Medicine and Health Sciences Commons^™

Acute Alcohol Consumption Impairs Controlled But Not Automatic Processes In A Psychophysical Pointing Paradigm., Kevin Johnston, Brian Timney, Melvyn A Goodale

Brain and Mind Institute Researchers' Publications

Numerous studies have investigated the effects of alcohol consumption on controlled and automatic cognitive processes. Such studies have shown that alcohol impairs performance on tasks requiring conscious, intentional control, while leaving automatic performance relatively intact. Here, we sought to extend these findings to aspects of visuomotor control by investigating the effects of alcohol in a visuomotor pointing paradigm that allowed us to separate the influence of controlled and automatic processes. Six male participants were assigned to an experimental "correction" condition in which they were instructed to point at a visual target as quickly and accurately as possible. On a small …

Habituation Of Reflexive And Motivated Behavior In Mice With Deficient Bk Channel Function., Marei Typlt, Magdalena Mirkowski, Erin Azzopardi, Peter Ruth, Peter K D Pilz, Susanne Schmid

Brain and Mind Institute Researchers' Publications

Habituation is considered the most basic form of learning. It describes the decrease of a behavioral response to a repeated non-threatening sensory stimulus and therefore provides an important sensory filtering mechanism. While some neuronal pathways mediating habituation are well described, underlying cellular/molecular mechanisms are not yet fully understood. In general, there is an agreement that short-term and long-term habituation are based on different mechanisms. Historically, a distinction has also been made between habituation of motivated versus reflexive behavior. In recent studies in invertebrates the large conductance voltage- and calcium-activated potassium (BK) channel has been implicated to be a key player …

Mice With Deficient Bk Channel Function Show Impaired Prepulse Inhibition And Spatial Learning, But Normal Working And Spatial Reference Memory., Marei Typlt, Magdalena Mirkowski, Erin Azzopardi, Lukas Ruettiger, Peter Ruth, Susanne Schmid

Brain and Mind Institute Researchers' Publications

Genetic variations in the large-conductance, voltage- and calcium activated potassium channels (BK channels) have been recently implicated in mental retardation, autism and schizophrenia which all come along with severe cognitive impairments. In the present study we investigate the effects of functional BK channel deletion on cognition using a genetic mouse model with a knock-out of the gene for the pore forming α-subunit of the channel. We tested the F1 generation of a hybrid SV129/C57BL6 mouse line in which the slo1 gene was deleted in both parent strains. We first evaluated hearing and motor function to establish the suitability of this …

Synaptic Scaffold Evolution Generated Components Of Vertebrate Cognitive Complexity, Jess Nithianantharajah, Noboru H. Komiyama, Andrew Mckechanie, Mandy Johnstone, Douglas H. Blackwood, David St.Clair, Richard D. Emes, Louie N. Van De Lagemaat, Lisa M. Saksida, Timothy J. Bussey, Seth G. Grant

Brain and Mind Institute Researchers' Publications

The origins and evolution of higher cognitive functions, including complex forms of learning, attention and executive functions, are unknown. A potential mechanism driving the evolution of vertebrate cognition early in the vertebrate lineage (550 million years ago) was genome duplication and subsequent diversification of postsynaptic genes. Here we report, to our knowledge, the first genetic analysis of a vertebrate gene family in cognitive functions measured using computerized touchscreens. Comparison of mice carrying mutations in each of the four Dlg paralogs showed that simple associative learning required Dlg4, whereas Dlg2 and Dlg3 diversified to have opposing functions in complex cognitive …

Errors In Device Localization In Mri Using Z-Frames., Jeremy Cepek, Blaine A Chronik, Aaron Fenster

Brain and Mind Institute Researchers' Publications

The use of a passive MRI-visible tracking frame is a common method of localizing devices in MRI space for MRI-guided procedures. One of the most common tracking frame designs found in the literature is the z-frame, as it allows six degree-of-freedom pose estimation using only a single image slice. Despite the popularity of this design, it is susceptible to errors in pose estimation due to various image distortion mechanisms in MRI. In this paper, the absolute error in using a z-frame to localize a tool in MRI is quantified over various positions of the z-frame relative to the MRI isocenter, …

Language, Reading, And Math Learning Profiles In An Epidemiological Sample Of School Age Children., Lisa M D Archibald, Janis Oram Cardy, Marc F Joanisse, Daniel Ansari

Brain and Mind Institute Researchers' Publications

Dyscalculia, dyslexia, and specific language impairment (SLI) are relatively specific developmental learning disabilities in math, reading, and oral language, respectively, that occur in the context of average intellectual capacity and adequate environmental opportunities. Past research has been dominated by studies focused on single impairments despite the widespread recognition that overlapping and comorbid deficits are common. The present study took an epidemiological approach to study the learning profiles of a large school age sample in language, reading, and math. Both general learning profiles reflecting good or poor performance across measures and specific learning profiles involving either weak language, weak reading, weak …

Differential Effects Of Parkinson's Disease And Dopamine Replacement On Memory Encoding And Retrieval., Alex A Macdonald, Ken N Seergobin, Adrian M Owen, Ruzbeh Tamjeedi, Oury Monchi, Hooman Ganjavi, Penny A Macdonald

Brain and Mind Institute Researchers' Publications

Increasingly memory deficits are recognized in Parkinson's disease (PD). In PD, the dopamine-producing cells of the substantia nigra (SN) are significantly degenerated whereas those in the ventral tegmental area (VTA) are relatively spared. Dopamine-replacement medication improves cognitive processes that implicate the SN-innervated dorsal striatum but is thought to impair those that depend upon the VTA-supplied ventral striatum, limbic and prefrontal cortices. Our aim was to examine memory encoding and retrieval in PD and how they are affected by dopamine replacement. Twenty-nine PD patients performed the Rey Auditory Verbal Learning Test (RAVLT) and a non-verbal analogue, the Aggie Figures Learning Test …

Everyday Confrontation Of Discrimination: The Well-Being Costs And Benefits To Women Over Time., Mindi D. Foster

Psychology Faculty Publications

Taking action against discrimination has positive consequences for well-being (e.g., Cocking & Drury, 2004) but most of this research has focused on collective actions and has used methodologies assessing one point in time. This study therefore used a diary methodology to examine how women’s everyday confrontations of discrimination would affect measures of subjective and psychological well-being, and how these relationships would change over time. In a 28-day online diary study, women indicated their daily experience of discrimination, described their response, and completed measures of well-being. Results showed that at the beginning of the study, using indirect confrontation predicted greater well-being …

How Do Interviewers And Children Discuss Individual Occurrences Of Alleged Repeated Abuse In Forensic Interviews?, Sonja P. Brubacher, Lindsay C. Malloy, Michael E. Lamb, Kim Roberts

Psychology Faculty Publications

Police interviews (n = 97) with 5- to 13-year-olds alleging multiple incidents of sexual abuse were examined to determine how interviewers elicited and children recounted specific instances of abuse. Coders assessed the labels for individual occurrences that arose in interviews, recording who generated them, how they were used, and other devices to aid particularisation such as the use of episodic and generic language. Interviewers used significantly more temporal labels than did children. With age, children were more likely to generate labels themselves, but most children generated at least one label. In 66% of the cases, interviewers ignored or replaced …

Neuropsychological Outcome In Relation To Duration Of Early Orphanage Experience, Jacquelyn Marie Perry Avery

Wayne State University Dissertations

In this sample of 144 children with a history of prior orphanage experience, increasing duration of institutionalization is related to decreasing performance for a number of cognitive domains, most consistently verbal measures and executive Functioning measures. The relationships with duration for measures requiring visual-spatial skills were more mixed and a visual reasoning task was found to significantly relate to duration but not a measure of visual memory or a measure of nonverbal achievement. There was little evidence to support a relationship between the duration of institutionalization and fine-motor dexterity. The strongest relationships with duration were observed for language measures followed …

Subordinate-Supervisor Demographic And Perceived Value Similarity: Relationships To Subordinate Perceptions Of Organizational Justice, Charles Levi Wells, Iv

Wayne State University Dissertations

The purpose of this study was to examine the empirical relationship between subordinate-supervisor demographic and value similarity with subordinate perceptions of organizational justice using three structural equation models. The first model indicated that subordinate-supervisor demographic and value similarity were directly related to subordinate perceptions of organizational justice (Direct Model). The second model indicated that subordinate perceived value similarity with their supervisor mediated the relationship between the subordinate-supervisor demographic similarity and subordinate perceptions of organizational justice (Mediated Model). The last model indicated subordinate perceived value similarity with their supervisor moderated the relationship between subordinate-supervisor demographic similarity and subordinate perceptions of organizational …

White Matter Integrity And Age Related Differences In Reaction Time Components, Yiqin Yang

Wayne State University Dissertations

Reduced speed in information processing is a well-documented phenomenon associated with advanced aging. Age-related deterioration in white matter integrity might play a role in age-related increase in reaction time (RT). However, the association between microstructural differences in particular white matter regions or tracts with RT is unclear. Decomposing RT into parts might be a better way to understand the relationship due to multiple processes involved in RT. In a lifespan sample of 90 healthy normotensive participants, this study examined the association between RT components derived from the Ratcliff diffusion model with age related difference in DTI indices of a wide …

Dispositional Mediators Of Burnout Syndrome In A Sample Of Direct Care Staff Employed At Group Homes In A Midwestern State, Cristovao Bartolo Carreira

Wayne State University Dissertations

The current research examined the dispositional characteristics that mediated burnout syndrome in a sample of direct care workers who were employed in group homes for the mentally ill in a Midwestern state. Specifically, the indirect effects that the direct care staff's attachment systems and problem solving ability were examined as they applied to their potential burnout status. Attachment theory, a contemporary psychodynamic theory of personality, was used to provide a context for the study. The researcher studied the interactions between construct subcomponents to address a criticism in the literature stating that only total scores were used to study burnout and …

Psychologists And Medications In The Era Of Interprofessional Care: Collaboration Is Less Problematic And Costly Than Prescribing, William N. Robiner, Tim R. Tumlin, Tanya Tompkins

Faculty Publications

Increasing emphasis on interprofessionalism and teamwork in healthcare renders psychologists’ collaborations critical and invites reexamination of psychologists’ roles related to medications. The Collaboration Level outlined by the APA’s Ad Hoc Task Force is more achievable and in synch with health reform than prescription privileges (RxP). RxP remains controversial due to training and safety concerns, lacking support from health professionals, psychologists, and consumers. Differences in educational preparation of psychologists relative to prescribing professionals are discussed. Enactment of only three of 170 RxP initiatives reveals RxP to be a costly, ineffectual agenda. Alternatives (e.g., integrated care, collaboration, telehealth) increase access without risks …

Vascular Depression: An Early Indicator Of Decline, Daniel Lee Paulson

Wayne State University Dissertations

Women over the age of 80 represent a rapidly growing demographic group. While older women live longer than men, they do so with more years of disability and frailty. The emergence of geriatric disorders such as vascular disease, depression, frailty and cognitive decline in the aging US population place additional strain and expense on the already over-burdened public health care system. Meanwhile, integrated models of care are associated with preserved functional independence, reduced medical costs, and greater satisfaction for both health care providers and patients. Implementation of integrated care demands process-models of disease that contextualize symptoms within broader patterns of …

The Influence Of Gender And Aging On The Neural Circuitry Supporing Facial Emotion Processing In Adults With Major Depressive Disorder, Emily Briceno

Wayne State University Dissertations

Major Depressive Disorder (MDD) is associated with decrements in facial emotion processing (FEP). Previous studies investigating the neural substrates of these decrements have often reported hyperactivity of emotion processing circuitry. Neural circuitry supporting FEP has been shown to be different between healthy men and women, and between young and elder adults. However, no prior studies have investigated how gender and aging affect emotion processing circuitry in individuals with MDD. The present study aimed to investigate the influence of gender and aging on emotion processing circuitry in MDD. One hundred-ten adults, grouped into subgroups according to MDD status, gender, and age …

Weight Loss Surgery Maintenance And Psychosocial Development: A Narrative Perspective, Carrie J. L. Hickman

Walden Dissertations and Doctoral Studies

Bariatric surgery is not the panacea it was once thought to be for weight loss. Due to patient noncompliance issues, many weight loss surgery patients are relapsing and regaining the significant amounts of weight that bariatric surgery had initially helped them to lose. This failure is costly monetarily, psychologically, and medically to both the patient and to society. Using the narratives of 32 post-weight loss surgery patients, this narrative study explored: (a) whether Erikson's psychosocial stages of development occur after weight loss surgery, (b) whether successful patients (defined as those who are able to maintain their weight loss long term) …

The Effect Of Visual Wulst Lesions And Trigeminal Nerve Sectioning On The Discrimination Of Magnetic Inclination In The Homing Pigeon (Columba Livia), Merissa Acerbi

Honors Projects

The ability of homing pigeons to return to their loft from unknown places has fascinated scientists for centuries. It is well established that homing pigeons, like migratory birds, posses an innate magnetic inclination compass to determine direction by measuring the angle between the magnetic field vector and the Earth's surface. Recent work has indicated that the avian magnetic compass is light mediated and appears to mediate magnetic information to the brain. This occurs via a visual pathway with processing in the visual Wulst area of the forebrain. There is, however, also evidence from other avian species that magnetic direction may …

Exploring Biopsychosocial (Bps) Facets Of Chronic Obstructive Pulmonary Disease (Copd) In Patients In An Acute Inpatient Physical Rehabilitation Facility (Irf), Ronnetta Williams

Theses and Dissertations--Educational, School, and Counseling Psychology

From a BPS perspective, COPD and other chronic diseases may have a significant negative impact on those living with them and may be associated with higher rates of depression and anxiety and lower levels of health-related quality of life (HRQOL). Certain factors, such as spirituality, may influence the negative impact of chronic disease on the relationship between mood and functional independence and HRQOL. Also, gender may influence the relationship between mood, spirituality, and HRQOL for men and women living with chronic diseases. The current study included 136 patients undergoing physical rehabilitation at an IRF. Anxiety, depression, spirituality, HRQOL, and functional …

Memory, Cognition, And The Effect Of A Music Intervention On Healthy Older Adults, Shannon L. Bowles

Theses and Dissertations--Gerontology

Music is a powerful modality that can bring about changes in individuals of all ages. This research employed both an experimental and quasi-experimental design to identify the effects of music as it influenced psychological well-being, memory, and cognition among older adults. Specifically, it addressed three aims: (a) To determine to what extent learning to play a music instrument later in life influenced psychological well-being and cognitive function of non-institutionalized healthy seniors, (b) To determine the effects of the amount of music involvement on psychological well-being and cognitive function (c) To determine the benefit of music for those with limited/no music …

Role Of Health Behaviors In Sexual Quality Of Life Among Hematopoietic Stem Cell Transplant Survivors, Keagan Lee Mcpherson

All Graduate Theses, Dissertations, and Other Capstone Projects

Hematopoietic stem cell transplant (HSCT) recipients are a population increasingly characterized by survivorship. A psychosocial outcome integral to overall quality of life and optimal survivorship outcomes is sexual quality of life (SQOL). In this arena, HSCT patients' prognostics are markedly grim. Though examinations of variables that affect overall survivorship in HSCT patients are relatively novel, SQOL outcomes have still received a disproportionately minimal amount of focus both in research and practice. Because health behaviors and their correlates are implicated in SQOL outcomes in the general population as well as survivorship and overall QOL outcomes in HSCT patients, inquiring about the …

An Analysis Of Treatment Retention And Attrition In An Australian Therapeutic Community For Substance Abuse Treatment, Mark Robert Porter

Theses: Doctorates and Masters

Research undertaken in the last three decades has consistently reported that the length of time spent in inpatient and outpatient alcohol and other drug (AOD) treatment programs predicts treatment success (De Leon, Melnick, Kressel, & Jainchill, 1994; Hubbard, Craddock, & Anderson, 2003; Simpson, Joe, Fletcher, Hubbard, & Anglin, 1999). However, treatment attrition rates are high and present a major problem for improving treatment outcomes. Various factors that have been reportedly associated with increased AOD treatment attrition rates include being female, younger clients, clients using methamphetamines, and clients with elevated psychopathology scores. The aim of this thesis is to improve understanding …

Impulsivity Like Traits And Risky Driving Behaviors Among College Students, Matthew R. Pearson, Elaine M. Murphy, Ashley N. Doane

Psychology Faculty Publications

The present study examined the predictive effects of five impulsivity-like traits (Premeditation, Perseverance, Sensation Seeking, Negative Urgency, and Positive Urgency) on driving outcomes (driving errors, driving lapses, driving violations, cell phone driving, traffic citations, and traffic collisions). With a convenience sample of 266 college student drivers, we found that each of the impulsivity-like traits was related to multiple risky driving outcomes. Positive Urgency (tendency to act impulsively when experiencing negative affect) was the most robust predictor of risky driving outcomes. Positive Urgency is a relatively newly conceptualized impulsivity-like trait that was not examined in the driving literature previously, suggesting a …

Personality And Substance Abuse, Juliana Gonzalez

Masters Theses

The Big Five have shown to be distinct personality traits that do not overlap and have universal applicability, so this study examined whether there are specific personality trait differences in users of Marijuana, Pain Medication, Sedative/Hypnotics, and Stimulants.

Study was placed in the 50 most visited Craigslist pages in the United States. Anonymous web users (N = 547) were recruited through Craigslist. High Neuroticism was associated with Marijuana and Stimulant use. Low Conscientiousness was associated with Marijuana and Stimulant use. High Extraversion was associated with Pain Medication use only. Implications, limitations, and suggestions for future research were discussed.

Understanding Children's Art Making Preferences: Implications For Art Therapy, Amy Morrison

Expressive Therapies Dissertations

This study employed a phenomenological, qualitative approach to investigate children’s art making preferences. The researcher was curious about the meaning that creating two-dimensional and three-dimensional art forms held for children. Influences and contributions to children’s art making preferences were explored. Lastly the study questioned what children’s artistic preferences mean for the field of art therapy. Theories of art therapy, artistic development, and child development informed the study. Thirteen children ages 5 to 11, four boys and nine girls participated. The researcher requested the children choose a subject and create the subject in both two and three dimensions. A range of …

Get Rich U Or Get Transformed U: Reflections On Catholic Liberal Arts Education In The 21st Century, Thomas G. Plante

Psychology

Catholic liberal arts educators can proclaim boldly that we are in the business of formation and transformation of students at multiple levels and in multiple ways. We want our students to be competent, ethical, and compassionate global citizens who are thoughtful, savvy, deep thinkers who love learning and who love helping others. Research and best practices support the claim that the virtues cultivated by the liberal arts contribute to the flourishing of individuals and society as a whole. Catholic colleges and universities have a long history of promoting the liberal arts, and data from various sources suggest that we are …

Vascular Depression: An Early Warning Sign Of Frailty, Daniel Paulson, Peter A. Lichtenberg

Psychology Faculty Research Publications

Objectives: Frailty is a common geriatric disorder associated with ADL impairment, hospitalization, and death. Phenomenological evidence suggests that late-life depression (Katz, 2004), particularly vascular depression, may be a risk factor for frailty. This study tests that hypothesis.

Methods: We identified a sample of stroke-free women over the age of 80 from the Health and Retirement Survey. The sample included 984 respondents in 2000 (incidence sample). Of these, 459 were non-frail at baseline and still alive in 2004 (prevalence sample). Frail respondents experienced at least three of the following: wasting, exhaustion, weakness, slowness, and falls. Vascular depression was represented using two …

Perception And Attitude About Breast And Cervical Cancer Screening Among Muslim Women In A Midwest University Campus, Tahira Yeasmeen

Open Access Theses

Early detection of breast and cervical cancer through mammograms and Pap smears can improve survival rates. Muslim women in the United States are faced with traditional beliefs and diverse socioeconomic and cultural backgrounds that may affect their knowledge and perceptions about these cancer screening practices. The objective of this study is to determine the overall health status and participation rates, knowledge, and perceptions about, and barriers to, breast and cervical cancer screening among a controlled population of Muslim women. Data were collected from Muslim women residing at or near Purdue University and the Greater Lafayette area via an online questionnaire …

Evaluation Of Using An Interrupted Behavior Chain Procedure To Teach Mands To Children With Autism, Blair Nichole Jacobsen

USF Tampa Graduate Theses and Dissertations

Abstract

Interrupted behavior chain procedures have been shown to be an effective way to teach individuals with intellectual disabilities and autism to mand for missing objects and information concerning missing objects. Research has shown that an interrupted behavior chain procedure is more effective than traditional mand teach trials, which occur at the onset of a behavior chain or in a massed trial format. However, there is a lack of research evaluating the use of interrupted behavior chain procedures to teach vocal mands for missing items and the possible generalization effects thereof. This study evaluated the acquisition of vocal mands for …

The Use Of Video Modeling Plus Video Feedback To Improve Boxing Skills, Charlsey Elizabeth Reynolds

USF Tampa Graduate Theses and Dissertations

Video modeling and video feedback are behavioral procedures that have been shown to increase skill acquisition over time in a variety of environments. This study investigated the use of a video modeling and video feedback procedure, via a multiple baseline design to enhance skill acquisition in boxing. This study also incorporated multiple dimensions of analysis by including data based not only on a percentage of performance with a task analysis, but also the duration of each particular target behavior. The target behaviors for the study included three different boxing combinations, which were operationally defined based on component steps via …