived from a whole body measure (DXA) of body …

A Comparison Of Activity Participation Between Children With And Without Asthma, Jacqueline R. Jezioro, Sharon A. Gutman, Stephanie Lovinsky-Desir, Virginia Rauh, Frederica P. Perera, Rachel L. Miller

The Open Journal of Occupational Therapy

Background: Asthma affects approximately 6 million children in the United States and can greatly impact quality of life and occupational engagement. Although occupational therapists are well-equipped to address participation limitations, insufficient evidence exists to support the role of occupational therapists in asthma treatment.

Method: The purpose of this study was to further understand the occupational limitations experienced by children with asthma. We also explored a dual diagnosis of asthma and obesity. The participants included children with (n = 84) and without (n = 63) asthma living in New York City. The Child Behavior Checklist, Youth Self Report, Brief …

The Β3-Adrenergic Receptor Agonist Mirabegron Improves Glucose Homeostasis In Obese Humans, Brian S. Finlin, Hasiyet Memetimin, Beibei Zhu, Amy L. Confides, Hemendra J. Vekaria, Riham H. El Khouli, Zachary R. Johnson, Philip M. Westgate, Jianzhong Chen, Andrew J. Morris, Patrick G. Sullivan, Esther E. Dupont-Versteegden, Philip A. Kern

Internal Medicine Faculty Publications

BACKGROUND. Beige adipose tissue is associated with improved glucose homeostasis in mice. Adipose tissue contains β3-adrenergic receptors (β3-ARs), and this study was intended to determine whether the treatment of obese, insulin-resistant humans with the β3-AR agonist mirabegron, which stimulates beige adipose formation in subcutaneous white adipose tissue (SC WAT), would induce other beneficial changes in fat and muscle and improve metabolic homeostasis.

METHODS. Before and after β3-AR agonist treatment, oral glucose tolerance tests and euglycemic clamps were performed, and histochemical analysis and gene expression profiling were performed on fat and muscle biopsies. PET-CT scans quantified brown adipose tissue volume and …

Modeling Interactions Between Brain Function, Diet Adherence Behaviors, And Weight Loss Success, Amanda N. Szabo-Reed, Laura E. Martin, Jinxiang Hu, Hung-Wen Yeh, Joshua Powell, Rebecca J. Lepping, Trisha M. Patrician, Florance J. Breslin, Joseph E. Donnelly, Cary R. Savage

Center for Brain, Biology, and Behavior: Faculty and Staff Publications

Summary

Introduction: Obesity is linked to altered activation in reward and control brain cir-cuitry; however, the associated brain activity related to successful or unsuccessful weight loss (WL) is unclear.

Methods: Adults with obesity (N = 75) completed a baseline functional magnetic res-onance imaging (fMRI) scan before entering a WL intervention (ie,3-month diet and physical activity [PA] program). We conducted an exploratory analysis to identify the contributions of baseline brain activation, adherence behavior patterns, and the asso-ciated connections to WL at the conclusion of a 3-month WL intervention. Food cue-reactivity brain regions were functionally identified using fMRI to index brain activation …

Energy Cost Of Land And Shallow Water Walking In Females Who Are Overweight And Obese, Jacquelyn N. Zera, Elizabeth F. Nagle, Bethany B. Gibbs, John P. Abt, John M. Jakicic

International Journal of Aquatic Research and Education

Nineteen overweight or obese females completed three 10-minute experimental trials including a self-selected pace shallow water walking trial, a matched heart rate response land walking trial, and a self-selected pace land walking trial. Energy expenditure (kcal·min^-1)was computed from expired gases assessed via indirect calorimetry. Results showed energy expenditure was lower (p= 0.046) during shallow water walking (6.46 ± 1.38 kcal·min^-1) compared to matched heart rate response land walking trial (7.26 ± 1.29 kcal·min^-1), with no significant difference in between shallow water and self-selected pace land walking (6.92 ± 1.61 kcal·min^-1). …

Wavelet-Based Analysis Of Physical Activity And Sleep Movement Data From Wearable Sensors Among Obese Adults, Rahul Soangra, Vennila Krishnan

Physical Therapy Faculty Articles and Research

Decreased physical activity in obese individuals is associated with a prevalence of cardiovascular and metabolic disorders. Physicians usually recommend that obese individuals change their lifestyle, specifically changes in diet, exercise, and other physical activities for obesity management. Therefore, understanding physical activity and sleep behavior is an essential aspect of obesity management. With innovations in mobile and electronic health care technologies, wearable inertial sensors have been used extensively over the past decade for monitoring human activities. Despite significant progress with the wearable inertial sensing technology, there is a knowledge gap among researchers regarding how to analyze longitudinal multi-day inertial sensor data …

The Effect Of Standing-Desks On Productivity In Obese Populations, Lindsey Wright

EXSI 432/532: Research Methods in Exercise Science: Research Proposal Posters

This study was designed to understand how the use of a standing desk would affect the cognitive function and motor skills of obese subjects.

Total Energy Expenditure And Body Composition Of Children With Developmental Disabilities, Michele L. Polfuss, Kathleen J. Sawin, Paula E. Papanek, Linda Bandini, Bethany Forseth, Andrea Moosreiner, Kimberley Zvara, Dale A. Schoeller

Exercise Science Faculty Research and Publications

Background

Obesity prevalence is increased in children with developmental disabilities, specifically in children with spina bifida and Down syndrome. Energy expenditure, a critical aspect of weight management, has been extensively studied in the typically developing population, but not adequately studied in children with developmental disabilities.

Objective

Determine energy expenditure, fat-free mass and body fat percentile and the impact of these findings on recommended caloric intake in children with spina bifida and Down syndrome.

Methods/Measures

This pilot study included 36 children, 18 with spina bifida, 9 with Down syndrome and 9 typically developing children. Half of the children with spina bifida …

Dynamical Properties Of Postural Control In Obese Community-Dwelling Older Adults, Christopher W. Frames, Rahul Soangra, Thurmon Lockhart, John Lach, Dong Sam Ha, Karen A. Roberto, Abraham Lieberman

Physical Therapy Faculty Articles and Research

Postural control is a key aspect in preventing falls. The aim of this study was to determine if obesity affected balance in community-dwelling older adults and serve as an indicator of fall risk. The participants were randomly assigned to receive a comprehensive geriatric assessment followed by a longitudinal assessment of their fall history. The standing postural balance was measured for 98 participants with a Body Mass Index (BMI) ranging from 18 to 63 kg/m2, using a force plate and an inertial measurement unit affixed at the sternum. Participants’ fall history was recorded over 2 years and participants with at least …

Resistance Training-Induced Gains In Muscle Strength, Body Composition, And Functional Capacity Are Attenuated In Elderly Women With Sarcopenic Obesity, Alessandro De Oliveira Silva, Maurílio Tiradentes Dutra, Wilson Max Almeida Monteiro De Moraes, Silvana Schwerz Funghetto, Darlan Lopes De Farias, Paulo Henrique Fernandes Dos Santos, Denis Cesar Leite Vieira, Dahan Da Cunha Nascimento, Vânia Silva Macedo Orsano, Brad J. Schoenfeld, Jonato Prestes

Publications and Research

Objectives: The purpose of this study was to compare the effects of resistance training (RT) on body composition, muscle strength, and functional capacity in elderly women with and without sarcopenic obesity (SO).

Methods: A total of 49 women (aged $60 years) were divided in two groups: without SO (non-SO, n=41) and with SO (n=8). Both groups performed a periodized RT program consisting of two weekly sessions for 16 weeks. All measures were assessed at baseline and postintervention, including anthropometry and body composition (dual-energy X-ray absorptiometry), muscle strength (one repetition maximum) for chest press and 45° leg press, and functional capacity …

Association Between Hispanic Parents' Attitudes And Knowledge Regarding Obesity And Their Children's Body Mass Index: Implications For The Development Of Obesity, Renee Starr

Theses and Dissertations

According to the World Health Organization (WHO, 2017), more than 1.9 billion adults age 18 and older are overweight and over 650 million are obese. Data collected through the Centers for Disease Control indicates the prevalence of U.S. adults who are overweight and obese is estimated at 36.5% and the national childhood obesity rate is more than 12.7 million (17%), with approximately one in six school-aged children reaching the obesity level (Ogden, Carroll, Fryar, & Flegal, 2015). Hispanic children have the highest levels of obesity among all racial/ethnic groups (21.9%) and obesity rates are especially prevalent among impoverished Hispanics residing …

The Kinetic Chain Of Pelvic Pain, Jennifer Flenorl, Anne H. Boddy

St. Augustine, Fall 2017

The purpose of this case study is to examine the effectiveness of traditional pelvic floor rehabilitation and functional activity training in reducing and eliminating pelvic pain in the obese, adolescent female population.

The Role Of Occupational Therapy In Community-Based Programming: Addressing Childhood Health Promotion, Julie D. Kugel, Heather Javherian-Dysinger, Liane Hewitt

The Open Journal of Occupational Therapy

Background: Obesity and poor health habits impact youth’s health and occupational participation. Occupational therapy’s role in preventing and treating obesity continues to emerge in the research literature. This article explores the impact of a community-based program emphasizing health and wellness for female youth.

Methods: Five girls 11 to 13 years of age participated in the healthy occupations program. Before and after the program, the participants engaged in an individual semi-structured interview and completed the Canadian Occupational Performance Measure and the CATCH Kids Club Questionnaire. The youth participated in a focus group midprogram.

Results: The participants were receptive …

Obesity Is Associated With More Disability At Presentation And After Treatment In Low Back Pain But Not In Neck Pain: Findings From The Oioc Registry, Maria M. Wertli, Ulrike Held, Marco Campello, Shira Schecter Weiner

The School of Health Sciences Publications and Research

Background: The influence on the treatment response in patients with low back pain (LBP) and neck pain (NP) is unknown. The aim of the study was to investigate the influence of body weight in patients with low back pain (LBP) and neck pain (NP) on baseline and end of treatment disability.

Methods: Cross-sectional analysis of baseline factors. Longitudinal analysis of prospectively collected patient information at an outpatient physical therapy registry (data from June 2010 to December 2012). WHO-BMI classification was used: underweight, lean, overweight, obesity class I, obesity class II and III. The influence of body weight and …

The Effect Of Bmi On Oxygen Saturation At Rest And During Mild Walking, Jerrold S. Petrofsky, Michael S. Laymon, Iman Akef Khowailed, Stacy Fisher, Andrew Mills

College of Health & Human Services (TUN) Publications and Research

Eighty one subjects were examined for the relationship between BMI, body fat, arterial oxygen saturation and arterial PO2 with the subjects at rest and after 5 minutes of walking on a treadmill ergometer at 3 mph at a 3% grade. They had BMIs between 19 and 50. All subjects were free of cardiovascular disease and had normal blood pressure making it safe for them to participate in mild exercise. They were all able to walk for at least 10 minutes without cardiovascular complications and were not taking any medications that altered the autonomic nervous system. The age was between 22 …

The Effects Of Obesity On Human Ambulation: A Lower Joint Analysis, Laura Gilbert

Senior Honors Theses

The effects of obesity on the body are complex and numerous especially when combining the effects on an already multi-faceted and multi-systems action such as human ambulation. This study summarizes a wide range of research performed, which investigated the effects of obesity on human ambulation. The effects are broken down into categories including osteoarthritis, replacement surgery, center of mass, stepping cycle, muscular activation, and specifics of the hip, knee and ankle joints as well as foot changes. The overwhelming majority of studies have found obesity to negatively impact ambulation by shifting center of mass (COM), increasing metabolic cost, decreasing cadence …

The Relationships Between Using The Rating Of Perceived Exertion, Metabolic Equivalent And Maximum Heart Rate At Ventilatory Threshold Into Determine Appropriate Exercise Prescription For Intensity In Obese Diabetic Patients: A Preliminary Study, Yan-Wen Chen, Francois Liang, Sen-Wei Tsai, Shih-Yi Lin, I. T. Lee, Sheu-Chen Liu, Shin-Shan Lu

Rehabilitation Practice and Science

Background: The rating of perceived exertion (RPE), metabolic equivalent (MET) and maximum heart rate (HRmax) at ventilatory threshold (VT) are commonly used methods as physiological parameters for monitoring exercise intensity. However, the appropriate levels of training intensity for obese type 2 diabetic diabetes mellitus (type 2 DM) patients have not been established.Purpose: To examine the parameters in obese Type 2 DM patients at ventilatory threshold, the exercise capacity of obese Type 2 DM patients, and to determine the appropriate levels of exercise intensity for exercise prescription in obese type 2 DM patients was investigated.Methods: Twenty obese type 2 DM patients …

Obesity And Physical Function In Rural Women Who Enroll In A Lifestyle Modification Intervention For Reducing Blood Pressure, Patricia A. Hageman, Carol H. Pullen, Paul J. Dizona, Kristin Schmidt, Linda S. Boeckner

Journal Articles: Physical Therapy

Purpose: Rural women have high prevalence of obesity and prehypertension. Obesity, if associated with poor physical function, may have implications for applying activity guidelines for women volunteering for lifestyle modification. This study examined associations of body mass index (BMI) and percent body fat with measures of 1-mile walk time, post-walk perceived exertion, and 10-repetition chair stands in rural women ages 40-69.

Methods: Cross-sectional baseline data were collected using standardized methods from 289 rural women with prehypertension who volunteered for a lifestyle clinical trial for reducing blood pressure. ANOVAs and linear regression were used for analysis.

Results: With exception of the …

Neither Heavy Nor Light Load Resistance Exercise Acutely Exacerbates Lymphedema In Breast Cancer Survivor, Prue Cormie, Daniel A. Galvao, Nigel A. Spry, Robert Newton

Research outputs 2013

Resistance exercise has great potential to aid in the management of breast cancer-related lymphedema (BCRL), but little is known regarding the acute response of performing resistance exercises with the affected limb. Purpose. To examine the acute impact of upper body resistance exercise on the amount of swelling and severity of symptoms in women with BCRL and to compare these effects between resistance exercise involving high and low loads (heavier vs lighter weights). Methods. Seventeen women aged 61 ± 9 years with mild to severe BCRL participated in this study. Participants completed a high load (6-8 repetition maximum) and low load …

Use Of Dance As A Medium For Providing An Active Leisure Option For Adults With Developmental Disabilities At L'Arche Tahoma Hope, Sarah Klemme

School of Occupational Therapy Master's Theses (2010-2015)

Obesity and reduced active leisure involvement are prevalent problems among core members with developmental disabilities living at L’Arche Tahoma Hope. As a result, core members may be less likely to participate in meaningful activities. Due to a variety of factors, L’Arche experienced difficulty with ways to increase everyday active leisure. A dance DVD and accompanying manual were created to help ameliorate the prevalence of obesity among core members and provide a fun, active leisure option. The content of the dance DVD includes: warm-up, stretching, dance routines with strengthening and aerobic components as well as a cool-down. L’Arche will be able …

In The Shadow Of Obesity: The Female Triad, Jane Shimon

Jane Shimon

Deliberate efforts to control body weight (e.g., purposeful dieting, prolonged fasting, self-induced vomiting, the use of diet pills), or unintentional restriction of energy intake that does not cover the costs of energy expenditure, all have a role in creating low energy stores (Golden, 2002; Manore, 2002). However, when young females develop patterns of unhealthy eating in conjunction with strenuous exercise during this window of bone accrual, menstrual dysfunction and low estrogen levels that may result can undo the beneficial effects of exercise on bone density (Drinkwater et al., 1984; Gordon, 2003; Miller, 2003) and place amenorrheic females at risk for …

Using The Alter-G Treadmill System With An Extremely Obese Female: A Case Study, Shawn Simonson, Jane Shimon, Elaine Long, Brooke Lester

Jane Shimon

PURPOSE: The present case study examined the potential use of the AlterG Anti-Gravity Treadmill as treatment modality for extreme obese individuals. The special effect of the treadmill reduces ground reaction forces during walking through the use of lower body positive pressure. METHODS: One extremely obese (BMI 69.2) Caucasian 44 year-old female utilized the AlterG Anti-Gravity Treadmill during a 14 wk walking program to pilot test the protocol. RESULTS: At the conclusion of the study, exercise tolerance time increased 3-fold (initially 20 min increased to 65 min) while caloric expenditure increased 4-fold (initially 91.0 kcal/session increased to 442.7 kcal/session) without an …

The Nature Of Social Support: Self-Efficacy In Overweight And Obese Adolescents, Jenna Bastianello, Matt Epkey, Katy Mcmullin

Mental Health

The purpose of this mixed methods study was to describe the relationship between self-efficacy and social support among overweight and obese adolescents at a weight-management camp. Twenty-three participants completed a pre- and post-camp questionnaire based on modified versions of the GSE Scale and the SSQSR. Additionally, seven females and six males engaged in focus group discussion at the beginning and at the end of camp. Statistical analysis of the modified GSE Scale and SSQSR surveys was completed. Dialogue and field notes from focus group discussions were transcribed and analyzed by the researchers to develop themes. Throughout discussion, participants identified the …

Associations Of Cardiorespiratory Fitness And Fatness With Metabolic Syndrome In Rural Women With Prehypertension., Patricia A. Hageman, Carol H. Pullen, Melody A. Hertzog, Linda S. Boeckner, Susan Noble Walker

Journal Articles: Physical Therapy

BACKGROUND: This study investigated the associations of fitness and fatness with metabolic syndrome in rural women, part of a recognized US health disparities group.

METHODS: Fitness, percentage body fat, BMI, and metabolic syndrome criteria were assessed at baseline in 289 rural women with prehypertension, ages 40-69, enrolled in a healthy eating and activity community-based clinical trial for reducing blood pressure.

RESULTS: Ninety (31%) women had metabolic syndrome, of which 70% were obese by BMI (≥30 kg/m²), 100% by percentage body fat (≥30%), and 100% by revised BMI standards (≥25 kg/m²) cited in current literature. Hierarchical logistic regression models, adjusted for …