Medicine and Health Sciences Commons^™

Childhood Dairy Consumption Is Associated With Lower Age Of Menarche In A National Representative Sample Of Us Women, Jacqueline Vernarelli, Sara Szollosy

Public Health Faculty Publications

Background and aims: Breast cancer is the most prevalent cancer and leader in cancer-related deaths among women with a variety of established risk factors.

Methods Data from a nationally representative sample of 5,574 women who participated in the 2015–2018 NHANES was used to evaluate the correlation of childhood and adolescent dairy milk consumption and age of menarche. Reproductive history was asked of women > 12y. Data regarding dairy consumption between the ages of 5–12 was available for women > 20y. Survey regression models were used to calculate adjusted age of menarche for categories of dairy consumption after adjusting for relevant confounders.

Results …

Prevalence Trend And Disparities In Rheumatoid Arthritis Among Us Adults, 2005–2018, Yingke Xu, Qing Wu

Public Health Faculty Publications

Rheumatoid arthritis (RA) trends among US adults and disparities in RA patients in recent years have not been well described. We aimed to examine the trend of RA prevalence and disparities among US adults. Data from the National Health and Nutrition Examination Survey (NHANES) of the years 2005–2018 were analyzed to examine the self-reported RA prevalence trend. Age-adjusted RA prevalence stratified by race/ethnicity and socioeconomic status (SES), as well as associated linear trends, were calculated for both genders. The multivariable adjustment was used to evaluate the association between race, SES, and RA. During 2005–2018, there was no significant linear trend …

Lagged Meteorological Impacts On Covid-19 Incidence Among High-Risk Counties In The United States—A Spatiotemporal Analysis, Lung-Chang Chien, Lung-Wen Antony Chen, Ro-Ting Lin

Public Health Faculty Publications

Background: The associations between meteorological factors and coronavirus disease 2019 (COVID-19) have been discussed globally; however, because of short study periods, the lack of considering lagged effects, and different study areas, results from the literature were diverse and even contradictory. Objective: The primary purpose of this study is to conduct more reliable research to evaluate the lagged meteorological impacts on COVID-19 incidence by considering a relatively long study period and diversified high-risk areas in the United States. Methods: This study adopted the distributed lagged nonlinear model with a spatial function to analyze COVID-19 incidence predicted by multiple meteorological measures from …

Utility Of Multi-Theory Model (Mtm) To Explain The Intention For Pap Adherence In Newly Diagnosed Sleep Apnea Patients, Manoj Sharma, Anuj Chandra, Ryan Toth, Vinayak K. Nahar

Public Health Faculty Publications

Purpose: The objective of this study was to assess the utility of a fourth-generation multi-theory model (MTM) in explaining the intention for initiation and sustenance of PAP adherence among newly diagnosed sleep apnea patients.
Patients and Methods: For this cross-sectional study, data were collected at a private sleep center located in the Southeastern United States. A total of 138 newly diagnosed patients with sleep apnea who had been prescribed PAP therapy completed a valid and reliable 41-item MTM instrument. Stepwise multiple regression modeling was conducted to assess MTM based explanatory variables of PAP adherence in this study sample.
Results: MTM …

Trends In Osteoporosis And Mean Bone Density Among Type 2 Diabetes Patients In The Us From 2005 To 2014, Yingke Xu, Qing Wu

Public Health Faculty Publications

© 2021, The Author(s). This study aimed to examine how bone health changed among T2DM patients in the past decade. Continuous National Health and Nutrition Examination Survey (NHANES) data from 2005–2006 to 2013–2014 were analyzed to examine the trends of bone mineral density (BMD) and the prevalence trends of osteoporosis osteopenia among T2DM patients and non-diabetic people aged 40 years and older. The age- and BMI-adjusted mean BMD of the femur neck for the four NHANES cycles decreased linearly in both T2DM patients and non-diabetic people (both Plinear trend ≤ 0.009). Among women with T2DM, the mean BMD in 2013–2014 …

The Utility Of Genetic Risk Score To Improve Performance Of Frax For Fracture Prediction In Us Postmenopausal Women, Xiangxue Xiao, Qing Wu

Public Health Faculty Publications

The ability of the fracture risk assessment tool (FRAX) in discriminating fracture and non-fracture in postmenopausal women remains suboptimal. Adding a genetic profile may improve the performance of FRAX. Three genetic risk scores (GRSs) (GRS_fracture, GRS_BMD, GRS_eBMD) were calculated for each participant in the Women’s Health Initiative Study (n = 23,981), based on the summary statistics of three comprehensive osteoporosis-related genome-wide association studies (GWAS). The primary outcomes were incident major osteoporotic fracture (MOF) and hip fracture (HF). The association between each GRS and fracture risk were evaluated in separate Cox Proportional Hazard models, with FRAX clinical risk factors adjusted for. …

Flame Retardants And Neurodevelopment: An Updated Review Of Epidemiological Literature, Ann M. Vuong, Kimberly Yolton, Kim M. Cecil, Joseph M. Braun, Bruce P. Lanphear, Aimin Chen

Public Health Faculty Publications

Purpose of Review: Flame retardant (FR) compounds can adversely impact neurodevelopment. This updated literature review summarizes epidemiological studies of FRs and neurotoxicity published since 2015, covering historical (polybrominated biphenyls [PBBs], polychlorinated biphenyls [PCBs]), contemporary (polybrominated diphenyl ethers [PBDEs], hexabromocyclododecane [HBCD], and tetrabromobisphenol A [TBBPA]), and current-use organophosphate FRs (OPFRs) and brominated FRs (2-ethylhexyl 2,3,4,5-tetrabromobezoate [EH-TBB] TBB), bis(2-ethylhexyl) tetrabromophthalate [BEH-TEBP]), focusing on prenatal and postnatal periods of exposure. Recent Findings: Continuing studies on PCBs still reveal adverse associations with child cognition and behavior. Recent studies indicate PBDEs are neurotoxic, particularly for gestational exposures with decreased cognition and increased externalizing behaviors. Findings …

Improving Healthcare Quality In The United States Healthcare System: A Scientific Management Approach, Soumya Upadhyay, William Opoku-Agyeman

Public Health Faculty Publications

The US healthcare system has been facing pressures from stakeholders to reduce costs and improve quality. The purpose of this paper is to develop a conceptual model to illustrate the approaches used in healthcare quality management (Continuous Quality Improvement/Total Quality Management, Lean, and Six Sigma) weaved into the underlying framework of scientific management theory. This paper employs scientific management theory to explain the healthcare quality tenets that influence the quality of care in our healthcare organizations. The father of scientific management, Frederick Taylor, and other key contributors collectively created scientific management principles, which are widely used for quality improvement purposes …

Covid-19 And Mental Well-Being: Guidance On The Application Of Behavioral And Positive Well-Being Strategies, Amar Kanekar, Manoj Sharma

Public Health Faculty Publications

The raging COVID-19 pandemic has been a great source of anxiety, distress, and stress among the population. Along with mandates for social distancing and infection control measures, the growing importance of managing and cultivating good mental well-being practices cannot be disregarded. The purpose of this commentary is to outline and discuss some research-proven positive well-being and stress reduction strategies to instill healthy coping mechanisms among individuals and community members. The authors anticipate that usage of these strategies at the individual and the community level should greatly benefit the mental well-being not only in the current COVID-19 pandemic but also in …

Prevalence Of Depression, Anxiety, And Stress During Covid-19 Pandemic, Ram Lakhan, Amit Agrawal, Manoj Sharma

Public Health Faculty Publications

The coronavirus disease 2019 (COVID-19) crisis has greatly affected human lives across the world. Uncertainty and quarantine have been affecting people’s mental health. Estimations of mental health problems are needed immediately for the better planning and management of these concerns at a global level. A rapid scoping review was conducted to get the estimation of mental health problems in the COVID-19 pandemic during the first 7 months. Peer-reviewed, data-based journal articles published in the English language were searched in the PubMed, Medline, and Google Scholar electronic databases from December 2019 to June 2020. Papers that met the inclusion criteria were …

Correction To: Temporal Trend Of Research Related To Gun Violence From 1981 To 2018 In The United States: A Bibliometric Analysis, Lung-Chang Chien, Maxim Gakh, Courtney Coughenour, Ro-Ting Lin

Public Health Faculty Publications

No abstract provided.

Sociodemographic Determinants Of Physical Activity And Sport Participation Among Women In The United States, Jennifer R. Pharr, Nancy L. Lough, Angela M. Terencio

Public Health Faculty Publications

Regular physical activity and sport participation have been shown to improve women’s health; however, research has found that better health is associated with sport participation. Little is known about the sociodemographic determinants of physical activity among women, especially among the different subcategories of physical activity (sport, conditioning exercise, recreation, and household tasks). Because of the added health benefits associated with sport participation, the purpose of this study was to examine the sociodemographic determinants among subcategories of physically active women in the United States by analyzing Behavioral Risk Factor Surveillance System (BRFSS) data. We used data from the 2017 national BRFSS …

Opioid Use Disorders And Hospital Palliative Care Among Patients With Gastrointestinal Cancers: Ten-Year Trend And Associated Factors In The U.S. From 2005 To 2014, Jinwook Hwang, Jay J. Shen, Sun Jung Kim, Sung-Youn Chun, Pearl C. Kim, Se Won Lee, David Byun, Ji Won Yoo

Public Health Faculty Publications

This study aimed to analyze the trends of opioid use disorders, cannabis use disorders, and palliative care among hospitalized patients with gastrointestinal cancer and to identify their associated factors. We analyzed the National Inpatient Sample data from 2005 to 2014 and included hospitalized patients with gastrointestinal cancers. The trends of hospital palliative care and opioid or cannabis use disorders were analyzed using the compound annual growth rates (CAGR) with Rao-Scott correction for χ2 tests. Multivariate logistic regression analyses were performed to identify the associated factors. From 2005 to 2014, among 4,364,416 hospitalizations of patients with gastrointestinal cancer, the average annual …

Covid-19 Vulnerability Among People Who Use Drugs: Recommendations For Global Public Health Programmes And Policies, Ian W. Holloway, Anne C. Spaulding, Ayako Miyashita Ochoa, Laura A. Randall, Adrian R. King, The Hbou Study Team, Paula M. Frew

Public Health Faculty Publications

No abstract provided.

Regional Variation In States’ Naloxone Accessibility Laws In Association With Opioid Overdose Death Rates-Observational Study (Strobe Compliant), Hyo-Sun You, Jane Ha, Cyra-Y. Kang, Leeseul Kim, Jinah Kim, Jay J. Shen, Seong-Min Park, Sung-Youn Chun, Jinwook Hwang, Takashi Yamashita, Se Won Lee, Georgia Dounis, Yong-Jae Lee, Dong-Hun Han, David Byun, Ji Won Yoo, Hee-Taik Kang

Public Health Faculty Publications

Though overall death from opioid overdose are increasing in the United States, the death rate in some states and population groups is stabilizing or even decreasing. Several states have enacted a Naloxone Accessibility Laws to increase naloxone availability as an opioid antidote. The extent to which these laws permit layperson distribution and possession varies. The aim of this study is to investigate differences in provisions of Naloxone Accessibility Laws by states mainly in the Northeast and West regions, and the impact of naloxone availability on the rates of drug overdose deaths. This cross-sectional study was based on the National Vital …

Temporal Trend Of Research Related To Gun Violence From 1981 To 2018 In The United States: A Bibliometric Analysis, Lung-Chang Chien, Maxim Gakh, Courtney Coughenour, Ro-Ting Lin

Public Health Faculty Publications

Background: We aimed to evaluate the variation in gun violence-related research in the US over time to determine if there are meaningful changes in frequency of research at certain time points. Related publications were searched from the Web of Science. Methods: We searched articles from Web of Science to collect publication data of gun violence research in three disciplines (clinical sciences, life sciences, and social behavior sciences) from 1981 to 2018. The joinpoint regression approach was applied to evaluate the trend of publication ratio. We also adopted the generalized additive mixed model to compare the publication ratio among the three …

Learning From Transmasculine Experiences With Health Care: Tangible Inlets For Reducing Health Disparities Through Patient-Provider Relationships, Nickolas H. Lambrou, Katherine M. Cochran, Samantha Everhart, Jason D. Flatt, Megan Zuelsdorff, John B. O'Hara, Lance Weinhardt, Susan Flowers Benton, Carey E. Gleason

Public Health Faculty Publications

Purpose: We examined health care experiences of transmasculine young adults to clarify factors contributing to mistrust in the health care system and identify tangible and modifiable means to address health disparities through improved patient-provider interactions. Thematic analysis highlights patterns within historical relationships between medical models and transmasculine embodiment, and provides guidance for health care clinicians, researchers, and policy makers to deliver competent services for transgender and gender diverse (TGD) individuals. Methods: The study team used qualitative methodology guided by interpretive phenomenological analysis. Semistructured interviews with 12 participants who self-identified as transmasculine were conducted, transcribed, and coded thematically. Results: Participants were …

Factors Associated With Referring Close Contacts To An App With Individually-Tailored Vaccine Information, Matthew Z. Dudley, Rupali J. Limaye, Saad B. Omer, Sean T. O'Leary, Mallory K. Ellingson, Christine I. Spina, Sarah E. Brewer, Allison T. Chamberlain, Robert A. Bednarczyk, Fauzia Malik, Paula M. Frew, Daniel A. Salmon

Public Health Faculty Publications

Background: Infants too young to be fully vaccinated are vulnerable to potentially deadly influenza and pertussis infections. The cocooning strategy limits this risk by vaccinating those likely to interact with the infant and mother during this vulnerable time, such as close friends and family members. Distribution of accurate and accessible vaccine information through existing social networks could be an important tool in increasing vaccine confidence and coverage. Methods: We surveyed 1095 pregnant women from diverse prenatal care practices in Georgia and Colorado. These women were surveyed through a mobile app to assess vaccine intentions, attitudes, beliefs, norms, and levels of …

Short-Term Forecasts Of The Covid-19 Epidemic In Guangdong And Zhejiang, China: February 13–23, 2020, Kimberly Roosa, Yiseul Lee, Ruiyan Luo, Alexander Kirpich, Richard Rothenberg, J. M. Hyman, Ping Yan, Gerardo Chowell

Public Health Faculty Publications

The ongoing COVID-19 epidemic continues to spread within and outside of China, despite several social distancing measures implemented by the Chinese government. Limited epidemiological data are available, and recent changes in case definition and reporting further complicate our understanding of the impact of the epidemic, particularly in the epidemic’s epicenter. Here we use previously validated phenomenological models to generate short-term forecasts of cumulative reported cases in Guangdong and Zhejiang, China. Using daily reported cumulative case data up until 13 February 2020 from the National Health Commission of China, we report 5- and 10-day ahead forecasts of cumulative case reports. Specifically, …

Trends In Mental Well-Being Of Non-Hispanic White Children Of Midlife Parents With Low Education, Neeraj Bhandari

Public Health Faculty Publications

Background: It is unknown whether recent increase in mortality and morbidity linked to mental despair (eg, suicide, opioid addiction, alcoholism) in midlife non-Hispanic whites (NHWs) was accompanied by declines in mental well-being of NHW children. The author examined aggregate trends in the mental well-being of NHW children between 2003 and 2018. Methods: The author used linear (unadjusted) regression to generate estimates of long period (ie, between 2003-2005 and 2016-2018) and annual change in mental well-being and self-assessed health from the National Health Interview Survey data on 68 057 NHW children (aged 4-17 years). Results: The NHW children showed no significant …

Health Behaviors And Pandemics, Jay E. Maddock, Anna E. Greer

Public Health Faculty Publications

Human health behaviors are essential to reducing the spread and impact of pandemics. However, most behavioral scientists do not work in the area of pandemics given the infrequency of their occurrences. This editorial examines relevant health behavior theories, in particular the precaution adoption process model, and how these apply to the COVID-19 pandemic.

Diet Quality As A Mediator Of The Relation Between Income-To- Poverty Ratio And Overweight/Obesity Among Adults: Moderating Effect Of Sex, Sajeevika S. Daundasekara, Nipa P. Kamdar, Ashley Dao, Anna E. Greer, A. Lisako, J. Mckyer, Daphne C. Hernandez

Public Health Faculty Publications

Poverty status influences obesity and dietary quality, and dietary quality influences obesity. How these relationships differ by sex is unclear. The current study aims were to 1) determine whether dietary quality mediates the relation between income-to-poverty ratio (IPR) and overweight/obesity (OV/OB) among men and women, separately, and 2) determine whether either of the mediated paths differs by sex. Four cycles of NHANES (2007-2014) were merged to obtain an unweighted study sample of 12,768 adults with complete data. Exposure variables included self-reported measures of IPR, Healthy Eating index (HEI) total score to measure diet quality, and sex. Direct assessment of height …

Decline In Telomere Length By Age And Effect Modification By Gender, Allostatic Load And Comorbidities In National Health And Nutrition Examination Survey (1999-2002), Saruna Ghimire, Carl V. Hill, Francisco S. Sy, Rachelle Rodriguez

Public Health Faculty Publications

Background: This study aims to assess the decline in telomere length (TL) with age and evaluate effect modification by gender, chronic stress, and comorbidity in a representative sample of the US population. Methods: Cross-sectional data on 7826 adults with a TL measurement, were included from the National Health and Nutrition Examination Survey, years 1999–2002. The population rate of decline in TL across 10-year age categories was estimated using crude and adjusted regression. Results: In an adjusted model, the population rate of decline in TL with age was consistent and linear for only three age categories: 20–29 (β = -0.0172, 95% …

The Impact Of Pedestrian Crossing Flags On Driver Yielding Behavior In Las Vegas, Nv, Sheila Clark, Courtney Coughenour, Kelly Bumgarner, Hanns De La Fuente-Mella, Chantel Reynolds, James Abelar

Public Health Faculty Publications

Walking is the most affordable, accessible, and environmentally friendly method of transportation. However, the risk of pedestrian injury or death from motor vehicle crashes is significant, particularly in sprawling metropolitan areas. The purpose of this study was to examine the effect of pedestrian crossing flags (PCFs) on driver yielding behaviors. Participants crossed a marked, midblock crosswalk on a multilane road in Las Vegas, Nevada, with and without PCFs, to determine if there were differences in driver yielding behaviors (n = 160 crossings). Trained observers recorded (1) the number of vehicles that passed in the nearest lane without yielding while the …

Health-Information Seeking And Intention To Quit Smoking: Do Health Beliefs Have A Mediating Role?, Soumya Upadhyay, Justin Loard, Maxim Gakh

Public Health Faculty Publications

Background: Smoking is a leading cause of preventable deaths. Smoking cessation can reduce the risk of smoking-associated disease and death. But smoking cessation involves behaviour change. Existing research indicates that health-information seeking and health-promoting behaviours can be positively associated. However, in the context of smoking, the relationship between seeking health information and intending to quit smoking remains only partially understood. Aim: This study aimed to examine the relationship between seeking health information and intending to quit smoking and to determine whether this relationship is mediated by health beliefs. Methods: We used data from the fourth cycle of the US National …

Dissociation Between The Growing Opioid Demands And Drug Policy Directions Among The U.S. Older Adults With Degenerative Joint Diseases, Pearl Kim Phd, Takashi Yamashita Phd, Mph, Ma, Jay J. Shen Phd, Seong-Min Park Phd, Sung-Youn Chun Phd, Sun Jung Kim Phd, Mhsa, Jinwook Hwang Md, Phd, Se Won Lee Md, Georgia Dounis Dds, Ms, Hee-Taik Kang Md, Phd, Yong-Jae Lee Md, Phd, Dong-Hun Han Dds, Phd, Ji Eun Kim Phd, Hyeyoung Yeom Md, David Byun Do, Tsigab Bahta Md, Ji Won Yoo Md

Public Health Faculty Publications

We aim to examine temporal trends of orthopedic operations and opioid-related hospital stays among seniors in the nation and states of Oregon and Washington where marijuana legalization was accepted earlier than any others. As aging society advances in the United States (U.S.), orthopedic operations and opioid-related hospital stays among seniors increase in the nation. A serial cross-sectional cohort study using the healthcare cost and utilization project fast stats from 2006 through 2015 measured annual rate per 100,000 populations of orthopedic operations by age groups (45–64 vs 65 and older) as well as annual rate per 100,000 populations of opioid-related hospital …

A State Of Uncertainty: An Analysis Of Recent State Legislative Proposals To Regulate Preventive Services In The United States, Maxim Gakh, Cody Cris, Prescott Cheong, Courtney Coughenour

Public Health Faculty Publications

This policy brief examines preventive services state legislation trends in the United States during uncertainty regarding the Affordable Care Act (ACA), which requires certain coverage of 4 evidence-based preventive services categories without additional patient costs under §2713. We used a legal mapping approach to search for and analyze state legislation related to preventive services proposed or enacted over a 25-month period of ACA uncertainty. We screened 1231 bills and coded the 76 screened-in bills. Next, we determined their characteristics and examined trends. Bills originated in 28 states, and 69.7% were not enacted. Only 3.9% contained requirements contingent on ACA modifications. …

Two-Stage Optimal Designs With Survival Endpoint When The Follow-Up Time Is Restricted, Guogen Shan, Hua Zhang

Public Health Faculty Publications

Background: Survival endpoint is frequently used in early phase clinical trials as the primary endpoint to assess the activity of a new treatment. Existing two-stage optimal designs with survival endpoint either over estimate the sample size or compute power outside the alternative hypothesis space. Methods: We propose a new single-arm two-stage optimal design with survival endpoint by using the one-sample log rank test based on exact variance estimates. This proposed design with survival endpoint is analogous to Simon’s two-stage design with binary endpoint, having restricted follow-up. Results: We compare the proposed design with the existing two-stage designs, including the two-stage …

A Qualitative Study On Parental And Community Stakeholder Views Of The Link Between Full-Day Kindergarten And Health In Southern Nevada, Courtney Coughenour, Jennifer Pharr, Maxim Gakh Jd, Mph, Sheila Clark, Prescott Cheong

Public Health Faculty Publications

Studies show that children who attend full-day kindergarten (FDK) experience both academic and developmental benefits compared to children who attend half-day programs. Sectors outside of health, such as education, can have important intended and unintended impacts on health. The purpose of this qualitative study was to understand perceptions of parental and other stakeholders in Southern Nevada (USA) about the education–health link, and to understand priorities regarding how FDK access could affect health. Two 90-minute focus groups were conducted with 14 adult stakeholder participants representing parents, current and former teachers, and community members. Transcripts were analyzed using conventional content analysis. Eight …

Analysis Of Self-Reported Walking For Transit In A Sprawling Urban Metropolitan Area In The Western U.S., Courtney Coughenour, Hanns De La Fuente-Mella, Alexander Paz

Public Health Faculty Publications

Walkability is associated with increased levels of physical activity and improved health and sustainability. The sprawling design of many metropolitan areas of the western U.S., such as Las Vegas, influences their walkability. The purpose of this study was to consider sprawl characteristics along with well-known correlates of walkability to determine what factors influence self-reported minutes of active transportation. Residents from four neighborhoods in the Las Vegas Metropolitan Area, targeted for their high and low walkability scores, were surveyed for their perceptions of street-connectivity, residential-density, land-use mix, and retail–floor-area ratio and sprawl characteristics including distance between crosswalks, single-entry-communities, high-speed streets, shade, …