Medicine and Health Sciences Commons^™

Alternations Of Nmda And Gabab Receptor Function In Development: A Potential Animal Model Of Schizophrenia, Monica Bolton

UNLV Theses, Dissertations, Professional Papers, and Capstones

Schizophrenia is a debilitating mental disorder that affects up to 3% of the world population. The behavioral symptoms are categorized into positive and negative symptoms, which appear during late adolescence/early adulthood. Unfortunately, the underlying cellular and molecular mechanisms of the disease are poorly understood. Several hypotheses exist to explain mechanisms contributing to these behavioral alterations. One model proposes that a reduced function of the NMDA glutamate receptor on specific GABAergic interneurons may be responsible for deficits in schizophrenia. Post-mortem investigations provide evidence of reductions in both glutamate and GABA-related proteins in patients with schizophrenia. Further, GABAergic interneurons that are activated …

How To Get Rid Of Thunder Thighs, Helena E. Yang

SURGE

I appreciate the insightful and important things your muffin top has to say to me, but my thunder thighs still think they’re fat.

I’m overweight (sometimes).

On a BMI scale, I fluctuate in and out of the dreaded “overweight” category. While I acknowledge that the BMI scale has its flaws, it was designed to be a quick approximation of weight to height; it is not designed to be a scientific test. Sometimes I tell myself I am super muscular and the scale doesn’t apply to me, but it’s actually not true. [excerpt]

Skill Learning Strengthens Cortical Representations Of Motor Sequences., Tobias Wiestler, Jörn Diedrichsen

Brain and Mind Institute Researchers' Publications

Motor-skill learning can be accompanied by both increases and decreases in brain activity. Increases may indicate neural recruitment, while decreases may imply that a region became unimportant or developed a more efficient representation of the skill. These overlapping mechanisms make interpreting learning-related changes of spatially averaged activity difficult. Here we show that motor-skill acquisition is associated with the emergence of highly distinguishable activity patterns for trained movement sequences, in the absence of average activity increases. During functional magnetic resonance imaging, participants produced either four trained or four untrained finger sequences. Using multivariate pattern analysis, both untrained and trained sequences could …

Erps Reveal The Temporal Dynamics Of Auditory Word Recognition In Specific Language Impairment., Jeffrey G Malins, Amy S Desroches, Erin K Robertson, Randy Lynn Newman, Lisa M D Archibald, Marc F Joanisse

Brain and Mind Institute Researchers' Publications

We used event-related potentials (ERPs) to compare auditory word recognition in children with specific language impairment (SLI group; N=14) to a group of typically developing children (TD group; N=14). Subjects were presented with pictures of items and heard auditory words that either matched or mismatched the pictures. Mismatches overlapped expected words in word-onset (cohort mismatches; see: DOLL, hear: dog), rhyme (CONE -bone), or were unrelated (SHELL -mug). In match trials, the SLI group showed a different pattern of N100 responses to auditory stimuli compared to the TD group, indicative of early auditory processing differences in SLI. However, the phonological mapping …

Treatment Of Psychiatric Inpatients With Relationship Dysfunction Using A Short Term Cognitive Interpersonal Intervention: A Pilot Study, Tamra Rasberry

Doctoral Dissertations and Projects

Relationship conflict for the psychiatric patient can have significant detrimental effects. There are specific types of interactions that can increase conflict and predict the potential for relapse; these have been identified by research and designated as components of Expressed Emotion (EE). Cognitive Behavioral Therapy (CBT) and Interpersonal Therapy (IPT) have been very effective when targeting specific psychiatric diagnoses, but less effective when addressing relationship conflict. The majority of studies addressing relationship conflict have taken place in an outpatient, long-term setting. There is limited research that utilizes an inpatient short-term intensive therapy with relationship conflict as its sole focus, targeting areas …

The Identification And Classification Of Flow Disruptions In The Operating Room During Laparoscopic Cholecystectomy And Open Hernia Repair Procedures, Sacha N. Duff

Doctoral Dissertations and Master's Theses

The operating room is one of the most complex work environments in healthcare; it is estimated that at least 7% of adverse events due to medical error occur in the operating room. Flow disruptions are events that cause a "break" in the primary surgical task, or the loss of any team member's situational awareness. An empirical link between flow disruptions and surgical errors in the OR has been established; therefore, identifying and classifying the specific flow disruptions present during different types of procedures should facilitate the development of evidence-based interventions. The goal of this study was to identify and classify …

Experiences Of Resident Assistants With Potentially Suicidal Students: Identification, Referral, And Expectations, Katherine M. Bender

Counseling & Human Services Theses & Dissertations

Resident Assistants (RAs), living on campus and tasked with advising students while keeping them safe, are in a position to identify and refer students who may be at risk for suicide or other mental health issues. This study examined RA ability to identify students at risk for suicide, RA comfort in working with students at risk for suicide, RA actions taken when working with students who may be at risk for suicide, and RA expectations for shared information about students the RAs have referred for counseling because they may be at risk for suicide. The study found that RAs report …

Child Emotional Abuse And Its Relationship To Obesity, Kelly Anderson Driscoll

Sociology & Criminal Justice Theses & Dissertations

Over the past 30 years in the United States childhood obesity has more than tripled (Center for Disease Control and Prevention, 2010). In 2008, 18.5% of adolescents of the age 12-18 years old were obese in the United States (Center for Disease Control and Prevention, 2010). With the increase of obesity Americans have spent approximately 9% of their total medical costs on obesity-related illnesses (Finkelstein, Fiebelkorn, &Wang, 2003). Previous research documented the relationship between virtually every form of child abuse and subsequent obesity. Restricting focus to child emotional abuse, while studies have linked emotional abuse to the long-term consequence of …

Empowerment-Based Positive Youth Development: A New Understanding Of Healthy Development For African American Youth, Raphael Travis Jr., Tamara Leech

Department of Public Health Scholarship and Creative Works

A shift occurred in research about adolescents in the general population. Research is moving away from deficits toward a resilience paradigm and understanding trajectories of positive youth development. This shift has been less consistent in research and practice with African American youth. A gap also exists in understanding whether individual youth development dimensions generate potential in other dimensions. This study presents an empowerment-based positive youth development model. It builds upon existing research to present a new vision of healthy development for African American youth that is strengths-based, developmental, culture-bound, and action-oriented. It emphasizes the relationship between person and environment, the …

Alternative Hospital Gift Bags And Breastfeeding Exclusivity, Yeon Bai, Shahla M. Wunderlich, Rickie Kashdan

Department of Nutrition and Food Studies Scholarship and Creative Works

The type of gift bags given to new mothers at the time of discharge from the hospital can influence their confidence in breastfeeding. Most hospitals in the US continue to distribute commercial gift bags containing formula samples despite the reported negative influence of commercial bags on the duration of breastfeeding. This study compared breastfeeding outcomes in women receiving three different kinds of gift bags at discharge. A prospective intervention study was conducted during the 2009-2010 in New Jersey. Three breastfeeding cohorts were recruited and assigned to three groups: COMMERCIAL received discharge bags containing formula samples, BF-INFO received breastfeeding information and …

Dynamic And Opposing Adjustment Of Movement Cancellation And Generation In An Oculomotor Countermanding Task., Brian D Corneil, Joshua C Cheng, Samanthi C Goonetilleke

Brain and Mind Institute Researchers' Publications

Adaptive adjustments of strategies help optimize behavior in a dynamic and uncertain world. Previous studies in the countermanding (or stop-signal) paradigm have detailed how reaction times (RTs) change with trial sequence, demonstrating adaptive control of movement generation. Comparatively little is known about the adaptive control of movement cancellation in the countermanding task, mainly because movement cancellation implies the absence of an outcome and estimates of movement cancellation require hundreds of trials. Here, we exploit a within-trial proxy of movement cancellation based on recordings of neck muscle activity while human subjects attempted to cancel large eye-head gaze shifts. On a subset …

Duel Or Diversion? Conscientiousness And Executive Function In The Prediction Of Health And Longevity, Tim Bogg, Brent W. Roberts

Psychology Faculty Research Publications

Response to Hall and Fong Letter to the Editor in Annals of Behavioral Medicine 45(3).

Two Distinct Ipsilateral Cortical Representations For Individuated Finger Movements., Jörn Diedrichsen, Tobias Wiestler, John W Krakauer

Brain and Mind Institute Researchers' Publications

Movements of the upper limb are controlled mostly through the contralateral hemisphere. Although overall activity changes in the ipsilateral motor cortex have been reported, their functional significance remains unclear. Using human functional imaging, we analyzed neural finger representations by studying differences in fine-grained activation patterns for single isometric finger presses. We demonstrate that cortical motor areas encode ipsilateral movements in 2 fundamentally different ways. During unimanual ipsilateral finger presses, primary sensory and motor cortices show, underneath global suppression, finger-specific activity patterns that are nearly identical to those elicited by contralateral mirror-symmetric action. This component vanishes when both motor cortices are …

The Effect Of Visual Suggestion On Exercise Motivation And Outcomes, Thomas G. Plante, Ashley Morisako, Justine Folk, Elizabeth Kay, Caroline Read, Ashley Dunn, Angel Perez, Eleanor Willemsen

Psychology

Theories of suggestion and motivation were used to examine if college students exercising in an environment with low or high motivation posters would affect mood, perceived exertion, and exercise workload (i.e., RPM and speed). A total of 134 students (62 males, 72 females) were randomly assigned to one of three conditions while exercising: relaxing posters (i.e., tropical nature), motivational posters (i.e., competitive bikers), or no posters (i.e., control). Participants completed 20 minutes of exercise at their own pace. Measures of mood were taken immediately prior to and following exercise. Exercise workload was recorded throughout. Results indicate that participants in the …

The Case For Conscientiousness: Evidence And Implications For A Personality Trait Marker Of Health And Longevity, Tim Bogg, Brent W. Roberts

Psychology Faculty Research Publications

Purpose Recent initiatives by major funding agencies have emphasized translational and personalized approaches (e.g., genetic testing) to health research and health management. While such directives are appropriate, and will likely produce tangible health benefits, we seek to highlight a confluence of several lines of research showing relations between the personality dimension of conscientiousness and a variety of health-related outcomes.

Methods Using a modified health process model, we review the compelling evidence linking conscientiousness to health and disease processes, including longevity, diseases, morbidity-related risk factors, health-related psycho-physiological mechanisms, health-related behaviors, and social environmental factors related to health.

Conclusion We argue the …

Alaska Winter's Relationship To Domestic Violence And Alcohol Abuse, Jennifer Marie Read

Geography and the Environment: Graduate Student Capstones

Alaska is known for its long, dark, cold winter months. Daylight savings time exists to cope with months that have little sunlight, but that still leaves on average, five hours of daylight. Special light bulbs exist to help with the darkness by providing light that tricks the body into thinking it is getting more sun than it really is. As daylight decreases, the weather turns colder; depression, alcohol, and domestic violence begin to rise. Studies show alcohol related crime and domestic violence occur more during the winter months in Alaska. This research paper will analyze the data pertaining to alcohol …

The Influence Of Mindful Attention On Value Claiming In Distributive Negotiations: Evidence From Four Laboratory Experiments, Jochen Reb, Jayanth Narayanan

Research Collection Lee Kong Chian School Of Business

We examined the effect of mindful attention on negotiation outcomes in distributive negotiations across four experiments. In Studies 1 and 2, participants who performed a short mindful attention exercise prior to the negotiation claimed a larger share of the bargaining zone than the control condition participants they negotiated with. Study 3 replicated this finding using a different manipulation of mindful attention. Study 4 again replicated this result and also found that mindful negotiators were more satisfied with both the outcome and the process of the negotiation. We discuss theoretical and practical implications, limitations, and future directions.

A Prospective Examination Of Mindfulness Training On The Mitigation Of Postraumatic Stress Symptoms, Abby E. Blankenship

Dissertations

The current study investigated the ability of a one-session computerized mindfulness intervention to mitigate posttraumatic stress disorder (PTSD)-like symptoms in response to a trauma analogue. Ninety-two participants were randomly assigned to either mindfulness training or no treatment. Participants assigned to the mindfulness training completed a 1-hour computerized mindfulness training and practiced their skills for 1 week. All participants were exposed to an analogue for real-life trauma and were assessed at 1- and 2-week follow-up. Participants assigned to the mindfulness condition exhibited significantly lower levels of PTSD-like symptoms at 2-week follow-up in comparison to the no treatment condition. In addition, participants …

Motivational Interviewing Assessment And Behavior Therapy As A Stepped-Care Approach To The Treatment Of Adolescent Depression, Tanya N. Douleh

Dissertations

Depression is a significant public health concern with a lifetime prevalence of 24.01 for adolescents in grades 9-12 (Lewinsohn, Hops, Roberts, Seeley, & Andrews, 1993) and a point prevalence of 4-6% (Kessler, Avenevoli, & Ries, 2001). The risks associated with adolescent onset depression include comorbidity, depressive episodes continuing into adulthood, and suicidality. These risks make it imperative to develop effective treatments to address adolescent depression. Stepped care is an approach to treatment which involves treatment of illness using the least invasive measures first and moving toward more invasive treatment as indicated by ongoing assessment. Through a single-participant design, the current …

Session 4-2-A: Taking The Disorder Out Of Gambling Disorder, Denise F. Quirk, Colin M. Hodgen

International Conference on Gambling & Risk Taking

DSM‐5 Gambling Disorder

A. Persistent and recurrent problematic gambling behavior leading to clinically significant impairment or distress, as indicated by four (or more) of the following in a 12‐month period:

A. Persistent and recurrent maladaptive gambling behavior as indicated by five (or more) of the following:

Session 4-2-C: Does Non-Problem Gaming Have Any Negative Impact On Gamblers?, Samuel Huang

International Conference on Gambling & Risk Taking

Outline

Background

Literature Review

Data and Methodology

Analysis and Discussion

Session 4-1-D: The Experience Of Lotto 6/49 And The Capacity To Trust: Elements For An Anthropology Of Gambling, Jocelyn Gadbois

International Conference on Gambling & Risk Taking

Anthropologists study Lotto 6/49 as an experience.

Lévy-Bruhl tries to compare the magical beliefs of serious gamblers with the magical beliefs of individuals he refers to as the ‘‘primitives’’ (1924).

After that, Henslin studied the superstitions of St.Louis taxi drivers who play craps during their work breaks and compared them to Skinner’s pigeon (1967).

I wanted in my thesis to help anthropology to reconstruct lost knowledge regarding gambling and beliefs about magic in capitalist society.

Session 4-1-C: Social Gaming: Problems, Policies And Predictions, Keith Whyte

International Conference on Gambling & Risk Taking

Discusses key issues with social gaming.

Session 4-1-A: Roman Addiction: The Changing Perception Of Problem Gaming In The Roman World, Suzanne B. Faris

International Conference on Gambling & Risk Taking

Describes the perception of problem gambling in ancient Rome.

Session 4-1-C: Social Media Gambling Games: Impact On Young People, Sally Gainsbury, Jeffrey L. Derevensky

International Conference on Gambling & Risk Taking

Key concerns for youth

Normalisation & positive impressions of gambling

Misrepresenting the odds of winning

Encouraging transition to real money gambling

Development of problems

Session 4-1-A: The Problem Gambling Center, Robert Hunter

International Conference on Gambling & Risk Taking

Provides information and statistics on the Problem Gambling Center.

Session 3-4-A: Public Opinion And Problem Gambling, Don Feeney

International Conference on Gambling & Risk Taking

What do we need to know?

How does the public perceive addiction?

Do they stigmatize addiction?

Do they recognize gambling addiction?

Do they understand the causes?

Do they understand the solutions?

Do they know where to go for help?

Do they know preventative factors?

What are they willing to do?

What messages are credible and appealing?

Session 3-4-C: Are Lottery Players Affected By Random Shocks? Evidence From China’S Individual Lottery Betting Panel Data, Jia Yuan

International Conference on Gambling & Risk Taking

I explore a unique, individual level, lottery betting panel data and show that lottery gambling is significantly affected by lottery winning history even though this winning history is shown to be merely an exogenous random shock. This panel data records lottery players’ collective lottery betting behaviors on a Chinese online lottery purchase website. This website lists each player’s lottery investment performance, the ratio between the lottery return and the lottery investment in the past three months, for lottery players’ reference and this ratio is shown to be an independent random shock across players. Based on the data with around 400,000 …

Session 3-3-D: Interactive Gambling In Australia, Sally Gainsbury, Nerilee Hing, Alex Russell, Alex Blaszczynski, Dan Lubman, Robert Wood

International Conference on Gambling & Risk Taking

Describes interactive gambling and gives its advantages and disadvantages.

Session 3-3-A: An Improved Pathways Development Model Of Problem Gambling: A Summary Of 11 Studies In Hong Kong And Macau, Amy Chiu Sau Lam, Alice Chan Ying Ying, Chi Chuen Chan

International Conference on Gambling & Risk Taking

Introduction

The rationale of this study came from a casual meeting of our supervisor Dr. Chan Chi Chuen and Professor Blaszczynski on a bus after the 2009 Reno conference.

On the bus, C. C. promised Mr. Blaszczynski that he would validate the pathways model in Hong Kong and Macau. And in the next 5 years, Dr. C.C. Chan and his students conducted 11 research projects on problem gambling in Hong Kong and Macau.

Purposes of current study

• To arrive on a summary finding from 11 studies on problem gambling
• To validate the pathways development model proposed by Blaszczynski & Nower …