Open Access. Powered by Scholars. Published by Universities.®
- Institution
-
- Western Michigan University (3150)
- The Texas Medical Center Library (2771)
- Population Council (2553)
- Walden University (2222)
- Henry Ford Health (2166)
-
- University of Kentucky (2088)
- Georgia Southern University (1907)
- Universitas Indonesia (1845)
- Thomas Jefferson University (1826)
- University of South Carolina (1569)
- Aga Khan University (1520)
- University of Nevada, Las Vegas (1314)
- Wayne State University (1226)
- Himmelfarb Health Sciences Library, The George Washington University (1153)
- Institut de Recherche Robert-Sauvé en santé et en sécurité du travail (1124)
- University of Nebraska Medical Center (908)
- City University of New York (CUNY) (871)
- Boise State University (805)
- Edith Cowan University (777)
- Old Dominion University (748)
- University of Nebraska - Lincoln (732)
- The Beryl Institute (548)
- Western Kentucky University (541)
- LSU Health New Orleans (536)
- University of South Florida (533)
- SIT Graduate Institute/SIT Study Abroad (516)
- Portland State University (490)
- University of Louisville (460)
- Wright State University (421)
- University of Alabama at Birmingham (417)
- Keyword
-
- COVID-19 (4663)
- Michigan (2866)
- Humans (2708)
- English (2228)
- Public health (1894)
-
- Female (1491)
- Male (1141)
- Georgia Southern University (970)
- Adult (952)
- COVID-19 cases (852)
- Public Health (816)
- Obesity (787)
- Health (717)
- Reproductive Health (686)
- Pregnancy (656)
- HIV (642)
- United States (634)
- Epidemiology (624)
- Mental health (619)
- Middle Aged (610)
- Hospital data (592)
- SARS-CoV-2 (568)
- Aged (549)
- Education (541)
- Family Planning (540)
- Jiann-Ping Hsu College of Public Health (534)
- Adolescent (531)
- Québec (517)
- Poverty Gender and Youth (511)
- Women (472)
- Publication Year
- Publication
-
- Faculty, Staff and Student Publications (2331)
- Henry Ford Hospital Medical Journal (2151)
- Walden Dissertations and Doctoral Studies (2132)
- Reproductive Health (1314)
- Faculty Publications (1224)
-
- Rapports de recherche scientifique (980)
- Patient Education Projects (959)
- Poverty, Gender, and Youth (856)
- Population Health Matters (Formerly Health Policy Newsletter) (798)
- Theses and Dissertations (760)
- Kesmas (728)
- International Journal of Physical Activity and Health (667)
- Publications and Research (595)
- Michigan COVID-19 Hospital Data (594)
- Cumulative Michigan COVID-19 Data (588)
- Journal of Health Disparities Research and Practice (550)
- Patient Experience Journal (548)
- College of Public Health: Faculty Syllabi (2014-2021) (537)
- Daily Michigan COVID-19 Update (498)
- USF Tampa Graduate Theses and Dissertations (496)
- Independent Study Project (ISP) Collection (495)
- Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.) (487)
- Michigan COVID-19 Syndromic Surveillance System Data (443)
- Capstone Experience: Master of Public Health (422)
- Research outputs 2022 to 2026 (403)
- All ETDs from UAB (400)
- Electronic Theses and Dissertations (383)
- Community Health Sciences (379)
- HIV and AIDS (354)
- Journal of the Georgia Public Health Association (331)
- Publication Type
Articles 10651 - 10680 of 54814
Full-Text Articles in Medicine and Health Sciences
An Observational Study To Develop A Predictive Model For Bacterial Pneumonia Diagnosis In Severe Covid-19 Patients-C19-Pneumoscore, Francesca Pozzana, Amato Infante, Luigi Larosa, Maria Antonietta Mazzei, Salvatore Lucio Cutuli, Domenico Luca Grieco, Alessandra Bisanti, Simone Carelli, Gianmarco Lombardi, Edoardo Piervincenzi, Gabriele Pintaudi, Tommaso Pirronti, Mario Tumbarello, Massimo Antonelli, Gennaro De Pascale
An Observational Study To Develop A Predictive Model For Bacterial Pneumonia Diagnosis In Severe Covid-19 Patients-C19-Pneumoscore, Francesca Pozzana, Amato Infante, Luigi Larosa, Maria Antonietta Mazzei, Salvatore Lucio Cutuli, Domenico Luca Grieco, Alessandra Bisanti, Simone Carelli, Gianmarco Lombardi, Edoardo Piervincenzi, Gabriele Pintaudi, Tommaso Pirronti, Mario Tumbarello, Massimo Antonelli, Gennaro De Pascale
Faculty, Staff and Student Publications
In COVID-19 patients, antibiotics overuse is still an issue. A predictive scoring model for the diagnosis of bacterial pneumonia at intensive care unit (ICU) admission would be a useful stewardship tool. We performed a multicenter observational study including 331 COVID-19 patients requiring invasive mechanical ventilation at ICU admission; 179 patients with bacterial pneumonia; and 152 displaying negative lower-respiratory samplings. A multivariable logistic regression model was built to identify predictors of pulmonary co-infections, and a composite risk score was developed using β-coefficients. We identified seven variables as predictors of bacterial pneumonia: vaccination status (OR 7.01; 95% CI, 1.73-28.39); chronic kidney disease …
Intimate Partner Violence Screening In The Emergency Department, Rebecca Stuerman
Intimate Partner Violence Screening In The Emergency Department, Rebecca Stuerman
Dissertations
Problem: Intimate partner violence [IPV] is a public health concern that affects one in three women worldwide. IPV can be addressed through identification and early intervention with minimal risk to the patient. The emergency department is an important setting for screening given the frequency with which people who experience abuse may present with IPV-related injuries and other related concerns (depression, suicidality, etc.). Successfully implementing a validated tool for screening and providing early access to resources and referrals may help to mitigate the longterm negative impacts of IPV. The need for increased staff education was a major barrier to screening for …
Encouraging Human Papillomavirus Vaccine Uptake: A Healthcare Improvement Project, Lauren E. Woll
Encouraging Human Papillomavirus Vaccine Uptake: A Healthcare Improvement Project, Lauren E. Woll
Dissertations
Abstract
Problem: Human papillomaviruses are the causative agents of >95% of cervical cancers, most oropharyngeal and anogenital cancers, yet the vaccination status of the population remains critically low despite Gardasil9 offering robust protection against HPV-related disease.
Methods: This quality improvement project utilized a descriptive, observational design to assess the effect of the HPV Encouragement Bundle, a two-step intervention to improve HPV vaccine uptake. Quantitative data was collected via retrospective chart review to assess the effect of the intervention on first-dose administration of Gardasil9 (series initiation), as well as overall Gardasil9 vaccine uptake.
Results: Following implementation, Gardasil9 first dose uptake increased …
Determinants Of Covid-19 Vaccination Decision-Making Behaviors Among Pregnant Women In Sub-Saharan Africa: A Scoping Review, Christine Markham
Determinants Of Covid-19 Vaccination Decision-Making Behaviors Among Pregnant Women In Sub-Saharan Africa: A Scoping Review, Christine Markham
Faculty, Staff and Student Publications
Despite the availability of the coronavirus disease 2019 (COVID-19) vaccination, uptake among pregnant women in Sub-Saharan Africa has been low. This scoping review aimed to identify and characterize determinants influencing COVID-19 vaccination decision-making behaviors among pregnant women in Sub-Saharan Africa. We searched five online databases for articles on COVID-19 vaccination among pregnant women in Sub-Saharan Africa. We identified studies published in English between March 2020 and April 2023 that assessed vaccine-specific issues, psychosocial constructs, and contextual factors associated with COVID-19 vaccination decision-making behaviors. Of the fourteen studies identified, over half (57.1%) were cross-sectional; three used qualitative research methods; and three …
Is The Public Aware Of Water Quality Monitoring And Safety Notifications On Beaches?, Asli Aslan, Jeffery A. Jones, Dziyana Nazaruk, Sibel Zeki
Is The Public Aware Of Water Quality Monitoring And Safety Notifications On Beaches?, Asli Aslan, Jeffery A. Jones, Dziyana Nazaruk, Sibel Zeki
Journal of the Georgia Public Health Association
Recreational water-related activities have important public health benefits, however, pollution at beaches may have serious health risks. Although there is a substantial amount of research and policies in place at federal and state levels, oftentimes these efforts may not be well translated to the public. This paper evaluates the effectiveness of routine water quality monitoring and warning systems in Georgia, USA. A survey was conducted among 238 beachgoers in Georgia, asking about awareness of water quality monitoring and warning signs for beach advisories. Surveys were collected directly at beaches as well as through an online questionnaire. Results show that more …
Transformative Approach To Developing A Sustainable Interprofessional Education Program, Tilicia Mayo-Gamble, Jane Nester, Paula Tillman, Sandhya Lohani, Padmini Shankar, Pamela Mahan
Transformative Approach To Developing A Sustainable Interprofessional Education Program, Tilicia Mayo-Gamble, Jane Nester, Paula Tillman, Sandhya Lohani, Padmini Shankar, Pamela Mahan
Journal of the Georgia Public Health Association
Background: The ability to offer and sustain interprofessional collaboration and education (IPE) in an academic setting could potentially serve as a training model for other academic institutions to implement programs that will increase the number of practice-ready, culturally competent healthcare professionals. We designed, implemented, and evaluated an Area Health Education Center (AHEC) Scholars Program to train culturally competent interdisciplinary students to provide quality, patient-centered healthcare in rural and underserved communities post-graduation.
Methods: Two cohorts of students (Cohort 1, n = 15, Cohort 2, n = 14) were recruited into a two-year longitudinal program with 80 hours of didactic learning and …
Community Centred Co-Design Methodology For Designing And Implementing Socio-Behavioural Interventions To Counter Covid-19 Related Misinformation Among Marginalized Population Living In The Squatter Settlements Of Karachi, Pakistan: A Methodology Paper, Rubina Qasim, Waqas Ahmed Farooqui, Atiya Rahman, Rukhsana Haroon, Madiha Saleem, Muhammad Rafique, Fiza Noor, Afifa Ghani, Muhammad Yaqoob, Mohammad Tahir Yousafzai
Community Centred Co-Design Methodology For Designing And Implementing Socio-Behavioural Interventions To Counter Covid-19 Related Misinformation Among Marginalized Population Living In The Squatter Settlements Of Karachi, Pakistan: A Methodology Paper, Rubina Qasim, Waqas Ahmed Farooqui, Atiya Rahman, Rukhsana Haroon, Madiha Saleem, Muhammad Rafique, Fiza Noor, Afifa Ghani, Muhammad Yaqoob, Mohammad Tahir Yousafzai
Community Health Sciences
Background: Misinformation regarding COVID-19 pandemic and vaccination is damaging COVID-19 vaccine trust and acceptance in Low- and Middle-Income Countries (LMIC). Identification of misinformation and designing locally acceptable solutions are needed to improve COVID-19 vaccine acceptance. This study aimed to utilize community-led co-design methodology to evaluate misinformation regarding COVID-19 and develop contextual interventions to address misinformation in a marginalized peri urban slum communities of Landhi town Karachi, Pakistan.
Methods: This study was conducted between January and December 2021, in marginalized peri-urban slum dwellers of Muslimabad Colony, Landhi Town Karachi, Pakistan. We used a community-centred co-design methodology embedded within mixed study design …
The Impact Of Covid-19 On The Financial Performance Of Largest Teaching Hospitals, Tiffany Champagne-Langabeer, James R Langabeer
The Impact Of Covid-19 On The Financial Performance Of Largest Teaching Hospitals, Tiffany Champagne-Langabeer, James R Langabeer
Faculty, Staff and Student Publications
The COVID-19 pandemic disrupted hospital operations. Anecdotal evidence suggests financial performance likewise suffered, yet little empirical research supports this claim. This study aimed to explore the impact of the pandemic on the financial performance of the most prominent academic hospitals in the United States. Data from the 115 largest major teaching hospitals in the United States were extracted from the American Hospital Directory for three years (2019-2021). We hypothesized that the year and region would moderate the relationship between a hospital's return on assets (financial performance) and specific operational variables. We found evidence through descriptive statistics and multivariate moderated regressions …
Applying Customer Discovery Method To A Chronic Disease Self-Management Mobile App: Qualitative Study, Nallely Mora, Zoe Arvanitakis, Merly Thomas, Holly Kramer, Elaine H. Morrato, Talar W. Markossian
Applying Customer Discovery Method To A Chronic Disease Self-Management Mobile App: Qualitative Study, Nallely Mora, Zoe Arvanitakis, Merly Thomas, Holly Kramer, Elaine H. Morrato, Talar W. Markossian
Parkinson School of Health Sciences and Public Health
Background: A significant health challenge is evident in the United States, with 6 in 10 adults having a chronic disease and 4 in 10 adults having 2 or more. Chronic disease self-management aims to prevent or delay disease progression and disability and reduce mortality risk. The evidence to support the use of information technology tools, including mobile apps, web-based portals, and web-based educational interventions, that support disease self-management and improve clinical outcomes is growing. Customer discovery and value proposition design methodology is a form of stakeholder engagement and is based on marketing and lean start-up business methods. As applied in …
Differentials And Predictors Of Food Insecurity Among Federally Qualified Health Center Target Populations In Philadelphia: A Cross-Sectional Study, Galicano Kai Inguito, Brandon Joa, James Gardner, Eric N Fung, Laura Layer, Karen Fritz
Differentials And Predictors Of Food Insecurity Among Federally Qualified Health Center Target Populations In Philadelphia: A Cross-Sectional Study, Galicano Kai Inguito, Brandon Joa, James Gardner, Eric N Fung, Laura Layer, Karen Fritz
Department of Medicine Faculty Papers
BACKGROUND: Over the past decade, the prevalence of food insecurity declined in the United States but curiously climbed in Philadelphia, Pennsylvania, a sizable metropolitan area where many households experience food insecurity and are dependent on programs like SNAP. Therefore, we aimed to determine the burden of food insecurity among populations near Philadelphia Federally Qualified Health Center (FQHC) clinic sites.
METHODS: This cross-sectional study was conducted in North Philadelphia, a populous and impoverished section of Philadelphia with many zip codes reporting 30-45% or more of the population below the federal poverty line. Students and clinicians affiliated with a local FQHC conducted …
Unmasking Structural Racism In U.S. Medical Education: Advancing Equity For Underrepresented Medical Students, Daryl O. Traylor, Eboni E. Anderson, Destiney Kirby, Asia Nichole Hodges, Brianna Clark, Stephen Sinatra Jr.
Unmasking Structural Racism In U.S. Medical Education: Advancing Equity For Underrepresented Medical Students, Daryl O. Traylor, Eboni E. Anderson, Destiney Kirby, Asia Nichole Hodges, Brianna Clark, Stephen Sinatra Jr.
Journal of Social, Behavioral, and Health Sciences
The COVID pandemic cast a harsh light on the structural and systemic health inequalities that exist in American society and in U.S. medical education. Black and Brown communities were disproportionately affected, and the pandemic highlighted the need for a diverse physician and healthcare workforce. Both the lack of equitable, high-quality healthcare in underrepresented communities and the obstacles that students who are underrepresented in medicine (URiM) experience in medical school are direct consequences of the structural racism that flourishes in U.S. medical schools and healthcare institutions. In this article, we explain structural racism and how it has manifested itself in medical …
Effect Of Reduced Versus Usual Lipid Emulsion Dosing On Bilirubin Neurotoxicity And Neurodevelopmental Impairment In Extremely Preterm Infants: Study Protocol For A Randomized Controlled Trial, Eric W Reynolds, Andrew H Huber, Matthew A Rysavy, Maria Del Mar Romero Lopez, Amir M Khan
Effect Of Reduced Versus Usual Lipid Emulsion Dosing On Bilirubin Neurotoxicity And Neurodevelopmental Impairment In Extremely Preterm Infants: Study Protocol For A Randomized Controlled Trial, Eric W Reynolds, Andrew H Huber, Matthew A Rysavy, Maria Del Mar Romero Lopez, Amir M Khan
Faculty, Staff and Student Publications
BACKGROUND: Bilirubin neurotoxicity (BN) occurs in premature infants at lower total serum bilirubin levels than term infants and causes neurodevelopmental impairment. Usual dose lipid infusions in preterm infants may increase free fatty acids sufficiently to cause bilirubin displacement from albumin, increasing passage of unbound bilirubin (UB) into the brain leading to BN and neurodevelopmental impairment not reliably identifiable in infancy. These risks may be influenced by whether cycled or continuous phototherapy is used to control bilirubin levels.
OBJECTIVE: To assess differences in wave V latency measured by brainstem auditory evoked responses (BAER) at 34-36 weeks gestational age in infants born …
Development Of A Covid-19 Vulnerability Index (Cvi) For The Counties And Residents Of New Jersey, Usa., Remo Disalvatore, Sarah K Bauer, Jeong Eun Ahn, Kauser Jahan
Development Of A Covid-19 Vulnerability Index (Cvi) For The Counties And Residents Of New Jersey, Usa., Remo Disalvatore, Sarah K Bauer, Jeong Eun Ahn, Kauser Jahan
Henry M. Rowan College of Engineering Departmental Research
The coronavirus disease 2019, or COVID-19, has impacted countless aspects of everyday life since it was declared a global pandemic by the World Health Organization in March of 2020. From societal to economic impacts, COVID-19 and its variants will leave a lasting impact on our society and the world. During the height of the pandemic, it became increasingly evident that indices, such as the Center for Disease Control's (CDC) Social Vulnerability Index (SVI), were instrumental in predicting vulnerabilities within a community. The CDC's SVI provides important estimates on which communities will be more susceptible to 'hazard events' by compiling a …
Effect Of Total Population, Population Density And Weighted Population Density On The Spread Of Covid-19 In Malaysia, Hui Shan Wong, Md Zobaer Hasan, Omar Sharif, Azizur Rahman
Effect Of Total Population, Population Density And Weighted Population Density On The Spread Of Covid-19 In Malaysia, Hui Shan Wong, Md Zobaer Hasan, Omar Sharif, Azizur Rahman
School of Mathematical & Statistical Sciences Faculty Publications
Since November 2019, most countries across the globe have suffered from the disastrous consequences of the Covid-19 pandemic which redefined every aspect of human life. Given the inevitable spread and transmission of the virus, it is critical to acknowledge the factors that catalyse transmission of the disease. This research investigates the relation of the external demographic parameters such as total population, population density and weighted population density on the spread of Covid-19 in Malaysia. Pearson correlation and simple linear regression were utilized to identify the relation between the population-related variables and the spread of Covid-19 in Malaysia using data from …
The Relationship Between Changes In Neighborhood Physical Environment And Changes In Physical Activity Among Children: A Prospective Cohort Study, Francesco Acciai, Robin S Deweese, Kristen Lloyd, Michael J Yedidia, Michelle Kennedy, Katherine Isselmann Disantis, David Tulloch, Punam Ohri-Vachaspati
The Relationship Between Changes In Neighborhood Physical Environment And Changes In Physical Activity Among Children: A Prospective Cohort Study, Francesco Acciai, Robin S Deweese, Kristen Lloyd, Michael J Yedidia, Michelle Kennedy, Katherine Isselmann Disantis, David Tulloch, Punam Ohri-Vachaspati
College of Population Health Faculty Papers
BACKGROUND: Physical activity (PA) is associated with positive health outcomes over the entire life course. Many community-based interventions that promote PA focus on implementing incremental changes to existing facilities and infrastructure. The objective of this study was to determine if such upgrades were associated with increases in children's PA.
METHODS: Two cohorts of 3- to 15-year-old children (n = 599) living in 4 low-income New Jersey cities were followed during 2- to 5-year periods from 2009 to 2017. Data on children's PA were collected at 2 time points (T1 and T2) from each cohort using telephone survey of parents; data …
Michigancovid19outbreakreportcollection, Michigan Department Of Health & Human Services
Michigancovid19outbreakreportcollection, Michigan Department Of Health & Human Services
Michigan COVID-19 Outbreak Reports
This is a zipped file of all the pdfs uploaded to this collection, spanning from 2020-08-20 through 2023-04-27 for the overall outbreak reports, 2020-09-14 through 2022-06-13 for school outbreak reports, and 2022-06-21 through 2023-04-25 for ISD K-12 outbreak reports.
The zip file also includes a comma separated file that lists the metadata for each file, including the file name within the Michigan COVID-19 Outbreak Reports ScholarWorks Collection (ScholarWorksFileTitle), the archived URL (InternetArchiveLink), the description of the file within the Michigan COVID-19 Outbreak Reports ScholarWorks Collection (ScholarWorksAbstract), and any additional comments about the file within the Michigan COVID-19 Outbreak Reports ScholarWorks …
Michigancovid19vaccinecollection, Michigan Department Of Health & Human Services
Michigancovid19vaccinecollection, Michigan Department Of Health & Human Services
Michigan COVID-19 Vaccine Data
This is a zipped file of all the pdfs uploaded to this collection, spanning from 2020-12-16 through 2023-04-26. It also includes a few additional pdfs: 2020-10-16_Michigan_COVIDVaccination_Plan.pdf; 2020-12-13_Michigan_COVIDVaccination_PrioritizationGuidance.pdf; 2020-12-13_Michigan_COVIDVaccine_FAQ.pdf; 2020-12-13_Michigan_COVIDVaccine_Infograph.pdf; 2021-01-21_Michigan_COVIDVaccine_Locations.pdf.
The zip file also includes a comma separated file that lists the metadata for each file, including the file name within the Michigan COVID-19 Vaccine Data ScholarWorks Collection (ScholarWorksFileTitle), the archived URL (InternetArchiveLink), the description of the file within the Michigan COVID-19 Vaccine Data ScholarWorks Collection (ScholarWorksAbstract), and any additional comments about the file within the Michigan COVID-19 Vaccine Data ScholarWorks Collection (ScholarWorksComments).
Simulation As A Key Training Method For Inculcating Public Health Leadership Skills: A Mixed Methods Study, Keren Dopelt, Itamar Shevach, Ofek Eliad Vardimon, Katarzyna Czabanowska, Jascha De Nooijer, Robert Otok, Lore Leighton, Osnat Bashkin, Mariusz Duplaga, Hagai Levine, Fiona Macleod, Maureen Malowany, Leah Okenwa-Emegwa, Shira Zelber-Sagi, Nadav Davidovitch, Paul Barach
Simulation As A Key Training Method For Inculcating Public Health Leadership Skills: A Mixed Methods Study, Keren Dopelt, Itamar Shevach, Ofek Eliad Vardimon, Katarzyna Czabanowska, Jascha De Nooijer, Robert Otok, Lore Leighton, Osnat Bashkin, Mariusz Duplaga, Hagai Levine, Fiona Macleod, Maureen Malowany, Leah Okenwa-Emegwa, Shira Zelber-Sagi, Nadav Davidovitch, Paul Barach
College of Population Health Faculty Papers
BACKGROUND: Successful management of public health challenges requires developing and nurturing leadership competencies. We aimed to evaluate the effectiveness of training simulations to assess public health leadership and decision-making competencies during emergencies as an effective learning and training method.
METHODS: We examined the effects of two simulation scenarios on public health school students in terms of their experience (compared to face-to-face learning) and new skills acquired for dealing with similar emergent situations in the future. A mixed-methods design included developing a validated and pre-tested questionnaire with open-and closed-ended questions that examined the simulation impact and the degree of student satisfaction …
Adaptation Of A Community Health Outreach Model During The Covid-19 Pandemic: The Case Of The Mexican Consulates In The United States Of America, Pablo Gaitán-Rossi, Mireya Vilar-Compte, Arturo Vargas Bustamante
Adaptation Of A Community Health Outreach Model During The Covid-19 Pandemic: The Case Of The Mexican Consulates In The United States Of America, Pablo Gaitán-Rossi, Mireya Vilar-Compte, Arturo Vargas Bustamante
Department of Public Health Scholarship and Creative Works
The Ventanillas de Salud (VDS – “Health Windows”) are a culturally sensitive outreach program within the 49 Mexican Consulates in the United States that provides information and health care navigation support to underserved and uninsured Mexican immigrants. During the COVID-19 pandemic the VDS rapidly transitioned to remote operations adding new services. Based on the EquIR implementation framework, this qualitative study investigates how adaptations to improve emergency preparedness were performed. We conducted motivational interviews with three actors – six VDS coordinators, eight partner organizations, and ten VDS users– in two VDS, Los Angeles and New York, to document specific needs of …
Phase Ii Trial Of Medi0457 And Durvalumab For Patients With Recurrent/Metastatic Human Papillomavirus-Associated Cancers, Van K Morris, Amir Jazaeri, Shannon N Westin, Curtis Pettaway, Solly George, Michaela Grinsfelder, Benny Johnson, David Vining, Ming Guo, Bryan Fellman, Michael Frumovitz
Phase Ii Trial Of Medi0457 And Durvalumab For Patients With Recurrent/Metastatic Human Papillomavirus-Associated Cancers, Van K Morris, Amir Jazaeri, Shannon N Westin, Curtis Pettaway, Solly George, Michaela Grinsfelder, Benny Johnson, David Vining, Ming Guo, Bryan Fellman, Michael Frumovitz
Faculty, Staff and Student Publications
BACKGROUND: Human papillomavirus (HPV) types 16/18 drive oncogenesis for most patients with cervical, anal, and penile cancers. MEDI0457, a therapeutic DNA vaccine containing plasmids for E6 and E7 HPV-16/18 viral oncogenes and IL-12 adjuvant, is safe and provokes an immune response against E6/E7. We tested MEDI0457 with the anti-PD-L1 antibody durvalumab for patients with HPV-associated cancers.
METHODS: Patients with recurrent/metastatic, treatment-refractory HPV-16/18 cervical cancer, or rare HPV-associated (anal and penile) cancers were eligible. Prior immune checkpoint inhibition was not permitted. Patients received MEDI0457 7 mg intramuscularly (weeks 1, 3, 7, 12, and every 8 weeks thereafter) and durvalumab 1500 mg …
A Descriptive, Multi-Site Case Study To Discover The Inclusion Of Disability Competencies In Undergraduate Public Health Program Curricula In California-Based Public Universities, Jacqueline Suzanne Siukola Tompkins
A Descriptive, Multi-Site Case Study To Discover The Inclusion Of Disability Competencies In Undergraduate Public Health Program Curricula In California-Based Public Universities, Jacqueline Suzanne Siukola Tompkins
Doctoral Dissertations and Projects
Nearly one in four adults and one in six children in the United States (U.S.) have a disability. Despite the evidence documenting health differences, public health professionals receive inconsistent or little-to-no disability education in graduate public health curricula. Undergraduate public health (UGPH) programs have an expanding role in building the future public health workforce, including the U.S. governmental public health workforce. However, the inclusion of disability-related content within UGPH program curricula is currently unknown. The purpose of this multi-site case study was to conduct preliminary research to describe how disability-related curricula are or can be included in UGPH program curricula …
Current Oral Hygiene And Recreational Behavioral Trends In Hiv Disease, Donald E. Mercante, Emily Guarisco, Elizabeth A. Lilly, Arni Rao, Kelly Treas, Clifford J. Beall, Zach Thompson, Ann L. Griffen, Eugene J. Leys, Jose A. Vazquez, Michael E. Hagensee, Paul L. Fidel
Current Oral Hygiene And Recreational Behavioral Trends In Hiv Disease, Donald E. Mercante, Emily Guarisco, Elizabeth A. Lilly, Arni Rao, Kelly Treas, Clifford J. Beall, Zach Thompson, Ann L. Griffen, Eugene J. Leys, Jose A. Vazquez, Michael E. Hagensee, Paul L. Fidel
School of Dentistry Faculty Publications
Objective: HIV disease is evolving with more HIV+ persons experiencing a high quality of life with well-controlled viremia. We recently enrolled a large cohort of HIV+ and clinically relevant HIV− persons for oral microbiome analyses that included a questionnaire related to oral hygiene and recreational behaviors. Here, the questionnaire responses were analyzed for behavioral trends within the cohort, together with trends over time by comparison to a previous geographically centered HIV+ cohort. Methods: Data were collected by questionnaire at baseline visits as cross-sectional assessments. Multivariable analyses were conducted for associations of HIV status as well as age, race, and sex, …
Guiding Post-Hospital Recovery By 'What Matters:' Implementation Of Patient Priorities Identification In A Va Community Living Center, Erica Martinez
Guiding Post-Hospital Recovery By 'What Matters:' Implementation Of Patient Priorities Identification In A Va Community Living Center, Erica Martinez
Faculty, Staff and Student Publications
BACKGROUND: Patient priorities care (PPC) is an effective age-friendly health systems (AFHS) approach to aligning care with goals derived from 'what matters'. The purpose of this quality improvement program was to evaluate the fidelity and feasibility of the health priorities identification (HPI) process in VA Community Living Centers (CLC).
METHODS: PPC experts worked with local CLC staff to guide the integration of HPI into the CLC and utilized a Plan-Do-Study-Act (PDSA) model for this quality improvement project. PPC experts reviewed health priorities identification (HPI) encounters and interdisciplinary team (IDT) meetings for fidelity to the HPI process of PPC. Qualitative interviews …
Response To "Department Of Commerce, National Institute Of Standards And Technology, Agency Information Collection Activities", Fred D. Ledley
Response To "Department Of Commerce, National Institute Of Standards And Technology, Agency Information Collection Activities", Fred D. Ledley
CISI Publication
This response supports the recommendations of the interagency working group for Bayh-Dole that the dataset collected and archived in iEdison “…be amended and expanded so that the agencies could get a clear picture of the commercialization plans for subject inventions, what the licensing landscape looked like, (and) what products were resulting, …”
Our comments are informed by several recent studies describing the effectiveness and reach of the Bayh-Dole Act in promoting and protecting the public interest in practical applications of government-funded biomedical research to pharmaceutical innovations.
Trends And Seasonality Of Emergency Department Visits And Hospitalizations For Suicidality Among Children And Adolescents In The Us From 2016 To 2021
Faculty, Staff and Student Publications
IMPORTANCE: The detection of seasonal patterns in suicidality should be of interest to clinicians and US public health officials, as intervention efforts can benefit by targeting periods of heightened risk.
OBJECTIVES: to examine recent trends in suicidality rates, quantify the seasonality in suicidality, and demonstrate the disrupted seasonality patterns during the spring 2020 COVID-19-related school closures among US children and adolescents.
DESIGN, SETTING, AND PARTICIPANTS: This population-based, descriptive cross-sectional study used administrative claims data from Optum's deidentifed Clinformatics Data Mart Database. Participants included children aged 10 to 12 years and adolescents aged 13 to 18 years who were commercially insured …
Clinical And Demographic Factors Associated With Covid-19, Severe Covid-19, And Sars-Cov-2 Infection In Adults: A Secondary Cross-Protocol Analysis Of 4 Randomized Clinical Trials, Madhu Choudhary, Samuel T Robinson, Peter B Gilbert, Dean Follmann, Holly Janes, James G Kublin, Lindsey R Baden, Paul Goepfert, Glenda E Gray, Beatriz Grinsztejn, Karen L Kotloff, Cynthia L Gay, Brett Leav, Jacqueline Miller, Ian Hirsch, Jerald Sadoff, Lisa M Dunkle, Kathleen M Neuzil, Lawrence Corey, Ann R Falsey, Hana M El Sahly, Magdalena E Sobieszczyk, Yunda Huang
Clinical And Demographic Factors Associated With Covid-19, Severe Covid-19, And Sars-Cov-2 Infection In Adults: A Secondary Cross-Protocol Analysis Of 4 Randomized Clinical Trials, Madhu Choudhary, Samuel T Robinson, Peter B Gilbert, Dean Follmann, Holly Janes, James G Kublin, Lindsey R Baden, Paul Goepfert, Glenda E Gray, Beatriz Grinsztejn, Karen L Kotloff, Cynthia L Gay, Brett Leav, Jacqueline Miller, Ian Hirsch, Jerald Sadoff, Lisa M Dunkle, Kathleen M Neuzil, Lawrence Corey, Ann R Falsey, Hana M El Sahly, Magdalena E Sobieszczyk, Yunda Huang
Faculty, Staff and Student Publications
IMPORTANCE: Current data identifying COVID-19 risk factors lack standardized outcomes and insufficiently control for confounders.
OBJECTIVE: To identify risk factors associated with COVID-19, severe COVID-19, and SARS-CoV-2 infection.
DESIGN, SETTING, AND PARTICIPANTS: This secondary cross-protocol analysis included 4 multicenter, international, randomized, blinded, placebo-controlled, COVID-19 vaccine efficacy trials with harmonized protocols established by the COVID-19 Prevention Network. Individual-level data from participants randomized to receive placebo within each trial were combined and analyzed. Enrollment began July 2020 and the last data cutoff was in July 2021. Participants included adults in stable health, at risk for SARS-CoV-2, and assigned to the placebo group …
Unmet Needs And Coping Strategies Of Older Underserved Veterans During The Covid-19 Pandemic, Trenton M. Haltom, Joyce Tiong, Tracy L. Evans, Nipa Kamdar, Gala True, Mark E. Kunik
Unmet Needs And Coping Strategies Of Older Underserved Veterans During The Covid-19 Pandemic, Trenton M. Haltom, Joyce Tiong, Tracy L. Evans, Nipa Kamdar, Gala True, Mark E. Kunik
School of Medicine Faculty Publications
Introduction: The COVID-19 pandemic has had profound impacts on people with diabetes, a group with high morbidity and mortality. Factors like race, age, income, Veteran-status, and limited or interrupted resources early in the COVID-19 pandemic compounded risks for negative health outcomes. Our objective was to characterize the experiences and needs of under-resourced Veterans with type 2 diabetes during the COVID-19 pandemic. Methods: We conducted semi-structured qualitative interviews (March through September 2021) with U.S. military Veterans with diabetes. Transcripts were analyzed using a team-based, iterative process of summarizing and coding to identify key themes. Participants included Veterans (n = 25) who …
Why The West Should Help China Reduce Unrecognized And Preventable Covid-19 Deaths, George A. Gellert
Why The West Should Help China Reduce Unrecognized And Preventable Covid-19 Deaths, George A. Gellert
Journal of Health Ethics
In an era marked by a ruinous war between a democratic state and a totalitarian regime, political volatility, rightward looking isolationism and nationalism, and heightened competition and disputes between China and the West, it is perhaps difficult to discern why the West should supply China with COVID-19 vaccines and therapeutics, as well as epidemiological assistance in order to mitigate a potentially unrecognized COVID-19 crisis in that nation. This commentary considers three arguments against Western and international indifference to the plight of China as it transitions to COVID-19 endemicity.
Ethical Considerations Surrounding Vaccine Development During A Public Health Crisis, Syed Arsalan Akhter Zaidi, Kainat Saleem, Rahul Bollam, Bushra Zaidi
Ethical Considerations Surrounding Vaccine Development During A Public Health Crisis, Syed Arsalan Akhter Zaidi, Kainat Saleem, Rahul Bollam, Bushra Zaidi
Journal of Health Ethics
Epidemics and Pandemics have been plaguing mankind since many centuries, and are a cause of major healthcare expense in modern times. The novel coronavirus pandemic of 2019-2020 spread worldwide faster than many previous pandemics, including EBOLA in 2017. Although personal protective equipment, and social distancing slowed the outbreak, a vaccine is needed to ensure global immunization and to stop this deadly outbreak. Developing a vaccine in times of a public health crisis comes with a lot of ethical considerations, including overlooking proper informed consent, the issue of using placebo in control arm of trials, extended timelines of development of vaccines, …
A Framework For Personal Respiratory Ethics, Ian W. Goddard
A Framework For Personal Respiratory Ethics, Ian W. Goddard
Journal of Health Ethics
The Covid-19 pandemic raises the need for an ethical framework that addresses the unique ethical challenges and questions arising from airborne infectious diseases. For example, are we ever ethically obliged to wear a face mask? If so, why and when? The Respiratory Ethics Framework (REF) herein proposes pathways to answers grounded in ethical norms and the moral principles of non-harm, beneficence and respect for personal autonomy. REF is a personal ethics wherein your ethical duty to increase your respiratory hygiene efforts—such as by donning a mask—is proportional to your estimation of an increase in the likelihood that your respiratory effluent …