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Articles 1141 - 1170 of 1170

Full-Text Articles in Medicine and Health Sciences

Preventing Perinatal Transmission Of Hiv Costs And Effectiveness Of A Recommended Intervention, Robin D. Gorsky, P G. Farnham, Walter L. Straus, Blake Caldwell, D R. Holtgrave, R. J. Simonds, M F. Rogers, Mary Guinan Jan 1996

Preventing Perinatal Transmission Of Hiv Costs And Effectiveness Of A Recommended Intervention, Robin D. Gorsky, P G. Farnham, Walter L. Straus, Blake Caldwell, D R. Holtgrave, R. J. Simonds, M F. Rogers, Mary Guinan

Public Health Faculty Publications

In the United States, nearly all new human immunodeficiency virus (HIV) infections in children are acquired through perinatal (mother-to-infant) transmission. Each year, approximately 7000 infants are born to HIV-infected women in the United States.1 Without intervention, an estimated 15-30% of these infants would become infected.2 In 1994, results of the AIDS Clinical Trial Group (ACTG) Protocol 076 showed that treatment of infected pregnant women and their infants with zidovudine (ZDV) reduced the rate of perinatal HIV transmission from 25% to 8%.3,4 Following these findings, the Public Health Service (PHS) issued recommendations for ZDV therapy to prevent perinatal …


Pcr For Bioaerosol Monitoring: Sensitivity And Environmental Interference, Aj Alvarez, Mark P. Buttner, Linda Stetzenbach Jan 1995

Pcr For Bioaerosol Monitoring: Sensitivity And Environmental Interference, Aj Alvarez, Mark P. Buttner, Linda Stetzenbach

Environmental & Occupational Health Faculty Publications

The PCR technique has potential for use in detection of low concentrations of airborne microorganisms. In this study, the sensitivity of PCR and its susceptibility to environmental interference were assessed with Escherichia coli DH1 as the target organism. Air samples, containing environmental bioaerosols, were collected with AGI-30 samplers and seeded with E. coli DH1 cells. Parallel studies were performed with cells seeded into the sampler prior to collection of air samples to determine the effects of environmental inhibition and sampling stress on the PCR assay. Baseline studies were also performed without environmental challenge or sampling stress to compare two protocols …


An Overview Of The Effectiveness And Efficiency Of Hiv Prevention Programs, D. R. Holtgrave, Noreen L. Qualls, J. W. Curran, Ronald O. Valdiserri, Mary Guinan, William C. Parra Jan 1995

An Overview Of The Effectiveness And Efficiency Of Hiv Prevention Programs, D. R. Holtgrave, Noreen L. Qualls, J. W. Curran, Ronald O. Valdiserri, Mary Guinan, William C. Parra

Public Health Faculty Publications

Because of the enormity of the HIV-AIDS epidemic and the urgency for preventing transmission, HIV prevention programs are a high priority for careful and timely evaluations. Information on program effectiveness and efficiency is needed for decision-making about future HIV prevention priorities. General characteristics of successful HIV prevention programs, programs empirically evaluated and found to change (or not change) high-risk behaviors or in need of further empirical study, and economic evaluations of certain programs are described and summarized with attention limited to programs that have a behavioral basis. HIV prevention programs have an impact on averting or reducing risk behaviors, particularly …


Menopausal Hormone Replacement: Not Necessarily Routine, Mary Guinan Apr 1994

Menopausal Hormone Replacement: Not Necessarily Routine, Mary Guinan

Public Health Faculty Publications

No abstract provided.


Analysis And Evaluation Of The Workplace Exposure Assessment Workbook Developed By Keith Tait Including Some Recommended Revisions, Lisa Hebberd Oct 1993

Analysis And Evaluation Of The Workplace Exposure Assessment Workbook Developed By Keith Tait Including Some Recommended Revisions, Lisa Hebberd

UNLV Theses, Dissertations, Professional Papers, and Capstones

Some risk due to the contamination of workplace environments is an inevitable part of human lives. These risks can often be reduced by improving the control of environmental pollution in the workplace. An extremely important challenge for any industry is to develop a mechanism to identify acceptable levels of safety, or "acceptable risk" in the workplace for specific situations, and to assure adequate quality control over measured or calculated exposure concentrations and their possible contributions to adverse health effects.


War Crimes Of The 90s: Rape As A Strategy, Mary Guinan Mar 1993

War Crimes Of The 90s: Rape As A Strategy, Mary Guinan

Public Health Faculty Publications

Historically, only men went to war. The winners took the losers' women and could rape, enslave, or kill them. As we moved into a more modern civilization, the rights of the winner over the women of the loser became less clear and were only vaguely documented. Even for modern war historians, what happens to the men on and off the battlefield is the main preoccupation. After all, women do not face combat and what happens to them seems unimportant. The rape of women by conquering armies has continued through all wars, but has rarely been considered a war crime, especially …


Monitoring Of Fungal Spores In An Experimental Indoor Environment To Evaluate Sampling Methods And The Effects Of Human Activity On Air Sampling, Mark P. Buttner, Linda Stetzenbach Jan 1993

Monitoring Of Fungal Spores In An Experimental Indoor Environment To Evaluate Sampling Methods And The Effects Of Human Activity On Air Sampling, Mark P. Buttner, Linda Stetzenbach

Environmental & Occupational Health Faculty Publications

Aerobiological monitoring was conducted in an experimental room to aid in the development of standardized sampling protocols for airborne microorganisms in the indoor environment. The objectives of this research were to evaluate the relative efficiencies of selected sampling methods for the retrieval of airborne fungal spores and to determine the effect of human activity on air sampling. Dry aerosols containing known concentrations of Penicillium chrysogenum spores were generated, and air samples were taken by using Andersen six-stage, Surface Air System, Burkard, and depositional samplers. The Andersen and Burkard samplers retrieved the highest numbers of spores compared with the measurement standard, …


A Dream For The Future Of Public Health, Mary Guinan Jan 1993

A Dream For The Future Of Public Health, Mary Guinan

Public Health Faculty Publications

The following is a commencement address Dr. Guinan delivered at the Emory University School of Public Health in May 1992, just weeks after riots erupted in response to the Rodney King verdict. Her remarks were very timely, but her message is timeless. It is just as relevant today, more than a year later, as it was that day.


Finding Hiv-Infected Women - The Clinician's Role, Mary Guinan Jan 1992

Finding Hiv-Infected Women - The Clinician's Role, Mary Guinan

Public Health Faculty Publications

An estimated 100,000 women are currently infected with the human immunodeficiency virus (HIV) in the United States, and a great majority of them are unaware of their condition. Approximately 20,000 HIV-infected women were identified through publicly funded HIV screening programs in 1989 and 1990, and an unknown number through private screening. Because most HIV-infected women are believed to be in the lower socioeconomic strata, it is unlikely that a significant number were identified in the private sector. Therefore, up to 80% of HIV-positive women may not know they are infected.


Female Condoms, An Urgent Need, Mary Guinan Jul 1991

Female Condoms, An Urgent Need, Mary Guinan

Public Health Faculty Publications

As of February 1991, more than 16,000 cases of AIDS in women had been reported in the United States, but the ". tidal wave of cases in women is yet to come. World Health Organization (WHO) estimates of the number of women infected with the human immunodeficiency virus (HIV) range from 1.5 million in Africa to I 00,000 in the United States. Within the next ten years, the majority of these women will develop AIDS and die. Some will live a bit longer, but all are eventually doomed to die prematurely. Most will not live to see their 40th year.


Evaluation Of Four Aerobiological Sampling Methods For The Retrieval Of Aerosolized Pseudomonas Syringae, Mark P. Buttner, Linda Stetzenbach Apr 1991

Evaluation Of Four Aerobiological Sampling Methods For The Retrieval Of Aerosolized Pseudomonas Syringae, Mark P. Buttner, Linda Stetzenbach

Environmental & Occupational Health Faculty Publications

The Andersen six-stage impactor, the SAS (Surface Air System) impactor, the AGI-30 impinger, and gravity plates were evaluated for the retrieval of aerosol-releasedPseudomonas syringae. The upper limits of the impactor samplers were exceeded at a spray concentration of 10^7 CFU/ml, indicating that these samplers are not appropriate for monitoring high airborne concentrations. Decreased cell concentrations were retrieved with increased sampling time for the Andersen and AGI samplers, indicating that a minimum sampling time is preferable for monitoring aerosolized vegetative cells.


The Right To Die: An Old Woman's Formula, Mary Guinan Mar 1991

The Right To Die: An Old Woman's Formula, Mary Guinan

Public Health Faculty Publications

On December 26, 1990, Nancy Cruzan died, 12 days after her feeding tube was removed. She had been in an irreversible coma for seven years and her parents had sued for the right to remove the feeding tube that was keeping her alive. The pain and suffering of her family in coming to this decision was certainly compounded by those who disagreed with them and tried to prevent the extubation. Whether one agrees with this particular decision or not, most of us will not be faced with such clear alternatives, ie, leave the tube in or take it out in …


Pms And Eosinophilia-Myalgia Syndrome, Mary Guinan Mar 1990

Pms And Eosinophilia-Myalgia Syndrome, Mary Guinan

Public Health Faculty Publications

No abstract provided.


Amwa Endorses Uniform Mammography Screening, Mary Guinan Jan 1990

Amwa Endorses Uniform Mammography Screening, Mary Guinan

Public Health Faculty Publications

Breast cancer is gaining on us at an increasing rate each year. In 1990 in the United States alone we expect about 145,000 new cases and 45,000 breast cancer deaths in women. What are we doing about it? What is AMWA doing, and what are women physicians doing- for themselves and their patients? Can we do anything? The answer is yes, we can. We can reduce mortality considerably if the cancer is detected early. The five-year survival rate for women with breast cancer diagnosed in its early (localized) stages is 90%, but for women with cancer diagnosed after it has …


Domestic Violence: Physicians A Link To Prevention, Mary Guinan Jan 1990

Domestic Violence: Physicians A Link To Prevention, Mary Guinan

Public Health Faculty Publications

Domestic violence may result in more injuries and fatalities for women than automobile crashes, muggings, and rapes combined, but according to a recent editorial, physicians largely ignore the problem. Evidence showed that a majority of women treated at an emergency facility for injuries resulting from violent acts of spouses or other persons known to the victims were discharged without any arrangement being made for their future safety. Physicians rarely inquired about an injury victim's past sexual or physical abuse, living arrangements, or future prospects of safety.


Women And Crack Addiction, Mary Guinan Jul 1989

Women And Crack Addiction, Mary Guinan

Public Health Faculty Publications

A smokable form of cocaine has recently been introduced to the United States. First documented in New York in 1985, the use of rock cocaine or crack has spread rapidly throughout the country since then. Until crack appeared, noninjectable cocaine use was largely a problem in the middle and upper classes because of its high price. Crack has changed that; five and ten dollar packages are readily available. Crack produces a short-lived high and may enhance sexual desire and performance. The rapidity of the spread of crack in inner cities is extraordinary but the movement into rural areas has been …


Three Cheers For Elective Hysterectomy, Mary Guinan May 1989

Three Cheers For Elective Hysterectomy, Mary Guinan

Public Health Faculty Publications

Hysterectomy is the second (after cesarean section) most commonly performed major surgical procedure in the United States today.1 About [650,000 American women will have hysterectomies in 1989. Thirty-seven percent of all US women will have had a hysterectomy by the time they reach age 60. The number of hysterectomies increased dramatically Born 1965 to 1975, but then leveled off and decreased to the present level of about 7 per 1000 women. The ~ghest rates occur in women aged 35 to 44 years, the age group the so called baby boomers are now entering in large numbers. Therefore, if the age-specific …


What Is The Health Impact Of Day Care Attendance On Infants And Preschoolers?, Ruth L. Berkelman, Mary Guinan, Phen B. Thacker Jan 1989

What Is The Health Impact Of Day Care Attendance On Infants And Preschoolers?, Ruth L. Berkelman, Mary Guinan, Phen B. Thacker

Public Health Faculty Publications

The impact of various child care arrangements on the health of infants and preschool children is not known in any systematic way, yet by 1990 more than 10 million of these children may be receiving their care in day care facilities (1). Concerns over the health of these children and health practices within day care facilities have already led some States to place regulation of day care facilities under the jurisdiction of the department of health (2,3), and others are presently considering such legislation. In addition, the American Academy of Pediatrics has recently published "Health in Day Care," a manual …


Herpes Simplex Virus Type 2 Antibodies: High Prevalence In Monogamous Women In Costa Rica, Mark W. Oberle, Luis Rosero-Bixby, Francis K. Lee, Maria Sanchez-Braverman, A J. Nahmias, Mary Guinan Jan 1989

Herpes Simplex Virus Type 2 Antibodies: High Prevalence In Monogamous Women In Costa Rica, Mark W. Oberle, Luis Rosero-Bixby, Francis K. Lee, Maria Sanchez-Braverman, A J. Nahmias, Mary Guinan

Public Health Faculty Publications

We studied the prevalence of antibody to Herpes simplex virus types I and 2 (HSV-I and HSV-2) in 766 randomly selected Costa Rican women 25-59 years of age in a national household survey in 1984-1985. Overall, 97.1% were seropositive for HSV-l and 39.4% for HSV -2. Only 1.1% of HSV -2 seropositive women gave a history of symptomatic genital herpes. HSV-2 virus antibody increased with age and with the number of lifetime sexual partners. HSV -2 seroprevalence among women who reported only 1 lifetime sexual partner was almost twice as high as the prevalence among women who denied sexual experience …


Cigarette Advertising To Women: Taking Responsibility, Mary Guinan Jul 1988

Cigarette Advertising To Women: Taking Responsibility, Mary Guinan

Public Health Faculty Publications

A variety of magazines are directed at American women. Some emphasize fashion, while others cover child rearing, homemaking, or gardening; still others stress career, coping with multiple women's roles, or feminism. Almost without exception, women's health concerns are periodically addressed by these magazines. Because women are the target audience, I have always assumed that these publications have women's best interests at heart. Is this a realistic assumption? I'm not sure. I also do not know what influence women's magazines have on women's health behavior, but I think it is substantial. If this is so, then shouldn't we hold these publications …


Virginity And Celibacy As Health Issues, Mary Guinan Mar 1988

Virginity And Celibacy As Health Issues, Mary Guinan

Public Health Faculty Publications

Sexual behavior is both a health issue and a moral issue. Hence public education on sexuality has traditionally come from two main sources, those individuals or groups concerned with health and those concerned with morals. In his book No Magic Bullet (Oxford University Press, 1985), Allan Brandt describes the tensions that developed between these groups over the control of sexually transmitted diseases in the United States early in this century. Both groups wanted to control sexual behavior, but for different reasons. Public health personnel wanted to change sexual behavior in order to control infection and disease, while moralists believed that …


Pms Or Perifollicular Phase Euphoria?, Mary Guinan Jan 1988

Pms Or Perifollicular Phase Euphoria?, Mary Guinan

Public Health Faculty Publications

Why is it that so little is known about PMS? First of all, there is no agreement on what PMS is. If investigators are referring to different sets of symptoms, how can studies be comparable? In fact, they are not. Not only are the symptoms different, but the timing of symptoms is different, Some studies describe symptoms that occur 7 to 10 days before the onset of menses, while others include symptoms that begin 14 days before the onset of menses and continue for 7 days after onset. This definition suggests that women may have PMS-related symptoms during 21 days …


Have You Had Your Mammogram, Doctor?, Mary Guinan Jan 1988

Have You Had Your Mammogram, Doctor?, Mary Guinan

Public Health Faculty Publications

Breast cancer incidence continues to increase in the United States, with more than 130,000 new cases and 42,000 deaths expected this year. Today, one in every ten women in the United States will develop breast cancer at sometime during their lives. Breast cancer can be prevented by early prophylactic bilateral mastectomy, ie, removal of the breasts before any signs or symptoms develop. This practice was advocated by a male gynecologist colleague of mine. When I expressed horror at his suggestion that I have such a procedure at age 32, he challenged me to defend myself against advocating a practice that …


Women And Aids: The Future Is Grim, Mary E. Guinan, Ann Hardy Sep 1987

Women And Aids: The Future Is Grim, Mary E. Guinan, Ann Hardy

Public Health Faculty Publications

Recently, we analyzed the reported cases of acquired immunodeficiency syndrome (AIDS) in women in the United States.1 We found two areas of great concern: first, women are more likely than men to acquire AIDS through heterosexual intercourse, and second, women are the source of disease for about 80% of children with AIDS. In this column we will discuss the source and distribution of AIDS in women, and in a future piece we will discuss women as the source of infection for pediatric AIDS cases.


Osteoporosis And Ert--The Jury Is Still Out, Mary E. Guinan, Karen Steinberg, Lambertina Freni-Titulaer May 1987

Osteoporosis And Ert--The Jury Is Still Out, Mary E. Guinan, Karen Steinberg, Lambertina Freni-Titulaer

Public Health Faculty Publications

Bone loss in women accelerates immediately after menopause, often leading to osteoporosis and an increased risk of bone fractures. In 1985,247,000 hip fractures occurred in people over 45 years of age. Among those who live to be 90, one-third of women and one-sixth of men will experience hip fractures. Six months after fracture, 25% of victims will not be able to carry out their usual activities, and 50% will need assistance to do so. Hip fractures are not only a serious cause of morbidity but they also increase the risk of mortality in older people. Because the proportion of the …


Women, Children And Aids, Mary Guinan Jan 1987

Women, Children And Aids, Mary Guinan

Public Health Faculty Publications

More than 500 cases of acquired immune deficiency syndrome (AlDS) in children (ages I3 and under) had been reported to the Centers for Disease Control as of August , 1987. Of these children, 78% were infected perinatally by their mothers. The ratio of AIDS cases among women to AIDS cases among ; i children has remained stable at approximately 5:1 for several years. So, for the foreseeable future, we can expect that for every five reports of women with AIDS, one child with AIDS will be reported. As is the CMe with other sexually transmitted diseases, AIDS causes a disproportionately …


Letter To The Editor (Human Immunodeficiency Virus In Costa Rica), Mark W. Oberle, Charles A. Schable, Mary Guinan, Luis Rosero Dec 1986

Letter To The Editor (Human Immunodeficiency Virus In Costa Rica), Mark W. Oberle, Charles A. Schable, Mary Guinan, Luis Rosero

Public Health Faculty Publications

Recent reports of 12 confirmed cases of acquired immunodeficiency syndrome (AIDS) in Costa Rica have generated interest in the extent of spread of human T-lymphotropic virus type III/LAV (HTLV-III) in Latin America (1). To date, all cases of AIDS in Costa Rica have occurred in members of previously identified, high-risk groups, chiefly hemophiliacs. To examine the possibility of heterosexual transmission in Costa Rica, we utilized sera collected in a population-based case-control study of cervical cancer, conducted by the Costa Rican Demographic Association and other institution.


Heterosexual And Homosexual Patients With The Acquired Immunodeficiency Syndrome: A Comparison Of Surveillance, Interview, And Laboratory Data, Mary Guinan, Pauline A. Thomas, Paul F. Pinksy, James T. Goodrich, Richard M. Selik, H W. Jaffe, H W. Haverkos, Gary Noble, J W. Curran Jan 1984

Heterosexual And Homosexual Patients With The Acquired Immunodeficiency Syndrome: A Comparison Of Surveillance, Interview, And Laboratory Data, Mary Guinan, Pauline A. Thomas, Paul F. Pinksy, James T. Goodrich, Richard M. Selik, H W. Jaffe, H W. Haverkos, Gary Noble, J W. Curran

Public Health Faculty Publications

Homosexual and heterosexual patients with the acquired immunodeficiency syndrome were compared by risk group. Race; diagnoses; history of sexually transmitted diseases, sexual behavior, and drug use; and socioeconomic indicators differed considerably among the risk groups, suggesting different risk factors for acquisition of the syndrome. Patients in the homosexual, intravenous drug user, and Haitian risk groups differed in their serologic response to cytomegalovirus and syphilis testing, presumably due to lifestyle-related exposures. Differences in the rate of recovery of cytomegalovirus, serum levels of IgA and IgG, and antibody titers to Epstein-Barr virus were noted among patients with different diagnoses. We conclude that …


National Case-Control Study Of Kaposi's Sarcoma And Pneumocystis Carinii Pneumonia In Homosexual Men: Part 1. Epidemiologic Results, Harold W. Jaffe, Keewhan Choi, Pauline A. Thomas, Harry W. Haverkos, David M. Auerbach, Mary E. Guinan, Martha F. Rogers, Thomas J. Spira, William W. Darrow, Mark A. Kramer, Stephen M. Friedman, James M. Monroe, Alvin E. Friedman-Kien, Linda J. Laubenstein, Michael Marmor, Bijan Safai, Selma K. Dritz, Salvatore J. Crispi, Shirley L. Fannin, John P. Orkwis, Alexander Kelter, Wilmon R. Rushing, Stephen B. Thacker, James W. Curran Jan 1983

National Case-Control Study Of Kaposi's Sarcoma And Pneumocystis Carinii Pneumonia In Homosexual Men: Part 1. Epidemiologic Results, Harold W. Jaffe, Keewhan Choi, Pauline A. Thomas, Harry W. Haverkos, David M. Auerbach, Mary E. Guinan, Martha F. Rogers, Thomas J. Spira, William W. Darrow, Mark A. Kramer, Stephen M. Friedman, James M. Monroe, Alvin E. Friedman-Kien, Linda J. Laubenstein, Michael Marmor, Bijan Safai, Selma K. Dritz, Salvatore J. Crispi, Shirley L. Fannin, John P. Orkwis, Alexander Kelter, Wilmon R. Rushing, Stephen B. Thacker, James W. Curran

Public Health Faculty Publications

To identify risk factors for the occurrence of Kaposi's sarcoma and Pneumocystis carinii pneumonia in homosexual men, we conducted a case-control study in New York City, San Francisco, Los Angeles, and Atlanta. Fifty patients (cases) (39 with Kaposi's sarcoma, 8 with pneumocystis pneumonia, and 3 with both) and 120 matched homosexual male controls (from sexually transmitted disease clinics and private medical practices) participated in the study. The variable most strongly associated with illness was a larger number of male sex partners per year (median, 61 for patients; 27 and 25 for clinic and private practice controls, respectively). Compared with controls, …


Vaginal Colonization With Staphylococcus Aureus In Healthy Women: A Review Of Four Studies, Mary Guinan, Bruce B. Dan, Richard J. Guidotti, Arthur L. Reingold, George P. Schmid, Elena J. Bettoli, Joseph G. Lossick, Kathryn N. Shands, Mark A. Kramer, Nancy T. Hargrett, Roger L. Anderson, Claire V. Broome Jan 1982

Vaginal Colonization With Staphylococcus Aureus In Healthy Women: A Review Of Four Studies, Mary Guinan, Bruce B. Dan, Richard J. Guidotti, Arthur L. Reingold, George P. Schmid, Elena J. Bettoli, Joseph G. Lossick, Kathryn N. Shands, Mark A. Kramer, Nancy T. Hargrett, Roger L. Anderson, Claire V. Broome

Public Health Faculty Publications

Four studies assessed the frequency of vaginal Staphylococcus aureus colonization in healthy women and associated risk factors. An association was found between S. aureus vaginal colonization and colonization at the labia minora and the anterior nares. Significant risk factors associated with an increased risk of vaginal S. aureus in at least one study were a history of genital herpes simplex infection, insertion of tampons without an applicator, and the use of Rely (Procter & Gamble) tampons. The use of systemic antibiotics within 2 weeks of the vaginal culture decreased the risk of recovery of S. aureus. The overall frequency …