Medicine and Health Sciences Commons^™

Voices From The Street: Comics For Young Men On Masculinity, Sexuality And Hiv—An Evidence-Based Communication Initiative, Vijaya Nidadavolu, Leena Joshi, Vinita Nathani, Atanu Ghosh, Isidore Phillips

HIV and AIDS

HIV infection is spreading rapidly among young people in India. With more than 30 percent of new infections in 2006 in the 15–29-year age group, the need to address the vulnerability of this population subgroup is pressing. Existing literature shows that young men subscribe to norms of masculinity that lead to risky behavior patterns. Misinformation about HIV coupled with a low perception of risk to themselves make young men even more vulnerable. To bring about social and attitude change in the long-term, communication strategies that are evidence-based, culturally appropriate, and designed in consultation with target audiences are needed. The Population …

Care Patterns And Outcomes For Hospitalized Patients With Diabetes In Nevada, Jay J. Shen

Nevada Journal of Public Health

This study demonstrates substantial differences between Nevada and the national average in patterns of hospital based care in patients with type 2 diabetes. Diabetic patients in Nevada are more likely to be hospitalized through the emergency department, and more likely to be admitted for a condition related to diabetes. Moreover, in Nevada, Medicaid and uninsured patients with diabetes are more likely to experience adverse outcomes then their privately insured counterparts. These differences may be primarily reflective of variances in access to ambulatory care, care seeking behavior, and availability of health services and facilities. Policies promoting expansion of health care benefits …

Cover - Front Matter - Table Of Contents

International Journal of Global Health and Health Disparities

No abstract provided.

Utilization Of Low Cost Waste Material Bagasse Fly Ash In Removing Of Cu2+, Ni2+, Zn2+ And Cr3+ From The Industrial Waste Water, G. M. Taha

International Journal of Global Health and Health Disparities

Bagasse fly ash, a waste material generated in sugar industry, collected from a local sugar Firm at Kom-Ombo district (42Km - distance, on the northern direction, from the mid city of Aswan ), Aswan Governorate, Egypt was utilized as a low cost and effective adsorbing surface for the removal of Cu²+, Ni²+, Zn²+ and Cr³+ from the industrial wastewater. The adsorption capacity was followed as a function of pH, adsorbent dose, metal ion concentration, shaking time and divers ions. Under the optimum conditions used, more than 95% of some of the ions …

Sources Of Stress And Its Impact On Health Behaviors And Academic Performance Of International Students At A Comprehensive Midwestern University, Israel Gabriel Msengi

International Journal of Global Health and Health Disparities

The purpose of this study was to investigate the sources of stress, its impact on health behaviors and academic performance of 220 international students studying at a comprehensive Midwestern university, and coping strategies used by international students to manage stress. The study was a cross-sectional descriptive design, using a quantitative method. Two hundred twenty international students enrolled at the university during the summer and fall of 2003 participated in this study. Data were collected using "Sources of Stress, Health Behaviors and Academic Performance Scale for international students. Statistical procedure for data analysis included t-test, ANOVA, chi-square and bivariate correlation. Results …

Routes Of Exposure For Leptospirosis, Catherine C. Schmidt

International Journal of Global Health and Health Disparities

Leptospirosis was once a common zoonotic disease affecting most mammalian species. While it was once a very prevalent disease, it had tailored off only affecting humans with certain occupational hazards in developed countries. Recently, there has been an increase in the incidence of leptospirosis associated with recreational exposures and travel to tropical climates. Humans become infected with the disease through either direct or indirect contact with infected animal urine. Since leptospirosis has a longer survival period in wet, humid and warm conditions it is more prevalent in tropical and temperate climates and exposure peaks in the summer. There are a …

Barriers To Condom Use And Hiv Infection In Latino Youth, Jacqueline M. Leung-Heras

International Journal of Global Health and Health Disparities

Although Latinos make up only about 14% of the population of the United States, including Puerto Rico, they accounted for 18% (almost 164,000) of the more than 886,500 AIDS cases diagnosed since the beginning of the epidemic.² Of the rate of AIDS diagnoses for all racial and ethnic groups, the second highest was the rate for Latinos. Despite the potential consequences of having unprotected sexual intercourse, many Latino adolescents do not use condoms at first intercourse or use condoms on a regular basis.^{3, 4} Several factors influence condom use among Latinos. Adolescents who initiate sex at later ages …

The Effects Of Smoking On Low Birth Weight Babies: A Cultural Influence?, Jodie Sample

International Journal of Global Health and Health Disparities

The persistence of low birth weight babies born to mothers who smoke continues to be a source of social concern. Recent research determined that a pregnant woman who smokes is 1.5 times more likely to deliver a low birth weight baby than a nonsmoker (Ventura et al. 2003). Low birth weight affects one in 13 babies each year in the United States and is a factor in 65% of infant deaths (March of Dimes, 2003). According to the March of Dimes Foundation, babies born at a low birth weight (2500 grams or less) are at a greater risk for mental …

A Review Of Case-Control And Cohort Studies Examining Pesticides And The Risk Of Parkinson's Disease, Ruth Moytca Parks

International Journal of Global Health and Health Disparities

Parkinson's disease (PD) is the second most common neurodegenerative disease after Alzheimer disease, having an annual incidence of approximately 20 per 100,000 people (Schapira 2004, Fischer 1999). An estimated one million persons in the United States have PD, and this prevalence is likely to rise as the population ages (Schapira 2004). This disorder is characterized pathologically by a loss of dopamine neurons in the substantia nigra pars compacta that produces the neurotransmitter dopamine. The clinical features of PD are motor function abnormalities including tremor, rigidity, slowness of movement, and difficulty with balance. In the early stages of PD, treatments may …

Information For Authors

International Journal of Global Health and Health Disparities

No abstract provided.

Responsibility For Hiv Prevention: Patterns Of Attribution Among Hiv-Seropositive Gay And Bisexual Men, C. Offer, O. Grinstead, E. Goldstein, Edward M. Mamary, N. Alvarado, J. Euren, W. Woods

Faculty Publications

The article presents research based on narratives by gay and bisexual men recently infected with HIV. Researchers looked at the men's attributions of responsibility for infection, comparing recollections of feelings before becoming infected with views expressed after seroconversion. The research responds to a call to better understand risk behavior among HIV-positive persons, in an effort to craft effective prevention interventions. In both before-and after-HIV infection views, survey participants expressed a sense of personal responsibility. Researchers report also nuances of views about shared responsibility.

Alternative And Complementary Health Practices (Achp) Among Older Urban African Americans, Beverly Wolpert, Priscilla T. Ryder, Denise Orwig

Scholarship and Professional Work – COPHS

Slides from presentation at: The 135th APHA Annual Meeting & Exposition (November 3-7, 2007) of APHA

Investigating The Effects Of An Elective Abortion On Women's Mental Health, Marilyn Schneiderman

Graduate Research Papers

The purpose of this research project is to investigate evidence that an elective abortion affects a woman's mental health. Included are literature reviews and studies aimed at gathering information and quantifying these effects. Because this is a highly politicized and controversial topic, it has been difficult to find objective resources. Several areas are addressed: the difference between short vs. long-term effects on a woman's mental health subsequent to an elective abortion, evidence of delayed grief reaction and the link with post-traumatic stress disorder (PTSD). Post-Abortion Stress is defined and specific psychological sequelae are addressed such as grief, depression, anxiety and …

Post-Operative Extended Volume External Beam Radiation Therapy Is Safe For High Risk Esophageal Cancer Patients, Edward Yu, Patricia Tai, Jawaid Younus, Richard Malthaner, Larry Stitt, Pauline Truong, George Rodrigues, Robert Ash, Rashid Dar, Anna Tomiak, Mark Vincent, Walter Kocha, Brian Dingle, Richard Inculet

Oncology Presentations

Post-operative radiation therapy (RT) (1) and post-operative chemoradiation (2) have been used for esophageal cancer patients deemed high risk for recurrence after esophagectomy.

Defining opitmal RT target volume after esophagectomy is difficult due to significant changes in patient anatomy and function.

Some radiationon cologists advocated the inclusion of the anastomotic site within the irradiation volume due to concerns for potential increased relapse risk, while others did not subscribe to this practice due to concerns for increased treatment related toxicity.

We have previously reported patient outcome benefit using extended volume RT In management with high risk esophageal cancer patients underwent esopagectomy(3). …

Social Support And Thriving Health: A New Approach To Understanding The Health Of Indigenous Canadians, Chantelle A.M. Richmond, Nancy A. Ross, Grace E. Egeland

Aboriginal Policy Research Consortium International (APRCi)

Objectives. We examined the importance of social support in promoting thriv- ing health among indigenous Canadians, a disadvantaged population.

Methods. We categorized the self-reported health status of 31 625 adult indig- enous Canadians as thriving (excellent, very good) or nonthriving (good, fair, poor). We measured social support with indices of positive interaction, emotional support, tangible support, and affection and intimacy. We used multivariable lo- gistic regression analyses to estimate odds of reporting thriving health, using social support as the key independent variable, and we controlled for educational attainment and labor force status.

Results. Compared with women reporting low levels of …

Learning From The Grandmothers: Incorporating Indigenous Principles Into Qualitative Research, Charlotte Loppie

Aboriginal Policy Research Consortium International (APRCi)

In this article, the author describes the process she undertook to incorporate Indigenous principles into her doctoral research about the midlife health experiences of elder Aboriginal women in Nova Scotia, Canada. By employing qual- itative methods within the context of an Indigenous worldview, she gained knowledge of and developed competence in Aboriginal health research. The emergent partnership among Aboriginal community research facilitators, participating Mi’kmaq women, and the researcher provided many opportunities for the researcher to incorporate the paradigmatic and methodological traditions of Western science and Indigenous cultures. The application of these principles to this study might provide a useful example …

Evaluation Of A Behavioral Health Integration Program In A Rural Primary Care Facility, Tina W. Billmeyer

Theses, Dissertations and Capstones

Behavioral or mental health has historically been seen as a separate entity from medical or primary health care. With the increased utility of psychotropic medication, more and more patients are presenting to their primary care provider with behavioral health issues prompting the healthcare field to look for methods to integrate medical and behavioral health services. The current study examined the effectiveness of a pilot program that attempted to integrate services at a rural primary care clinic. The study asked whether participation in the program resulted in improved scores on a questionnaire of perceived health status and whether participating medical providers …

Disclosure Of Maternal Hiv Status To Children: To Tell Or Not To Tell . . . That Is The Question, Tanya L. Tompkins

Faculty Publications

HIV-infected mothers face the challenging decision of whether to disclose their serostatus to their children. From the perspective of both mother and child, we explored the process of disclosure, providing descriptive information and examining the relationships among disclosure, demographic variables, and child adjustment. Participants were 23 mothers and one of their noninfected children (9 to 16 years of age). Sixty-one percent of mothers disclosed. Consistent with previous research, disclosure was not related to child functioning. However, children sworn to secrecy demonstrated lower social competence and more externalizing problems. Differential disclosure, which occurred in one-third of the families, was associated with …

Parentification And Maternal Hiv Infection: Beneficial Role Or Pathological Burden?, Tanya L. Tompkins

Faculty Publications

Parentification, along with parenting and child adjustment were examined in 23 9-through 16-year-old youth from families affected by maternal HIV infection and 20 same-age peers whose mothers were not infected. Children whose mothers were HIV-positive reported to more often engage in parental role behaviors, relative to children of HIV-negative mothers. This difference remained even after controlling for the effects of current drug use, number of adults per child in the household, and marital status. Findings revealed a beneficial relationship between parentification and both child adjustment and parenting, particularly among families affected by maternal HIV infection. When relationships were examined separately …

The Use Of Telehealth For Diabetes Management: A Qualitative Study Of Telehealth Provider Perceptions, Faith P. Hopp, Mary M. Hogan, Peter A. Woodbridge, Julie C. Lowery

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Monitoring and Messaging Devices (MMDs) are telehealth systems used by patients in their homes, and are designed to promote patient self-management, patient education, and clinical monitoring and follow-up activities. Although these systems have been widely promoted by health care systems, including the Veterans Health Administration, very little information is available on factors that facilitate use of the MMD system, or on barriers to use.

Methods

We conducted in-depth qualitative interviews with clinicians using MMD-based telehealth programs at two Veterans Affairs Medical Centers in the Midwestern United States.

Results

Findings suggest that MMD program enrollment is limited by both …

Inhibition Of Proteasome Activity By The Dietary Flavonoid Apigenin Is Associated With Growth Inhibition In Cultured Breast Cancer Cells And Xenografts, Di Chen, Kristin R. Landis-Piwowar, Marina S. Chen, Q Ping Dou

Wayne State University Associated BioMed Central Scholarship

Abstract

Introduction

Proteasome inhibition is an attractive approach to anticancer therapy and may have relevancy in breast cancer treatment. Natural products, such as dietary flavonoids, have been suggested as natural proteasome inhibitors with potential use for cancer prevention and therapeutics. We previously reported that apigenin, a flavonoid widely distributed in many fruits and vegetables, can inhibit proteasome activity and can induce apoptosis in cultured leukemia Jurkat T cells. Whether apigenin has proteasome-inhibitory activity in the highly metastatic human breast MDA-MB-231 cells and xenografts, however, is unknown.

Methods

MDA-MB-231 breast cancer cell cultures and xenografts were treated with apigenin, followed by …

Examining Smoking And Cessation During Pregnancy Among An Appalachian Sample: A Preliminary View, Lesley Cottrell, Mark Gibson, Carole Harris, Alia Rai, Sabera Sobhan, Traci Berry, Bonita Stanton

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Several transitions that a woman experiences prenatally may influence her desire or ability to discontinue smoking. This study explores the role of smoking for young, Appalachian, nulliparous pregnant women and their plans for smoking during their pregnancies.

Results

The reports of women and their male partners were taken from baseline interviews conducted during the first trimester of pregnancy. Cigarette smoking appeared to be more than an isolated addictive activity; rather, smoking was interwoven in women's social and personal realms, often changing as their perceptions of self changed. Women and their partners who continued to smoke appeared to be …

Paradoxical Antiproliferative Effect By A Murine Mammary Tumor-Derived Epithelial Cell Line, Esteban N. Gurzov, Sanaa M. Nabha, Hamilto Yamamoto, Hong Meng, O Graciela Scharovsky, R Daniel Bonfil

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Despite significant advancement in breast cancer therapy, there is a great need for a better understanding of the mechanisms involved in breast carcinogenesis and progression, as well as of the role of epigenetic contributions from stromal cells in mammary tumorigenesis. In this study, we isolated and characterized murine mammary tumor-derived epithelial and myofibroblast cell lines, and investigated the in vitro and in vivo effect of cellular soluble factors produced by the epithelial cell line on tumor cells.

Methods

Morphology, immunophenotype, cytogenetics, invasiveness, and tumorigenicity of epithelial (LM-234ep) and myofibroblast (LM-234mf) cell lines isolated from two murine mammary adenocarcinomas …

The Class Ii Major Histocompatibility Complex Molecule Bola-Dr Is Expressed By Endothelial Cells Of The Bovine Corpus Luteum, Matthew J. Cannon, John S. Davis, Joy L. Pate

United States Public Health Resources

Cells expressing class II major histocompatibility complex (MHC) molecules are found within the corpus luteum (CL) of several species. Expression and localization of class II MHC molecules in the bovine CL were examined in the present study. Immunohistochemical evaluation revealed class II MHC molecules on single cells in early CL (days 4 and 5 post-estrus). Two class II MHC-expressing cell types were observed in midcycle CL (days 10–12 post-estrus), single cells similar to those observed in the early CL, and endothelial cells. Not all endothelial cells expressed class II MHC, and further investigation revealed expression of only one type of …

Global Scale Climate–Crop Yield Relationships And The Impacts Of Recent Warming, David Lobell, Christopher Field

United States Public Health Resources

Changes in the global production of major crops are important drivers of food prices, food security and land use decisions. Average global yields for these commodities are determined by the performance of crops in millions of fields distributed across a range of management, soil and climate regimes. Despite the complexity of global food supply, here we show that simple measures of growing season temperatures and precipitation—spatial averages based on the locations of each crop—explain ∼30% or more of year-to-year variations in global average yields for the world’s six most widely grown crops. For wheat, maize and barley, there is a …

Demographic Factors Associated With Prevalence Of Antibody To Sin Nombre Virus In Deer Mice In The Western United States, Charles Calisher, Kent Wagoner, Brian Amman, J. Jeffrey Root, Richard J. Douglass, Amy Kuenzi, Ken Abbott, Cheryl Parmenter, Terry Yates, Thomas Ksiazek, Barry J. Beaty, James N. Mills

United States Public Health Resources

We used long-term data collected for up to 10 yr (1994–2004) at 23 trapping arrays (i.e., webs and grids) in Arizona, Colorado, Montana, and New Mexico to examine demographic factors known or suspected to be associated with risk of infection with Sin Nombre virus (SNV) in its natural host, the deer mouse (Peromyscus maniculatus). Gender, age (mass), wounds or scars, season, and local relative population densities were statistically associated with the period prevalence of antibody (used as a marker of infection) to SNV in host populations. Nevertheless, antibody prevalence and some of the risk factors associated with antibody …

Identification Of Vibrio Isolates By A Multiplex Pcr Assay And Rpob Sequence Determination, Cheryl L. Tarr, Jayna S. Patel, Nancy Puhr, Evangeline Sowers, Cheryl A. Bopp, Nancy A. Strockbine

United States Public Health Resources

Vibrio, a diverse genus of aquatic bacteria, currently includes 72 species, 12 of which occur in human clinical samples. Of these 12, three species—Vibrio cholerae, Vibrio parahaemolyticus, and Vibrio vulnificus—account for the majority of Vibrio infections in humans. Rapid and accurate identification of Vibrio species has been problematic because phenotypic characteristics are variable within species and biochemical identification requires 2 or more days to complete. To facilitate the identification of human-pathogenic species, we developed a multiplex PCR that uses species-specific primers to amplify gene regions in four species (V. cholerae, V. parahaemolyticus, V. …

Annual Report To The Nation On The Status Of Cancer, 1975–2004, Featuring Cancer In American Indians And Alaska Natives, David K. Espey, Xiao-Cheng Wu, Judith Swan, Charles Wiggins, Melissa A. Jim, Elizabeth Ward, Phyllis A. Wingo, Holly L. Howe, Lynn A. G. Ries, Barry A. Miller, Ahmedin Jemal, Faruque Ahmed, Nathaniel Cobb, Judith S. Kaur, Brenda K. Edwards

United States Public Health Resources

BACKGROUND. The American Cancer Society, the Centers for Disease Control and Prevention, the National Cancer Institute, and the North American Association of Central Cancer Registries collaborate annually to provide updated information on cancer occurrence and trends in the U.S. The 2007 report features a comprehensive compilation of cancer information for American Indians and Alaska Natives (AI/AN).

METHODS. Cancer incidence data were available for up to 82% of the U.S. population. Cancer deaths were available for the entire U.S. population. Long-term (1975 through 2004) and fixed-interval (1995 through 2004) incidence and mortality trends were evaluated by annual percent change …

One-Year Changes In Glucose And Heart Disease Risk Factors Among Participants In The Wisewoman Programme, Jc Will, O Khavjou, Ea Finkelstein, Rk Loo, Ky Gregory-Mercado

United States Public Health Resources

Background: WISEWOMAN provides chronic disease risk factor screening, referrals and lifestyle interventions to low-income, uninsured women, to reduce their heart disease and stroke risk. Participants learn behaviour-changing skills tailored to low-income populations, such as collaborative goal setting, the need to take small steps and other empowerment techniques.

Aim: To quantify the baseline prevalence of pre-diabetes (fasting blood glucose 5.5–6.9 mmol/l) and diabetes among WISEWOMAN participants and assess one year changes in glucose levels and other diabetes risk factors.

Methods: We used 1998–2005 baseline and one-year follow-up data from WISEWOMAN participants. Using a multilevel regression model, we assessed …

A Scale-Free Systems Theory Of Motivation And Addiction, R. Andrew Chambers, Warren K. Bickel, Marc N. Potenza

United States Public Health Resources

Scale-free organizations, characterized by uneven distributions of linkages between nodal elements, describe the structure and function of many life-based complex systems developing under evolutionary pressures. We explore motivated behavior as a scale-free map toward a comprehensive translational theory of addiction. Motivational and behavioral repertoires are reframed as link and nodal element sets, respectively, comprising a scale-free structure. These sets are generated by semi-independent information-processing streams within cortical–striatal circuits that cooperatively provide decision-making and sequential processing functions necessary for traversing maps of motivational links connecting behavioral nodes. Dopamine modulation of cortical–striatal plasticity serves a central-hierarchical mechanism for survival-adaptive sculpting and development …