Medicine and Health Sciences Commons^™

Targeted Deletion Of Cxcl1 In Mscs Regulates Osteogenesis And Suppresses Bone-Metastatic Prostate Cancer, Catherine S. Johnson, Diane L. Costanzo-Garvey, Julio C. Valencia, Sanjana Rajgopal, Theodore Reed, Emma R. Brannon, Jeremy S. Frieling, Deanna Mosley, Todd A. Wyatt, Elijah F. Edmondson, Kabhilan Mohan, Grinu Mathew, Leah M. Cook

Journal Articles: Environmental, Agricultural & Occupational Health

Bone metastasis continues to be the greatest challenge in treating patients with prostate cancer despite ongoing research. In bone, prostate cancer tumors hijack normal bone remodeling processes to drive cancer progression. However, it is unclear how these interactions drive bone-metastatic prostate cancer growth in the bone environment. To understand the mechanisms associated with bone-metastatic prostate cancer regulation of mesenchymal stem cells (MSC), we previously identified that bone-metastatic prostate cancer induces MSC expression of the pro-inflammatory chemokine CXCL8 and its mouse functional homologue Cxcl1. To date, there has been little to no information about the role of CXCL1/8 in MSC biology …

Estimating Per-Infection Cost And Burden For Dengue And Zika As A Function Of Antibody-Dependent Enhancement, Christopher M. Kribs

Mathematics Faculty Publications - Archive

The complex immune interactions produced by the tetravalent dengue vaccine Dengvaxia have foregrounded the important role of antibody-dependent enhancement (ADE) in dengue infection. Some evidence exists that ADE may extend beyond the four dengue serotypes to Zika, a closely related flavivirus transmitted by the same mosquito species as dengue, and may also account for the increased severity of some cases. Estimates of the public health impact of dengue vaccination may then need to include its effects on the transmission of Zika in addition to dengue. This study gathers primary references to build estimates of per-case economic cost and disease burden …

Pedestrian Safety South Of Brigham Young University Campus, Emma Mayo, Alisha H. Redelfs

Library/Life Sciences Undergraduate Poster Competition 2025

8,500 crossings happen on 800 North every day. In Provo last year, 57 car crashes involved pedestrians. A pedestrian’s view of the road is obstructed by cars parked on the right hand side of the road causing them to walk in the crosswalk to see if there is a car coming. Sidewalks on connecting streets are uneven and cracked. Multiple blocks on 800 North without a stop sign to slow drivers down. Currently no posted speed limit signs on 800 North. Drivers can’t see pedestrians crossing on 200, 300, 400, or 500 East because of inadequate lighting. Cars obstruct areas …

Maternal Health Predictors In Ohio, Sritha Donepudi, Humza Khan

Scholarship in Medicine - All Papers

Background: Ohio has continued to have a maternal mortality rate higher than the average which has posed the question of how geographic location, socioeconomic status, and demographics affect these rates.
Objective: This paper aims to investigate the relationship between variables affecting maternal mortality rates in Ohio such as teen birth rates and primary care physician access with where one lives between Rural and Urban areas and their household income in order to provide more information for future research.
Methods: This paper utilized County Health Rankings and statistical and correlation analysis with SPSS to analyze rates across counties in Ohio.
Results: …

The Impact Of Health Promotion Home Visits On Loneliness In An Older Adult Population, Jean M. Herb

West Chester University Doctoral Projects

Loneliness among older adults is a significant public health concern associated with adverse physical, emotional, and cognitive outcomes. Despite widespread recognition of the issue, effective interventions remain limited in clinical practice. This Doctor of Nursing Practice (DNP) project implemented and evaluated a Health Promotion Home Visit (HPHV) intervention designed to reduce loneliness in community-dwelling adults aged 65 and older. A quality improvement initiative using a pre-post design was conducted at a community outreach division of a home health agency. Patients received HPHV every other week over an eight-week period. The UCLA Loneliness Scale (Version 3) was used to assess loneliness …

Institute Of Public Health Newsletter, January - December 2025, Institute Of Public Health (Iph)

Institute of Public Health Newsletter (IPHNL) and Other Publications

No abstract provided.

A Parent's Guide To Success, Marina D. Bucciarelli

Entry Level Occupational Therapy Doctoral Capstone Projects Class of 2025

A Parent’s Guide to Success, a doctoral capstone project, explored occupational therapy’s (OT) role in family-centered practice (FCP). The project focused on areas of education, advocacy, and program development which were informed by the completion of a scoping review. This capstone project was developed as a primary prevention resource for parents and caregivers of children from birth to three years. It was designed to prepare, inform, and support new parents and caregivers with educational videos and resources that depict the skills, knowledge, and support needed for optimized family outcomes. Education was also a valuable aspect of this project as the …

The Intersection Of Indigenous Medicine And Biomedicine In Santiago, Chile, Sam Boehm

Hispanic Studies Honors Papers

No abstract provided.

Adolescents Sexual Health Education Disparities: A Comparative Study Of Inclusion, Cultural Barriers, Access, Policy In Relation To Health And Long Term Outcomes​, Sofia Vega

Nursing | Student Research Posters

Currently, across the different states, sexual health education varies in a range of comprehensive sexual health education to limited sexual health education. These differences in curriculum are not only different from each other but also within themselves. This creates disparities in the knowledge and access among adolescents within their sexual health, which then creates a range of complications involving confidence in knowledge, pregnancy, STIs, and overall inclusion. When granting access to contraceptives on an educational campus, along with education on contraceptives, it allows students to access these tools in a safe environment and increases usage of condoms, lowering the risk …

Prepared To Protect: Improving Cardiac Emergency Response Through Education And Action Planning In Youth Club Sports, Melissa Garcia

Nursing | Senior Theses

Sudden cardiac arrest (SCA) is the leading cause of death in youth sports, illuminating the essential demand for adequate emergency response, including cardiopulmonary resuscitation (CPR), automated external defibrillator (AED) usage, and comprehensive emergency action plans (EAPs). Research shows that despite the importance of prompt intervention, the majority of youth club sports programs outside of the school setting lack the training and resources needed to respond effectively to SCA incidents. This study will evaluate the effectiveness of an educational seminar that includes CPR/AED training and EAP simulation exercises in improving participants’ knowledge, skills, and confidence in managing cardiac emergencies. A quasi-experimental …

Awareness Of The Physiological Changes Occurring In Older Adults Can Reduce Dehydration And Electrolyte Imbalances, Lisa Isley

Nursing | Senior Theses

Background: Individuals over 65 years are at an increased risk of dehydration. The physiological changes that occur with age and medication consumption can cause fluid and electrolyte imbalances that can physically and mentally impair individuals over 65 years old. Objective: By providing education to individuals 65 years and older regarding the significance of drinking water and consuming electrolytes daily, older adults can reduce their dehydration symptoms and improve their quality of life. Method: The proposed research is a quasi experimental study geared towards individuals 65 years and older. The quasi-experimental study will include two pre-surveys and then two post-surveys. The …

Mistrust Among Injured Immigrant Workers: A Conceptual Framework, Maude Arsenault, Daniel Côté, Jessica Dubé

Revues de littérature, synthèses de connaissances

Background

In Quebec, injured workers have access to medical assistance, wage replacement indemnities, and rehabilitation measures, with most injuries resolved easily. However, a small percentage of cases require a lengthy rehabilitation process, which is particularly complex when involving immigrants. The therapeutic alliance is at the heart of the process, involving mutual trust and confidence and a degree of consensus about the therapeutic interventions to be used and, ultimately, the return to work.

Objective

This article delves into the concept of mistrust as more than the absence of trust, and sheds light on its role in the rehabilitation process of immigrant …

The Intersection Of Broadband And Health: Exploring Rural-Urban Disparities In Colorado, Hunter Anderson, Kristen Paradine

Scholarship in Medicine - All Papers

Modern healthcare infrastructure and progression depend on robust and reliable broadband access. Many areas of the U.S., however, still face limited access which exacerbates access to care and healthcare inequities. These trends can be observed in rural counties across the country, where resource constraints and reduced access to infrastructure remain limited. The correlation however between different health outcomes and broadband access in Colorado has not been widely explored in literature.
This study examines the relationship between broadband availability and different healthcare outcomes for rural and urban counties of Colorado by utilizing data from the County Health Rankings and Roadmaps for …

Intrinsic And Extrinsic Factors That Affect High School Graduation In California, Anisha Mandava, Joseph Pedregon

Scholarship in Medicine - All Papers

High school graduation is an essential milestone that indicates success later in life. In particular, high school students in California may encounter many obstacles that hinder their opportunity to acquire a high school diploma or equivalent certificate. So, what are these obstacles that students encounter on their journey through high school education? Here we seek to identify whether intrinsic factors, like disconnected youth and educational scores, or extrinsic factors, like segregation, funding, and food insecurity, have a larger impact on the student to reach high school completion. In our study, we utilized data from County Health Rankings for statistical analysis. …

Addressing Deaths Of Despair: The Impact Of Loneliness On Excessive Alcohol Use And Alcohol-Involved Driving Deaths In Ohio, Juliana Zacher, Akshey Suresh, Dylan Timperman

Scholarship in Medicine - All Papers

Alcohol-related driving deaths and excessive alcohol consumption continue to rise across the United States. These trends have had a large impact on historically disadvantaged populations, such as Appalachia, being disproportionately affected. Previous literature suggests factors such as loneliness, mental distress, segregation, and immigration status amongst others may contribute to this increase in drinking. Although delineating a clear role of the nature of the impact at a community level still remains unclear. Our objective was to explore these very factors as well as to identify social and economic predictors to explain alcohol-related driving deaths and excessive drinking in Ohio between 2016 …

Regional Variation And Correlation Of Big Five Personality Traits With Rates Of Insufficient Sleep And Diabetes In The United States, Isabella Chirakos, Brennan Schroeder

Scholarship in Medicine - All Papers

Background: Diabetes and insufficient sleep are prevalent health concerns, and determining potential contributing factors could help decrease the incidence of these issues. This study aims to explore potential associations between insufficient sleep and diabetes mellitus, examining whether these negative health outcomes can be linked geographically and by personality traits. Results could help create more effective programs to combat diabetes and insufficient sleep.
Materials and Methods: The study utilized longitudinal health data and roadmaps from 2016 and 2023 for each state, categorizing the data into four regions: Northeast, Midwest, South, and West. We incorporated personality data from the Synthetic Aperture Personality …

Sars-Cov-2 Genomic Surveillance Using Self-Collected Saliva Specimens During Occupational Testing Programs, Andy T. Schnaubelt, David Brett-Major, Janet Williamson, Bailey Barcal, Julie Carstens, Ashley Peer, Michael R. Wiley, M. Jana Broadhurst

Journal Articles: Epidemiology

Continually emerging SARS-CoV-2 variants pose challenges to clinical and public health interventions, necessitating sustainable approaches to real-time variant monitoring. This case study describes an innovative SARS-CoV-2 screening and surveillance program that demonstrates the utility of sequencing-based variant monitoring using self-collected saliva specimens. We conducted saliva-based SARS-CoV-2 screening in occupational settings in Omaha, Nebraska from December 2021 through November 2022. 8,372 saliva specimens collected from 1,480 participants were tested for SARS-CoV-2 RNA by extraction-free PCR, with 334 positive samples referred for whole-genome sequencing analysis. Program utilization, quality metrics, and sequencing outputs were compared across sites. Specimen quality was high across program …

Knowledge, Perception And Acceptability Of Human Papillomavirus Vaccine Among Moroccan Medical Students, Safa Ibork, Asmaa Naim, Mohamed Khalis, Soumaya Rafii, Abire Allaoui

Health Sciences

Background:

Cervical cancer is the second most common cancer among women and the third leading cause of cancer-related mortality in Morocco. In October 2022, the Ministry of Health introduced the human papillomavirus (HPV) vaccine into the national immunization program. This study aimed to assess knowledge, satisfaction, and acceptability regarding HPV infection and vaccination among Moroccan medical students.

Methods:

A cross-sectional study was conducted between September 2021 and July 2022 among fifth-year and higher medical students from all nine Moroccan medical universities. Data were collected through an online questionnaire and analyzed descriptively and analytically.

Results: A total of 636 students participated …

Evaluating Ai-Generated Essays For Bias In Public Health Topics, Spring Cooper

Open Educational Resources

This is a sample assignment: Students will use AI tools to generate essays on public health topics, critically evaluate these essays for potential biases, and understand the ethical implications of using AI-generated content in public health.

Third Party Negotiated Hospital Pricing In Rural And Urban Hospitals Within 12 U.S. States, Lindsey R. Hammerslag, Aaron P. Smith, Jeffrey C. Talbert

Rural & Underserved Health Research Center Publications

No abstract provided.

A Comparative Analysis Of Stress Relief, Life Satisfaction, And Quality Of Life Based On Marriage Status And Gender Among Members Of Society Participating In Exercise, Ji-Hye Yang, Sicheol Jung, Hyejin Yang, Chulhwan Choi, Chul-Ho Bum

Human Movement Studies & Special Education Faculty Publications

Modern members of society tend to feel stressed in their workplace and at home, but exercising has been shown to effectively reduce stress and increase quality of life and satisfaction. This study aimed to investigate and compare stress relief, life satisfaction, and quality of life based on marriage status and gender among members of society who participate in exercise. We used a questionnaire survey with 311 participants, and the data were analyzed using descriptive statistics, validity and reliability, a multivariate analysis of variance (MANOVA), and a post hoc analysis. The study results showed that the single groups demonstrated higher mean …

Revolutionising Indoor Air Quality To Stop Pandemics With Germicidal Ultraviolet (Guv) Technology, P. Jacob Bueno De Mesquita

Arts & Sciences Faculty Publications

This exclusive interview with Assistant Professor of Public Health and leader of TheHuman Health and Harmony Lab (H3) Jacob Bueno de Mesquita explores the hiddendangers of shared air, the transformative potential of Germicidal Ultraviolet (GUV)technology, and the vision for a future where indoor spaces contribute to healthier, moreresilient communities.

Establishing The Philippine Cancer Center National Cancer Research Agenda 2024-2028: Insights And Future Directions, Frederic Ivan L. Ting, Edward Christopher Dee, Ma Katrina Domenica R. Ting, Abigail R. Tud, Erin Jay G. Feliciano, Erika P. Ong, Carol V. Narra

Ateneo School of Medicine and Public Health Publications

No abstract provided.

Enablers And Barriers To The Use Of Portable Ultrasound Devices For Antenatal Care In Rural Health Centers In The Philippines, Jacob Anthony Batuhan, Reynan Hernandez, Florentina Villanueva, Airen Sigue, Kevyn Yu, Kate Wad-Asen, Beatriz Carandang, Jeremie Bartelheimer

Ateneo School of Medicine and Public Health Publications

Objectives

This qualitative study aims to examine the enablers and barriers to portable ultrasound device utilization for antenatal care in rural Philippine health centers, with the goal of improving maternal outcomes and reducing maternal mortality.

Methods

We conducted focus group discussions with 18 healthcare workers (midwives, a nurse, and a radiologic technician) and 20 pregnant women across 5 rural health centers. We used inductive thematic analysis to identify system-related, provider-related, and client-related enablers and barriers.

Results

Enablers included free ultrasound services, hospital policies requiring prenatal scans, provider training, awareness creation, patient interest and acceptance, and confidence in HCWs’ capabilities. Barriers …

Intersection Between Individual, Household, Environmental And System Level Factors In Defining Risk And Resilience For Children In Kenya’S Asal: A Qualitative Study, Esther Chongwo, Barack Aoko, Martha Kaniala, Moses Wesala, Phillis Magoma, Eunice Njoroge, Susan Nyamanya, Joyce Marangu, Anil Khamis, Amina Abubakar

Institute for Human Development, East Africa

Introduction: Children growing up in arid and semi-arid regions of Sub-Saharan Africa (SSA) face heightened risks, often resulting in poor developmental outcomes. In Kenya, the arid and semi-arid lands (ASAL) exhibit the lowest health and developmental indicators among children. Despite these risks, some children grow up successfully and overcome the challenges. However, there is limited comprehensive data on sources of risks and resilience in these children, particularly research that incorporates community perspectives and indigenous knowledge. Systematic documentation of factors influencing child outcomes is crucial for understanding the overall burden, informing policy and implementing targeted interventions. This study aimed at …

Factors Affecting The Joy Of Life In Old Age: A Scale Development Study, Yalçın Karagöz, Yusuf Karaşi̇n, Mustafa Filiz, Mehmet Ateş

Adultspan Journal

This study aims to introduce a measurement tool into the literature that can reveal the factors affecting the joy of life in older adulthood. Participants included 266 individuals aged 55 and over living in Izmir, Turkey. The process of developing the scale includes the following stages: problem identification, item pool creation, expert opinion, form shaping, pilot application, and finalizing the scale. The exploratory factor analysis revealed that the scale consists of 6 different dimensions, and the variance explained by these dimensions was found to be 65.184%. The acceptable values for the scale's fit indicators are as follows: χ²/df0.90, IFI > 0.90, …

Drone Medical Package Delivery For Improved Transportation And Better Patient Outcomes Final Implementation Report, Amro El-Adle, Madeline Alden, Yin-Hsuen Chen, Melissa Davidson

Information Technology & Decision Sciences Faculty Publications

The Drone Medical Package Delivery for Improved Transportation and Better Patient Outcomes planning and prototyping grant involves five partners, including Accomack-Northampton Planning District Commission (A-NPDC), Riverside Health System, Old Dominion University (ODU), Virginia Institute for Spaceflight & Autonomy (VISA), Virginia Innovation Partnership Corporation (VIPC), and DroneUp. The partners worked together to address access, safety, reliability and sustainability for medical and emergency response package delivery via drone, specifically, where the use of aerial drones could lead to better patient outcomes and improved safety and emergency response.

The goal of the project was to develop an operational prototype that woul evolve into …

Perinatal Policy Disparities And Their Impact On Maternal, Paternal, And Child Health, D'Ashanae Y. Pippens

Theses and Dissertations

This systematic review synthesized evidence on perinatal policy framework to evaluate their public health significance and impact on family outcomes. Following Preferred Reporting Items for Systematic Reviews Meta-Analyses (PRISMA) methodology, peer-reviewed literature, policy documents, and corporate data from 2015-2025 were reviewed across national, state, and global levels. The analysis revealed seven thematic domains, (1) policy design and duration, (2) wage replacement, (3) insurance continuity, (4) workplace breastfeeding accommodations, (5) parental leave, (6) equity in access, and (7) policy enforcement. Evidence shows that integrated and inclusive policies particularly those in Sweden, Germany, and progressive U.S. states (NY and CA), yield substantial …

Small Town Voices And Stories: Rural Older Populations And Health Narratives, Wyatt K. Zumbahlen

Masters Theses

Stories play a vital role in our humanity; they help us understand the world around us. As we age, our experiences, along with those of the people around us, shape our perceptions of health and influence our healthcare choices. For older adults, narratives become an essential resource in making healthcare decisions. In rural communities like Coles County, Illinois, these stories are especially important for older adults who are navigating the limited care and services available in the area. This reliance on narratives impacts their willingness to seek care, highlighting the need to recognize the power of stories in empowering older …

Spontaneous Pneumothorax In Adolescents: Is Video-Assisted Thoracoscopy Mandatory?, Soufiane Essamoud, Mohamed Lahlou, Anne Olland, Francois Lefebvre, Anne Lehn, Isabelle Chevalier, Raphael Moog, Pierre-Emmanuelle Falcoz, Isabelle Talon, Hicham Zerhouni

Health Sciences

Background: Treatment of spontaneous pneumothorax involves conservative treatment or surgery. Our goal was to evaluate the need for surgical approach using Video- Assisted Thoracoscopic Surgery (VATS) for patients presenting spontaneous pneumothorax. Methods: Patients aged between 14 and 20 years old treated for spontaneous pneumothorax were included into an observational retrospective study. Patients were divided into two groups: Those with a success of conservative treatment at the initial presentation (Group A), and those where VATS was performed at initial presentation after failure of conservative treatment (Group B). Results: 134 patients were included with a median of 6.5 years follow-up. 102 (76,1%) …